Kai Spiegelhalder

Summary

Affiliation: University Hospital
Country: Germany

Publications

  1. doi request reprint Does REM sleep contribute to subjective wake time in primary insomnia? A comparison of polysomnographic and subjective sleep in 100 patients
    Bernd Feige
    Department of Psychiatry and Psychotherapy, University Medical Center, Freiburg, Germany
    J Sleep Res 17:180-90. 2008
  2. doi request reprint Sleep-related attentional bias in patients with primary insomnia compared with sleep experts and healthy controls
    Kai Spiegelhalder
    Department of Psychiatry and Psychotherapy, University of Freiburg Medical Center, Freiburg, Germany
    J Sleep Res 17:191-6. 2008
  3. doi request reprint Sleep and emotions: a focus on insomnia
    Chiara Baglioni
    Department of Psychiatry and Psychotherapy, University of Freiburg Medical Center, Hauptstrasse 5, 79104 Freiburg, Germany
    Sleep Med Rev 14:227-38. 2010
  4. pmc The association between insomnia and cardiovascular diseases
    Kai Spiegelhalder
    Department of Psychiatry and Psychotherapy, University of Freiburg Medical Center, Freiburg, Germany
    Nat Sci Sleep 2:71-8. 2010
  5. doi request reprint Interindividual synchronization of brain activity during live verbal communication
    Kai Spiegelhalder
    Department of Psychiatry and Psychotherapy, University of Freiburg Medical Center, Hauptstraße 5, 79104 Freiburg, Germany Electronic address
    Behav Brain Res 258:75-9. 2014
  6. doi request reprint Neuroimaging studies in insomnia
    Kai Spiegelhalder
    Department of Psychiatry and Psychotherapy, University of Freiburg Medical Center, Hauptstraße 5, 79104, Freiburg, Germany
    Curr Psychiatry Rep 15:405. 2013
  7. pmc Insomnia does not appear to be associated with substantial structural brain changes
    Kai Spiegelhalder
    Department of Psychiatry and Psychotherapy, University Medical Center Freiburg, Germany
    Sleep 36:731-7. 2013
  8. doi request reprint Comorbid sleep disorders in neuropsychiatric disorders across the life cycle
    Kai Spiegelhalder
    Department of Psychiatry and Psychotherapy, University of Freiburg Medical Center, Hauptstraße 5, 79104, Freiburg, Germany
    Curr Psychiatry Rep 15:364. 2013
  9. doi request reprint Increased EEG sigma and beta power during NREM sleep in primary insomnia
    Kai Spiegelhalder
    Department of Psychiatry and Psychotherapy, University of Freiburg Medical Center, Germany
    Biol Psychol 91:329-33. 2012
  10. pmc Sleep-related arousal versus general cognitive arousal in primary insomnia
    Kai Spiegelhalder
    Department of Psychiatry and Psychotherapy, University of Freiburg Medical Center, Hauptstraße 5, Freiburg, Germany
    J Clin Sleep Med 8:431-7. 2012

