H Stefan

Summary

Affiliation: University of Erlangen-Nuremberg
Country: Germany

Publications

  1. pmc Epileptic neuronal networks: methods of identification and clinical relevance
    Hermann Stefan
    Department of Neurology, University Hospital Erlangen Erlangen, Bavaria, Germany
    Front Neurol 4:8. 2013
  2. doi request reprint Transcutaneous vagus nerve stimulation (t-VNS) in pharmacoresistant epilepsies: a proof of concept trial
    Hermann Stefan
    Department of Neurology Epilepsy Center, University Hospital Erlangen, Erlangen, Germany
    Epilepsia 53:e115-8. 2012
  3. doi request reprint [Cognition and epilepsies]
    H Stefan
    Epilepsiezentrum Neurologische Klinik, Universitatsklinikum Erlangen, Schwabachanlage 6, 91054, Erlangen, Germany
    Nervenarzt 79:77-91; quiz 92. 2008
  4. doi request reprint Increased spike frequency during general anesthesia with etomidate for magnetoencephalography in patients with focal epilepsies
    Hermann Stefan
    Epilepsy Center, Department of Neurology, University Hospital Erlangen, Erlangen, Germany
    Clin Neurophysiol 121:1220-6. 2010
  5. doi request reprint Clinical prediction of postoperative seizure control: structural, functional findings and disease histories
    H Stefan
    Epilepsy Centre, Department of Neurology, University Hospital Erlangen, Schwabachanalage 6, 91054 Erlangen, Germany
    J Neurol Neurosurg Psychiatry 80:196-200. 2009
  6. doi request reprint Magnetoencephalography adds to the surgical evaluation process
    H Stefan
    Epilepsy Center, Neurological Clinic, University Hospital Erlangen Nuremberg at Erlangen, Erlangen, Germany
    Epilepsy Behav 20:172-7. 2011
  7. doi request reprint Objective quantification of seizure frequency and treatment success via long-term outpatient video-EEG monitoring: a feasibility study
    H Stefan
    University Hospital Erlangen, Epilepsy Centre, Germany
    Seizure 20:97-100. 2011
  8. doi request reprint Epilepsy in the elderly: facts and challenges
    H Stefan
    University Hospital Erlangen, Epilepsy Center, Germany
    Acta Neurol Scand 124:223-37. 2011
  9. doi request reprint Epilepsy monitoring for therapy: challenges and perspectives
    H Stefan
    Epilepsy Center, Department of Neurology, University Hospital Erlangen, Schwabachanlage 6, 91054 Erlangen, Germany
    Clin Neurophysiol 120:653-8. 2009
  10. doi request reprint MEG in frontal lobe epilepsies: localization and postoperative outcome
    Hermann Stefan
    Neurological Clinic, University Hospital Erlangen, Erlangen, Germany
    Epilepsia 52:2233-8. 2011

Detail Information

Publications76

  1. pmc Epileptic neuronal networks: methods of identification and clinical relevance
    Hermann Stefan
    Department of Neurology, University Hospital Erlangen Erlangen, Bavaria, Germany
    Front Neurol 4:8. 2013
    ..Finally new approaches to delineate epileptogenic networks are discussed...
  2. doi request reprint Transcutaneous vagus nerve stimulation (t-VNS) in pharmacoresistant epilepsies: a proof of concept trial
    Hermann Stefan
    Department of Neurology Epilepsy Center, University Hospital Erlangen, Erlangen, Germany
    Epilepsia 53:e115-8. 2012
    ..The noninvasive t-VNS stimulation is a safe and well-tolerated method for relatively long periods, and might be an alternative treatment option for patients with epilepsy...
  3. doi request reprint [Cognition and epilepsies]
    H Stefan
    Epilepsiezentrum Neurologische Klinik, Universitatsklinikum Erlangen, Schwabachanlage 6, 91054, Erlangen, Germany
    Nervenarzt 79:77-91; quiz 92. 2008
    ..The need of individual assessment of cognitive side effects draws increasing attention as a precondition for treatment optimized to each patient...
  4. doi request reprint Increased spike frequency during general anesthesia with etomidate for magnetoencephalography in patients with focal epilepsies
    Hermann Stefan
    Epilepsy Center, Department of Neurology, University Hospital Erlangen, Erlangen, Germany
    Clin Neurophysiol 121:1220-6. 2010
    ..Magnetoencephalography (MEG) is used for focus localization in presurgical evaluation of patients with focal epilepsies. In this proof-of-concept study, general anesthesia with etomidate was used to improve effectiveness of MEG-recordings...
