Myrtill Simko

Summary

Affiliation: University of Rostock
Country: Germany

Publications

  1. ncbi request reprint Effects of 50 Hz EMF exposure on micronucleus formation and apoptosis in transformed and nontransformed human cell lines
    M Simko
    Institute of Animal Physiology, Unit of Environmental Physiology, University of Rostock, Germany
    Bioelectromagnetics 19:85-91. 1998
  2. ncbi request reprint Induction of cell activation processes by low frequency electromagnetic fields
    Myrtill Simko
    University of Rostock, Institute of Cell Biology and Biosystems Technology, Division of Environmental Physiology, Albert Einstein Str 3, D 18059 Rostock, Germany
    ScientificWorldJournal 4:4-22. 2004
  3. ncbi request reprint Extremely low frequency electromagnetic fields as effectors of cellular responses in vitro: possible immune cell activation
    Myrtill Simko
    Division of Environmental Physiology, Institute of Cell Biology and Biosystems Technology, University of Rostock, Albert Einstein Strasse 3, D 18059 Rostock, Germany
    J Cell Biochem 93:83-92. 2004
  4. ncbi request reprint Stimulation of phagocytosis and free radical production in murine macrophages by 50 Hz electromagnetic fields
    M Simko
    University of Rostock, Institute of Cell Biology and Biosystems Technology, Division of Environmental Physiology, Germany
    Eur J Cell Biol 80:562-6. 2001
  5. ncbi request reprint Micronucleus induction in Syrian hamster embryo cells following exposure to 50 Hz magnetic fields, benzo(a)pyrene, and TPA in vitro
    M Simko
    Division of Environmental Physiology, Institute of Cell Biology and Biosystems Technology, University of Rostock, Universitatsplatz 2, D 18051 Rostock, Germany
    Mutat Res 495:43-50. 2001
  6. ncbi request reprint Absence of synergistic effects on micronucleus formation after exposure to electromagnetic fields and asbestos fibers in vitro
    M Simko
    Division of Environmental Physiology, Institute of Cellular Physiology and Biosystems Technology, University of Rostock, Germany
    Toxicol Lett 108:47-53. 1999
  7. ncbi request reprint Micronucleus formation in human amnion cells after exposure to 50 Hz MF applied horizontally and vertically
    M Simko
    Institute of Animal Physiology, Division of Environmental Physiology, University of Rostock, Universitatsplatz 2, D 18055, Rostock, Germany
    Mutat Res 418:101-11. 1998
  8. ncbi request reprint Cell activating capacity of 50 Hz magnetic fields to release reactive oxygen intermediates in human umbilical cord blood-derived monocytes and in Mono Mac 6 cells
    Madeleine Lupke
    University of Rostock, Institute of Cell Biology and Biosystems Technology, Division of Environmental Physiology, Albert Einstein Str 3, D 18059 Rostock, Germany
    Free Radic Res 38:985-93. 2004
  9. ncbi request reprint Alteration in cellular functions in mouse macrophages after exposure to 50 Hz magnetic fields
    Jana Frahm
    Department of Cell Biology and Biosystems Technology, Unit of Environmental Physiology, University of Rostock, Albert Einstein Strasse 3 D 18057 Rostock, Germany
    J Cell Biochem 99:168-77. 2006
  10. ncbi request reprint Fifty-hertz magnetic fields induce free radical formation in mouse bone marrow-derived promonocytes and macrophages
    Jana Rollwitz
    Division of Environmental Physiology, Institute for Cell Biology and Biosystems Technology, University of Rostock, Albert Einstein Strasse 3, D 18057 Rostock, Germany
    Biochim Biophys Acta 1674:231-8. 2004

