Research Topics
| Erwin P StolzSummaryAffiliation: University of Giessen Country: Germany Publications
| Collaborators
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Detail Information
Publications
Cerebral vein thrombosis: clinical manifestation and diagnosisChristian Tanislav
Department of Neurology, Justus Liebig University, Giessen, Germany
BMC Neurol 11:69. 2011..Cerebral venous thrombosis (CVT) is a disease with a wide spectrum of symptoms and severity. In this study we analysed the predictive value of clinical signs and symptoms and the contribution of D-dimer measurements for diagnosis...- Evaluation of the middle cerebral artery occlusion techniques in the rat by in-vitro 3-dimensional micro- and nano computed tomographyAlexander C Langheinrich
Department of Radiology, Justus Liebig University Giessen, Giessen, Germany
BMC Neurol 10:36. 2010.... - Transcranial sonography for diagnosis of Parkinson's diseaseSabine Mehnert
Department of Neurology, Justus Liebig University of Giessen, Giessen, Germany
BMC Neurol 10:9. 2010..Therefore our study was conducted to test the reliability of this method by using a different ultrasound device and examining a large population of control and IPD subjects by two examiners to calculate interobserver reliability... - Decrease in shunt volume in patients with cryptogenic stroke and patent foramen ovaleChristian Tanislav
Department of Neurology, Justus Liebig University, Giessen, Germany
BMC Neurol 10:123. 2010..Proven, this could have implications for the care of patients with PFO and a history of stroke. The following study addressed this hypothesis in a cohort of patients with stroke and PFO... 
Can early neurosonology predict outcome in acute stroke?: a metaanalysis of prognostic clinical effect sizes related to the vascular statusErwin Stolz
Department of Neurology, Justus Liebig University, Giessen, Germany
Stroke 39:3255-61. 2008..Prediction of short- and long-term prognosis is an important issue in acute stroke care. This metaanalysis explores the prognostic value of initial bed-side transcranial ultrasound in acute stroke...
Cerebral venous thrombosis: an all or nothing disease? Prognostic factors and long-term outcomeErwin Stolz
Department of Neurology, Justus Liebig University, Am Steg 14, D 35385 Giessen, Germany
Clin Neurol Neurosurg 107:99-107. 2005..There is insufficient data on short- and especially long-term prognosis of cerebral venous thrombosis (CVT)...- Intracranial venous hemodynamics in patients with midline dislocation due to postischemic brain edemaErwin Stolz
Department of Neurology, Justus Liebig University, Giessen, Germany
Stroke 33:479-85. 2002..Therefore, changes in venous flow velocities are to be expected because of changes in intracranial pressure and brain tissue dislocation in patients with ischemic stroke and space-occupying brain edema... - Cerebral veins and sinusesErwin Stolz
Department of Neurology, Justus Liebig University, Giessen, Germany
Front Neurol Neurosci 21:182-93. 2006..It was not until the mid-1990s that venous transcranial ultrasound in adults was systematically developed. In the following the examination technique and clinical applications of this technique are summarized... - Role of ultrasound in diagnosis and management of cerebral vein and sinus thrombosisErwin P Stolz
Department of Neurology, Justus Liebig University, Am Steg 14, Giessen, Germany
Front Neurol Neurosci 23:112-21. 2008..However, ultrasonographic techniques are not sensitive enough to exclude cerebral venous thrombosis, but they may complement other imaging techniques. In the follow-up, sonographic findings are related to the functional outcome... - Cranial venous outflow under lower body positive and negative pressure conditions and head-up and -down tiltsErwin Stolz
Department of Neurology, Justus Liebig University, Giessen, Germany
J Neuroimaging 19:31-6. 2009..Although there exists a large body of knowledge on the regulation of arterial cerebral hemodynamics, little is known about the cerebral venous outflow (CVO)... - Active regulation of cerebral venous tone: simultaneous arterial and venous transcranial Doppler sonography during a Valsalva manoeuvreErwin Stolz