  5. doi request reprint Clinical prediction of postoperative seizure control: structural, functional findings and disease histories
    H Stefan
    Epilepsy Centre, Department of Neurology, University Hospital Erlangen, Schwabachanalage 6, 91054 Erlangen, Germany
    J Neurol Neurosurg Psychiatry 80:196-200. 2009
    ..Mesial temporal lobe epilepsy (MTLE) constitutes a heterogenic entity with different clinical histories, pathomorphological hippocampal findings and varying postoperative outcome...
  6. doi request reprint Magnetoencephalography adds to the surgical evaluation process
    H Stefan
    Epilepsy Center, Neurological Clinic, University Hospital Erlangen Nuremberg at Erlangen, Erlangen, Germany
    Epilepsy Behav 20:172-7. 2011
    ..The main conclusion is that the largest role of MEG, as presently performed in the clinical environment, is to increase the number of patients who can go on to surgery, while it should not be used to deny surgery to any patient...
  7. doi request reprint Objective quantification of seizure frequency and treatment success via long-term outpatient video-EEG monitoring: a feasibility study
    H Stefan
    University Hospital Erlangen, Epilepsy Centre, Germany
    Seizure 20:97-100. 2011
    ..Outpatient monitoring may be helpful to guide treatment for severe epilepsies and offers the possibility to more reliably quantify the efficacy of treatment in the long-term, even over several months...
  8. doi request reprint Epilepsy in the elderly: facts and challenges
    H Stefan
    University Hospital Erlangen, Epilepsy Center, Germany
    Acta Neurol Scand 124:223-37. 2011
    ..Novel antiepileptic drugs are necessary as current antiepileptics have strong interaction potentials and harmful side effects, making them ill-suboptimal for treating epilepsy in the elderly...
  9. doi request reprint Epilepsy monitoring for therapy: challenges and perspectives
    H Stefan
    Epilepsy Center, Department of Neurology, University Hospital Erlangen, Schwabachanlage 6, 91054 Erlangen, Germany
    Clin Neurophysiol 120:653-8. 2009
    ..These methods can be of assistance, as essential and practical tools, in the decision making during diagnostic monitoring by providing more objective results...
  10. doi request reprint MEG in frontal lobe epilepsies: localization and postoperative outcome
    Hermann Stefan
    Neurological Clinic, University Hospital Erlangen, Erlangen, Germany
    Epilepsia 52:2233-8. 2011
    ..This study aimed to analyze magnetoencephalography (MEG) localizations of epileptic clusters in different cortical regions of the frontal lobe and relate these findings to postoperative outcomes associated with frontal lobe epilepsy (FLE)...
  11. doi request reprint [Current clinical-neurophysiological findings in absence epilepsies]
    H Stefan
    Epilepsiezentrum Erlangen Neurologie, Universitatsklinik, Erlangen, Germany
    Nervenarzt 80:378-85. 2009
    ..These must be distinguished from a pure culture of focal frontal lobe epilepsies, which can also be accompanied by the lead symptom of absences...
  12. doi request reprint Network characteristics of idiopathic generalized epilepsies in combined MEG/EEG
    Hermann Stefan
    University Hospital Erlangen, Epilepsy Center Department of Neurology, Schwabachanlage 6, 91054 Erlangen, Germany
    Epilepsy Res 85:187-98. 2009
    ....
  13. doi request reprint Interictal triple ECoG characteristics of temporal lobe epilepsies: An intraoperative ECoG analysis correlated with surgical outcome
    H Stefan
    Epilepsy Center, Department of Neurology, University Hospital Erlangen, Schwabachanlage 6, 91054 Erlangen, Germany
    Clin Neurophysiol 119:642-52. 2008
    ..We have systematically investigated different characteristic epileptiform activities in intraoperative ECoG and correlated them to postoperative outcome...
  14. doi request reprint Magnetic source imaging
    H Stefan
    University Hospital Erlangen, Epilepsy Center Neurological Clinic, Germany
    Rev Neurol (Paris) 165:742-5. 2009
    ..This report presents an overview of the technique, as well as its advantages and limitations in the clinical context of epileptology...