Detail Information

Publications32

  1. doi request reprint Does REM sleep contribute to subjective wake time in primary insomnia? A comparison of polysomnographic and subjective sleep in 100 patients
    Bernd Feige
    Department of Psychiatry and Psychotherapy, University Medical Center, Freiburg, Germany
    J Sleep Res 17:180-90. 2008
    ..This REM sleep contribution was larger for PI than for GSC subjects. The findings suggest that REM sleep-related processes might contribute to subjectively disturbed sleep and the perception of waking time in patients with PI...
  2. doi request reprint Sleep-related attentional bias in patients with primary insomnia compared with sleep experts and healthy controls
    Kai Spiegelhalder
    Department of Psychiatry and Psychotherapy, University of Freiburg Medical Center, Freiburg, Germany
    J Sleep Res 17:191-6. 2008
    ..The findings suggest that a desensitization of sleep-related stimuli might be used therapeutically, thus extending the current cognitive behavioral treatments for primary insomnia...
  3. doi request reprint Sleep and emotions: a focus on insomnia
    Chiara Baglioni
    Department of Psychiatry and Psychotherapy, University of Freiburg Medical Center, Hauptstrasse 5, 79104 Freiburg, Germany
    Sleep Med Rev 14:227-38. 2010
    ..Good sleep seems to be associated with high positive emotions, but not necessarily with low negative emotions. This review underlines the need for future research on emotions in insomnia...
  4. pmc The association between insomnia and cardiovascular diseases
    Kai Spiegelhalder
    Department of Psychiatry and Psychotherapy, University of Freiburg Medical Center, Freiburg, Germany
    Nat Sci Sleep 2:71-8. 2010
    ..Consequently, more effort should be dedicated to cope with the high prevalence of insomnia in the general population...
  5. doi request reprint Interindividual synchronization of brain activity during live verbal communication
    Kai Spiegelhalder
    Department of Psychiatry and Psychotherapy, University of Freiburg Medical Center, Hauptstraße 5, 79104 Freiburg, Germany Electronic address
    Behav Brain Res 258:75-9. 2014
    ..In particular, it may serve to study the process of psychotherapy on a neuronal level. ..
  6. doi request reprint Neuroimaging studies in insomnia
    Kai Spiegelhalder
    Department of Psychiatry and Psychotherapy, University of Freiburg Medical Center, Hauptstraße 5, 79104, Freiburg, Germany
    Curr Psychiatry Rep 15:405. 2013
    ..Future investigations should include larger sample sizes or longitudinal within-subject comparisons. Other possible methodological improvements are discussed. ..
  7. pmc Insomnia does not appear to be associated with substantial structural brain changes
    Kai Spiegelhalder
    Department of Psychiatry and Psychotherapy, University Medical Center Freiburg, Germany
    Sleep 36:731-7. 2013
    ..The goal of the current study was to investigate brain morphometry in a well-characterized large sample of patients with primary insomnia (PI) in comparison with good sleeper controls...
  8. doi request reprint Comorbid sleep disorders in neuropsychiatric disorders across the life cycle
    Kai Spiegelhalder
    Department of Psychiatry and Psychotherapy, University of Freiburg Medical Center, Hauptstraße 5, 79104, Freiburg, Germany
    Curr Psychiatry Rep 15:364. 2013
    ..Whether adequate treatment of sleep disorders can prevent the incidence of psychiatric disorders, remains to be investigated...
  9. doi request reprint Increased EEG sigma and beta power during NREM sleep in primary insomnia
    Kai Spiegelhalder
    Department of Psychiatry and Psychotherapy, University of Freiburg Medical Center, Germany
    Biol Psychol 91:329-33. 2012
    ....
  10. pmc Sleep-related arousal versus general cognitive arousal in primary insomnia
    Kai Spiegelhalder
    Department of Psychiatry and Psychotherapy, University of Freiburg Medical Center, Hauptstraße 5, Freiburg, Germany
    J Clin Sleep Med 8:431-7. 2012
    ..The present study aimed at further investigating trait aspects of sleep-related cognitive arousal and general cognitive arousal and their association with both objective and subjective sleep parameters in primary insomnia patients...
  11. doi request reprint Time will tell: a retrospective study investigating the relationship between insomnia and objectively defined punctuality
    Kai Spiegelhalder
    Department of Psychiatry and Psychotherapy, University of Freiburg Medical Center, Freiburg, Germany