Department of Neurology, Justus Liebig University, Am Steg 14, 35385 Giessen, Germany
Eur J Appl Physiol 109:691-7. 2010..However, the significantly lager venous than the arterial overshoot in phase IV may be explained by the active regulation of the venous tone... - Anemia as a risk factor for cerebral venous thrombosis? An old hypothesis revisited. Results of a prospective studyErwin Stolz
Dept of Neurology, Justus Liebig University, Am Steg 14, 35385 Giessen, Germany
J Neurol 254:729-34. 2007..Several case reports have linked iron deficiency anemia with the occurrence of cerebral venous thrombosis (CVT) or stroke, yet, it is unclear whether this is a chance association... - Assessment of intracranial venous hemodynamics in normal individuals and patients with cerebral venous thrombosisE Stolz
Department of Neurology, Justus Liebig University, Giessen, Germany
Stroke 30:70-5. 1999..We evaluated the diagnostic value of both noncontrast and contrast-enhanced TCCS by comparing normal volunteers and patients with acute cerebral venous thrombosis... - Sonographic harmonic grey scale imaging of brain perfusion: scope of a new method demonstrated in selected casesE Stolz
Department of Neurology, Justus Liebig University, Giessen, Germany
Ultraschall Med 23:320-4. 2002..Transient response harmonic transcranial sonography is a new bed-side technique which provides information on brain tissue perfusion. This paper demonstrates the scope of perfusion transcranial sonography (p-TCS)... - Transcranial color-coded duplex sonography of intracranial veins and sinuses in adults. Reference data from 130 volunteersE Stolz
Departments of Neurology, Justus Liebeg University, Giessen, Germany
Stroke 30:1070-5. 1999..This study reports a standardized examination protocol for venous TCCS and provides reference data for clinical application... - Three-dimensional transcranial colour-coded duplex sonography of the transverse sinusE Stolz
Department of Neurology, Justus Liebig University, Am Steg 14, D 35385 Giessen, Germany
Eur J Neurol 7:581-3. 2000..TCCS with three-dimensional image reconstruction allowed a more precise spatial localization of venous flow signals in the posterior fossa and facilitated the understanding of the haemodynamics of the venous collateral network... - High-dose corticosteroid treatment is associated with an increased risk of developing cerebral venous thrombosisErwin Stolz
Department of Neurology, , Giessen, Germany
Eur Neurol 49:247-8. 2003 - Assessment of intracranial collateral flow by transcranial color-coded duplex sonography using a temporal and frontal axial insonation planeErwin Stolz
Department of Neurology, Justus Liebig University, Am Steg 14, D 35385 Giessen, Germany
J Neuroimaging 12:136-43. 2002..This study evaluated the TBW and LFBW for the assessment of collateral intracranial flow conditions and aimed at defining diagnostic transcranial color-coded duplex sonography (TCCS) criteria that do not need compression maneuvers... - Influence of recanalization on outcome in dural sinus thrombosis: a prospective studyErwin Stolz
Department of Neurology, Justus Liebig University, Giessen, Germany
Stroke 35:544-7. 2004..Recanalization in dural sinus thrombosis (DST) has been observed previously; however, systematic prospective data are lacking. The influence of recanalization on DST outcome has not yet been thoroughly evaluated... - Frontal bone windows for transcranial color-coded duplex sonographyE Stolz
Department of Neurology, Justus Liebig University, Giessen, Germany
Stroke 30:814-20. 1999..However, transorbital TCCS raises problems with the insonation of the orbital lens. To overcome these drawbacks, we studied the feasibility of frontal bone windows for TCCS examinations... - Interobserver and intraobserver reliability of venous transcranial color-coded flow velocity measurementsE Stolz
Department of Neurology, Justus Liebig University, Am Steg 14, D 35385 Giessen, Germany
J Neuroimaging 11:385-92. 2001..Venous transcranial color-coded duplex sonography is a new technique for noninvasive evaluation of the intracranial venous system. However, the interobserver and intraobserver reliability of this method is unclear... - Intracranial venous hemodynamics is a factor related to a favorable outcome in cerebral venous thrombosisErwin Stolz