  15. doi request reprint Multi-voxel magnetic resonance spectroscopy at 3 T in patients with idiopathic generalised epilepsy
    M T Doelken
    Department of Neuroradiology, University of Erlangen Nuremberg, Erlangen, Germany
    Seizure 19:485-92. 2010
    ..The extent of regional metabolic involvement perhaps indicates the key structures in generation of seizures and involvement of specific network of dysfunction...
  16. doi request reprint (1)H-MRS profile in MRI positive- versus MRI negative patients with temporal lobe epilepsy
    M T Doelken
    Department of Neuroradiology, University of Erlangen Nuremberg, Schwabachanlage 6, 91054 Erlangen, Germany
    Seizure 17:490-7. 2008
    ....
  17. ncbi request reprint Magnetic resonance spectroscopy and histopathological findings in temporal lobe epilepsy
    H Stefan
    Department of Neurology, University Erlangen Nurnberg, Schwabachanlange 6, 90154 Erlangen, Germany
    Epilepsia 42:41-6. 2001
    ....
  18. ncbi request reprint Epilepsy surgery, resection volume and MSI localization in lesional frontal lobe epilepsy
    A Genow
    Neurological Clinic, Department of Neurology, Epilepsy Center, University Erlangen Nurnberg, D 91054, Erlangen, Germany
    Neuroimage 21:444-9. 2004
    ..Our results in five cases with lesional frontal lobe epilepsy showed that good surgical outcome could be achieved in those patients where the majority of MEG spike localizations were located within the resected brain volume...
  19. doi request reprint Multimodality approach in cryptogenic epilepsy with focus on morphometric 3T MRI
    M T Doelken
    Department of Neuroradiology, Friedrich Alexander University of Erlangen Nuremberg, Schwabachanlage 6, 91054 Erlangen, Germany
    J Neuroradiol 39:87-96. 2012
    ..This study aimed to investigate the potential contribution of morphometric MRI analysis in comparison to other modalities, such as MEG, SPECT and PET, in identifying the epileptogenic focus in patients with cryptogenic epilepsy...
  20. ncbi request reprint Magnetic brain source imaging of focal epileptic activity: a synopsis of 455 cases
    H Stefan
    Department of Neurology, Epilepsy Center, University of Erlangen Nuernberg, Germany
    Brain 126:2396-405. 2003
    ..Accuracy as well as contribution findings underlined MSI appropriateness even for extratemporal epilepsies, which otherwise frequently prove difficult with respect to focus localization...
  21. doi request reprint Interictal magnetoencephalography used in magnetic resonance imaging-negative patients with epilepsy
    X T Wu
    Neurological Clinic, University Hospital Erlangen, Erlangen, Germany
    Acta Neurol Scand 127:274-80. 2013
    ..This study aims to investigate the contributions of magnetoencephalography (MEG) in magnetic resonance imaging (MRI)-negative patients...
  22. ncbi request reprint Therapeutic intensive seizure analysis (TISA) in presurgical evaluation of Losigamone
    H Stefan
    Department of Neurology, Epilepsy Center, University of Erlangen Nuernberg, 91054 Erlangen, Germany
    Acta Neurol Scand 104:195-201. 2001
    ..The new method TISA was used to evaluate Losigamone efficacy...
  23. doi request reprint Pitfalls in diagnosing limbic encephalitis - a case report
    F Kerling
    Epilepsy Center ZEE, Department of Neurology, University of Erlangen Nuremberg, Erlangen, Germany
    Acta Neurol Scand 118:339-42. 2008
    ..The syndrome of limbic encephalitis (LE) is characterized by subacute onset of temporal lobe epilepsy, loss of short-term memory, cognitive confusion and psychiatric symptoms...
  24. ncbi request reprint Short TE single-voxel 1H-MR spectroscopy of hippocampal structures in healthy adults at 1.5 Tesla--how reproducible are the results?
    T Hammen
    Department of Neurology, Epilepsy Center, University of Erlangen Nuremberg, Erlangen Nuremberg, Germany
    NMR Biomed 18:195-201. 2005
    ..857), and Ins (p=0.826). Rescan led to the same results and gave proof of good reproducibility. Scan-rescan testing in one subject showed comparable results: tNAA (CV=4.8%), followed by Cr, Ins, Glu+Gln and Cho (all CV above 10%)...
