Verena Steinke

Summary

Affiliation: University of Bonn
Country: Germany

Publications

  1. pmc Hereditary nonpolyposis colorectal cancer (HNPCC)/Lynch syndrome
    Verena Steinke
    Institute of Human Genetics, University of Bonn, Germany
    Dtsch Arztebl Int 110:32-8. 2013
  2. pmc Polymorphisms of genes coding for ghrelin and its receptor in relation to colorectal cancer risk: a two-step gene-wide case-control study
    Daniele Campa
    Genomic Epidemiology Group, German Cancer Research Center DKFZ, Im Neuenheimer Feld 280, D 69120 Heidelberg, Germany
    BMC Gastroenterol 10:112. 2010
  3. doi request reprint No association between MUTYH and MSH6 germline mutations in 64 HNPCC patients
    Verena Steinke
    Institute of Human Genetics, University of Bonn, Bonn, Germany
    Eur J Hum Genet 16:587-92. 2008
  4. doi request reprint Compound heterozygosity for two MSH6 mutations in a patient with early onset colorectal cancer, vitiligo and systemic lupus erythematosus
    Nils Rahner
    Institute of Human Genetics, University of Bonn, Bonn, Germany
    Am J Med Genet A 146:1314-9. 2008
  5. ncbi request reprint Evaluating the performance of clinical criteria for predicting mismatch repair gene mutations in Lynch syndrome: a comprehensive analysis of 3,671 families
    Verena Steinke
    Institute of Human Genetics, University of Bonn, Bonn, Germany
    Int J Cancer 135:69-77. 2014
  6. doi request reprint Expanded extracolonic tumor spectrum in MUTYH-associated polyposis
    Stefanie Vogt
    Institute of Human Genetics, University of Bonn, Bonn, Germany
    Gastroenterology 137:1976-85.e1-10. 2009
  7. ncbi request reprint Nine novel pathogenic germline mutations in MLH1, MSH2, MSH6 and PMS2 in families with Lynch syndrome
    Nils Rahner
    Institute of Human Genetics, University of Bonn, Germany
    Acta Oncol 46:763-9. 2007
  8. doi request reprint FHL2 expression in peritumoural fibroblasts correlates with lymphatic metastasis in sporadic but not in HNPCC-associated colon cancer
    Lucia Gullotti
    Institute of Pathology, University of Bonn Medical School, Bonn, Germany
    Lab Invest 91:1695-705. 2011
  9. doi request reprint Mutation and association analyses of the candidate genes ESR1, ESR2, MAX, PCNA, and KAT2A in patients with unexplained MSH2-deficient tumors
    Nils Rahner
    Institute of Human Genetics, BMZ, University of Bonn, Sigmund Freud Strasse 25, 53127, Bonn, Germany
    Fam Cancer 11:19-26. 2012

Collaborators

Detail Information

Publications9

  1. pmc Hereditary nonpolyposis colorectal cancer (HNPCC)/Lynch syndrome
    Verena Steinke
    Institute of Human Genetics, University of Bonn, Germany
    Dtsch Arztebl Int 110:32-8. 2013
    ..Diagnostic evaluations for Lynch syndrome should be carried out with appropriate genetic counseling...
  2. pmc Polymorphisms of genes coding for ghrelin and its receptor in relation to colorectal cancer risk: a two-step gene-wide case-control study
    Daniele Campa
    Genomic Epidemiology Group, German Cancer Research Center DKFZ, Im Neuenheimer Feld 280, D 69120 Heidelberg, Germany
    BMC Gastroenterol 10:112. 2010
    ..Accumulating evidence also indicates a role of ghrelin in cancer development...
  3. doi request reprint No association between MUTYH and MSH6 germline mutations in 64 HNPCC patients
    Verena Steinke
    Institute of Human Genetics, University of Bonn, Bonn, Germany
    Eur J Hum Genet 16:587-92. 2008
    ..30) nor in different subgroups regarding mutation type. Our results do not support the association between MSH6 mutations and heterozygosity for MUTYH mutations...
  4. doi request reprint Compound heterozygosity for two MSH6 mutations in a patient with early onset colorectal cancer, vitiligo and systemic lupus erythematosus
    Nils Rahner
    Institute of Human Genetics, University of Bonn, Bonn, Germany
    Am J Med Genet A 146:1314-9. 2008
    ....
  5. ncbi request reprint Evaluating the performance of clinical criteria for predicting mismatch repair gene mutations in Lynch syndrome: a comprehensive analysis of 3,671 families
    Verena Steinke
    Institute of Human Genetics, University of Bonn, Bonn, Germany
    Int J Cancer 135:69-77. 2014
    ..Familial clustering of Lynch syndrome-related tumors, early age of onset, and familial occurrence of small-bowel cancer were clinically relevant predictors for Lynch syndrome. ..
  6. doi request reprint Expanded extracolonic tumor spectrum in MUTYH-associated polyposis
    Stefanie Vogt
    Institute of Human Genetics, University of Bonn, Bonn, Germany
    Gastroenterology 137:1976-85.e1-10. 2009
    ..MUTYH-associated polyposis (MAP) is characterized by a lifetime risk of colorectal cancer of up to 100%. However, no systematic evaluation of extracolonic manifestations has been reported...
  7. ncbi request reprint Nine novel pathogenic germline mutations in MLH1, MSH2, MSH6 and PMS2 in families with Lynch syndrome
    Nils Rahner
    Institute of Human Genetics, University of Bonn, Germany
    Acta Oncol 46:763-9. 2007
    ..The findings underline the importance of a pre-screening of tumor tissue for an efficient definition of conspicuous cases...
  8. doi request reprint FHL2 expression in peritumoural fibroblasts correlates with lymphatic metastasis in sporadic but not in HNPCC-associated colon cancer
    Lucia Gullotti
    Institute of Pathology, University of Bonn Medical School, Bonn, Germany
    Lab Invest 91:1695-705. 2011
    ..These findings are absent in HNPCC-associated colon cancers in vivo and may contribute to a less invasive and more protruding tumour margin of microsatellite instable carcinomas...
  9. doi request reprint Mutation and association analyses of the candidate genes ESR1, ESR2, MAX, PCNA, and KAT2A in patients with unexplained MSH2-deficient tumors
    Nils Rahner
    Institute of Human Genetics, BMZ, University of Bonn, Sigmund Freud Strasse 25, 53127, Bonn, Germany
    Fam Cancer 11:19-26. 2012
    ..The present results suggest that neither rare nor common genetic variants in ESR1, ESR2, MAX, PCNA, or KAT2A contribute to the development of Lynch syndrome...