Collaborators

Detail Information

Publications15

  1. ncbi request reprint Effects of 50 Hz EMF exposure on micronucleus formation and apoptosis in transformed and nontransformed human cell lines
    M Simko
    Institute of Animal Physiology, Unit of Environmental Physiology, University of Rostock, Germany
    Bioelectromagnetics 19:85-91. 1998
    ..These findings suggest that EMF could be a promotor but not an initiator of carcinogenic effects...
  2. ncbi request reprint Induction of cell activation processes by low frequency electromagnetic fields
    Myrtill Simko
    University of Rostock, Institute of Cell Biology and Biosystems Technology, Division of Environmental Physiology, Albert Einstein Str 3, D 18059 Rostock, Germany
    ScientificWorldJournal 4:4-22. 2004
    ..To demonstrate a possible interaction between EMF and cellular systems, we present a mechanistic model describing cell activation as a major importance for cellular response...
  3. ncbi request reprint Extremely low frequency electromagnetic fields as effectors of cellular responses in vitro: possible immune cell activation
    Myrtill Simko
    Division of Environmental Physiology, Institute of Cell Biology and Biosystems Technology, University of Rostock, Albert Einstein Strasse 3, D 18059 Rostock, Germany
    J Cell Biochem 93:83-92. 2004
    ....
  4. ncbi request reprint Stimulation of phagocytosis and free radical production in murine macrophages by 50 Hz electromagnetic fields
    M Simko
    University of Rostock, Institute of Cell Biology and Biosystems Technology, Division of Environmental Physiology, Germany
    Eur J Cell Biol 80:562-6. 2001
    ..Furthermore, a significant increased superoxide production after exposure to electromagnetic fields was detected...
  5. ncbi request reprint Micronucleus induction in Syrian hamster embryo cells following exposure to 50 Hz magnetic fields, benzo(a)pyrene, and TPA in vitro
    M Simko
    Division of Environmental Physiology, Institute of Cell Biology and Biosystems Technology, University of Rostock, Universitatsplatz 2, D 18051 Rostock, Germany
    Mutat Res 495:43-50. 2001
    ..The resulting genomic instability is proposed to be due to free radicals and/or to the unscheduled "switching-on" of signal transduction pathways...
  6. ncbi request reprint Absence of synergistic effects on micronucleus formation after exposure to electromagnetic fields and asbestos fibers in vitro
    M Simko
    Division of Environmental Physiology, Institute of Cellular Physiology and Biosystems Technology, University of Rostock, Germany
    Toxicol Lett 108:47-53. 1999
    ..The results indicate, that under our experimental conditions, exposure to hMF and treatment with asbestos fibers possess genotoxic capability, but no interactive effects, in AFC cells...
  7. ncbi request reprint Micronucleus formation in human amnion cells after exposure to 50 Hz MF applied horizontally and vertically
    M Simko
    Institute of Animal Physiology, Division of Environmental Physiology, University of Rostock, Universitatsplatz 2, D 18055, Rostock, Germany
    Mutat Res 418:101-11. 1998
    ..Therefore, the reason for inconsistent results published in the literature may be caused by the variability of exposure systems, the exposure conditions and the cell types used...
  8. ncbi request reprint Cell activating capacity of 50 Hz magnetic fields to release reactive oxygen intermediates in human umbilical cord blood-derived monocytes and in Mono Mac 6 cells
    Madeleine Lupke
    University of Rostock, Institute of Cell Biology and Biosystems Technology, Division of Environmental Physiology, Albert Einstein Str 3, D 18059 Rostock, Germany
    Free Radic Res 38:985-93. 2004
    ..Therefore, we suggest that ELF-MF exposure induces the activation of NADH oxidase in these cells. However, the MF-effect was inhibited by DPI in monocytes, indicating the activation of the NADPH oxidase after exposure to ELF-MF...
  9. ncbi request reprint Alteration in cellular functions in mouse macrophages after exposure to 50 Hz magnetic fields
    Jana Frahm
    Department of Cell Biology and Biosystems Technology, Unit of Environmental Physiology, University of Rostock, Albert Einstein Strasse 3 D 18057 Rostock, Germany
    J Cell Biochem 99:168-77. 2006
    ....
  10. ncbi request reprint Fifty-hertz magnetic fields induce free radical formation in mouse bone marrow-derived promonocytes and macrophages
    Jana Rollwitz
    Division of Environmental Physiology, Institute for Cell Biology and Biosystems Technology, University of Rostock, Albert Einstein Strasse 3, D 18057 Rostock, Germany
    Biochim Biophys Acta 1674:231-8. 2004
    ..Furthermore, we showed an oscillation (1-10 days) in superoxide anion radical release in mouse macrophages, indicating a cyclic pattern of NADH-oxidase activity...
  11. doi request reprint Exposure to ELF magnetic fields modulate redox related protein expression in mouse macrophages
    Jana Frahm
    Division of Environmental Physiology, Department of Cell Biology and Biosystems Technology, University of Rostock, Rostock, Germany
    Toxicol Lett 192:330-6. 2010
    ..This suggests that ELF MF interacts with other cellular constituents than these chemicals, although induced pathways at least partially converge...
  12. ncbi request reprint Alterations in the cell cycle and in the protein level of cyclin D1, p21CIP1, and p16INK4a after exposure to 50 Hz MF in human cells
    Sandra Lange
    University of Rostock, Institute of Cell Biology and Biosystems Technology, Division of Environmental Physiology, Albert Einstein Strasse 3, 18059 Rostock, Germany
    Radiat Environ Biophys 41:131-7. 2002
    ..Reduced levels of both Cdk inhibitors were observed at longer exposure times (24 h, 30 h). Our results suggest an inhibitory effect of MF on the G1-phase induced by altered expression of p16INK4a and p21CIP1...
  13. ncbi request reprint Cytotoxicity, genotoxicity and intracellular distribution of the Auger electron emitter (65)Zn in two human cell lines
    Ralf Kriehuber
    Institute of Cell Biology and Biosystems TechnologyDepartment of Biological Sciences, University of Rostock, Albert Einstein Strasse 3, 18051, Rostock, Germany
    Radiat Environ Biophys 43:15-22. 2004
    ....
  14. ncbi request reprint Gene expression analysis of ELF-MF exposed human monocytes indicating the involvement of the alternative activation pathway
    Madeleine Lupke
    Division of Environmental Physiology, Institute of Cell Biology and Biosystems Technology, University of Rostock, Albert Einstein Str 3, D 18059 Rostock, Germany
    Biochim Biophys Acta 1763:402-12. 2006
    ..Accordingly, we suggest that ELF-MF activates human monocytes via the alternative pathway...
  15. ncbi request reprint Cell type specific redox status is responsible for diverse electromagnetic field effects
    Myrtill Simko
    Division of Environmental Physiology, Department of Cell Biology and Biosystems Technology, University of Rostock, D 18059 Rostock, Germany
    Curr Med Chem 14:1141-52. 2007
    ..Finally, we conclude from our review that modulations on the oxidant and antioxidant level through ELF-EMF exposure can play a causal role in cancer development...