Peter Soba

Summary

Affiliation: University of Heidelberg
Country: Germany

Publications

  1. pmc Homo- and heterodimerization of APP family members promotes intercellular adhesion
    Peter Soba
    ZMBH, University of Heidelberg, Heidelberg, Germany
    EMBO J 24:3624-34. 2005
  2. pmc Interference of human and Drosophila APP and APP-like proteins with PNS development in Drosophila
    Gunter Merdes
    ZMBH, University of Heidelberg, Heidelberg, Germany
    EMBO J 23:4082-95. 2004
  3. ncbi request reprint PAT1a modulates intracellular transport and processing of amyloid precursor protein (APP), APLP1, and APLP2
    Yung Hui Kuan
    Zentrum für Molekulare Biologie ZMBH, University of Heidelberg, D 69120 Heidelberg, Germany
    J Biol Chem 281:40114-23. 2006
  4. ncbi request reprint The proteolytic processing of the amyloid precursor protein gene family members APLP-1 and APLP-2 involves alpha-, beta-, gamma-, and epsilon-like cleavages: modulation of APLP-1 processing by n-glycosylation
    Simone Eggert
    Zentrum für Molekulare Biologie Heidelberg, ZMBH, INF 282, 69120 Heidelberg, Germany
    J Biol Chem 279:18146-56. 2004
  5. pmc Cell-type-specific processing of the amyloid precursor protein by Presenilin during Drosophila development
    Alexander Loewer
    ZMBH, University of Heidelberg, INF 282, 69120 Heidelberg, Germany
    EMBO Rep 5:405-11. 2004
  6. ncbi request reprint Axonal accumulation of synaptic markers in APP transgenic Drosophila depends on the NPTY motif and is paralleled by defects in synaptic plasticity
    Patricia Rusu
    Zentrum für Molekulare Biologie ZMBH, Im Neuenheimer Feld 282, 69120 Heidelberg, Germany
    Eur J Neurosci 25:1079-86. 2007
  7. pmc Drosophila sensory neurons require Dscam for dendritic self-avoidance and proper dendritic field organization
    Peter Soba
    Howard Hughes Medical Institute, Department of Physiology, University of California, San Francisco, Rock Hall, 1550 4th Street, San Francisco, CA 94143, USA
    Neuron 54:403-16. 2007

Collaborators

Detail Information

Publications7

  1. pmc Homo- and heterodimerization of APP family members promotes intercellular adhesion
    Peter Soba
    ZMBH, University of Heidelberg, Heidelberg, Germany
    EMBO J 24:3624-34. 2005
    ..Together, our results provide evidence that homo- and heterocomplexes of APP/APLPs promote trans-cellular adhesion in vivo...
  2. pmc Interference of human and Drosophila APP and APP-like proteins with PNS development in Drosophila
    Gunter Merdes
    ZMBH, University of Heidelberg, Heidelberg, Germany
    EMBO J 23:4082-95. 2004
    ....
  3. ncbi request reprint PAT1a modulates intracellular transport and processing of amyloid precursor protein (APP), APLP1, and APLP2
    Yung Hui Kuan
    Zentrum für Molekulare Biologie ZMBH, University of Heidelberg, D 69120 Heidelberg, Germany
    J Biol Chem 281:40114-23. 2006
    ..Finally, we show that PAT1a promotes APP/APLPs processing, resulting in increased secretion of beta-amyloid peptide. Taken together, our data establish PAT1a as a functional link between APP/APLPs transport and their processing...
  4. ncbi request reprint The proteolytic processing of the amyloid precursor protein gene family members APLP-1 and APLP-2 involves alpha-, beta-, gamma-, and epsilon-like cleavages: modulation of APLP-1 processing by n-glycosylation
    Simone Eggert
    Zentrum für Molekulare Biologie Heidelberg, ZMBH, INF 282, 69120 Heidelberg, Germany
    J Biol Chem 279:18146-56. 2004
    ..Additionally, we were able to detect p3-like fragments of APLP-1 and p3-like and Abeta-like fragments of APLP-2 in the media of stably transfected SH-SY5Y cells...
  5. pmc Cell-type-specific processing of the amyloid precursor protein by Presenilin during Drosophila development
    Alexander Loewer
    ZMBH, University of Heidelberg, INF 282, 69120 Heidelberg, Germany
    EMBO Rep 5:405-11. 2004
    ..Using this system, we demonstrate differences between APP and Notch processing and show that PS-mediated cleavage of APP can be regulated in different cell types independent of the size of the extracellular domain...
  6. ncbi request reprint Axonal accumulation of synaptic markers in APP transgenic Drosophila depends on the NPTY motif and is paralleled by defects in synaptic plasticity
    Patricia Rusu
    Zentrum für Molekulare Biologie ZMBH, Im Neuenheimer Feld 282, 69120 Heidelberg, Germany
    Eur J Neurosci 25:1079-86. 2007
    ....
  7. pmc Drosophila sensory neurons require Dscam for dendritic self-avoidance and proper dendritic field organization
    Peter Soba
    Howard Hughes Medical Institute, Department of Physiology, University of California, San Francisco, Rock Hall, 1550 4th Street, San Francisco, CA 94143, USA
    Neuron 54:403-16. 2007
    ....