  25. ncbi request reprint Multimodal coregistration in patients with temporal lobe epilepsy--results of different imaging modalities in lateralization of the affected hemisphere in MR imaging positive and negative subgroups
    M T Doelken
    Department of Neuroradiology, University of Erlangen Nuremberg, Erlangen, Germany
    AJNR Am J Neuroradiol 28:449-54. 2007
    ....
  26. ncbi request reprint Prediction of postoperative outcome with special respect to removal of hemosiderin fringe: a study in patients with cavernous haemangiomas associated with symptomatic epilepsy
    T Hammen
    Department of Neurology, Epilepsy Center, University of Erlangen Nuremberg, Germany
    Seizure 16:248-53. 2007
    ..In this study 30 patients with symptomatic epilepsy caused by cavernomas were investigated in a postoperative follow up study to assess predictors for postoperative outcome with respect to indications, time and approach of surgery...
  27. ncbi request reprint Deficient memory acquisition in temporal lobe epilepsy is predicted by hippocampal granule cell loss
    E Pauli
    Department of Neuropathology, Friedrich Alexander University Erlangen Nuremberg, Erlangen, Germany
    Neurology 67:1383-9. 2006
    ..The hippocampal formation is essentially involved in the formation of conscious memories for facts and events and neurologic diseases affecting the hippocampus associate with severe memory deficits, i.e., temporal lobe epilepsies...
  28. doi request reprint Relation between ictal asystole and cardiac sympathetic dysfunction shown by MIBG-SPECT
    F Kerling
    Epilepsy Center ZEE, Department of Neurology, University Hospital of Erlangen, Erlangen, Germany
    Acta Neurol Scand 120:123-9. 2009
    ..Tachyarrhythmias are common during epileptic seizures while bradyarrhythmias or asystoles are less frequent. Ictal asystole might be related to epilepsy-induced cardiac sympathetic denervation...
  29. ncbi request reprint Identifying the affected hemisphere by (1)H-MR spectroscopy in patients with temporal lobe epilepsy and no pathological findings in high resolution MRI
    T Hammen
    Clinics of Neurology, Epilepsy Center ZEE, University of Erlangen Nuremberg, Erlangen, Germany
    Eur J Neurol 13:482-90. 2006
    ..22+/-0.17*, P=0.035). The results of our study show that (1)H-MRS is able to identify the affected hemisphere of MRI negative TLE patients and can be used as an additive tool in multimodal focus localization...
  30. ncbi request reprint Pain-related somatosensory evoked magnetic fields induced by controlled ballistic mechanical impacts
    K Druschky
    Department of Neurology, University of Erlangen Nuernberg, Germany
    J Clin Neurophysiol 17:613-22. 2000
    ....
  31. ncbi request reprint Etomidate activates epileptic high frequency oscillations
    S Rampp
    Epilepsy Center, Department of Neurology, University Hospital Erlangen, Erlangen, Germany Electronic address
    Clin Neurophysiol 125:223-30. 2014
    ..An HFO inducing effect of etomidate would allow further validation of the substance as a provocation measure in presurgical evaluation as well as provide insights into the common mechanisms of HFO, spike and seizure generation...
  32. ncbi request reprint Spatial intralobar correlation of spike and slow wave activity localisations in focal epilepsies: a MEG analysis
    M Kaltenhäuser
    Epilepsycenter ZEE, Department of Neurology, University of Erlangen Nurnberg, Schwabachanlage 16, D 91054 Erlangen, Germany
    Neuroimage 34:1466-72. 2007
    ..The localisation of slow wave dipole density yielded additional important information and may contribute to defining the irritative zone...
  33. ncbi request reprint Ictal fear in temporal lobe epilepsy: surgical outcome and focal hippocampal changes revealed by proton magnetic resonance spectroscopy imaging
    M Feichtinger
    Department of Neurology, University Erlangen-Nuremberg, Schwabachanlage 6, D-91054 Erlangen, Germany
    Arch Neurol 58:771-7. 2001
    ..In addition, our data emphasize that multivoxel MRS is a valuable tool in the presurgical evaluation, as it may reveal different topographical patterns of hippocampal sclerosis...
  34. ncbi request reprint Comparison of clonidine to sleep deprivation in the potential to induce spike or sharp-wave activity
    B Kettenmann
    Department of Neurology, University of Erlangen Nuremberg, Erlangen, Germany
    Clin Neurophysiol 116:905-12. 2005
    ..This study aimed to investigate previously observed side effects, i.e. increased epileptic activity during clonidine medication. The safety and effectiveness of clonidine as spike inducing agent compared to sleep deprivation were tested...