    J Sleep Res 21:264-9. 2012
    ..Clinical implications of the current results for cognitive behavioural treatments of insomnia are discussed...
  12. doi request reprint Heart rate and heart rate variability in subjectively reported insomnia
    Kai Spiegelhalder
    Department of Psychiatry and Psychotherapy, University of Freiburg Medical Center, Freiburg, Germany
    J Sleep Res 20:137-45. 2011
    ..A lower wake-to-sleep HR reduction and alterations in HRV variables might, at least partially, mediate the increased rates of cardiovascular morbidity and mortality observed in insomnia patients...
  13. doi request reprint Is smoking-related attentional bias a useful marker for treatment effects?
    Kai Spiegelhalder
    University of Freiburg Medical Center, Department of Psychiatry and Psychotherapy, Freiburg, Germany
    Behav Med 37:26-34. 2011
    ..Additionally, there was no significant correlation between the attentional bias scores from both tasks...
  14. pmc The impact of sleep-related attentional bias on polysomnographically measured sleep in primary insomnia
    Kai Spiegelhalder
    University of Freiburg Medical Center, Department of Psychiatry and Psychotherapy, Freiburg, Germany
    Sleep 33:107-12. 2010
    ..Although sleep-related attentional bias has been shown to be evident in primary insomnia, the association with objectively measured sleep has not been investigated. In the present study, we used polysomnography (PSG) to fill this void...
  15. doi request reprint Cerebral correlates of heart rate variations during a spontaneous panic attack in the fMRI scanner
    Kai Spiegelhalder
    Department of Psychiatry and Psychotherapy, University of Freiburg Medical Center, Hauptstrasse 5, 79104 Freiburg, Germany
    Neurocase 15:527-34. 2009
    ..Additionally, regions-of-interest (ROI) analyses indicated significant positive associations in the left amygdala, and trends towards significance in the right amygdala and left insula...
  16. doi request reprint The effect of sleep-specific brain activity versus reduced stimulus interference on declarative memory consolidation
    Hannah Piosczyk
    Department of Psychiatry and Psychotherapy, University Medical Center Freiburg, Freiburg, Germany
    J Sleep Res 22:406-13. 2013
    ....
  17. doi request reprint Sleep-related memory consolidation in primary insomnia
    Christoph Nissen
    Department of Psychiatry and Psychotherapy, University Medical Center Freiburg, Freiburg, Germany
    J Sleep Res 20:129-36. 2011
    ..Future work is needed to investigate the impact of treatment on improving sleep and memory...
  18. doi request reprint EEG Σ and slow-wave activity during NREM sleep correlate with overnight declarative and procedural memory consolidation
    Johannes Holz
    Department of Psychiatry and Psychotherapy, University Medical Center Freiburg, Freiburg, Germany
    J Sleep Res 21:612-9. 2012
    ....
  19. doi request reprint The microstructure of sleep in primary insomnia: an overview and extension
    Bernd Feige
    Department of Psychiatry and Psychotherapy, Freiburg University Medical Center, Hauptstraße 5, 79104 Freiburg, Germany Electronic address
    Int J Psychophysiol 89:171-80. 2013
    ..An overview of the relevant empirical evidence is presented, previous investigations are extended and a theoretical synthesis within the framework of the hyperarousal concept of insomnia is attempted. ..
  20. doi request reprint The hyperarousal model of insomnia: a review of the concept and its evidence
    Dieter Riemann
    Department of Psychiatry and Psychotherapy, Freiburg University Medical Center, Hauptstrasse 5, D 79104 Freiburg, Germany
    Sleep Med Rev 14:19-31. 2010
    ....
  21. doi request reprint Quantitative measurement of sleep quality using cardiopulmonary coupling analysis: a retrospective comparison of individuals with and without primary insomnia
    Preetam J Schramm
    Research Division, AWP Freiburg, Immental Str 11, 79104 Freiburg, Germany
    Sleep Breath 17:713-21. 2013
    ..The purpose of this study was to determine the utility of a new operator-independent, automated measure of sleep physiology based on cardiopulmonary coupling (CPC) analysis in subjects with primary insomnia vs. good sleepers...
  22. pmc The timing of learning before night-time sleep differentially affects declarative and procedural long-term memory consolidation in adolescents
    Johannes Holz
