G C Sotiropoulos

Summary

Affiliation: University of Essen
Country: Germany

Publications

  1. ncbi request reprint Arterioportal fistula complicating endoscopic retrograde cholangiography
    G C Sotiropoulos
    Department of General Surgery and Transplantation, University Hospital Essen, Essen, Germany
    Endoscopy 37:93-4. 2005
  2. ncbi request reprint Recurrent giant biloma following deceased donor split liver transplantation
    Georgios C Sotiropoulos
    Department of General, Visceral and Transplantation Surgery, University Hospital Essen, Hufelandstr 55, 45122 Essen, Germany
    Eur J Med Res 12:609. 2007
  3. ncbi request reprint Biliary tract obstruction due to sarcoidosis
    G C Sotiropoulos
    Department of General Surgery and Transplantation, University Hospital Essen, Essen, Germany
    Endoscopy 37:1262. 2005
  4. ncbi request reprint Disease course after liver transplantation for hepatocellular carcinoma in patients with complete tumor necrosis in liver explants after performance of bridging treatments
    Georgios C Sotiropoulos
    Department of General Surgery and Transplantation, University Hospital Essen, Germany
    Eur J Med Res 10:539-42. 2005
  5. ncbi request reprint Liver transplantation and incidentally found hepatocellular carcinoma in liver explants: need for a new definition?
    Georgios C Sotiropoulos
    Department of General Surgery and Transplantation, University Hospital Essen, Essen, Germany
    Transplantation 81:531-5. 2006
  6. doi request reprint Liberal policy in living donor liver transplantation for hepatocellular carcinoma: lessons learned
    Georgios C Sotiropoulos
    Department of General, Visceral, and Transplantation Surgery, University Hospital Essen, Hufelandstr 55, 45122, Essen, Germany
    Dig Dis Sci 54:377-84. 2009
  7. ncbi request reprint Meta-analysis of tumor recurrence after liver transplantation for hepatocellular carcinoma based on 1,198 cases
    Georgios C Sotiropoulos
    Department of General, Visceral and Transplantation Surgery, University Hospital Essen, Hufelandstr 55, 45122 Essen, Germany
    Eur J Med Res 12:527-34. 2007
  8. ncbi request reprint Liver transplantation for hepatocellular carcinoma: University Hospital Essen experience and metaanalysis of prognostic factors
    Georgios C Sotiropoulos
    Department of General, Visceral and Transplantation Surgery, University Hospital Essen, Essen, Germany
    J Am Coll Surg 205:661-75. 2007
  9. ncbi request reprint Single-center experience on liver transplantation for hepatocellular carcinoma arising in alcoholic cirrhosis: results and ethical issues
    G C Sotiropoulos
    Department of General, Visceral, and Transplantation Surgery, University Hospital Essen, Essen, Germany
    Eur Surg Res 40:7-13. 2008
  10. ncbi request reprint Hilar lymph nodes sampling at the time of liver transplantation for hepatocellular carcinoma: to do or not to do? Meta-analysis to determine the impact of hilar lymph nodes metastases on tumor recurrence and survival in patients with hepatocellular carcin
    Georgios C Sotiropoulos
    Department of General, Visceral and Transplantation Surgery, University Hospital Essen, Essen, Germany
    Transpl Int 20:141-6. 2007

Collaborators

Detail Information

Publications131 found, 100 shown here

  1. ncbi request reprint Arterioportal fistula complicating endoscopic retrograde cholangiography
    G C Sotiropoulos
    Department of General Surgery and Transplantation, University Hospital Essen, Essen, Germany
    Endoscopy 37:93-4. 2005
  2. ncbi request reprint Recurrent giant biloma following deceased donor split liver transplantation
    Georgios C Sotiropoulos
    Department of General, Visceral and Transplantation Surgery, University Hospital Essen, Hufelandstr 55, 45122 Essen, Germany
    Eur J Med Res 12:609. 2007
    ..We report herein the case of a patient with a recurrent giant biloma following deceased donor split LT, which despite its volume was treated conservatively...
  3. ncbi request reprint Biliary tract obstruction due to sarcoidosis
    G C Sotiropoulos
    Department of General Surgery and Transplantation, University Hospital Essen, Essen, Germany
    Endoscopy 37:1262. 2005
  4. ncbi request reprint Disease course after liver transplantation for hepatocellular carcinoma in patients with complete tumor necrosis in liver explants after performance of bridging treatments
    Georgios C Sotiropoulos
    Department of General Surgery and Transplantation, University Hospital Essen, Germany
    Eur J Med Res 10:539-42. 2005
    ..To study the disease course of patients with hepatocellular carcinoma (HCC) showing complete tumor necrosis in their liver explants after undergoing bridging treatments followed by liver transplantation (LTx)...
  5. ncbi request reprint Liver transplantation and incidentally found hepatocellular carcinoma in liver explants: need for a new definition?
    Georgios C Sotiropoulos
    Department of General Surgery and Transplantation, University Hospital Essen, Essen, Germany
    Transplantation 81:531-5. 2006
    ..The purpose of this study was to evaluate the outcome of patients with these tumors in our series and in literature reports, and to compare their prognosis to that of HCC diagnosed preoperatively...
  6. doi request reprint Liberal policy in living donor liver transplantation for hepatocellular carcinoma: lessons learned
    Georgios C Sotiropoulos
    Department of General, Visceral, and Transplantation Surgery, University Hospital Essen, Hufelandstr 55, 45122, Essen, Germany
    Dig Dis Sci 54:377-84. 2009
    ..The aim of this study was to evaluate survival and prognostic factors associated with a liberal exclusionary policy...
  7. ncbi request reprint Meta-analysis of tumor recurrence after liver transplantation for hepatocellular carcinoma based on 1,198 cases
    Georgios C Sotiropoulos
    Department of General, Visceral and Transplantation Surgery, University Hospital Essen, Hufelandstr 55, 45122 Essen, Germany
    Eur J Med Res 12:527-34. 2007
    ..The purpose of this study was to systematically review tumor characteristics leading to recurrence of hepatocellular carcinoma (HCC) after liver transplantation (LT)...