  35. doi request reprint Detection of epileptic spikes by magnetoencephalography and electroencephalography after sleep deprivation
    M Heers
    Epilepsy Center, Department of Neurology, University Hospital Erlangen, Schwabachanlage 6, D 91054 Erlangen, Germany
    Seizure 19:397-403. 2010
    ....
  36. pmc Magnetoencephalography (MEG) predicts focal epileptogenicity in cavernomas
    H Stefan
    Department of Neurology, Epilepsy and Neuro Center, University of Erlangen Nurnberg, Germany
    J Neurol Neurosurg Psychiatry 75:1309-13. 2004
    ..The aim of this study was to identify the irritative epileptic zone in patients with cavernomas by means of magnetoencephalography (MEG)...
  37. doi request reprint Ictal delusion of sexual transformation
    B S Kasper
    Epilepsy Center, Department of Neurology, Erlangen University, Schwabachanlage 6, 91054 Erlangen, Germany
    Epilepsy Behav 16:356-9. 2009
    ..Here we report about the unique seizure symptom of transformation towards the opposite gender in a patient with a right amygdalar tumor, which we classify as ictal delusional misidentification syndrome...
  38. ncbi request reprint Influence of levetiracetame on ictal and postictal EEG in patients with partial seizures
    C Tilz
    Department of Neurology, Epilepsy Center Erlangen, University of Erlangen Nuremberg, 91054 Erlangen, Germany
    Eur J Neurol 13:1352-8. 2006
    ..03). This study demonstrated that LEV not only prevented the seizure pattern propagation but also helped the speedy recovery of the postictal background activity in the EEG...
  39. ncbi request reprint An efficient, robust and fast method for the offline detection of epileptic seizures in long-term scalp EEG recordings
    R Hopfengärtner
    Epilepsy Center, Department of Neurology, University Hospital Erlangen, Schwabachanlage 6, 91054 Erlangen, Germany
    Clin Neurophysiol 118:2332-43. 2007
    ..It is aimed for seizure detection with high sensitivity and low number of false detections in long-term EEG data without a priori information...
  40. ncbi request reprint Once daily monotherapy with prolonged-release valproate minitablets given in the evening--a chronopharmacological study
    W Graf
    Department of Neurology Epilepsy Center, University Erlangen Nurnberg, Erlangen, Germany
    Int J Clin Pharmacol Ther 47:439-43. 2009
    ..Chronopharmacological investigations concerning efficacy, side effects and circadian serum concentration are lacking for many antiepileptic drugs...
  41. doi request reprint Epilepsy outcomes in elderly treated with topiramate
    H Stefan
    Epilepsy Center, University of Erlangen, Germany
    Acta Neurol Scand 118:164-74. 2008
    ..To explore effectiveness, tolerability and quality of life in elderly patients with epilepsy treated with topiramate...
  42. ncbi request reprint Changes of seizures activity during rapid withdrawal of lamotrigine
    Y Wang-Tilz
    Department of Neurology, Center of Epilepsy ZEE, University of Erlangen Nuremberg, Erlangen, Germany
    Eur J Neurol 12:280-8. 2005
    ..This study justified the withdrawal in pre-surgical localization, rationalized precautions for possible accompanying risks, and also aroused attentions in clinical anticonvulsant trials and substitutions involving withdrawal process...
  43. ncbi request reprint Fractionated stereotactically guided radiotherapy of pharmacoresistant temporal lobe epilepsy
    G G Grabenbauer
    Department of Radiation Therapy, Friedrich Alexander University of Erlangen Nurnberg, Erlangen, Germany
    Acta Neurochir Suppl 84:65-70. 2002
    ..This prospective study evaluated the efficacy of fractionated stereotactically guided radiotherapy (SRT) as a treatment of pharmacoresistant temporal lobe epilepsy...
  44. ncbi request reprint Interictal cardiac autonomic dysfunction in temporal lobe epilepsy demonstrated by [(123)I]metaiodobenzylguanidine-SPECT
    A Druschky
    Department of Neurology, University of Erlangen-Nuremberg, Germany
    Brain 124:2372-82. 2001
    ..MIBG-SPECT demonstrates altered post-ganglionic cardiac sympathetic innervation. This dysfunction might carry an increased risk of cardiac abnormalities...
