Manuela Simonetti

Summary

Affiliation: University of Heidelberg
Country: Germany

Publications

  1. pmc Mutated CaV2.1 channels dysregulate CASK/P2X3 signaling in mouse trigeminal sensory neurons of R192Q Cacna1a knock-in mice
    Aswini Gnanasekaran
    Neuroscience Department, International School for Advanced Studies SISSA, via Bonomea 265, Trieste 34136, Italy
    Mol Pain 9:62. 2013
  2. doi request reprint Wnt-Fzd signaling sensitizes peripheral sensory neurons via distinct noncanonical pathways
    Manuela Simonetti
    Institute for Pharmacology, University of Heidelberg, Im Neuenheimer Feld 366, 69120 Heidelberg, Germany Molecular Medicine Partnership Unit, Otto Meyerhof Center, Im Neuenheimer Feld, 69120 Heidelberg, Germany Electronic address
    Neuron 83:104-21. 2014
  3. pmc Familial hemiplegic migraine Ca(v)2.1 channel mutation R192Q enhances ATP-gated P2X3 receptor activity of mouse sensory ganglion neurons mediating trigeminal pain
    Asha Nair
    Neurobiology Sector, International School for Advanced Studies SISSA, via Bonomea 265, 34136 Trieste, Italy
    Mol Pain 6:48. 2010

Collaborators

  • Aswini Gnanasekaran
  • Elsa Fabbretti
  • Andrea Nistri
  • Arn M J M van den Maagdenberg
  • Asha Nair
  • Swathi Hullugundi
  • Tanja Bele
  • Michael D Ferrari
  • Nicol Birsa
  • Rashid Giniatullin
  • Michel D Ferrari

Detail Information

Publications3

  1. pmc Mutated CaV2.1 channels dysregulate CASK/P2X3 signaling in mouse trigeminal sensory neurons of R192Q Cacna1a knock-in mice
    Aswini Gnanasekaran
    Neuroscience Department, International School for Advanced Studies SISSA, via Bonomea 265, Trieste 34136, Italy
    Mol Pain 9:62. 2013
    ....
  2. doi request reprint Wnt-Fzd signaling sensitizes peripheral sensory neurons via distinct noncanonical pathways
    Manuela Simonetti
    Institute for Pharmacology, University of Heidelberg, Im Neuenheimer Feld 366, 69120 Heidelberg, Germany Molecular Medicine Partnership Unit, Otto Meyerhof Center, Im Neuenheimer Feld, 69120 Heidelberg, Germany Electronic address
    Neuron 83:104-21. 2014
    ..Finally, this study provides proof-of-concept for a translational potential for Wnt3a-Frizzled3 signaling in alleviating disease-related pain hypersensitivity in cancer-associated pain in vivo. ..
  3. pmc Familial hemiplegic migraine Ca(v)2.1 channel mutation R192Q enhances ATP-gated P2X3 receptor activity of mouse sensory ganglion neurons mediating trigeminal pain
    Asha Nair
    Neurobiology Sector, International School for Advanced Studies SISSA, via Bonomea 265, 34136 Trieste, Italy
    Mol Pain 6:48. 2010
    ..We investigated whether this gain-of-function mutation changed the structure and function of trigeminal neuron P2X3 receptors that are thought to be important contributors to migraine pain...