Manuela Simonetti

Summary

Affiliation: University of Heidelberg
Country: Germany

Publications

  1. ncbi request reprint Wnt-Fzd Signaling Sensitizes Peripheral Sensory Neurons via Distinct Noncanonical Pathways
    Manuela Simonetti
    Institute for Pharmacology, University of Heidelberg, Im Neuenheimer Feld 366, 69120 Heidelberg, Germany Molecular Medicine Partnership Unit, Otto Meyerhof Center, Im Neuenheimer Feld, 69120 Heidelberg, Germany Electronic address
    Neuron 83:104-21. 2014
  2. pmc Familial hemiplegic migraine Ca(v)2.1 channel mutation R192Q enhances ATP-gated P2X3 receptor activity of mouse sensory ganglion neurons mediating trigeminal pain
    Asha Nair
    Neurobiology Sector, International School for Advanced Studies SISSA, via Bonomea 265, 34136 Trieste, Italy
    Mol Pain 6:48. 2010

Collaborators

  • Asha Nair
  • Nicol Birsa
  • Arn M J M van den Maagdenberg
  • Andrea Nistri
  • Rashid Giniatullin
  • Michel D Ferrari
  • Elsa Fabbretti

Detail Information

Publications2

  1. ncbi request reprint Wnt-Fzd Signaling Sensitizes Peripheral Sensory Neurons via Distinct Noncanonical Pathways
    Manuela Simonetti
    Institute for Pharmacology, University of Heidelberg, Im Neuenheimer Feld 366, 69120 Heidelberg, Germany Molecular Medicine Partnership Unit, Otto Meyerhof Center, Im Neuenheimer Feld, 69120 Heidelberg, Germany Electronic address
    Neuron 83:104-21. 2014
    ..Finally, this study provides proof-of-concept for a translational potential for Wnt3a-Frizzled3 signaling in alleviating disease-related pain hypersensitivity in cancer-associated pain in vivo. ..
  2. pmc Familial hemiplegic migraine Ca(v)2.1 channel mutation R192Q enhances ATP-gated P2X3 receptor activity of mouse sensory ganglion neurons mediating trigeminal pain
    Asha Nair
    Neurobiology Sector, International School for Advanced Studies SISSA, via Bonomea 265, 34136 Trieste, Italy
    Mol Pain 6:48. 2010
    ..We investigated whether this gain-of-function mutation changed the structure and function of trigeminal neuron P2X3 receptors that are thought to be important contributors to migraine pain...