Markus Sperandio

Summary

Affiliation: University of Munich
Country: Germany

Publications

  1. pmc Ontogenetic regulation of leukocyte recruitment in mouse yolk sac vessels
    Markus Sperandio
    Walter Brendel Center of Experimental Medicine, Ludwig Maximilians Universitat, Munich, Germany
    Blood 121:e118-28. 2013
  2. doi request reprint Neutrophil and endothelial adhesive function during human fetal ontogeny
    Claudia Nussbaum
    1 Ludwig Maximilians Universität, Marchioninistr 27, 81377 Munich, Germany Twitter http www twitter com www sfb914 de
    J Leukoc Biol 93:175-84. 2013
  3. doi request reprint The expanding role of α2-3 sialylation for leukocyte trafficking in vivo
    Markus Sperandio
    Walter Brendel Center of Experimental Medicine, Ludwig Maximilians Universitat, Munich, Germany
    Ann N Y Acad Sci 1253:201-5. 2012
  4. pmc RAGE and ICAM-1 differentially control leukocyte recruitment during acute inflammation in a stimulus-dependent manner
    David Frommhold
    Department of Neonatology, University of Heidelberg, 20 Heidelberg, Germany
    BMC Immunol 12:56. 2011
  5. pmc Spleen tyrosine kinase Syk is critical for sustained leukocyte adhesion during inflammation in vivo
    David Frommhold
    Children s Hospital, Neonatal Unit, University of Heidelberg, Germany
    BMC Immunol 8:31. 2007
  6. pmc Glycosylation in immune cell trafficking
    Markus Sperandio
    Walter Brendel Center of Experimental Medicine, Ludwig Maximilians Universitat, Munich, Germany
    Immunol Rev 230:97-113. 2009
  7. doi request reprint Hematopoietic progenitor kinase 1 (HPK1) is required for LFA-1-mediated neutrophil recruitment during the acute inflammatory response
    Sascha M Jakob
    Walter Brendel Centre of Experimental Medicine, Ludwig Maximilians Universitat, Munich, Germany
    Blood 121:4184-94. 2013
  8. doi request reprint Innate immune cell recruitment in the fetus and neonate
    Claudia Nussbaum
    Walter Brendel Center of Experimental Medicine, Ludwig Maximilians Universitat, Marchioninistr 27, 81377 Munich, Germany
    J Reprod Immunol 90:74-81. 2011
  9. doi request reprint The molecular basis of leukocyte recruitment and its deficiencies
    Sarah Schmidt
    Walter Brendel Center for Experimental Medicine, Ludwig Maximilians Universitat, Munich, Germany
    Mol Immunol 55:49-58. 2013
  10. doi request reprint Myeloperoxidase: a leukocyte-derived protagonist of inflammation and cardiovascular disease
    Claudia Nussbaum
    Walter Brendel Centre for Experimental Medicine, Ludwig Maximilians University Munich, Munich, Germany
    Antioxid Redox Signal 18:692-713. 2013

Collaborators

  • David Frommhold
  • Matthias Klein
  • Uwe Koedel
  • Sven Hammerschmidt
  • Christian Kupatt
  • Udo Jeschke
  • Robert Pick
  • Klaus Ley
  • Claudia Nussbaum
  • Georg Stachel
  • Christopher Höhne
  • Sascha M Jakob
  • Sarah Schmidt
  • Barbara Walzog
  • Jurgen Schymeinsky
  • Rabea Hinkel
  • Stephan Baldus
  • Achim Pfosser
  • Angelika Bierhaus
  • Elizabeth Quackenbush
  • Matti Adam
  • Franziska Götz
  • Niklas Muenchmeier
  • Orsolya Genzel-Boroviczeny
  • Monika Pruenster
  • Michael Wenzel
  • Barbara Angele
  • Peter Jon Nelson
  • Antonis K Hatzopoulos
  • Anna Klinke
  • Markus Moser
  • Teresa Trenkwalder
  • Hans Walter Pfister
  • Doris Brechtefeld
  • Hans Hacker
  • Anna Gloning
  • Ulrich H von Andrian
  • Friedemann Kiefer
  • Chiraz El Aouni
  • Susanne Bierschenk