Department of Neurology, Justus Liebig University, Giessen, Germany
Stroke 33:1645-50. 2002..However, it is conceivable that the presence or absence and the efficiency of venous collaterals, as well as recanalization, may have an impact on brain tissue damage and hence on the prognosis of acute CVT... - Reversible MR imaging abnormalities following cerebral venous thrombosisCarina Rottger
Department of Neurology Justus Liebig University, Giessen, Germany
AJNR Am J Neuroradiol 26:607-13. 2005..Our purpose was to study the time-dependent changes of venous infarcts on MR images and to define the variables that influence lesion volume in humans... - A new model of reversible sinus sagittalis superior thrombosis in the rat: magnetic resonance imaging changesCarina Rottger
Department of Neurology, Justus Liebig University, Giessen, Germany
Neurosurgery 57:573-80; discussion 573-80. 2005.... - Intravenous immunoglobulin reduces infarct volume but not edema formation in acute strokeMaureen Walberer
Department of Neurology, University Hospital Cologne, Cologne, Germany
Neuroimmunomodulation 17:97-102. 2010..Since edema treatment can provide secondary neuroprotective effects, we conducted the present study to evaluate whether edema reduction is the underlying cause of the neuroprotective properties of IVIG in experimental stroke... - Identification of embolic stroke patterns by diffusion-weighted MRI in clinically defined lacunar stroke syndromesTiemo Wessels
Department of Neurology, Justus Liebig University of Giessen, Germany
Stroke 36:757-61. 2005..To verify the reliability of the clinical diagnosis "lacunar syndrome," the value was investigated with diffusion-weighted MRI (DWI)... - In vitro evaluation of the sinus sagittalis superior thrombosis model in the rat using 3D micro- and nanocomputed tomographyAlexander Claus Langheinrich
Department of Radiology, Justus Liebig University Giessen, Klinikstrasse 36, Giessen, Germany
Neuroradiology 52:815-21. 2010..Therefore, the purpose of our study was to evaluate a well-established model for sinus sagittalis (SSS) thrombosis using micro- and nanocomputed tomography (CT) imaging... - Consensus recommendations for transcranial color-coded duplex sonography for the assessment of intracranial arteries in clinical trials on acute strokeMax Nedelmann
Department of Neurology, Justus Liebig University, Giessen, Germany
Stroke 40:3238-44. 2009..The aim of this international consensus procedure was to develop recommendations on the methodology and documentation to be used for assessment of intracranial occlusion and for monitoring of recanalization... - Is heparin treatment the optimal management for cerebral venous thrombosis? Effect of abciximab, recombinant tissue plasminogen activator, and enoxaparin in experimentally induced superior sagittal sinus thrombosisCarina Rottger
Department of Neurology, Justus Liebig University, Giessen, Germany
Stroke 36:841-6. 2005..Based on a newly developed model of reversible superior sagittal sinus (SSS) thrombosis in the rat, we investigated the effect of thrombolytic and anticoagulant treatment on recanalization, brain parenchymal changes, and motor deficits... - Torticollis under cyclobenzaprineReinhard Reuss
Department of Neurology, Justus Liebig University Giessen, Giessen, Germany
Pharmacology 84:91-2. 2009..This case might be additional evidence for the necessity of appropriate dosage in case of liver impairment. Secondly there are possibly consequences as regards the therapy of motor side effects... - Middle cerebral artery occlusion during MR-imaging: investigation of the hyperacute phase of stroke using a new in-bore occlusion model in ratsTibo Gerriets
Department of Radiology Experimental Neurology Research Group Kerckhoff Klinik Bad Nauheim, Germany
Brain Res Brain Res Protoc 12:137-43. 2004..It does not permit reperfusion. This technique might provide information about the pathophysiological processes in the hyperacute phase of stroke... - Sinus thrombosis after a jump from a small rock and a sneezing attack: minor endothelial trauma as a precipitating factor for cerebral venous thrombosis?Carina Rottger
