Research Topics
| Shailesh V ShrikhandeSummaryAffiliation: University of Heidelberg Country: Germany Publications
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Detail Information
Publications
D2 lymphadenectomy for gastric cancer in Tata Memorial Hospital: Indian data can now be incorporated in future international trialsShailesh V Shrikhande
Department of Gastrointestinal Surgical Oncology, Tata Memorial Hospital, Mumbai, India
Dig Surg 23:192-7. 2006..While mortality rates after radical gastrectomy have decreased, there is considerable morbidity after D2 lymphadenectomy. In this study, we assessed the perioperative results of D2 gastrectomy for gastric cancer...
Pancreatic fistula after pancreaticoduodenectomy: the impact of a standardized technique of pancreaticojejunostomyShailesh V Shrikhande
Gastrointestinal Surgical Oncology, Tata Memorial Hospital, Ernest Borges Marg, Parel, Mumbai 400 012, India
Langenbecks Arch Surg 393:87-91. 2008..The role of standardization on outcomes after pancreaticoduodenectomy has not been sufficiently addressed...
Superior mesenteric artery first combined with uncinate process approach versus uncinate process first approach in pancreatoduodenectomy: a comparative study evaluating perioperative outcomesShailesh V Shrikhande
Department of Gastrointestinal and Hepato Pancreato Biliary Surgery, Tata Memorial Hospital, Mumbai, India
Langenbecks Arch Surg 396:1205-12. 2011..During pancreatoduodenectomy (PD), two techniques have been described to dissect the head of pancreas, viz. the superior mesenteric artery (SMA) approach by dissecting the uncinate process and the uncinate process first approach...
Borderline resectable pancreatic tumors: is there a need for further refinement of this stage?Shailesh V Shrikhande
Department of Hepato Pancreato Biliary Surgical Oncology, Tata Memorial Hospital, Mumbai, India
Hepatobiliary Pancreat Dis Int 10:319-24. 2011..The aim of the present study was to identify specific findings on preoperative imaging that could help predict in which patients with BRT a complete resection, with or without vascular resection (VR), could be achieved...
A new scoring system for gallbladder cancer (aiding treatment algorithm): an analysis of 335 patientsParul J Shukla
Department of Gastrointestinal Surgical Oncology, Tata Memorial Hospital, Parel, Mumbai 400 012, India
Ann Surg Oncol 15:3132-7. 2008..We thus sought to validate a new scoring system, the Tata Memorial Hospital Staging System (TMHSS), for gallbladder cancer...
Gastrointestinal stromal tumors: case series of 29 patients defining the role of imatinib prior to surgeryShailesh V Shrikhande
Department of Gastrointestinal and HPB Surgical Oncology, Tata Memorial Hospital, Ernest Borges Marg, Parel, Mumbai, 400012, Maharashtra, India
World J Surg 36:864-71. 2012..The aim of this study was to assess the role of neoadjuvant imatinib in redefining treatment for gastrointestinal stromal tumors (GISTs)...
Complications as indicators of quality assurance after 401 consecutive colorectal cancer resections: the importance of surgeon volume in developing colorectal cancer units in IndiaGuruprasad S Shetty
Department of Gastrointestinal Surgical Oncology, Tata Memorial Centre, Mumbai, India
World J Surg Oncol 10:15. 2012..We evaluated the data of the senior author to better define the requirements that would enable development of specialized units in a country where colorectal cancer burden is increasing...
Hepatoblastoma: a single institutional experience of 18 casesParul J Shukla
Department of Gastrointestinal Surgical Oncology, Tata Memorial Hospital, Parel, Mumbai 400 012, India
Pediatr Surg Int 24:799-802. 2008....
The vascular stapler in uncinate process division during pancreaticoduodenectomy: technical considerations and resultsMelroy A D'souza
Department of GI and HPB Surgical Oncology, Tata Memorial Hospital, Mumbai, India
Dig Surg 27:175-81. 2010..Our aim is to discuss our technique and the peri-operative outcomes with the use of the linear vascular stapler for division of the uncinate process during PD...
Managing leaks following anterior resections: a new classification systemParul J Shukla
Tata Memorial Hospital, Mumbai, India
Hepatogastroenterology 58:1095-8. 2011..3%. The aim of our study was to identify those patients who had developed an anastomotic leak, and evaluate the indications for re-exploration as well as study the impact of covering colostomies on the subsequent outcome...
Postoperative deep vein thrombosis in patients with colorectal cancerParul J Shukla
Department of Gastrointestinal and Hepatopancreatobiliary Surgical Oncology, Tata Memorial Hospital, Mumbai, India
Indian J Gastroenterol 27:71-3. 2008..No episode of DVT occurred in either the drug arm or the observation arm. There was no death following surgery. The incidence of DVT in Indian patients operated for colorectal cancer in the lithotomy position was negligible...