  8. ncbi request reprint Liver transplantation for hepatocellular carcinoma: University Hospital Essen experience and metaanalysis of prognostic factors
    Georgios C Sotiropoulos
    Department of General, Visceral and Transplantation Surgery, University Hospital Essen, Essen, Germany
    J Am Coll Surg 205:661-75. 2007
    ..The purpose of this study was to correlate pathologic findings with outcomes after liver transplantation for hepatocellular carcinoma and to evaluate associations between various tumor characteristics and patient outcomes...
  9. ncbi request reprint Single-center experience on liver transplantation for hepatocellular carcinoma arising in alcoholic cirrhosis: results and ethical issues
    G C Sotiropoulos
    Department of General, Visceral, and Transplantation Surgery, University Hospital Essen, Essen, Germany
    Eur Surg Res 40:7-13. 2008
    ..The purpose of this study was to evaluate the outcome of patients with HCC and ALD in the absence of viral hepatitic infections...
  10. ncbi request reprint Hilar lymph nodes sampling at the time of liver transplantation for hepatocellular carcinoma: to do or not to do? Meta-analysis to determine the impact of hilar lymph nodes metastases on tumor recurrence and survival in patients with hepatocellular carcin
    Georgios C Sotiropoulos
    Department of General, Visceral and Transplantation Surgery, University Hospital Essen, Essen, Germany
    Transpl Int 20:141-6. 2007
    ..Given the ever-present diagnostic dilemma associated with enlarged hilar LN, especially in hepatitis C-positive patients, hilar LN sampling during LT for HCC could better define patients at risk...
  11. ncbi request reprint Surgery for hepatocellular carcinoma arising in hereditary hemochromatosis
    Georgios C Sotiropoulos
    Department of General, Visceral and Transplantation Surgery, University Hospital Essen, Essen, Germany
    Eur Surg Res 38:371-6. 2006
    ..The benefit of surgical therapy in this clinical entity is not well documented. The purpose of this study was to evaluate the outcome of such patients both in our own experience as well as in the published literature...
  12. ncbi request reprint Liver transplantation for hepatocellular carcinoma in patients beyond the Milan but within the UCSF criteria
    Georgios C Sotiropoulos
    Department of General, Visceral and Transplantation Surgery, University Hospital Essen, Hufelandstrasse 55, 45122 Essen, Germany
    Eur J Med Res 11:467-70. 2006
    ..Poor information is available about the real "gain" in patients' outcome when extending the listing criteria from Milan to UCSF...
  13. ncbi request reprint Surgical treatment of pancreatic metastases of renal cell carcinoma
    Georgios C Sotiropoulos
    Department of General Surgery and Transplantation, University Hospital Essen, Germany
    JOP 6:339-43. 2005
    ..We herein present two cases of pancreatic metastases of renal cell carcinoma which occurred 17 and 19 years after the primary diagnosis...
  14. ncbi request reprint Intraoperative cholangioscopy in the management of biliary adenomas
    Georgios C Sotiropoulos
    Department of General Surgery and Transplantation, University Hospital Essen, Hufelandstrasse 55, D 45122 Essen, Germany
    J Surg Oncol 85:91-2. 2004
  15. ncbi request reprint Living organ donation: is there still place for altruism?
    Georgios C Sotiropoulos
    Department of General Surgery and Transplantation, University Hospital Essen, Essen, Germany
    Hepatogastroenterology 51:6-8. 2004
    ..Monetary incentives can have only short-term results in increasing the number of donors; they can also increase the exploitation of poor people and, in the long run, destroy the concept of donation, dissuading the altruistic donors...
  16. ncbi request reprint Hemangioendothelioma of the liver associated with a solitary extrahepatic lesion
    Georgios C Sotiropoulos
    Department of General Surgery and Transplantation, University Hospital Essen, Germany
    Hepatogastroenterology 51:436-8. 2004
    ..The tumor was associated with a solitary extrahepatic lesion, which was first discovered six months after the liver resection and which was also resected...
  17. ncbi request reprint Staging laparoscopy in gastric cancer
    G C Sotiropoulos
    Department of General Surgery and Transplantation, University Hospital Essen, Germany
    Eur J Med Res 10:88-91. 2005
    ..Laparoscopy has been suggested as an appropriate staging modality in a variety of upper gastrointestinal malignancies...
  18. ncbi request reprint Donor/recipient algorithm for management of the middle hepatic vein in right graft live donor liver transplantation
    A Radtke
    Department of General, Visceral and Transplantation Surgery, University Hospital Essen, Essen, Germany
    Am J Surg 199:708-15. 2010
    ....
  19. doi request reprint A new systematic classification of peripheral anatomy of the right hepatic duct: experience from adult live liver donor transplantation
    A Radtke
    Department of General and Abdominal Surgery, Johannes Gutenberg University Hospital, Mainz, Germany Department of General, Visceral, and Transplantation Surgery, University Hospital Essen, Essen, Germany
    Transplant Proc 40:3158-60. 2008
    ..The purpose of our study was to systematically describe this complex anatomy in clinically applicable fashion...
  20. doi request reprint Living donor liver transplantation for hepatocellular carcinoma in patients exceeding the UCSF criteria
    I Fouzas
    Department of General, Visceral, and Transplantation Surgery, University Hospital, Essen, Germany Organ Transplant Unit, Hippocration University Hospital, Thessaloniki, Greece
    Transplant Proc 40:3185-8. 2008
    ..The purpose of this study was to demonstrate our institutional experience using criteria exceeding those of the University of California San Francisco (UCSF)...
  21. doi request reprint Liver "compliance": a previously unrecognized preoperative predictor of small-for-size syndrome in adult living donor liver transplantation
    A Radtke
    Department of General and Abdominal Surgery, Johannes Gutenberg University Hospital, Mainz, Germany Department of General, Visceral, and Transplantation Surgery, University Hospital Essen, Essen, Germany
    Transplant Proc 40:3142-6. 2008
    ..The purpose of this study was to investigate the effect of liver compliance on computed tomography (CT) volumetry and to determine its association with postoperative small-for-size syndrome (SFSS)...
