Karl Sotlar

Summary

Affiliation: University of Munich
Country: Germany

Publications

  1. ncbi request reprint Delineation of patterns of bone marrow mast cell infiltration in systemic mastocytosis: value of CD25, correlation with subvariants of the disease, and separation from mast cell hyperplasia
    Manuela Krokowski
    Institute of Pathology, University of Lubeck, Lubeck, Germany
    Am J Clin Pathol 124:560-8. 2005
  2. pmc Osteonecrosis of the jaw as a possible rare side effect of annual bisphosphonate administration for osteoporosis: A case report
    Sven Otto
    Department of Oral and Maxillofacial Surgery, Ludwig Maximilians University, Lindwurmstraße 2a, 80337 Munich, Germany
    J Med Case Reports 5:477. 2011
  3. doi request reprint Aberrant expression of CD30 in neoplastic mast cells in high-grade mastocytosis
    Karl Sotlar
    Institute of Pathology, University of Munich, Munich, Germany
    Mod Pathol 24:585-95. 2011
  4. doi request reprint Variable presence of KITD816V in clonal haematological non-mast cell lineage diseases associated with systemic mastocytosis (SM-AHNMD)
    Karl Sotlar
    Institute of Pathology, University of Munich, Germany
    J Pathol 220:586-95. 2010
  5. pmc Systemic mastocytosis associated with chronic idiopathic myelofibrosis: a distinct subtype of systemic mastocytosis associated with a [corrected] clonal hematological non-mast [corrected] cell lineage disorder carrying the activating point mutations KITD8
    Karl Sotlar
    Institute of Pathology, University of Tubingen, Liebermeisterstrasse 8, D 72076 Tubingen, Germany
    J Mol Diagn 10:58-66. 2008
  6. ncbi request reprint Fatal parvovirus B19-associated myocarditis clinically mimicking ischemic heart disease: an endothelial cell-mediated disease
    Burkhard D Bültmann
    Institute of Pathology, University of Tubingen, Tubingen, Germany
    Hum Pathol 34:92-5. 2003
  7. ncbi request reprint Mastocytosis: state of the art
    Hans Peter Horny
    Institute of Pathology, Ansbach, Germany
    Pathobiology 74:121-32. 2007
  8. ncbi request reprint CD25 indicates the neoplastic phenotype of mast cells: a novel immunohistochemical marker for the diagnosis of systemic mastocytosis (SM) in routinely processed bone marrow biopsy specimens
    Karl Sotlar
    Institute of Pathology, University of Tubingen, Tubingen, Germany
    Am J Surg Pathol 28:1319-25. 2004
  9. pmc One-step detection of c-kit point mutations using peptide nucleic acid-mediated polymerase chain reaction clamping and hybridization probes
    Karl Sotlar
    Institute of Pathology, University of Tubingen, Tubingen, Germany
    Am J Pathol 162:737-46. 2003
  10. ncbi request reprint Detection of c-kit point mutation Asp-816 --> Val in microdissected pooled single mast cells and leukemic cells in a patient with systemic mastocytosis and concomitant chronic myelomonocytic leukemia
    Karl Sotlar
    Institute of Pathology, University of Tubingen, Liebermeisterstrasse 8, D 72076, Tubingen, Germany
    Leuk Res 26:979-84. 2002

