V Schuster

Summary

Affiliation: University of Leipzig
Country: Germany

Publications

  1. ncbi request reprint Plasminogen deficiency
    V Schuster
    Hospital for Children and Adolescents, Medical Faculty of Leipzig University, Liebigstrasse 20a, Leipzig, Germany
    J Thromb Haemost 5:2315-22. 2007
  2. doi request reprint Immunogenicity and safety assessments after one and two doses of a refrigerator-stable tetravalent measles-mumps-rubella-varicella vaccine in healthy children during the second year of life
    Volker Schuster
    Hospital for Children and Adolescents, University of Leipzig, Leipzig, Germany
    Pediatr Infect Dis J 27:724-30. 2008
  3. pmc Lasting immune memory against hepatitis B in children after primary immunization with 4 doses of DTPa-HBV-IPV/Hib in the first and 2nd year of life
    Michael Steiner
    University Hospital for Children and Adolescents, Leipzig, Germany
    BMC Infect Dis 10:9. 2010
  4. doi request reprint Identification of three novel plasminogen (PLG) gene mutations in a series of 23 patients with low PLG activity
    Jürgen Klammt
    Hospital for Children and Adolescents, University of Leipzig, Leipzig, Germany
    Thromb Haemost 105:454-60. 2011
  5. ncbi request reprint Homozygous and compound-heterozygous type I plasminogen deficiency is a common cause of ligneous conjunctivitis
    V Schuster
    Children s Hospital, University of Leipzig, Germany
    Thromb Haemost 85:1004-10. 2001
  6. ncbi request reprint [Gianotti-Crosti syndrome in an infant following immunization]
    N Schwerk
    Universitätsklinik und Poliklinik für Kinder und Jugendliche Leipzig
    Klin Padiatr 217:297-9. 2005
  7. ncbi request reprint Decreased factor XIII activity during severe Henoch-Schoenlein purpura -- does it play a role?
    F Prenzel
    Clinic for Pediatric and Adolescent Medicine, University Hospitals of Leipzig
    Klin Padiatr 218:174-6. 2006
  8. ncbi request reprint X-linked lymphoproliferative disease is caused by deficiency of a novel SH2 domain-containing signal transduction adaptor protein
    V Schuster
    Department of Pediatrics, Leipzig University School of Medicine, Germany
    Immunol Rev 178:21-8. 2000
  9. doi request reprint A hospital based study on inter- and intragenotypic diversity of human rotavirus A VP4 and VP7 gene segments, Germany
    C Pietsch
    Institute of Virology, Leipzig University, Johannisallee 30, 04103 Leipzig, Germany
    J Clin Virol 50:136-41. 2011
  10. ncbi request reprint Lethal influenza B myocarditis in a child and review of the literature for pediatric age groups
    H Frank
    Hospital for Children and Adolescents, University of Leipzig, Liebigstrasse 20a, 04103, Leipzig, Germany
    Infection 38:231-5. 2010