  22. ncbi request reprint Preoperative volume prediction in adult living donor liver transplantation: how much can we rely on it?
    A Radtke
    Departments of General, Visceral and Transplantation Surgery, University Hospital Essen, Essen, Germany
    Am J Transplant 7:672-9. 2007
    ..While 3-D CT volumetry based on the 'largest' (venous) CT phase is associated with considerable overestimation, 3-D volumetry based on the 'smallest' (native) CT phase accurately matches the intraoperative findings...
  23. ncbi request reprint Computer-assisted operative planning in adult living donor liver transplantation: a new way to resolve the dilemma of the middle hepatic vein
    A Radtke
    Department of General, Visceral and Transplantation Surgery, University Hospital Essen, Hufelandstrasse 55, D 45122, Essen, Germany
    World J Surg 31:175-85. 2007
    ..This comprehensive data acquisition supports preoperative evaluation and provides a high degree of safety for donors and improved outcomes for recipients...
  24. ncbi request reprint Preoperative volume prediction in adult live donor liver transplantation: 3-D CT volumetry approach to prevent miscalculations
    A Radtke
    Department of General, Visceral and Transplantation Surgery, University Hospital Essen, Essen, Germany
    Eur J Med Res 13:319-26. 2008
    ..The purpose of this study was to describe and validate our modus 3-D CT volumetry...
  25. doi request reprint Hepatic hilar and sectorial vascular and biliary anatomy in right graft adult live liver donor transplantation
    A Radtke
    Department of General and Abdominal Surgery, Johannes Gutenberg University Hospital, Mainz, Germany Department of General, Visceral, and Transplantation Surgery, University Hospital Essen, Essen, Germany
    Transplant Proc 40:3147-50. 2008
    ..The aim of this study was to analyze vascular and biliary variants at the hilar and sectorial level in right graft adult living donor liver transplantation...
  26. doi request reprint Intrahepatic biliary anatomy derived from right graft adult live donor liver transplantation
    A Radtke
    Department of General and Abdominal Surgery, Johannes Gutenberg University Hospital, Mainz, Germany Department of General, Visceral, and Transplantation Surgery, University Hospital Essen, Essen, Germany
    Transplant Proc 40:3151-4. 2008
    ..The purpose of this study was to provide a systematic classification of its branching patterns to enhance clinical decision-making...
  27. doi request reprint Anatomical classification of the peripheral right hepatic duct: early identification of a preventable source of morbidity and mortality in adult live donor liver transplantation
    A Radtke
    Department of General and Abdominal Surgery, Johannes Gutenberg University Hospital, Mainz, Germany Department of General, Visceral, and Transplantation Surgery, University Hospital Essen, Essen, Germany
    Transplant Proc 40:3155-7. 2008
    ..The purpose of this study was to determine the impact of our classification on right graft adult live donor liver transplantation (ALDLT) outcomes...
  28. doi request reprint Liver transplantation as a primary indication for intrahepatic cholangiocarcinoma: a single-center experience
    G C Sotiropoulos
    Department of General, Visceral, and Transplantation Surgery, University Hospital Essen, Essen, Germany Department of General and Abdominal Surgery, Johannes Gutenberg University Hospital, Mainz, Germany
    Transplant Proc 40:3194-5. 2008
    ..The present study describes our institutional experience with patients who underwent transplantation for ICC as well as those with ICC who underwent transplantation with the incorrect diagnosis of hepatocellular carcinoma (HCC)...
  29. doi request reprint Territorial belonging of the middle hepatic vein in living liver donor candidates evaluated by three-dimensional computed tomographic reconstruction and virtual liver resection
    A Radtke
    Department of General, Visceral and Transplantation Surgery, University Hospital Essen, Essen, Germany
    Br J Surg 96:206-13. 2009
    ..This study was designed to delineate 'territorial belonging' of the middle hepatic vein (MHV) and to identify hepatic venous anatomy at high risk of outflow congestion...
  30. ncbi request reprint Major liver resections for primary liver malignancies in the elderly
    G Sgourakis
    Department of General, Visceral and Transplantation Surgery, University Hospital Essen, Essen, Germany
    Acta Chir Belg 109:340-4. 2009
    ..The aim of our prospective study was to assess the results of major hepatic resections for primary liver tumours in patients 75 years of age or older...
  31. ncbi request reprint The "territorial belonging" of the middle hepatic vein: a troublesome dilemma in adult live donor liver transplantation--anatomical evidence based on virtual 3-dimensional-computed tomography-imaging reconstructions
    A Radtke
    Department of General Surgery and Transplantation, University Hospital Essen, Hufelandstr 55, D 45122 Essen, Germany
    Eur J Med Res 11:66-72. 2006
    ..The purpose of this study was to analyze hepatic venous drainage patterns based on information obtained by 3-dimensional CT-imaging reconstructions...
  32. doi request reprint Liver transplantation with grafts from septuagenarians
    I Fouzas
    Department of General, Visceral, and Transplantation Surgery, University Hospital Essen, Essen, Germany Organ Transplant Unit, Hippocration University Hospital, Thessaloniki, Greece
    Transplant Proc 40:3198-200. 2008
    ..The purpose of this study was to evaluate our experience with orthotopic liver transplantation (OLT) using grafts from septuagenarians...
  33. doi request reprint Incidence of liver retransplantation and its effect on patient survival
    H Lang
    Department of General and Abdominal Surgery, Johannes Gutenberg University Hospital, Mainz, Germany Department of General, Visceral, and Transplantation Surgery, University Hospital Essen, Essen, Germany
    Transplant Proc 40:3201-3. 2008
    ..The purpose of this study was to review our institutional experience with re-liver transplantation (OLT) after split and full-size OLT...