  45. ncbi request reprint A new approach in anti-epileptic drug evaluation
    H Stefan
    Department of Neurology, Epilepsy Center ZEE, University of Erlangen Nurnberg, Erlangen, Germany
    Eur J Neurol 11:467-73. 2004
    ..In addition long-term effects can be evaluated by repeated video-EEG monitoring...
  46. ncbi request reprint Cavernous haemangiomas, epilepsy and treatment strategies
    H Stefan
    Department of Neurology, Epilepsy Center Erlangen ZEE, University Erlangen Nuernberg, Erlangen, Germany
    Acta Neurol Scand 110:393-7. 2004
    ..To achieve optimal treatment of patients with cavernous haemangiomas and epilepsy both medical and surgical treatment have to be considered...
  47. ncbi request reprint [Goose flesh and cold sensation. Symptoms of visceral epilepsy]
    H Stefan
    Neurologische Klinik Zentrum Epilepsie Universität Erlangen Nürnberg, Schwabachanlage 6, 91054 Erlangen
    Nervenarzt 73:188-93. 2002
    ..Interestingly, patients did not suffer from tumoral epilepsies and the epileptic focus was lateralized to the left (dominant) temporal lobe...
  48. ncbi request reprint Novel anticonvulsant drugs
    H Stefan
    University Clinic Erlangen, Epilepsy Center Neurological Department, Schwabachanlage 6, D 91054 Erlangen, Germany
    Pharmacol Ther 113:165-83. 2007
    ..New anticonvulsant drugs increase the spectrum of treatment and represent further steps with regard to the optimization of an individual therapy of the epilepsies...
  49. doi request reprint Phenomenology of hallucinations, illusions, and delusions as part of seizure semiology
    B S Kasper
    Epilepsy Center, Department of Neurology, Friedrich Alexander University, Schwabachanlage 6, Erlangen, Germany
    Epilepsy Behav 18:13-23. 2010
    ..This article, in which 10 cases are described, introduces the fascinating phenomenology of subjective seizure symptoms...
  50. ncbi request reprint Ictal onset localization of epileptic seizures by magnetoencephalography
    C Tilz
    Department of Neurology, Epilepsy Center, Friedrich Alexander University of Erlangen Nuernberg, Germany
    Acta Neurol Scand 106:190-5. 2002
    ....
  51. ncbi request reprint 1H-MR spectroscopy: a promising method in distinguishing subgroups in temporal lobe epilepsy?
    Th Hammen
    Department of Neurology, Center Epilepsy, Neurologische Klinik mit Poliklinik, University Erlangen Nurnberg, ZEE Zentrum Epilepsie Erlangen Schwabachanlage 6, D 91054 Erlangen, Germany
    J Neurol Sci 215:21-5. 2003
    ..Our results reveal that 1H-MRS is able to distinguish between mesiobasal and lateral pathologies in patients with TLE and represents a useful tool for noninvasive TLE classification...
  52. doi request reprint [Emotional and affective disorders, anxiety and personality disorders in epilepsies]
    E Pauli
    Epilepsiezentrum Neurologische Klinik, Universitatsklinikum, Schwabachanlage 6, Erlangen, Germany
    Nervenarzt 80:1440-51. 2009
    ..Newly diagnosed mental problems are rarely reported after surgery; more often positive changes are observed across the entire spectrum of mental disorders associated with epilepsy...
  53. ncbi request reprint Progressive cognitive decline in epilepsy: an indication of ongoing plasticity
    H Stefan
    Department of Neurology, Epilepsy Center University Erlangen Nürnberg, Schwabachanlage 6, 91054 Erlangen, Germany
    Prog Brain Res 135:409-17. 2002
    ..Concepts for memory storage and consolidation and mechanisms of plasticity concerning epileptic activity as well as modification of long-term potentiation for plasticity with regard to memory functions are also discussed...
  54. ncbi request reprint Somatosensory evoked magnetic fields following passive movement compared with tactile stimulation of the index finger
    K Druschky
    Department of Neurology, University of Erlangen Nurnberg, Schwabachanlage 6, 91054 Erlangen, Germany
    Exp Brain Res 148:186-95. 2003
    ....
  55. pmc Sex differences and lateral asymmetry in heart rate modulation in patients with temporal lobe epilepsy
    A Kirchner
    Department of Neurology, University of Erlangen Nuremberg, Erlangen, Germany
    J Neurol Neurosurg Psychiatry 73:73-5. 2002
    ..24, df = 2.58/27, p < 0.001). These results confirm the right hemispheric lateralisation of sympathetic cardiac control in male patients...