The gray zone between postpancreaticoduodenectomy collections and pancreatic fistulaGeorge Barreto
Department of Gastrointestinal and Hepatopancreatobiliary Surgical Oncology, Tata Memorial Hospital, Mumbai, India
Pancreas 37:422-5. 2008..There is a recent report questioning the ISGPF criteria's ability to accurately predict pancreatic anastomotic failure and outlining new criteria. We decided to validate both proposed criteria based on our experience...
Three cases of unusual solid pseudopapillary tumors. Can radiology and histology aid decision-making?Soheil Shaikh
Department of Gastrointestinal Surgical Oncology, Tata Memorial Hospital Mumbai, India
JOP 9:150-9. 2008..The tendency of some of these tumors to be locally aggressive and also to metastasize has been well recognized. It is not possible to predict the biologic behavior of these tumors based only on their morphology...
Pancreatic resection for M1 pancreatic ductal adenocarcinomaShailesh V Shrikhande
Department of Gastrointestinal Surgical Oncology, Tata Memorial Hospital, Ernest Borges Marg, Parel, Mumbai, 400012, India
Ann Surg Oncol 14:118-27. 2007..Improved safety of pancreatic surgery has led to consideration of more aggressive approaches, such as resection for primary pancreatic ductal adenocarcinoma (PDAC) with metastatic disease (M1)...
Surgery for gastric cancer: an evidence-based perspectiveMelroy A D'souza
Department of GI and HPB Surgical Oncology, Tata Memorial Hospital, Parel, Mumbai, India
J Cancer Res Ther 5:225-31. 2009..The search has been limited to English publications on human subjects. A manual search of the bibliographies has also been carried out, to identify the relevant publications for possible inclusion...
Outcomes of resection for rectal cancer in India: the impact of the double stapling techniqueShailesh V Shrikhande
Gastrointestinal Surgical Oncology, Tata Memorial Hospital, Mumbai, India
World J Surg Oncol 5:35. 2007..However studies using this technique and their results, in the Indian scenario, as well as the rest of Asia, have been few and far between...
Feasibility of laparoscopic abdomino-perineal resection for large-sized anorectal cancers: a single-institution experience of 59 casesParul J Shukla
Department of Gastrointestinal Surgical Oncology, Tata Memorial Hospital, Mumbai, India
Indian J Med Sci 63:109-14. 2009..Laparoscopic surgery for anorectal carcinoma is steadily gaining acceptance. While feasibility has already been reported, there are no reports addressing the impact of the actual size of large tumors on laparoscopic resectability...
Neurokinin-1 receptor expression and its potential effects on tumor growth in human pancreatic cancerHelmut Friess
Department of General Surgery, University of Heidelberg, Germany
Lab Invest 83:731-42. 2003..These findings illustrate that the NK-1R pathway is activated in human pancreatic cancer and has the potential to contribute to cancer cell growth, thus suggesting the existence of a neuro-cancer cell interaction in vivo...
Multimodality imaging of pancreatic ductal adenocarcinoma: a review of the literatureShailesh V Shrikhande
Departments of Hepato Pancreato Biliary Surgical Oncology Radiology, Tata Memorial Hospital, Mumbai, India
HPB (Oxford) 14:658-68. 2012..This review aimed to determine the role of current imaging modalities in the diagnosis and determination of resectability of pancreatic and peri-ampullary adenocarcinomas...
Pancreatic anastomoses after pancreaticoduodenectomy: do we need further studies?Shailesh V Shrikhande
Department of Gastrointestinal Surgical Oncology, Tata Memorial Hospital, Dr Ernest Borges Marg, Parel, Mumbai, 400 012, India
World J Surg 29:1642-9. 2005....
Can we do better than 'incidental' gallbladder cancer?Parul J Shukla
Department of Gastrointestinal and Hepatopancreatobiliary Surgical Oncology, Tata Memorial Hospital, Mumbai, India
Hepatogastroenterology 54:2184-5. 2007....
The evolution of pancreatoduodenectomyParul J Shukla
Department of Gastointestinal and Hepato Pancreato Biliary Surgical Oncology, Tata Memorial Hospital, Mumbai, India
Hepatogastroenterology 58:1409-12. 2011..This review aims at highlighting the important milestones in the history of pancreatoduodenectomy leading to its progressive development, whilst providing a scientific basis...
Reoperative pancreaticoduodenectomy for periampullary carcinomaParul J Shukla
Department of Gastrointestinal Surgery, Tata Memorial Hospital, Parel, Bombay, India
ANZ J Surg 75:520-3. 2005..The purpose of the present paper was to determine the perioperative morbidity and mortality for patients undergoing reoperative pancreaticoduodenectomy at a major comprehensive cancer centre...