  34. doi request reprint Long-term results after liver transplantation with "livers that nobody wants" within Eurotransplant: a center's experience
    G C Sotiropoulos
    Department of General, Visceral, and Transplantation Surgery, University Hospital Essen, Essen, Germany Department of General and Abdominal Surgery, Johannes Gutenberg University Hospital, Mainz, Germany
    Transplant Proc 40:3196-7. 2008
    ..The purpose of this study was to review the long-term outcomes after OLT during a 2-year period of 45 rescue offers organs within Eurotransplant...
  35. doi request reprint Five-year survival after monotherapy for hepatocellular carcinoma in the setting of cirrhosis
    I Fouzas
    Department of General, Visceral, and Transplantation Surgery, University Hospital, Essen, Germany Organ Transplant Unit, Hippocration University Hospital, Thessaloniki, Greece
    Transplant Proc 40:3204-5. 2008
    ..The alpha-fetoprotein level was demonstrated to be prognostic of recurrence by discriminant function analysis. In conclusion, OLT provided the best long-term results as monotherapy for HCC in the setting of cirrhosis...
  36. doi request reprint Eurotransplant special request for high-urgency status after liver transplantation for hepatocellular carcinoma: a case report
    G C Sotiropoulos
    Department of General, Visceral, and Transplantation Surgery, University Hospital Essen, Essen, Germany Department of General and Abdominal Surgery, Johannes Gutenberg University Hospital, Mainz, Germany
    Transplant Proc 40:3211-2. 2008
    ..The existence of exceptions within the system, such as the "special high-urgency status" of Eurotransplant, as well as the aggressive treatment of complications to obtain a "window of clinical opportunity" saved this patient's life...
  37. ncbi request reprint Combined mycophenolate mofetil and minimal dose calcineurin inhibitor therapy in liver transplant patients: clinical results of a prospective randomized study
    S Beckebaum
    Department of General, Visceral and Transplantation Surgery, University Hospital Essen, Essen, Germany
    Transplant Proc 41:2567-9. 2009
    ..Long-term complications of calcineurin inhibitor (CNI)-based immunosuppression after liver transplantation (LT) have a marked impact on patient morbidity and mortality...
  38. doi request reprint Transhilar passage in right graft live donor liver transplantation: intrahilar anatomy and its impact on operative strategy
    A Radtke
    Department of General, Thoracic and Transplantation Surgery, University Hospital Schleswig Holstein, Campus Kiel, Germany
    Am J Transplant 12:718-27. 2012
    ..2) A stepwise transhilar passage was favored in types III and IV inside the right-sided hilar corridor. (3) Reconstruction techniques showed no ameliorating effect on early/late biliary morbidity rates...
  39. doi request reprint Liver transplantation for hepatocellular carcinoma after yttrium therapy: a case report
    G C Sotiropoulos
    Department of General, Visceral, and Transplantation Surgery, University Hospital Essen, Essen, Germany
    Transplant Proc 40:3804-5. 2008
    ..This report provided encouraging information on the potential of yttrium-90 microspheres as a bridging option before OLT for multifocal HCC...
  40. ncbi request reprint [Surgical therapy of hilar cholangiocarcinoma]
    H Lang
    Klinik fUr Allgemein, Viszeral und Transplantationschirurgie, Universitatsklinikum Essen, Hufelandstrasse 55, 45122 Essen
    Chirurg 77:325-34. 2006
    ..The increasing experience with living donor transplantation and recent advances in neoadjuvant tumor therapy may lead to renewed discussion of liver transplantation in hilar cholangiocarcinoma...
  41. doi request reprint Renal function and cardiovascular risk profile after conversion from ciclosporin to tacrolimus: prospective study in 80 liver transplant recipients
    S Beckebaum
    Department of General, Visceral and Transplantation Surgery, University Hospital Essen, Essen, Germany
    Aliment Pharmacol Ther 30:834-42. 2009
    ..Several studies have demonstrated a more favourable outcome for patients receiving tacrolimus (TAC) as compared with ciclosporin (CS)...
  42. doi request reprint "Preemptive" live donor liver transplantation for fibrolamellar hepatocellular carcinoma: a case report
    I Fouzas
    Department of General, Visceral and Transplantation Surgery, University Hospital Essen, Essen, Germany
    Transplant Proc 40:3806-7. 2008
    ..Herein we have reported successful "preemptive" living donor liver transplantation for presumed recurrence of FL-HCC after an extended right hepatectomy with resection and synthetic graft replacement of the inferior vena cava...
  43. ncbi request reprint Liver resection for hepatocellular carcinoma in non-cirrhotic liver without underlying viral hepatitis
    H Lang
    Klinik für Allgemein und Transplantationschirurgie, University Hospital Essen, Germany
    Br J Surg 92:198-202. 2005
    ..Hepatocellular carcinoma (HCC) arising in normal liver parenchyma is rare and the outcome after hepatectomy is not well documented...
  44. doi request reprint Incarcerated diaphragmatic hernia after right hepatectomy for living donor liver transplantation: case report of an extremely rare late donor complication
    S Vernadakis
    Department of General, Visceral and Transplantation Surgery, University Hospital Essen, Essen, Germany
    Transplant Proc 44:2770-2. 2012
    ..The diaphragmatic hernia was repaired. Diaphragmatic hernia is a rarely reported complication of right donor hepatectomy for transplantation and should be considered to be a potential late complication...
  45. doi request reprint Liver transplantation for hepatocellular carcinoma using extended criteria donor grafts
    G C Sotiropoulos
    Department of General, Visceral and Transplantation Surgery, University Hosiptal Essen, Essen, Germany
    Transplant Proc 44:2730-3. 2012
    ..However, because of organ scarcity, alternative options must be explored, such as the use of extended criteria donor (ECD) grafts...
  46. doi request reprint Orthotopic liver transplantation in patients with portal vein thrombosis in the absence of hepatocellular carcinoma
    I Fouzas
    Department of General, Visceral and Transplantation Surgery, University Hospital Essen, Essen, Germany
    Transplant Proc 44:2734-6. 2012
    ..Liver transplantation (OLT) in the setting of portal vein thrombosis (PVT) has been a matter of controversy in the past. We herein report our experience with OLT for PVT in the absence of hepatocellular carcinoma...
