S Schwab

Summary

Affiliation: University of Regensburg
Country: Germany

Publications

  1. ncbi request reprint Long-term outcome after thrombolysis in telemedical stroke care
    S Schwab
    Department of Neurology, University of Regensburg, Regensburg, Germany
    Neurology 69:898-903. 2007
  2. ncbi request reprint Early hemicraniectomy in patients with complete middle cerebral artery infarction
    S Schwab
    Department of Neurology, University of Heidelberg, Germany
    Stroke 29:1888-93. 1998
  3. ncbi request reprint Moderate hypothermia in the treatment of patients with severe middle cerebral artery infarction
    S Schwab
    Department of Neurology, University of Heidelberg, Heidelberg, Germany
    Stroke 29:2461-6. 1998
  4. ncbi request reprint Neurometabolic changes during treatment with moderate hypothermia in a patient suffering from severe middle cerebral artery infarction
    W R Schäbitz
    Department of Neurology, University of Heidelberg Medical School, Heidelberg, Germany
    Cerebrovasc Dis 12:298-302. 2001
  5. doi request reprint Characteristics and outcome of patients with early complete neurological recovery after thrombolysis for acute ischemic stroke
    C Blinzler
    Department of Neurology, University of Erlangen Nuremberg, Erlangen, Germany
    Cerebrovasc Dis 31:185-90. 2011
  6. doi request reprint Safety and outcome after thrombolysis in stroke patients with mild symptoms
    M Kohrmann
    Department of Neurology, University of Erlangen, Schwabachanlage 6, Erlangen, Germany
    Cerebrovasc Dis 27:160-6. 2009
  7. doi request reprint Single versus bilateral external ventricular drainage for intraventricular fibrinolysis in severe ventricular haemorrhage
    D Staykov
    Department of Neurology, University of Erlangen Nuremberg, Erlangen, Germany
    J Neurol Neurosurg Psychiatry 81:105-8. 2010
  8. ncbi request reprint Feasibility and safety of moderate hypothermia after massive hemispheric infarction
    S Schwab
    Department of Neurology, University of Heidelberg, Germany
    Stroke 32:2033-5. 2001
  9. ncbi request reprint Off-label thrombolysis for acute ischemic stroke: rate, clinical outcome and safety are influenced by the definition of 'minor stroke'
    L Breuer
    Department of Neurology, University of Erlangen Nuremberg, Schwabachanlage 6, Erlangen, Germany
    Cerebrovasc Dis 32:177-85. 2011
  10. doi request reprint Sex differences in perihemorrhagic edema evolution after spontaneous intracerebral hemorrhage
    I Wagner
    Department of Neurology, University of Erlangen Nuremberg, Erlangen, Germany
    Eur J Neurol 19:1477-81. 2012

Detail Information

Publications43

  1. ncbi request reprint Long-term outcome after thrombolysis in telemedical stroke care
    S Schwab
    Department of Neurology, University of Regensburg, Regensburg, Germany
    Neurology 69:898-903. 2007
    ..Following recently published preliminary results on acute phase safety of telethrombolysis, the present study reports on its long-term functional outcome...
  2. ncbi request reprint Early hemicraniectomy in patients with complete middle cerebral artery infarction
    S Schwab
    Department of Neurology, University of Heidelberg, Germany
    Stroke 29:1888-93. 1998
    ..Several reports indicate a beneficial effect of hemicraniectomy in this situation. However, whether and when decompressive surgery is indicated in these patients is still a matter of debate...
  3. ncbi request reprint Moderate hypothermia in the treatment of patients with severe middle cerebral artery infarction
    S Schwab
    Department of Neurology, University of Heidelberg, Heidelberg, Germany
    Stroke 29:2461-6. 1998
    ..Clinical studies on moderate hypothermia in the treatment of acute ischemic stroke patients are still lacking...
  4. ncbi request reprint Neurometabolic changes during treatment with moderate hypothermia in a patient suffering from severe middle cerebral artery infarction
    W R Schäbitz
    Department of Neurology, University of Heidelberg Medical School, Heidelberg, Germany
    Cerebrovasc Dis 12:298-302. 2001
    ..Microdialysis monitoring of therapeutic hypothermia in severe hemispheric infarction might be a useful additional monitoring tool to assess the status of the brain and to predict further deterioration...
