Gunter Schwarz

Summary

Affiliation: University of Cologne
Country: Germany

Publications

  1. doi request reprint Structural basis of thermal stability of the tungsten cofactor synthesis protein MoaB from Pyrococcus furiosus
    Nastassia Havarushka
    Institute of Biochemistry, Department of Chemistry, University of Cologne, Cologne, Germany
    PLoS ONE 9:e86030. 2014
  2. doi request reprint S-palmitoylation represents a novel mechanism regulating the mitochondrial targeting of BAX and initiation of apoptosis
    M Frohlich
    Institute of Biochemistry, Department of Chemistry and Center for Molecular Medicine, Cologne University, Zulpicher Strasse 47, Cologne 50674, Germany
    Cell Death Dis 5:e1057. 2014
  3. ncbi request reprint Molybdenum in human health and disease
    Guenter Schwarz
    Institute of Biochemistry, Department of Chemistry, Center for Molecular Medicine, University of Cologne, Zulpicher Strasse 47, D 50674, Koln, Germany
    Met Ions Life Sci 13:415-50. 2013
  4. ncbi request reprint Molybdenum cofactor biosynthesis and molybdenum enzymes
    Gunter Schwarz
    Institute of Plant Biology, Technical University Braunschweig, 38023 Braunschweig, Germany
    Annu Rev Plant Biol 57:623-47. 2006
  5. doi request reprint Molybdenum cofactors, enzymes and pathways
    Gunter Schwarz
    Institute of Biochemistry, Department of Chemistry and Centre for Molecular Medicine, University of Cologne, 47 Zuelpicher Street, 50674 Cologne, Germany
    Nature 460:839-47. 2009
  6. doi request reprint Multivalent interactions of the SUMO-interaction motifs in RING finger protein 4 determine the specificity for chains of the SUMO
    Kirstin Keusekotten
    Institute for Genetics, University of Cologne, 50674 Koln, Germany
    Biochem J 457:207-14. 2014
  7. ncbi request reprint Functionality of alternative splice forms of the first enzymes involved in human molybdenum cofactor biosynthesis
    Petra Hänzelmann
    Institute of Plant Biology, Technical University of Braunschweig, D 38023 Braunschweig, Germany
    J Biol Chem 277:18303-12. 2002

Collaborators

  • Ralf R Mendel
  • R Jürgen Dohmen
  • Petra Hänzelmann
  • Kirstin Keusekotten
  • Nastassia Havarushka
  • Katrin Fischer-Schrader
  • M Frohlich
  • B Dejanovic
  • Tobias Lamkemeyer
  • Veronika N Bade
  • Christiane Horst
  • Anke Krause
  • Katrin Meyer-Teschendorf
  • Gerrit J K Praefcke
  • Kay Hofmann
  • S Nussberger
  • H Kashkar
  • Annie Miriam Sriramachandran

Detail Information

Publications7

  1. doi request reprint Structural basis of thermal stability of the tungsten cofactor synthesis protein MoaB from Pyrococcus furiosus
    Nastassia Havarushka
    Institute of Biochemistry, Department of Chemistry, University of Cologne, Cologne, Germany
    PLoS ONE 9:e86030. 2014
    ..The latter suggests a gain in conformational flexibility caused by the disruption of the hexamerization interface...
  2. doi request reprint S-palmitoylation represents a novel mechanism regulating the mitochondrial targeting of BAX and initiation of apoptosis
    M Frohlich
    Institute of Biochemistry, Department of Chemistry and Center for Molecular Medicine, Cologne University, Zulpicher Strasse 47, Cologne 50674, Germany
    Cell Death Dis 5:e1057. 2014
    ..Our findings suggest that S-palmitoylation of BAX at Cys126 is a key regulatory process of BAX-mediated apoptosis. ..
  3. ncbi request reprint Molybdenum in human health and disease
    Guenter Schwarz
    Institute of Biochemistry, Department of Chemistry, Center for Molecular Medicine, University of Cologne, Zulpicher Strasse 47, D 50674, Koln, Germany
    Met Ions Life Sci 13:415-50. 2013
    ..The underlying molecular basis of Moco deficiency, possible treatment options and links to other diseases, such as neuropsychiatric disorders, will be discussed. ..
  4. ncbi request reprint Molybdenum cofactor biosynthesis and molybdenum enzymes
    Gunter Schwarz
    Institute of Plant Biology, Technical University Braunschweig, 38023 Braunschweig, Germany
    Annu Rev Plant Biol 57:623-47. 2006
    ..3) Aldehyde oxidase catalyzes the last step of abscisic acid biosynthesis, and (4) xanthine dehydrogenase is essential for purine degradation and stress response...
  5. doi request reprint Molybdenum cofactors, enzymes and pathways
    Gunter Schwarz
    Institute of Biochemistry, Department of Chemistry and Centre for Molecular Medicine, University of Cologne, 47 Zuelpicher Street, 50674 Cologne, Germany
    Nature 460:839-47. 2009
    ....
  6. doi request reprint Multivalent interactions of the SUMO-interaction motifs in RING finger protein 4 determine the specificity for chains of the SUMO
    Kirstin Keusekotten
    Institute for Genetics, University of Cologne, 50674 Koln, Germany
    Biochem J 457:207-14. 2014
    ..In the present paper, we describe that the sequence and spacing of the SIMs (SUMO-interaction motifs) in RNF4 regulate the avidity-driven recognition of substrate proteins carrying SUMO chains of variable length...
  7. ncbi request reprint Functionality of alternative splice forms of the first enzymes involved in human molybdenum cofactor biosynthesis
    Petra Hänzelmann
    Institute of Plant Biology, Technical University of Braunschweig, D 38023 Braunschweig, Germany
    J Biol Chem 277:18303-12. 2002
    ..Comparative mutational studies of MOCS1A and the small subunit of the E. coli MPT synthase (MoaD) indicate a different function of the double glycine motifs in both proteins...