  47. doi request reprint Liver transplantation for hepatocellular carcinoma with intrahepatic lymphatic invasion: case reports
    G C Sotiropoulos
    Department of General, Visceral, and Transplantation Surgery, University Hospital Essen, Essen, Germany Department of General and Abdominal Surgery, Johannes Gutenberg University Hospital, Mainz, Germany
    Transplant Proc 40:3213-4. 2008
    ..Intrahepatic lymphatic invasion may not be an absolute adverse prognostic factor in cases of HCC with no hilar lymph node involvement at the time of OLT...
  48. ncbi request reprint Clinical trial: switch to combined mycophenolate mofetil and minimal dose calcineurin inhibitor in stable liver transplant patients--assessment of renal and allograft function, cardiovascular risk factors and immune monitoring
    V R Cicinnati
    Department of Gastroenterology and Hepatology, University Hospital Essen, Essen, Germany
    Aliment Pharmacol Ther 26:1195-208. 2007
    ..Calcineurin inhibitor (CNI)-related nephrotoxicity significantly contributes to chronic renal failure after liver transplantation...
  49. doi request reprint Role of osteopontin and CD44s expression for patients with hepatocellular carcinoma undergoing liver transplantation or resection
    S Beckebaum
    Department of Gastroenterology and Hepatology, Department of General, Visceral, and Transplantation Surgery, University Hospital Essen, University of Duisburg, Essen, Germany
    Transplant Proc 40:3182-4. 2008
    ..Cluster differentiation 44 standard isoform (CD44s) is one of the primary receptors of OPN; it may contribute to metastatic tumor spread...
  50. doi request reprint Cholecystectomy due to symptomatic gallbladder disease after orthotopic liver transplantation: report of three cases
    S Vernadakis
    Department of General, Visceral and Transplantation Surgery, University Hospital Essen, Essen, Germany
    Transplant Proc 44:2757-8. 2012
    ..Herein we have reported three cases of successful either laparoscopic or open cholecystectomy for symptomatic cholecystolithiasis or acute cholecystitis between 14 and 19 years after OLT, as well as a systematic literature review...
  51. ncbi request reprint Effect of low-dose rapamycin on tumor growth in two human hepatocellular cancer cell lines
    M Heuer
    Department of General, Visceral and Transplantation Surgery, University Hospital of Essen, Essen, Germany
    Transplant Proc 41:359-65. 2009
    ..The newly developed immunosuppressive drug rapamycin may aid to lower recurrence rates. We investigated the efficiency of rapamycin as compared with previous immunosuppressants in a tumor cell model...
  52. ncbi request reprint Anatomical and physiological classification of hepatic vein dominance applied to liver transplantation
    A Radtke
    Department of General Surgery and Transplantation, University Hospital Essen, Hufelandstr 55, D 45122 Essen, Germany
    Eur J Med Res 10:187-94. 2005
    ..The purpose of our study was to provide a combined anatomical-physiological classification of hepatic vein dominance useful for surgical decision-making in both donors and recipients...
  53. doi request reprint Claudin-7 expression in hepatocellular carcinoma
    E I Brokalaki
    Department of General, Visceral and Transplantation Surgery, University Hospital Essen, Essen, Germany
    Transplant Proc 44:2737-40. 2012
    ..Claudins are integral parts of tight junctions. The aim of the present study was to examine the significance of the expression of claudin-7 messenger RNA (mRNA) as a prognostic factor for hepatocellular carcinoma (HCC)...
  54. ncbi request reprint Cyclo-oxygenase-2 overexpression is a feature of early and well-differentiated hepatocellular carcinoma with a favourable prognosis
    K J Schmitz
    Institute of Pathology and Neuropathology, University Hospital Essen, University of Duisburg Essen, Hufelandstrasse 55, Essen 45122, Germany
    J Clin Pathol 62:690-3. 2009
    ..To determine the prognostic relevance of cyclo-oxygenase-2 (COX-2) expression in hepatocellular carcinoma (HCC) and its relationship to important clinicopathological parameters...
  55. ncbi request reprint Ribavirin with either standard or pegylated interferon to treat recurrent hepatitis C after liver transplantation
    V R Cicinnati
    Department of Gastroenterology and Hepatology, University Hospital Essen, University of Duisburg Essen, Essen, Germany
    Aliment Pharmacol Ther 26:291-303. 2007
    ..To investigate the efficacy of two anti-viral protocols in hepatitis C virus-reinfected liver transplant recipients...
  56. doi request reprint Operations for intrahepatic cholangiocarcinoma: single-institution experience of 158 patients
    Hauke Lang
    Department of General, Visceral and Transplantation Surgery, University Hospital Essen, Essen, Germany
    J Am Coll Surg 208:218-28. 2009
    ..Intrahepatic cholangiocarcinoma (ICC) is a rare primary liver malignancy. Until now, outcomes and prognostic factors after liver resection for these tumors have not been well-documented...
  57. doi request reprint Successful salvage delivery and liver transplantation for fulminant hepatic failure in a 34-week pregnant woman: a case report
    S Vernadakis
    Department of General Visceral and Transplantation Surgery, University Hospital Essen, Essen, Germany
    Transplant Proc 44:2768-9. 2012
    ..This case illustrates the challenge of treating this rare condition and demonstrates that a salvage double surgical approach-emergency delivery and OLT-is a feasible therapeutic option for treatment of these patients...
  58. doi request reprint Sorafenib treatment for recurrent hepatocellular carcinoma after liver transplantation
    G C Sotiropoulos
    Department of General, Visceral and Transplantation Surgery, University Hospital Essen, Essen, Germany
    Transplant Proc 44:2754-6. 2012
    ..We herein report our experience with sorafenib treatment for HCC recurrence post-OLT...
  59. pmc When the heart kills the liver: acute liver failure in congestive heart failure
    F H Saner
    Department of General, Visceral and Transplant Surgery, University Hospital Essen, Germany
    Eur J Med Res 14:541-6. 2009
    ..In conclusion, patients with acute liver failure require an appropriate diagnostic approach. Congestive heart failure should always be considered as a possible cause of acute liver failure...