  5. doi request reprint Characteristics and outcome of patients with early complete neurological recovery after thrombolysis for acute ischemic stroke
    C Blinzler
    Department of Neurology, University of Erlangen Nuremberg, Erlangen, Germany
    Cerebrovasc Dis 31:185-90. 2011
    ..This study analyzes demographic and clinical characteristics of patients with early complete neurological recovery after thrombolysis...
  6. doi request reprint Safety and outcome after thrombolysis in stroke patients with mild symptoms
    M Kohrmann
    Department of Neurology, University of Erlangen, Schwabachanlage 6, Erlangen, Germany
    Cerebrovasc Dis 27:160-6. 2009
    ..We aimed to assess the safety and outcome of thrombolysis therapy in patients with minor but disabling stroke symptoms...
  7. doi request reprint Single versus bilateral external ventricular drainage for intraventricular fibrinolysis in severe ventricular haemorrhage
    D Staykov
    Department of Neurology, University of Erlangen Nuremberg, Erlangen, Germany
    J Neurol Neurosurg Psychiatry 81:105-8. 2010
    ..Intraventricular fibrinolysis (IVF) through bilateral external ventricular drains (EVD) may provide better access of the thrombolytic agent to the intraventricular clot, potentially influencing clot clearance and outcome...
  8. ncbi request reprint Feasibility and safety of moderate hypothermia after massive hemispheric infarction
    S Schwab
    Department of Neurology, University of Heidelberg, Germany
    Stroke 32:2033-5. 2001
    ..This multicenter study was performed to evaluate (1) the safety and feasibility of moderate hypothermia and (2) its potential to reduce intracranial hypertension in acute stroke patients...
  9. ncbi request reprint Off-label thrombolysis for acute ischemic stroke: rate, clinical outcome and safety are influenced by the definition of 'minor stroke'
    L Breuer
    Department of Neurology, University of Erlangen Nuremberg, Schwabachanlage 6, Erlangen, Germany
    Cerebrovasc Dis 32:177-85. 2011
    ..In addition, clinical outcome and safety data were compared to those from patients treated on-label, and the influence of different definitions of 'minor stroke' were examined...
  10. doi request reprint Sex differences in perihemorrhagic edema evolution after spontaneous intracerebral hemorrhage
    I Wagner
    Department of Neurology, University of Erlangen Nuremberg, Erlangen, Germany
    Eur J Neurol 19:1477-81. 2012
    ..Clinical data on sex differences in perihemorrhagic edema (PHE) after intracerebral hemorrhage (ICH) are lacking...
  11. ncbi request reprint Effects of hypertonic saline hydroxyethyl starch solution and mannitol in patients with increased intracranial pressure after stroke
    S Schwarz
    Department of Neurology, University of Heidelberg, Germany
    Stroke 29:1550-5. 1998
    ..The purpose of this study was to prospectively evaluate a protocol with hypertonic saline hydroxyethyl starch (HS-HES) and mannitol in stroke patients with increased intracranial pressure (ICP)...
  12. doi request reprint Waiting for platelet counts causes unsubstantiated delay of thrombolysis therapy
    L Breuer
    Department of Neurology, University of Erlangen Nuremberg, Erlangen Nuremberg, Germany
    Eur Neurol 69:317-20. 2013
    ..We aimed to assess the incidence of thrombocytopenia in IVT patients, outcome after thrombolysis in affected patients and the time gained by initiating treatment prior to availability of PC results...
  13. doi request reprint Radiopacity of intracerebral hemorrhage correlates with perihemorrhagic edema
    I Wagner
    Department of Neurology, University of Erlangen Nuremberg, Erlangen, Germany
    Eur J Neurol 19:525-8. 2012
    ..We investigated the relationship between ICH radiopacity on CT as a marker of hematoma iron content and perihemorrhagic edema (PHE) after ICH...