Detail Information

Publications13

  1. pmc Ontogenetic regulation of leukocyte recruitment in mouse yolk sac vessels
    Markus Sperandio
    Walter Brendel Center of Experimental Medicine, Ludwig Maximilians Universitat, Munich, Germany
    Blood 121:e118-28. 2013
    ..Taken together, our findings demonstrate that inflammation-induced leukocyte recruitment is ontogenetically regulated and enables efficient neutrophil trafficking only during late fetal life...
  2. doi request reprint Neutrophil and endothelial adhesive function during human fetal ontogeny
    Claudia Nussbaum
    1 Ludwig Maximilians Universität, Marchioninistr 27, 81377 Munich, Germany Twitter http www twitter com www sfb914 de
    J Leukoc Biol 93:175-84. 2013
    ..Thus, PMN recruitment and EC adhesion-related functions are ontogenetically regulated in the fetus, which might contribute significantly to the high risk of life-threatening infections in premature infants...
  3. doi request reprint The expanding role of α2-3 sialylation for leukocyte trafficking in vivo
    Markus Sperandio
    Walter Brendel Center of Experimental Medicine, Ludwig Maximilians Universitat, Munich, Germany
    Ann N Y Acad Sci 1253:201-5. 2012
    ..These findings make ST3Gal-IV an interesting drug target for modulating leukocyte trafficking in human disorders, including autoimmune diseases and cancer...
  4. pmc RAGE and ICAM-1 differentially control leukocyte recruitment during acute inflammation in a stimulus-dependent manner
    David Frommhold
    Department of Neonatology, University of Heidelberg, 20 Heidelberg, Germany
    BMC Immunol 12:56. 2011
    ....
  5. pmc Spleen tyrosine kinase Syk is critical for sustained leukocyte adhesion during inflammation in vivo
    David Frommhold
    Children s Hospital, Neonatal Unit, University of Heidelberg, Germany
    BMC Immunol 8:31. 2007
    ..During inflammation, beta2-integrins mediate leukocyte adhesion to the endothelium accompanied by the activation of the spleen tyrosine kinase Syk...
  6. pmc Glycosylation in immune cell trafficking
    Markus Sperandio
    Walter Brendel Center of Experimental Medicine, Ludwig Maximilians Universitat, Munich, Germany
    Immunol Rev 230:97-113. 2009
    ..Advancing the knowledge on glycan function into appropriate pathology models is likely to suggest interesting new therapeutic strategies in the treatment of immune- and inflammation-mediated diseases...
  7. doi request reprint Hematopoietic progenitor kinase 1 (HPK1) is required for LFA-1-mediated neutrophil recruitment during the acute inflammatory response
    Sascha M Jakob
    Walter Brendel Centre of Experimental Medicine, Ludwig Maximilians Universitat, Munich, Germany
    Blood 121:4184-94. 2013
    ..In summary, our results indicate that HPK1 is critically involved in LFA-1-mediated PMN trafficking during acute inflammation...
  8. doi request reprint Innate immune cell recruitment in the fetus and neonate
    Claudia Nussbaum
    Walter Brendel Center of Experimental Medicine, Ludwig Maximilians Universitat, Marchioninistr 27, 81377 Munich, Germany
    J Reprod Immunol 90:74-81. 2011
    ..In this review, an overview will be given of the developmental aspects of innate immune cell recruitment including a discussion of controversial findings and open questions...
  9. doi request reprint The molecular basis of leukocyte recruitment and its deficiencies
    Sarah Schmidt
    Walter Brendel Center for Experimental Medicine, Ludwig Maximilians Universitat, Munich, Germany
    Mol Immunol 55:49-58. 2013
    ..Finally, LAD-III, also known as LAD-I variant, is caused by impaired integrin activation due to mutations within the kindlin-3 gene. This review provides an overview on the molecular basis of leukocyte adhesion and its deficiencies...
  10. doi request reprint Myeloperoxidase: a leukocyte-derived protagonist of inflammation and cardiovascular disease
    Claudia Nussbaum
    Walter Brendel Centre for Experimental Medicine, Ludwig Maximilians University Munich, Munich, Germany
    Antioxid Redox Signal 18:692-713. 2013
    ..Despite advances in unraveling the complex action of MPO and MPO-derived oxidants, further research is warranted to determine the precise nature and biological role of MPO in inflammation...
  11. doi request reprint The mammalian actin-binding protein 1 (mAbp1): a novel molecular player in leukocyte biology
    Jurgen Schymeinsky
    Walter Brendel Centre for Experimental Medicine, Ludwig Maximilians University Munich, Munich, Germany
    Trends Cell Biol 21:247-55. 2011
    ..Here, we review the current understanding of the molecular and cellular functions of mAbp1 with a focus on its impact in leukocyte biology...
  12. doi request reprint High mobility group box 1 prolongs inflammation and worsens disease in pneumococcal meningitis
    Christopher Höhne
    Department of Neurology, Klinikum Grosshadern, Ludwig Maximilians University, Munich, Germany
    Brain 136:1746-59. 2013
    ..Because persistent inflammation contributes to meningitis-associated brain damage, high mobility group box 1 may represent a promising target for adjunctive therapy of this disease...
  13. ncbi request reprint SDF-1 Fused to a Fractalkine Stalk and a Gpi Anchor Enables Functional Neovascularization
    Georg Stachel
    Medizinische Klinik und Poliklinik I, Klinikum Gro hadern, Ludwig Maximilians University and DZHK German Centre for Cardiovascular Research, partner site Munich Heart Alliance, Munich, Germany
    Stem Cells . 2013
    ..Recombinant versions of S1FG applied via catheters, in combination with progenitor cell mobilization may be useful in the treatment of chronic ischemic syndromes requiring improved perfusion...