  60. doi request reprint Intensive care unit management of liver transplant patients: a formidable challenge for the intensivist
    F H Saner
    Department of General, Visceral, and Transplant Surgery, University Hospital Essen, Essen, Germany
    Transplant Proc 40:3206-8. 2008
    ..This review will focus on these topics to provide useful information concerning pathophysiology and treatment. Intensivists, who are involved in the postoperative care of liver transplant patients, have to be aware of these problems...
  61. ncbi request reprint Liver transplantation, liver resection, and transarterial chemoembolization for hepatocellular carcinoma in cirrhosis: which is the best oncological approach?
    Georgios C Sotiropoulos
    Department of General, Visceral and Transplantation Surgery, University Hospital Essen, Essen, Germany
    Dig Dis Sci 54:2264-73. 2009
    ..Considering the scarcity of available organs, liver resection remains the best alternative option. TACE remains a potential therapy in patients within the Milan criteria, where it may be more beneficial than resection...
  62. ncbi request reprint Established and emerging therapies for hepatocellular carcinoma
    V R Cicinnati
    Department of Gastroenterology and Hepatology, University of Duisburg Essen, Essen, Germany
    Minerva Med 101:405-18. 2010
    ..Further improved understanding of molecular mechanisms underlying HCC development will facilitate the development of new targeted therapeutic strategies...
  63. ncbi request reprint Multicentric evaluation of a clinical and prognostic scoring system predictive of survival after resection of intrahepatic cholangiocarcinomas
    Georgios C Sotiropoulos
    Department of General, Visceral and Transplantation Surgery, University Hospital Essen, Essen, Germany
    Liver Int 30:996-1002. 2010
    ..To develop a clinical and prognostic scoring system predictive of survival after resection of intrahepatic cholangiocarcinomas (ICC)...
  64. pmc GNAS1 T393C polymorphism is associated with clinical course in patients with intrahepatic cholangiocarcinoma
    Klaus J Schmitz
    Institute of Pathology and Neuropathology, University of Duisburg Essen, Essen, Germany
    Neoplasia 9:159-65. 2007
    ..We have recently shown that TT genotypes of the single-nucleotide polymorphism T393C in the gene GNAS1 predict the clinical outcome of patients with various carcinomas...
  65. ncbi request reprint Parenchyma transection in adult live donor liver transplantation: the virtual dilemma of "where to cut". Experience based on virtual 3-dimensional computed tomography imaging reconstructions
    Arnold Radtke
    Department of General, Visceral and Transplantation Surgery University Hospital Essen, Essen, Germany
    Hepatogastroenterology 53:811-5. 2006
    ..The purpose of our study was to evaluate two types of liver transection techniques (Cantlie, Malagó) frequently encountered in ALDLT and to determine their resulting anatomical and functional liver graft volumes...
  66. ncbi request reprint Liver transplantation for hepatocellular carcinoma in cirrhosis within the Eurotransplant area: an additional option with "livers that nobody wants"
    Georgios C Sotiropoulos
    Department of General Surgery and Transplantation, University Hospital Essen, Essen, Germany
    Transplantation 80:897-902. 2005
    ..However, because of limited organ availability, not all those who qualify can benefit from it...
  67. ncbi request reprint Current trends in live liver donation
    Silvio Nadalin
    Department of General, Visceral and Transplantation Surgery, University Hospital Essen, Essen, Germany
    Transpl Int 20:312-30. 2007
    ..Knowing in detail how to approach to the different aspects of living liver donation may be helpful in further improve donor's safety and even recipient's outcome...
  68. ncbi request reprint Efficacy of transarterial chemoembolization prior to liver transplantation for hepatocellular carcinoma as found in pathology
    Georgios C Sotiropoulos
    Department of General Surgery and Transplantation, University Hospital Essen, Germany
    Hepatogastroenterology 52:329-32. 2005
    ..To analyze the efficacy of chemoembolization prior to liver transplantation in liver explants...
  69. doi request reprint Major liver resections in the elderly-is an aggressive approach justified?
    Maximilian Bockhorn
    Department of General, Visceral and Transplantation Surgery, University Hospital Essen, Essen, Germany
    Int J Colorectal Dis 24:83-6. 2009
    ..The purpose of our study was to evaluate the outcome of major hepatic resections in the elderly population...
  70. ncbi request reprint Hepatic venous drainage: how much can we learn from imaging studies? Anatomic-functional classification derived from three-dimensional computed tomography reconstructions
    Arnold Radtke
    Department of General, Visceral and Transplantation Surgery, University Hospital Essen, Essen, Germany
    Transplantation 89:1518-25. 2010
    ..The knowledge of "venous dominance" is essential to prevent serious venous congestion in live donor liver transplantation and extended liver resections...
  71. ncbi request reprint Survival and recurrence rates after resection for hepatocellular carcinoma in noncirrhotic livers
    Hauke Lang
    Department of General Surgery, Visceral Surgery and Transplantation, University Hospital Essen, Essen, Germany
    J Am Coll Surg 205:27-36. 2007
    ..Hepatocellular carcinoma occurring in noncirrhotic livers is rare. The purpose of this article was to evaluate the outcomes and prognostic factors after hepatectomy in this setting...
  72. ncbi request reprint [Mesohepatectomy-an alternative to extended hepatectomy in the treatment of central liver tumors]
    H Lang
    Klinik für Allgemein und Transplantationschirurgie, Universitatsklinikum Essen
    Chirurg 75:424-9. 2004
    ..Mesohepatectomy should be considered in selected cases of central liver tumors in which extended resection would be associated with a high risk of liver insufficiency...
  73. ncbi request reprint [Surgical therapy of hepatocellular carcinoma]
    A Frilling
    Klinik für Allgemein und Transplantationschirurgie, Universitatsklinikum Essen
    Zentralbl Chir 128:900-5. 2003
    ..Living donor liver transplantation is a novel therapeutic option that improves posttransplant survival and extends the indication for transplantation in hepatocellular carcinoma...