  14. ncbi request reprint Suboptimum hemicraniectomy as a cause of additional cerebral lesions in patients with malignant infarction of the middle cerebral artery
    S Wagner
    Department of Neurology, University of Heidelberg, Germany
    J Neurosurg 94:693-6. 2001
    ..The goal of this study was to determine the frequency of hemicraniectomy-associated lesions and their potential effect on the risk of mortality in patients suffering from malignant infarction of the middle cerebral artery MCA)...
  15. ncbi request reprint Intravenous brain-derived neurotrophic factor reduces infarct size and counterregulates Bax and Bcl-2 expression after temporary focal cerebral ischemia
    W R Schäbitz
    Department of Neurology, University of Heidelberg, Germany
    Stroke 31:2212-7. 2000
    ..In this experiment we studied the effect of intravenous BDNF delivered after focal cerebral ischemia on neurological outcome, infarct size, and expression of proapoptotic and antiapoptotic proteins Bax and Bcl-2, respectively...
  16. ncbi request reprint Effect and feasibility of controlled rewarming after moderate hypothermia in stroke patients with malignant infarction of the middle cerebral artery
    T Steiner
    Department of Neurology, University of Heidelberg, Heidelberg, Germany
    Stroke 32:2833-5. 2001
    ..However, during passive rewarming, ICP continuously rises and some patients suffer transtentorial herniation...
  17. ncbi request reprint Therapeutic hypothermia for space-occupying Herpes simplex virus encephalitis
    I Wagner
    Department of Neurology, University Hospital of Erlangen, University of Erlangen Nuremberg, Erlangen, Germany
    Minerva Anestesiol 77:371-4. 2011
    ..Induced moderate hypothermia of 33 °C resulted in fast and sustained control of intracranial pressure. After three months, the patient had a fairly good functional outcome with a Glasgow Outcome Scale score of 4...
  18. ncbi request reprint Incidence and prognostic significance of fever following intracerebral hemorrhage
    S Schwarz
    Department of Neurology, University of Heidelberg, Germany
    Neurology 54:354-61. 2000
    ..To investigate the incidence and prognostic significance of fever on presentation and during the subsequent 72 hours in patients with spontaneous supratentorial intracerebral hemorrhage (ICH)...
  19. ncbi request reprint Delayed neuroprotective effect of insulin-like growth factor-i after experimental transient focal cerebral ischemia monitored with mri
    W R Schäbitz
    Department of Neurology, University of Heidelberg, Heidelberg, Germany
    Stroke 32:1226-33. 2001
    ..Therefore, in the present study, we evaluated, by applying MRI monitoring, whether a clinically relevant systemic administration of IGF-I can achieve a long-lasting neuroprotective effect...
  20. doi request reprint Sonographic monitoring of ventricle enlargement in posthemorrhagic hydrocephalus
    I C Kiphuth
    Department of Neurology, University of Erlangen, Schwabachanlage 6, 91054 Erlangen, Germany
    Neurology 76:858-62. 2011
    ..We performed a prospective observational study on the use of transcranial duplex sonography to monitor changes in width of the lateral ventricles during clamping as an alternative to CT...
  21. ncbi request reprint Stroke magnetic resonance imaging within 6 hours after onset of hyperacute cerebral ischemia
    P D Schellinger
    Department of Neurology, University of Heidelberg Medical School, Germany
    Ann Neurol 49:460-9. 2001
    ..Patients with proximal vessel occlusions have a larger amount of tissue at risk, a lower recanalization rate, and a worse outcome. Urgent recanalization seems to be of utmost importance for these patients...
  22. ncbi request reprint Changes in cerebral blood flow and oxygen metabolism during moderate hypothermia in patients with severe middle cerebral artery infarction
    E Keller
    Department of Neurology, Neurocritical Care Unit, University of Heidelberg, Heidelberg, Germany
    Neurosurg Focus 8:e4. 2000
    ..The effect of hypothermia on cerebral hemodynamics is a matter of controversial discussion in literature. Clinical studies have yet to be performed in patients with ischemic stroke after induction of hypothermia...