Department of Neurology, University of Giessen, Germany
Headache 44:812-5. 2004..In about 20% of CVT cases the cause remains unclear. As minor head trauma may not have been recognized during history taking, this may represent a so far under-recognized precipitating factor for CVT... - Conservative medical treatment and intravenous thrombolysis in acute stroke from carotid T occlusionMichael T Wunderlich
Department of Neurology, Otto von Guericke University Magdeburg, Germany
Cerebrovasc Dis 20:355-61. 2005..We aimed to analyse the course of early recanalization and corresponding functional outcome in patients with an acute occlusion of the carotid T who were treated conservatively or underwent intravenous thrombolysis... - A sudden arterial blood pressure decrease is compensated by an increase in intracranial blood volumeBernhard Rosengarten
Justus-Liebig-University, Department of Neurology, Am Steg 14, 35385 Giessen, Germany
J Neurol 249:538-41. 2002..The increase in intracranial blood volume might be of clinical relevance in orthostatic dysregulation by increasing the ischemic tolerance of the brain before cerebral autoregulation becomes effective... - Midline-shift corresponds to the amount of brain edema early after hemispheric stroke--an MRI study in ratsMaureen Walberer
Department of Neurology, University Giessen, Giessen, Germany
J Neurosurg Anesthesiol 19:105-10. 2007..MLS quantification can be regarded as an easily assessable and valid global quantitative parameter for brain edema and thus might facilitate the surgical and nonsurgical management of edema in acute stroke patients... - A rat model for cerebral air microembolisationTibo Gerriets
Department of Neurology, Experimental Neurology Research Group, Justus Liebig University Giessen, Germany
J Neurosci Methods 190:10-3. 2010..In conclusion, the method presented allows injecting air bubbles of defined number and diameter into cerebral arteries of rats. This technique facilitates animal research in the field of air embolisation... - Extracellular RNA mediates endothelial-cell permeability via vascular endothelial growth factorSilvia Fischer
Department of Biochemistry Medical School, Justus Liebig University, Giessen, Germany
Blood 110:2457-65. 2007..Together, these results identify extracellular RNA as a novel natural permeability factor, upstream of VEGF, whereas counteracting RNase treatment may serve as new vessel-protective modality... - Interferon-beta 1b leads to a short-term increase of soluble but long-term stabilisation of cell surface bound adhesion molecules in multiple sclerosisJoerg Kraus
Justus Liebig University of Giessen, Dept of Neurology, 35385 Giessen, Germany
J Neurol 251:464-72. 2004..Stabilisation of the expression of cell surface bound AMs on blood MNC may indicate the beneficial effects of IFN-beta1b therapy in MS patients... - Prognostic value of transcranial sonography in acute stroke patientsManfred Kaps
Department of Neurology, Justus Liebig University Giessen, Giessen, Germany
Eur Neurol 59:9-16. 2008..Finally, transcranial ultrasound can be used to gauge the appropriateness of more complex and costly imaging studies, thereby optimizing utilization of health care resources... - Strategies for the reduction of cerebral microembolism during transmyocardial laser revascularizationTibo Gerriets
Department of Neurology, Justus-Liebig University Giessen, 35390 Giessen, Germany
Lasers Surg Med 34:379-84. 2004..Laser-induces cavitation-effects lead to an additional release of nitrogen bubbles. Thus, the microembolic load can be reduced by ventilation with 100% oxygen and by decreasing the laser energy... - Diffusion-weighted magnetic resonance imaging and neurobiochemical markers after aortic valve replacement: implications for future neuroprotective trials?Erwin Stolz
Department of Neurology, Justus Liebig University, Giessen, Germany
Stroke 35:888-92. 2004..In this study, we evaluated postoperative diffusion-weighted imaging (DWI) as a potential surrogate marker for brain embolism and its relationship to neurobiochemical markers of brain injury...