  74. ncbi request reprint [Surgical therapy of intrahepatic cholangiocellular carcinoma]
    H Lang
    Klinik fUr Allgemein, Viszeral und Transplantationschirurgie, Universitatsklinikum Essen
    Chirurg 77:53-60. 2006
    ..Tumor resection is the treatment of choice, but so far the value of hepatic resection has not been well defined. We report results with an aggressive surgical approach for the treatment of this tumor entity...
  75. ncbi request reprint Benign esophagorespiratory fistula complicated by deep impaction of stent mesh in the esophageal wall
    H Lang
    Klinik für Allgemein und Transplantationschirurgie, Universitatsklinikum Essen, Germany
    Endoscopy 37:185-6. 2005
  76. ncbi request reprint Mesohepatectomy, caudate lobectomy and resection of hilar bifurcation with biliary reconstruction by 6 hepaticojejunostomies for Klatskin tumor
    Hauke Lang
    Department of General Surgery and Transplantation, University Hospital Essen, Germany
    Hepatogastroenterology 50:1327-9. 2003
    ..In these cases mesohepatectomy reduces the risk for postoperative liver insufficiency but still allows oncologic tumor resection...
  77. pmc Extended hepatectomy for intrahepatic cholangiocellular carcinoma (ICC): when is it worthwhile? Single center experience with 27 resections in 50 patients over a 5-year period
    Hauke Lang
    Department of General Surgery and Transplantation, University Hospital Essen, Hufelandstr 55, D 45122 Essen, Germany
    Ann Surg 241:134-43. 2005
    ..To evaluate the role of extended hepatectomy in locally advanced intrahepatic cholangiocarcinoma (ICC)...
  78. ncbi request reprint Living donor liver transplantation for hepatocellular carcinoma: a single-center preliminary report
    Massimo Malago
    Department of General Surgery and Transplantation, University Hospital Essen, Essen, Germany
    Liver Transpl 12:934-40. 2006
    ..In conclusion, LDLT is a promising treatment option for patients with HCC. Even longer follow-up and bigger patients' series are needed to fully assess the benefits of LDLT for HCC patients exceeding the Milan criteria...
  79. ncbi request reprint Liver transplantation for hepatocellular carcinoma and cirrhosis in candidates with undetectable or very low alpha-fetoprotein levels: is an expansion of the listing criteria justified?
    Georgios C Sotiropoulos
    Department of General, Visceral, and Transplantation Surgery, University Hospital Essen, Essen, Germany
    Hepatogastroenterology 55:1671-7. 2008
    ..The purpose of this study was to evaluate the results after LT for HCC patients with very low alpha fetoprotein (AFP) values both in our series and in literature reports...
  80. doi request reprint Computer-assisted surgery planning for complex liver resections: when is it helpful? A single-center experience over an 8-year period
    Arnold Radtke
    Department of General, Visceral and Transplantation Surgery, University Hospital Essen, Essen, Germany
    Ann Surg 252:876-83. 2010
    ..The purpose of this study was (1) to compare 2-dimensional computed tomographic (2D-CT) and 3D-CT computer-assisted preoperative surgical planning, and (2) to define the indications for the latter method...
  81. ncbi request reprint Impact of intraoperative radiotherapy (IORT) on survival of patients with unresectable hilar cholangiocarcinoma
    Gernot Maximilian Kaiser
    Department of General, Visceral and Transplantation Surgery, University Hospital Essen, Essen, Germany
    Hepatogastroenterology 55:1951-4. 2008
    ..The aim of this study was to compare the efficacy of IORT to surgery alone in patients with unresectable hilar cholangiocarcinoma...
  82. ncbi request reprint Left hepatic trisectionectomy for hepatobiliary malignancies
    Hauke Lang
    Department of General Surgery, Visceral Surgery and Transplantation, University Hospital of Essen, Essen, Germany
    J Am Coll Surg 203:311-21. 2006
    ..Left hepatic trisectionectomy is the most extended hepatic resection. To date, few data are available on longterm outcomes after this operation...
  83. ncbi request reprint Improved assessment of functional resectability in repeated hepatectomy by computer-assisted operation planning
    Hauke Lang
    Klinik für Allgemein und Transplantationschirurgie, Universitatsklinikum Essen, Germany
    Hepatogastroenterology 52:1645-8. 2005
    ....
  84. ncbi request reprint "Hepar divisum"--as a rare donor complication after intraoperative mortality of the recipient of an intended living donor liver transplantation
    Silvio Nadalin
    Department of General Surgery and Transplantation, University of Essen, Essen, Germany
    Liver Transpl 12:428-34. 2006
    ..The high incidence of biliary complication, however, is of concern. When more than 1 hepatic duct is present, the donor hepatectomy should be completed and the graft reallocated according to the policy of the transplant institution...
  85. ncbi request reprint Liver transplantation for patients with metastatic endocrine tumors: single-center experience with 15 patients
    Andrea Frilling
    Department of General, Visceral, and Transplantation Surgery, University Hospital Essen, Essen, Germany
    Liver Transpl 12:1089-96. 2006
    ....
  86. ncbi request reprint Contrast-enhanced multidetector-CT cholangiography after living donor liver transplantation
    Tobias Schroeder
    Department of Diagnostic and Interventional Radiology, University Hospital Essen, Germany
    Hepatogastroenterology 54:1176-80. 2007
    ..To prospectively evaluate the feasibility of postoperative contrast enhanced Multi-detector-CT cholangiography (ceMDCT-CA) in living liver donors and transplant recipients...
  87. ncbi request reprint Liver transplantation with "rescue organ offers" within the eurotransplant area: a 2-year report from the University Hospital Essen
    Georgios C Sotiropoulos
    Department of General, Visceral and Transplantation Surgery, University Hospital Essen, Germany
    Transplantation 82:304-9. 2006
    ..Overall patient survival was 84.4%. LTx with such "rescue organs" constitutes an additional transplant option and a safe mechanism to "rescue" organs within Eurotransplant...