  23. ncbi request reprint Influence of positive end-expiratory pressure on intracranial pressure and cerebral perfusion pressure in patients with acute stroke
    D Georgiadis
    Department of Neurology, University of Heidelberg, Germany
    Stroke 32:2088-92. 2001
    ..We undertook this study to evaluate the influence of positive end-expiratory pressure (PEEP) on intracranial pressure (ICP) and cerebral perfusion pressure (CPP) in patients with acute stroke...
  24. ncbi request reprint Poliomyelitic-like illness in central European encephalitis
    P D Schellinger
    Department of Neurology, University of Heidelberg, Germany
    Neurology 55:299-302. 2000
    ..Autopsy in one patient showed severe cervicothoracic inflammation with changes almost exclusively in anterior horn cells and roots, as typically seen in poliomyelitis...
  25. ncbi request reprint Magnetic evoked potentials in neurocritical care patients with acute brainstem lesions
    S Schwarz
    Department of Neurology, University of Heidelberg, INF 400, Heidelberg, Germany
    J Neurol Sci 172:30-7. 2000
    ..We evaluated the clinical and predictive value of MEPs by magnetic transcranial stimulation in intensive care patients with acute brainstem lesions of predominantly vascular origin...
  26. doi request reprint Advances in the management of intracerebral hemorrhage
    J B Kuramatsu
    Department of Neurology, University of Erlangen Nuremberg, Schwabachanlage 6, 91054 Erlangen, Germany
    J Neural Transm 120:S35-41. 2013
    ..This review will summarize advanced treatment strategies and novel approaches which are currently under investigation...
  27. doi request reprint Neurochemical monitoring of therapeutic effects in large human MCA infarction
    C Berger
    Department of Neurology, University of Heidelberg, Im Neuenheimer Feld 400, 69120, Heidelberg, Germany
    Neurocrit Care 9:352-6. 2008
    ..In order to assess the potential effects of hemicraniectomy, hypothermia and conservative therapy on these substances, we used neurochemical monitoring with microdialysis in large human stroke patients...
  28. doi request reprint Influence of intraventricular fibrinolytic therapy with rt-PA on the long-term outcome of treated patients with spontaneous basal ganglia hemorrhage: a case-control study
    H B Huttner
    Department of Neurology, University of Erlangen, Erlangen, Germany
    Eur J Neurol 15:342-9. 2008
    ..The results of the prospective randomized trial (Clot Lysis: Evaluating Accelerated Resolution of Intraventricular Hemorrhage) need to be awaited...
  29. ncbi request reprint Endovascular cooling for moderate hypothermia in patients with acute stroke: first results of a novel approach
    D Georgiadis
    Department of Neurology, University of Heidelberg, Germany
    Stroke 32:2550-3. 2001
    ..CONCLUSIONS: Induction and maintenance of hypothermia with an intravenous cooling device are feasible. The safety of this approach remains to be evaluated...
  30. doi request reprint Physical activity in multiple sclerosis: a comparative study of vitamin D, brain-derived neurotrophic factor and regulatory T cell populations
    A Waschbisch
    Department of Neurology, University Hospital Erlangen, Erlangen, Germany
    Eur Neurol 68:122-8. 2012
    ..Objective: To assess potential relationships between cardiorespiratory fitness, cognitive function, and immune parameters in physically active and inactive MS patients...
  31. ncbi request reprint Ischaemic stroke: acute management, intensive care, and future perspectives
    R Kollmar
    Department of Neurology, University of Erlangen, Schwabachanlage 6, 91054 Erlangen, Germany
    Br J Anaesth 99:95-101. 2007
    ..Recent research, that highlights the importance of acute management of stroke in terms of thrombolysis, thrombolytic agents, decompressive surgery, and hypothermia, has been reviewed...
  32. doi request reprint Smell and taste disorders in polyneuropathy: a prospective study of chemosensory disorders
    J G Heckmann
    Department of Neurology, University of Erlangen Nuremberg, Erlangen, Germany
    Acta Neurol Scand 120:258-63. 2009
    ..The aim of the study was to assess the occurrence and the frequency of chemosensory dysfunction in patients with polyneuropathy (PNP)...
  33. ncbi request reprint Masking of vertebral artery dissection by severe trauma to the cervical spine
    P D Schellinger
    Department of Neurology, University of Heidelberg, Germany
    Spine (Phila Pa 1976) 26:314-9. 2001
    ..A prospective case study was performed...