  56. ncbi request reprint Emerging drugs for epilepsy and other treatment options
    H Stefan
    Epilepsy Center ZEE Neurological Clinic, University Erlangen Nuernberg, Schwabachanlage, Erlangen, Germany
    Eur J Neurol 14:1154-61. 2007
    ..The aim of this review is to highlight currently emerging different treatment approaches which may ameliorate the perspectives of patients with difficult-to-treat epilepsies...
  57. ncbi request reprint Epileptogenesis and rational therapeutic strategies
    H Stefan
    Epilepsy Centre Neurological Clinic, University Erlangen Nuernberg, Erlangen, Germany
    Acta Neurol Scand 113:139-55. 2006
    ....
  58. ncbi request reprint [Emotional and affective disorders in epilepsy]
    E Pauli
    Epilepsiezentrum Neurologische Klinik, Universitatsklinikum Erlangen, Schwabachanlage 6, 91054, Erlangen, Deutschland
    Nervenarzt 80:729-44. 2009
    ..Although established as a successful treatment option for focal epilepsies, surgery is also reported to influence mental health...
  59. ncbi request reprint Clinical applications of 1H-MR spectroscopy in the evaluation of epilepsies--what do pathological spectra stand for with regard to current results and what answers do they give to common clinical questions concerning the treatment of epilepsies?
    T Hammen
    Clinics of Neurology, Center Epilepsy, University of Erlangen Nuremberg, Erlangen, Germany
    Acta Neurol Scand 108:223-38. 2003
    ..In the following article, the principles of 1H-MRS and an overview of it in the evaluation and treatment of epilepsies with special regard to temporal lobe epilepsies (TLE) has been illustrated...
  60. ncbi request reprint Serum prolactin concentrations and epilepsy. A study which compares healthy subjects with a group of patients in presurgical evaluation and circadian variations with those related to seizures
    J Bauer
    Department of Neurology, , Federal Republic of Germany
    Eur Arch Psychiatry Clin Neurosci 241:365-71. 1992
    ..As a trend, in the period preceding an epileptic seizure we found a slightly decreasing PRL level, whereas in healthy persons the PRL concentrations gradually increased in the 40 minutes before the maximum spontaneous peak was reached...
  61. ncbi request reprint [How to diagnose and treat epilepsy]
    H Stefan
    Epilepsiezentrum Universität Erlangen Nürnberg, Erlangen
    MMW Fortschr Med 146:41-4, 46. 2004
    ..Difficult-to-treat and drug-resistant epilepsy should be treated surgically and the patients should be referred to an epilepsy center for a pre-operative diagnostic work-up...
  62. ncbi request reprint [(1)H MR spectroscopy. Methods and applications in diagnosis and assessment of surgical and conservative treatment strategies in epilepsies]
    T Hammen
    Neurologische Klinik mit Poliklinik, Zentrum Epilepsie, Universitat Erlangen Nurnberg, Erlangen
    Nervenarzt 75:970-83. 2004
    ..Additionally the application of (1)H-MRS for evaluating postoperative outcome and monitoring conservative antiepileptic treatment schedules is summarized...
  63. ncbi request reprint [Is epilepsy in the elderly overlooked? An investigation in a home for the aged]
    A Flierl-Hecht
    Zentrum Epilepsie Erlangen, Neurologische Universitätsklinik Erlangen
    Nervenarzt 74:691-8. 2003
    ..The results of our pilot study suggest that epilepsy in old people's homes is often unrecognised. Early diagnosis and treatment of epilepsy in the elderly is important to improve prognosis and social consequences for affected persons...
  64. ncbi request reprint [Diagnostic imaging in refractory temporal lobe epilepsy. A comparison of MR volumetry and multivoxel-MR-spectroscopy for assessment of postoperative prognosis]
    H Stefan
    Neurologische Klinik,
    Nervenarzt 72:130-5. 2001
    ..In case of bilateral changes, the severity of metabolic changes in the nonoperated, contralateral side was decisive for postoperative outcome. The results from volumetry did not correlate with postoperative outcome...
  65. ncbi request reprint Suicidal attempts and aggressive behaviours after temporal lobectomy in epilepsy
    T Hillemacher
    Eur J Neurol 14:e10. 2007
  66. ncbi request reprint Autonomic auras: left hemispheric predominance of epileptic generators of cold shivers and goose bumps?