    Department of Psychiatry and Psychotherapy, University Medical Center Freiburg, Freiburg, Germany
    PLoS ONE 7:e40963. 2012
    ..In contrast, the higher retention of declarative memories after encoding in the afternoon is surprising, appeared to be less robust and needs further investigation...
  23. doi request reprint Insomnia as a predictor of depression: a meta-analytic evaluation of longitudinal epidemiological studies
    Chiara Baglioni
    Department of Psychiatry and Psychotherapy, University of Freiburg Medical Center, Hauptstrasse 5, 79104 Freiburg, Germany
    J Affect Disord 135:10-9. 2011
    ..This meta-analysis is aimed at evaluating quantitatively if insomnia constitutes a predictor of depression...
  24. ncbi request reprint Cerebral correlates of muscle tone fluctuations in restless legs syndrome: a pilot study with combined functional magnetic resonance imaging and anterior tibial muscle electromyography
    Kai Spiegelhalder
    Department of Psychiatry and Psychotherapy, University Hospital, Hauptstrasse 5, 79104 Freiburg, Germany
    Sleep Med 9:177-83. 2008
    ..To investigate the pathomechanism of the disorder further we recorded a surface electromyogram (EMG) of the anterior tibial muscle during functional magnetic resonance imaging (fMRI) in patients with idiopathic RLS...
  25. ncbi request reprint Voxel-based morphometry in unmedicated patients with restless legs syndrome
    Magdolna Hornyak
    Center for Sleep Research and Sleep Medicine, Department of Psychiatry and Psychotherapy, University Hospital, Freiburg, Germany
    Sleep Med 9:22-6. 2007
    ..To address this issue, we performed VBM in unmedicated RLS patients...
  26. ncbi request reprint Restless legs syndrome in older adults
    Kai Spiegelhalder
    Sleep Disorders Center, Department of Psychiatry and Psychotherapy, University Hospital Freiburg, Hauptstrasse 5, D 79104 Freiburg, Germany
    Clin Geriatr Med 24:167-80, ix. 2008
    ..Secondary forms of RLS and possible interaction with other medications require particular consideration in the elderly...
  27. doi request reprint Predictability of alcohol relapse by hippocampal volumetry and psychometric variables
    Claus M Gross
    University of Freiburg Medical Center, Department of Psychiatry and Psychotherapy, Hauptstraße 5, Freiburg 79104, Germany
    Psychiatry Res 212:14-8. 2013
    ..Further studies are required to identify crucial factors which are responsible for successful or unsuccessful relapse prevention...
  28. ncbi request reprint The impact of acamprosate on cue reactivity in alcohol dependent individuals: a functional magnetic resonance imaging study
    Jens M Langosch
    Department of Psychiatry and Psychotherapy, University of Freiburg Medical Center, Freiburg, Germany
    J Clin Psychopharmacol 32:661-5. 2012
    ..However, in comparison with psychiatric inpatient treatment alone, there was no additional effect of acamprosate on cue-related brain activity...
  29. pmc Chronic insomnia and MRI-measured hippocampal volumes: a pilot study
    Dieter Riemann
    Department of Psychiatry and Psychotherapy, Freiburg University Medical Center, Hauptstr 5, D 79104 Germany
    Sleep 30:955-8. 2007
    ..Morphometric analysis of magnetic resonance imaging brain scans was used to investigate possible neuroanatomic differences between patients with primary insomnia compared to good sleepers...
  30. doi request reprint Impact of alcohol-related video sequences on functional MRI in abstinent alcoholics
    Ute J Krienke
    Department of Psychiatry and Psychotherapy, University of Freiburg Medical Center, Freiburg, Germany
    Eur Addict Res 20:33-40. 2014
    ..The involvement of these regions in processes of memory, self-control, and self-reflection with a particular focus on alcohol dependence and craving will be discussed. ..
  31. pmc Management of insomnia: update and new approaches
    Thomas Unbehaun
    Department of Psychiatry and Psychotherapy, University of Freiburg Medical Center, Freiburg, Germany
    Nat Sci Sleep 2:127-38. 2010
    ..Randomized controlled studies are needed to evaluate the efficacy of this and other new approaches to treat insomnia...
  32. pmc Clinical implications of the causal relationship between insomnia and depression: how individually tailored treatment of sleeping difficulties could prevent the onset of depression
    Chiara Baglioni
    Department of Psychiatry and Psychotherapy, University of Freiburg Medical Center, Hauptstraße 5, 79104 Freiburg, Germany
    EPMA J 2:287-93. 2011
    ....