  34. pmc Acute disseminated encephalomyelitis after parenteral therapy with herbal extracts: a report of two cases
    S Schwarz
    Department of Neurology, University of Heidelberg, 400 Im Neuenheimer Feld, Heidelberg 69120, Germany
    J Neurol Neurosurg Psychiatry 69:516-8. 2000
    ..Both patients recovered rapidly after treatment with methylprednisolone. Acute disseminated encephalomyelitis should be considered a rare complication of parenteral therapy with herbal extracts...
  35. ncbi request reprint Hemicraniectomy and moderate hypothermia in patients with severe ischemic stroke
    D Georgiadis
    Department of Neurology, University of Heidelberg, Heidelberg, Germany
    Stroke 33:1584-8. 2002
    ....
  36. ncbi request reprint Noninvasive monitoring of hypertensive breakthrough of cerebral autoregulation in a patient with acute ischemic stroke
    D Georgiadis
    Department of Neurology, University of Heidelberg, Germany
    Cerebrovasc Dis 14:129-32. 2002
    ..We describe the first documentation of hypertensive breakthrough of cerebral autoregulation in a patient with acute stroke with transcranial Doppler sonography...
  37. ncbi request reprint Cerebral autoregulation under moderate hypothermia in patients with acute stroke
    D Georgiadis
    Department of Neurology, University of Heidelberg, Heidelberg, Germany
    Stroke 33:3026-9. 2002
    ..We undertook this study to examine the integrity of cerebral autoregulation in patients with acute ischemic stroke treated with moderate hypothermia (33 degrees C)...
  38. ncbi request reprint Therapy of severe ischemic stroke: breaking the conventional thinking
    S Schwab
    Department of Neurology, University of Heidelberg, Heidelberg, Germany
    Cerebrovasc Dis 20:169-78. 2005
    ..Experience in stroke patients suggest that hypothermia may offer a new approach for the treatment of acute cerebral ischemia...
  39. ncbi request reprint Does acute occlusion of the carotid T invariably have a poor outcome?
    D Georgiadis
    Department of Neurology, University of Heidelberg, Germany
    Neurology 63:22-6. 2004
    ..To evaluate the prognosis of patients with acute occlusion of the carotid T...
  40. ncbi request reprint [Spontaneous intracerebral hemorrhages]
    A Hug
    Abteilung Neurologie, Neurologische Klinik, Universitatsklinikum Heidelberg, Heidelberg
    Nervenarzt 75:953-61. 2004
    ..Large randomized controlled trials provide only little evidence for therapeutic strategies in patients with spontaneous ICH. In this review we summarize the available data and give recommendations on the management of spontaneous ICH...
  41. ncbi request reprint IV thrombolysis in patients with acute stroke due to spontaneous carotid dissection
    D Georgiadis
    Department of Neurology, University of Zurich, Zurich, Switzerland
    Neurology 64:1612-4. 2005
    ..At 3 months, median NIHSS was 7 and median modified Rankin Scale (mRS) 2.5; mRS < or = 2 was observed in 17 patients...
  42. doi request reprint [The Erlangen examination. An alternative to multiple choice testing for German neurology students]
    J G Heckmann
    Neurologische Klinik, Universitatsklinikum, Schwabachanlage 6, Erlangen, Germany
    Nervenarzt 79:676-83. 2008
    ..The Erlangen Neurological Exam Structured (ERNEST) is an alternative for assessing competency in clinical knowledge at the end of the neurological general education. The answers must be given in written, short essay format...
  43. ncbi request reprint [The new 2005 resuscitation guidelines of the European Resuscitation Council: comments and supplements]
    V Wenzel
    Univ Klinik für Anaesthesie und Allgemeine Intensivmedizin, Medizinische Universitat, Anichstrasse 35, 6020, Innsbruck, Austria
    Anaesthesist 55:958-66, 968-72, 974-9. 2006
    ..Despite bad prognosis, CPR in trauma patients may be successful in select cases. Any CPR training is better than nothing; simplification of contents and processes remains important...