    H Stefan
    Department of Neurology Center Epilepsy, University of Erlangen Nurnberg, Germany
    Epilepsia 43:41-5. 2002
    ..Autonomic seizures in temporal lobe epilepsies associated with "cold shivers and goose bumps" as a principal ictal sign or aura have only rarely been studied...
  67. ncbi request reprint [Diagnosis of sylvian and perisylvian epilepsies. Excitation symptomes of the insula reilii]
    H Stefan
    Epilepsiezentrum Erlangen ZEE Neurologische Klinik, Universitatsklinikum, Erlangen
    Nervenarzt 78:1175-81. 2007
    ..Magnetic source imaging as noninvasive treatment can deliver important information for the involvement of sylvian and perisylvian regions in focal pharmacoresistant epilepsies...
  68. ncbi request reprint [Pharmacological treatment of epilepsies: progress during the last 10 years]
    H Stefan
    Neurologische Klinik, Universitat Erlangen Nurnberg, Erlangen
    Fortschr Neurol Psychiatr 70:339-52. 2002
    ..Pharmacology, pharmacocinetics, indication, dosage and side effects of the substances will be summarized and discussed...
  69. ncbi request reprint Influence of vagus nerve stimulation on histamine-induced itching
    A Kirchner
    Neurologische Klinik, Friedrich Alexander Universität Erlangen, Germany
    Neurology 59:108-12. 2002
    ..To investigate whether vagus nerve stimulation (VNS) reduces pruritus in humans...
  70. ncbi request reprint Visual field defect during therapy with valproic-acid
    C Tilz
    Department of Neurology 1, Krankenhaus Barmherzige Brüder Linz, Austria
    Eur J Neurol 14:929-32. 2007
    ..In conclusion, the concentric visual field defect related to VPA treatment is rare but possible...
  71. ncbi request reprint [Supratentorial cavernoma and epileptic seizures. Are there predictors for postoperative seizure control?]
    H Stefan
    Neurologische Klinik Zentrum Epilepsie ZEE, Universitat Erlangen Nurnberg, Erlangen
    Nervenarzt 75:755-62. 2004
    ..None of the four patients harbouring multiple cavernomas became seizure-free after resection of one lesion, which was believed to be mostly attributable to the epileptic focus that was removed...
  72. ncbi request reprint Ictal dystonic posturing in mesial versus neocortical temporal lobe seizures
    A Holl
    Department of Neurology, Medical University of Graz, Auenbruggerplatz 22, 8036 Graz, Austria
    Seizure 14:269-73. 2005
    ....
  73. ncbi request reprint [Brain tumors and epilepsy]
    H Stefan
    Neurologische Klinik, Epilepsiezentrum ZEE, Erlangen
    Nervenarzt 76:1196, 1198-200, 1203-4, 1206-8. 2005
    ..These should consider possibilities of new techniques of co-registering imaging and electrophysiology, surgery, and the interaction of anticonvulsive and chemotherapeutic drugs, cognition, and mood...
  74. ncbi request reprint [Valproate sustained release in the treatment of epilepsy]
    H Stefan
    Epilepsiezentrum der Neurologischen Klinik der Universität Erlangen
    Fortschr Neurol Psychiatr 73:681-6. 2005
    ..These results confirm the excellent benefit-risk ratio of the valproate sustained release minitablets and underline the importance of a simple compliance-improving dose regimen for effective seizure control...
  75. ncbi request reprint [Ictal signs--cerebral localization and propagation]
    H Stefan
    Neurologische Klinik, Zentrum Epilepsie der Universität Erlangen Nuremberg, Erlangen
    Nervenarzt 74:527-35; quiz 536. 2003
    ..Limitations of so-called silent brain regions in this respect are also discussed. As a simple aid for clinical diagnosis, the nuclear shell structure model is demonstrated...
  76. ncbi request reprint Fast activity as a surrogate marker of epileptic network function?
    S Rampp
    Epilepsy Center Erlangen, University of Erlangen Nuremberg, Germany
    Clin Neurophysiol 117:2111-7. 2006
    ..In this review, an overview of the electrophysiologic characteristics, putative cellular and network mechanisms in epilepsy is given. Recent studies are reviewed and interpreted in the context of a common hypothetical model...