  88. ncbi request reprint The influence of accessory right inferior hepatic veins on the venous drainage in right graft living donor liver transplantation
    Arnold Radtke
    Department of General Surgery and Transplantation, University Hospital Essen, Essen, Germany
    Hepatogastroenterology 53:479-83. 2006
    ....
  89. ncbi request reprint Liver transplantation for hepatocellular carcinoma in cirrhosis: is clinical tumor classification before transplantation realistic?
    Georgios C Sotiropoulos
    Department of General Surgery and Transplantation, University Hospital Essen, Hufelandstrasse 55, D 045122 Essen, Germany
    Transplantation 79:483-7. 2005
    ..The decision of whether to proceed with transplantation in patients with hepatocellular carcinoma (HCC) in cirrhosis is based on clinical and imaging findings. The purpose of our study was to evaluate the accuracy of the current system...
  90. ncbi request reprint Anatomical and physiological comparison of liver volumes among three frequent types of parenchyma transection in live donor liver transplantation
    Arnold Radtke
    Department of General Surgery and Transplantation, University Hospital Essen, Essen, Germany
    Hepatogastroenterology 52:333-8. 2005
    ..our study was to define and compare anatomical and physiological characteristics of venous drainage in the three most common types of liver transection techniques (Malagó, Cantlie, Pringle) encountered in live donor liver transplantation..
  91. ncbi request reprint Intraoperative application of "white test" to reduce postoperative bile leak after major liver resection: results of a prospective cohort study in 137 patients
    Jun Li
    Department of General, Visceral, and Transplant Surgery, University Hospital Essen, Essen, Germany
    Langenbecks Arch Surg 394:1019-24. 2009
    ..This study aimed to prove the clinical validation of the recently developed bile leakage test, "white test" (WT), in major liver resection...
  92. ncbi request reprint Liver transplantation in the setting of hepatocellular carcinoma and portal vein thrombosis: a challenging dilemma?
    Georgios C Sotiropoulos
    Department of General, Visceral and Transplantation Surgery, University Hospital Essen, Hufelandstr 55, Essen 45122, Germany
    Dig Dis Sci 53:1994-9. 2008
    ..However, it is frequently difficult to establish preoperatively whether the thrombus is associated with tumor invasion or with stagnant flow. The purpose of this study was to further address this controversial issue...
  93. doi request reprint Predictive factors of outcome in patients transplanted for hepatitis B
    Susanne Beckebaum
    Department of Gastroenterology and Hepatology, University Hospital Essen, Essen, Germany
    Transplantation 87:872-81. 2009
    ....
  94. ncbi request reprint Papillomatosis confined to the distal biliary tract--a rare cause of obstructive jaundice: report of a case
    Georgios C Sotiropoulos
    Department of General Surgery and Transplantation, University Hospital Essen, Hufelandstrasse 55, D 45122 Essen, Germany
    Surg Today 33:781-4. 2003
    ..When considering a radical resection, intraoperative cholangioscopy is strongly recommended to confirm any localized papillomatosis and rule out any diffuse papillomatosis of the entire biliary tract...
  95. ncbi request reprint Pulmonary and blood stream infections in adult living donor and cadaveric liver transplant patients
    Fuat H Saner
    Department of General, Visceral and Transplant Surgery, University Hospital Essen, Essen, Germany
    Transplantation 85:1564-8. 2008
    ..In the present cohort study, we compared the incidence and profiles of pulmonary and blood stream infections (BSI) between LDLT and CDLT recipients. We hypothesized a lower incidence in LDLT recipients...
  96. doi request reprint Assessment of allograft fibrosis by transient elastography and noninvasive biomarker scoring systems in liver transplant patients
    Susanne Beckebaum
    Department of General, Visceral, and Transplantation Surgery, University Hospital Essen, Essen, Germany
    Transplantation 89:983-93. 2010
    ....
  97. ncbi request reprint Resectability of hepatocellular carcinoma: evaluation of 333 consecutive cases at a single hepatobiliary specialty center and systematic review of the literature
    Georgios C Sotiropoulos
    Department of General Surgery and Transplantation, University Hospital Essen, Germany
    Hepatogastroenterology 53:322-9. 2006
    ..Liver resection constitutes a potentially curative treatment for HCC. However, because of the co-existing cirrhosis or the late diagnosis, only a percentage of the patients evaluated can undergo surgery...
  98. ncbi request reprint Split liver transplantation for hepatocellular carcinoma
    Georgios C Sotiropoulos
    Department of General, Visceral and Transplantation Surgery, University Hospital Essen, Germany
    Hepatogastroenterology 53:764-7. 2006
    ..However, because of limited organ availability, not all those who qualify can benefit from full-size LTx...
  99. doi request reprint Pulmonary nodules at risk in patients undergoing liver transplantation for hepatocellular carcinoma
    Georgios C Sotiropoulos
    Department of General, Visceral, and Transplantation Surgery, University Hospital Essen, Essen, Germany
    Transpl Int 21:850-6. 2008
    ..Small pulmonary nodules in high-risk HCC patients (low tumor grading, exceeding Milan criteria) may be characterized as nodules at risk, and evaluated very closely prior to listing and during the pre- and post-transplant periods...
  100. ncbi request reprint Jejunoduodenal fistula due to penetrating peptic ulcer after Roux-en-Y hepaticojejunostomy
    G C Sotiropoulos
    Dept of General Surgery and Transplantation, Essen University Hospital, Hufelandstrasse 55, 45122 Essen, Germany
    Endoscopy 35:549. 2003
  101. doi request reprint Survivin is upregulated during liver regeneration in rats and humans and is associated with hepatocyte proliferation
    Hideo A Baba
    Institute of Pathology and Neuropathology, University of Duisburg Essen, Essen, Germany
    Liver Int 29:585-92. 2009
    ..Survivin regulates cell division and inhibits apoptosis. Liver regeneration is a complex process involving both proliferation and apoptosis. The role of survivin is not well elucidated and no data exist in humans...