Research Topics
Genomes and GenesSpecies | Ralf StanewskySummaryAffiliation: University of Regensburg Country: Germany Publications
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Detail Information
Publications
Clock mechanisms in DrosophilaRalf Stanewsky
Universitat Regensburg, Institut fur Zoologie, Lehrstuhl für Entwicklungsbiologie, Universitatsstrasse 31, 93040 Regensburg, Germany
Cell Tissue Res 309:11-26. 2002..Although their regulation depends on the major clock genes, the majority of the clock-controlled genes are not direct targets of clock factors...
Mapping of elements involved in regulating normal temporal period and timeless RNA expression patterns in Drosophila melanogasterRalf Stanewsky
Zoologisches Institut, Entwicklungsbiologie, Universitat Regensburg, Germany
J Biol Rhythms 17:293-306. 2002..The results establish that, for normal rhythmicity, expression of clock genes requires regulation at the transcriptional, posttranscriptional, and posttranslational levels...
Genetic analysis of the circadian system in Drosophila melanogaster and mammalsRalf Stanewsky
Universitat Regensburg, Institut fur Zoologie, Lehrstuhl für Entwicklungsbiologie, Universitatsstrasse 31, 93040 Regensburg, Germany
J Neurobiol 54:111-47. 2003..This review will try to give a comparative overview about the two systems, highlighting similarities as well as specifics of both insect and murine clocks...
The neuropeptide pigment-dispersing factor adjusts period and phase of Drosophila's clockTaishi Yoshii
Institute of Zoology, University of Regensburg, 93040 Regensburg, Germany
J Neurosci 29:2597-610. 2009..Under natural conditions PDF may be required for adapting Drosophila's clock to varying photoperiods. Indeed, we show here that Pdf(01) mutants are not able to adapt their activity to long photoperiods in a wild-type manner...
Cryptochrome is present in the compound eyes and a subset of Drosophila's clock neuronsTaishi Yoshii
Institute of Zoology, University of Regensburg, 93040 Regensburg, Germany
J Comp Neurol 508:952-66. 2008....
A self-sustaining, light-entrainable circadian oscillator in the Drosophila brainShobi Veleri
Universitat Regensburg, Institut fur Zoologie, Lehrstuhl für Entwicklungsbiologie, 93040, Regensburg, Germany
Curr Biol 13:1758-67. 2003..Here we restricted expression of a novel period-luciferase transgene to certain clock neurons in the Drosophila brain, permitting us to monitor reporter gene activity in these cells in real-time...
The novel Drosophila tim(blind) mutation affects behavioral rhythms but not periodic eclosionCorinna Wülbeck
Universitat Regensburg, Institut fur Zoologie, Lehrstuhl für Entwicklungsbiologie, 93040 Regensburg, Germany
Genetics 169:751-66. 2005..Therefore it seems possible that TIM--in addition to its well-established role as core clock factor--functions as a clock output factor, involved in determining the period length of adult locomotor rhythms...
Cryptochrome, compound eyes, Hofbauer-Buchner eyelets, and ocelli play different roles in the entrainment and masking pathway of the locomotor activity rhythm in the fruit fly Drosophila melanogasterDirk Rieger
University of Regensburg, Institute of Zoology, 93040 Regensburg, Germany
J Biol Rhythms 18:377-91. 2003..The specific roles of the remaining photoreceptors are more difficult to assess...
Veela defines a molecular link between Cryptochrome and Timeless in the light-input pathway to Drosophila's circadian clockNicolai Peschel
Institute of Zoology, University of Regensburg, Universitatsstrasse 31, 93040 Regensburg, Germany
Proc Natl Acad Sci U S A 103:17313-8. 2006....
Temperature synchronization of the Drosophila circadian clockFranz T Glaser
Institut fur Zoologie, Universitat Regensburg, 93040 Regensburg, Germany
Curr Biol 15:1352-63. 2005..Although it has long been known that temperature cycles can robustly entrain Drosophila locomotor rhythms, nothing is known about the molecular mechanisms involved...
A role for the PERIOD:PERIOD homodimer in the Drosophila circadian clockJohannes Landskron
Institut fur Zoologie, Universitat Regensburg, Regensburg, Germany
PLoS Biol 7:e3. 2009..Our results confirm a previous structural model for PER and provide strong evidence that PER homodimers are important for circadian clock function...
Identification of circadian-clock-regulated enhancers and genes of Drosophila melanogaster by transposon mobilization and luciferase reporting of cyclical gene expressionThomas Stempfl
, , , 93040 Regensburg, Germany
Genetics 160:571-93. 2002..In addition to its known role in cell fate determination, this gene and the phosphotyrosine-binding protein it encodes are likely to function in the circadian system...
Hofbauer-Buchner eyelet affects circadian photosensitivity and coordinates TIM and PER expression in Drosophila clock neuronsShobi Veleri
Institute of Zoology, Regensburg, Germany
J Biol Rhythms 22:29-42. 2007....
Analysis of rhythmic gene expression in adult Drosophila using the firefly luciferase reporter geneRalf Stanewsky
School of Biological and Chemical Sciences, Queen Mary University of London, UK
Methods Mol Biol 362:131-42. 2007..This chapter describes how rhythmic expression of clock or clock-controlled genes can be measured in living adult Drosophila. A survey of all existing clock-related luciferase transgenics is given...
A molecular basis for natural selection at the timeless locus in Drosophila melanogasterFederica Sandrelli
Department of Biology, University of Padova, 35131 Padova, Italy
Science 316:1898-900. 2007..This interaction results in a more stable TIMELESS product. These findings reveal a molecular link between diapause and circadian photoreception...
Function of the Shaw potassium channel within the Drosophila circadian clockJames J Hodge
Department of Physiology and Pharmacology, School of Medical Sciences, Bristol University, Bristol, United Kingdom
PLoS ONE 3:e2274. 2008....
The extraretinal eyelet of Drosophila: development, ultrastructure, and putative circadian functionCharlotte Helfrich-Förster
Zoological Institute Animal Physiology, University of Tubingen, D 72076 Tubingen, Germany
J Neurosci 22:9255-66. 2002..Thus a functional role in circadian entrainment first found in Bolwig's organ in the larva is retained in eyelet, the adult remnant of Bolwig's organ, even in the face of metamorphic restructuring...
Drosophila CRYPTOCHROME is a circadian transcriptional repressorBen Collins
Department of Biology, New York University, 100 Washington Square East, New York, New York 10003, USA
Curr Biol 16:441-9. 2006....