Isolated gall bladder metastasis from renal cell carcinomaDurgatosh Pandey
Department of Surgical Oncology, Tata Memorial Hospital, Mumbai - 400 012, India
Indian J Gastroenterol 25:161-2. 2006..He underwent cholecystectomy and frozen section revealed the metastatic tumor. Sixteen months later, the patient is free of disease...
Pancreatic resectional surgery: an evidence-based perspectiveMelroy A D'souza
Department of Gastrointestinal and Hepato Pancreato Biliary Surgical Oncology, Tata Memorial Hospital, Mumbai, India
J Cancer Res Ther 4:77-83. 2008..The search was limited to English language publications on human subjects. A manual cross-reference search of the bibliographies of relevant papers was carried out to identify publications for possible inclusion...
Impact of intra-operative ultrasonography in liver surgeryParul J Shukla
Department of GI Surgical Oncology, Tata Memorial Hospital, Mumbai
Indian J Gastroenterol 24:62-5. 2005..We assessed the impact of IOUS in liver surgery at our hospital, a tertiary-care cancer center...
Hepatic resection for metastasis from adenoid cystic carcinoma of parotid glandSajid S Qureshi
Department of Surgical Gastroenterology, Tata Memorial Hospital, Mumbai-400 012, India
Indian J Gastroenterol 24:29-30. 2005..We present a 30-year-old woman with solitary liver metastasis from an adenoid cystic carcinoma of the parotid gland, which had been surgically treated 10 years ago. The patient underwent successful resection of this metastasis...
Extended pancreatic resections and lymphadenectomy: An appraisal of the current evidenceShailesh V Shrikhande
Shailesh V Shrikhande, Department of Hepato Pancreato Biliary Surgical Oncology, Tata Memorial Hospital, Mumbai 400 012, India
World J Gastrointest Surg 2:39-46. 2010..This article revisits the data from such studies in an attempt to determine if the available literature supports the performance of extended resections for pancreatic cancer in terms of improvement of survival...
Surgery for gallbladder cancer: The need to generate greater evidenceShailesh V Shrikhande
Shailesh V Shrikhande, Department of Gastrointestinal Surgical Oncology, Tata Memorial Hospital, Mumbai 400012, India
World J Gastrointest Surg 1:26-9. 2009....
Is early feeding after major gastrointestinal surgery a fashion or an advance? Evidence-based review of literatureShailesh V Shrikhande
Department of Gastrointestinal and Hepato Pancreato Biliary Surgery, Tata Memorial Hospital, Mumbai, India
J Cancer Res Ther 5:232-9. 2009..Early enteral immunonutrition should be used only in malnourished and in transfused patients. Early EN after major digestive surgery is an old advance that is now in fashion...
Primary neuroendocrine carcinoma presenting as mesenteric cystAjay S Punpale
Department of Gastrointestinal Surgical Oncology, Tata Memorial Hospital, Mumbai, India
Indian J Gastroenterol 26:137-8. 2007..Surgical resection is the best treatment modality, with a chance of cure. We present a 65-year-old man with large mesenteric cyst and absence of bowel involvement. Histology showed a well-differentiated neuroendocrine tumor...
Small intestinal tumoursSavio George Barreto
Department of Gastrointestinal Surgical Oncology, Tata Memorial Hospital, Mumbai, India
J Coll Physicians Surg Pak 19:459-63. 2009..Small bowel consciousness is crucial in diagnosing and treating these tumours. This review aims to increase awareness of small bowel tumours in terms of epidemiology, diagnosis and treatment...
Modified technique of gasless laparoscopic cholecystectomy in a developing country: a 5-year experienceAnand G Nande
Department of Surgery, Shrikhande Clinic, Mumbai, India
Dig Surg 19:366-71; discussion 372. 2002..It probably costs less and is therefore more useful in developing countries. However, it has limitation in overweight patients who are infrequently encountered in our population...
Silencing of X-linked inhibitor of apoptosis (XIAP) decreases gemcitabine resistance of pancreatic cancer cellsShailesh V Shrikhande
Department of General Surgery, University of Heidelberg, Heidelberg, Germany
Anticancer Res 26:3265-73. 2006..It confers resistance to apoptosis induction by chemotherapeutic agents. The aim of this study was to evaluate the influence of XIAP in pancreatic cancer...
Vitamin D3 in operable periampullary and pancreatic cancer: perioperative outcomes in a pilot study assessing safetySavio G Barreto
Pancreas 36:315-7. 2008
Detection of gall bladder cancer metastases in rare sites by PET scanParul J Shukla
Indian J Gastroenterol 26:303-4. 2007