Detail Information

Publications17

  1. ncbi request reprint Delineation of patterns of bone marrow mast cell infiltration in systemic mastocytosis: value of CD25, correlation with subvariants of the disease, and separation from mast cell hyperplasia
    Manuela Krokowski
    Institute of Pathology, University of Lubeck, Lubeck, Germany
    Am J Clin Pathol 124:560-8. 2005
    ..Our data show that the infiltration pattern in SM correlates with the disease subtype and should be recognized as an important aspect in the histomorphologic evaluation of the bone marrow...
  2. pmc Osteonecrosis of the jaw as a possible rare side effect of annual bisphosphonate administration for osteoporosis: A case report
    Sven Otto
    Department of Oral and Maxillofacial Surgery, Ludwig Maximilians University, Lindwurmstraße 2a, 80337 Munich, Germany
    J Med Case Reports 5:477. 2011
    ..abstract:..
  3. doi request reprint Aberrant expression of CD30 in neoplastic mast cells in high-grade mastocytosis
    Karl Sotlar
    Institute of Pathology, University of Munich, Munich, Germany
    Mod Pathol 24:585-95. 2011
    ..Upregulated expression of CD30 in advanced systemic mastocytosis may thus be employed as a potential marker for grading systemic mastocytosis in hematopathology...
  4. doi request reprint Variable presence of KITD816V in clonal haematological non-mast cell lineage diseases associated with systemic mastocytosis (SM-AHNMD)
    Karl Sotlar
    Institute of Pathology, University of Munich, Germany
    J Pathol 220:586-95. 2010
    ....
  5. pmc Systemic mastocytosis associated with chronic idiopathic myelofibrosis: a distinct subtype of systemic mastocytosis associated with a [corrected] clonal hematological non-mast [corrected] cell lineage disorder carrying the activating point mutations KITD8
    Karl Sotlar
    Institute of Pathology, University of Tubingen, Liebermeisterstrasse 8, D 72076 Tubingen, Germany
    J Mol Diagn 10:58-66. 2008
    ..Altogether, these data suggest that KIT(D816V+) SM can co-exist with JAK2(V617F+) CIMF and that, in some of these SM-CIMF cases, the two mutations are present in the neoplastic cells of both disease components...
  6. ncbi request reprint Fatal parvovirus B19-associated myocarditis clinically mimicking ischemic heart disease: an endothelial cell-mediated disease
    Burkhard D Bültmann
    Institute of Pathology, University of Tubingen, Tubingen, Germany
    Hum Pathol 34:92-5. 2003
    ..We speculate that, due to the high viral load in cardiac ECs, PVB19 infection of endothelial cells was sufficient to induce impaired coronary microcirculation with secondary cardiac myocyte necrosis...
  7. ncbi request reprint Mastocytosis: state of the art
    Hans Peter Horny
    Institute of Pathology, Ansbach, Germany
    Pathobiology 74:121-32. 2007
    ....
  8. ncbi request reprint CD25 indicates the neoplastic phenotype of mast cells: a novel immunohistochemical marker for the diagnosis of systemic mastocytosis (SM) in routinely processed bone marrow biopsy specimens
    Karl Sotlar
    Institute of Pathology, University of Tubingen, Tubingen, Germany
    Am J Surg Pathol 28:1319-25. 2004
    ..CD25 therefore appears to be a reliable immunohistochemical marker for the discrimination of neoplastic from normal/reactive MCs, with potential as a diagnostic tool in SM...
  9. pmc One-step detection of c-kit point mutations using peptide nucleic acid-mediated polymerase chain reaction clamping and hybridization probes
    Karl Sotlar
    Institute of Pathology, University of Tubingen, Tubingen, Germany
    Am J Pathol 162:737-46. 2003
    ....
  10. ncbi request reprint Detection of c-kit point mutation Asp-816 --> Val in microdissected pooled single mast cells and leukemic cells in a patient with systemic mastocytosis and concomitant chronic myelomonocytic leukemia
    Karl Sotlar
    Institute of Pathology, University of Tubingen, Liebermeisterstrasse 8, D 72076, Tubingen, Germany
    Leuk Res 26:979-84. 2002
    ....
  11. ncbi request reprint Detection of high-risk human papillomavirus E6 and E7 oncogene transcripts in cervical scrapes by nested RT-polymerase chain reaction
    Karl Sotlar
    Institute of Pathology, University of Tuebingen, Germany
    J Med Virol 74:107-16. 2004
    ..Future applications of the assay described may include the monitoring of women in studies investigating antiviral treatment or vaccination...
  12. ncbi request reprint Diagnostic value of histology and immunohistochemistry in myelodysplastic syndromes
    Hans Peter Horny
    Institute of Pathology, D 91522 Ansbach, Germany
    Leuk Res 31:1609-16. 2007
    ..Histologic/immunohistochemical investigation of the bone marrow therefore is strongly recommended for patients with (suspected) MDS, the minimum marker-panel suggested being CD31, CD34, and tryptase...
  13. doi request reprint c-kit mutational analysis in paraffin material
    Karl Sotlar
    Institute of Pathology, University of Munich, Munich, Germany
    Methods Mol Biol 999:59-78. 2013
    ....
  14. doi request reprint Adult-onset mastocytosis in the skin is highly suggestive of systemic mastocytosis
    Sabina Berezowska
    Institute of Pathology, University of Munich, Munich, Germany
    Mod Pathol 27:19-29. 2014
    ..This study demonstrates, for the first time, that almost all patients with adult-onset mastocytosis in the skin, in fact, have systemic mastocytosis with cutaneous involvement. ..
  15. ncbi request reprint Expression of KIT (CD117) in renal cell carcinoma and renal oncocytoma
    Stefan Kruger
    Institute of Pathology, University of Schleswig Holstein, Campus Lubeck, Lubeck, Germany
    Oncology 68:269-75. 2005
    ..Our aim was to analyze KIT expression immunohistochemically in renal cell carcinomas (RCCs) and in oncocytomas...
  16. ncbi request reprint Bone marrow mastocytosis associated with IgM kappa plasma cell myeloma
    Florian Stellmacher
    Institute of Pathology, University of Lubeck, Ratzeburger Allee 160, D 23538, Lubeck, Germany
    Leuk Lymphoma 45:801-5. 2004
    ....
  17. ncbi request reprint Parvovirus B19: a pathogen responsible for more than hematologic disorders
    Burkhard D Bültmann
    Institute of Pathology, University of Tubingen, Liebermeisterstrasse 8, D 72076 Tubingen, Germany
    Virchows Arch 442:8-17. 2003
    ..Because treatment of lytic PVB19 infection has been successfully applied, the pathologist should be alerted to include PVB19 into the diagnostic spectrum of viral disease, especially in immunocompromised patients...