Collaborators

Detail Information

Publications35

  1. ncbi request reprint Plasminogen deficiency
    V Schuster
    Hospital for Children and Adolescents, Medical Faculty of Leipzig University, Liebigstrasse 20a, Leipzig, Germany
    J Thromb Haemost 5:2315-22. 2007
    ....
  2. doi request reprint Immunogenicity and safety assessments after one and two doses of a refrigerator-stable tetravalent measles-mumps-rubella-varicella vaccine in healthy children during the second year of life
    Volker Schuster
    Hospital for Children and Adolescents, University of Leipzig, Leipzig, Germany
    Pediatr Infect Dis J 27:724-30. 2008
    ..This study (104389/NCT00127023) was undertaken to assess the immunogenicity and safety of a new refrigerator-stable tetravalent MMRV vaccine after 1 dose and after 2 doses administered during the second year of life...
  3. pmc Lasting immune memory against hepatitis B in children after primary immunization with 4 doses of DTPa-HBV-IPV/Hib in the first and 2nd year of life
    Michael Steiner
    University Hospital for Children and Adolescents, Leipzig, Germany
    BMC Infect Dis 10:9. 2010
    ..We assessed antibody persistence and immune memory in children 4-5 years of age, previously vaccinated with four doses of combined hexavalent DTPa-HBV-IPV/Hib vaccine (Infanrix hexa)...
  4. doi request reprint Identification of three novel plasminogen (PLG) gene mutations in a series of 23 patients with low PLG activity
    Jürgen Klammt
    Hospital for Children and Adolescents, University of Leipzig, Leipzig, Germany
    Thromb Haemost 105:454-60. 2011
    ..Transmission of genetic and clinical data to the recently established Plasminogen Deficiency Registry should help to determine the prevalence of the disease and to develop more efficient treatment strategies...
  5. ncbi request reprint Homozygous and compound-heterozygous type I plasminogen deficiency is a common cause of ligneous conjunctivitis
    V Schuster
    Children s Hospital, University of Leipzig, Germany
    Thromb Haemost 85:1004-10. 2001
    ..Our results suggest that the Lys19-->Glu mutation is the most prevalent mutation in the plasminogen gene of patients with ligneous conjunctivitis...
  6. ncbi request reprint [Gianotti-Crosti syndrome in an infant following immunization]
    N Schwerk
    Universitätsklinik und Poliklinik für Kinder und Jugendliche Leipzig
    Klin Padiatr 217:297-9. 2005
    ..Our data and review of the literature suggest that GCS is rarely associated with immunizations, especially when performed with inactivated vaccines...
  7. ncbi request reprint Decreased factor XIII activity during severe Henoch-Schoenlein purpura -- does it play a role?
    F Prenzel
    Clinic for Pediatric and Adolescent Medicine, University Hospitals of Leipzig
    Klin Padiatr 218:174-6. 2006
    ..In patients with Henoch-Schoenlein purpura (HSP), particularly with severe gastrointestinal symptoms, an associated decrease of plasma factor XIII has been observed...
  8. ncbi request reprint X-linked lymphoproliferative disease is caused by deficiency of a novel SH2 domain-containing signal transduction adaptor protein
    V Schuster
    Department of Pediatrics, Leipzig University School of Medicine, Germany
    Immunol Rev 178:21-8. 2000
    ..Further functional studies of the SH2D1A protein will probably provide new insights into the pathogenesis of severe infectious mononucleosis, malignant lymphomas and immunodeficiency in patients with XLP...
  9. doi request reprint A hospital based study on inter- and intragenotypic diversity of human rotavirus A VP4 and VP7 gene segments, Germany
    C Pietsch
    Institute of Virology, Leipzig University, Johannisallee 30, 04103 Leipzig, Germany
    J Clin Virol 50:136-41. 2011
    ..A major challenge in immunisation is the vast inter- and intragenotypic diversity accomplished by circulating rotaviruses...
  10. ncbi request reprint Lethal influenza B myocarditis in a child and review of the literature for pediatric age groups
    H Frank
    Hospital for Children and Adolescents, University of Leipzig, Liebigstrasse 20a, 04103, Leipzig, Germany
    Infection 38:231-5. 2010
    ..Cardiac arrest occurred suddenly, resuscitation efforts were not successful, and the patient died of congestive heart failure 24 h after admission to the hospital...
  11. ncbi request reprint [Varicella vaccination: who should be vaccinated these days?]
    Boris Hugle
    Universitätsklinik für Kinder und Jugendliche, Leipzig
    MMW Fortschr Med 147:31-2, 34-5. 2005
    ..Experience gained in the United States show that widespread introduction of VZV vaccination results in a decrease in both the incidence of varicella and concomitant complications including herpes zoster...
  12. ncbi request reprint Simultaneous manifestation of fulminant infectious mononucleosis with haemophagocytic syndrome and B-cell lymphoma in X-linked lymphoproliferative disease
    Boris Hugle
    Department of Pediatrics, University of Leipzig, Oststrasse 21 25, Leipzig, Germany
    Eur J Pediatr 166:589-93. 2007
    ..Fatal EBV infection in male infants is highly indicative of XLP. Virus-associated haemophagocytic syndrome and B-cell lymphoma can occur concomitantly and may be difficult to distinguish due to their similar histological pictures...
  13. ncbi request reprint Molecular and clinical spectrum of type I plasminogen deficiency: A series of 50 patients
    Katrin Tefs
    Hospital for Children and Adolescents, University of Leipzig, Oststrasse 21 25, D 04317 Leipzig, Germany
    Blood 108:3021-6. 2006
    ..These results demonstrate impaired secretion of mutant PLG proteins as a common molecular pathomechanism in type I PLG deficiency...
  14. ncbi request reprint A missense mutation in the ZFHX1B gene associated with an atypical Mowat-Wilson syndrome phenotype
    Wolfram Heinritz
    Institute of Human Genetics, University of Leipzig Medical Faculty, Leipzig, Germany
    Am J Med Genet A 140:1223-7. 2006
    ..We report on the clinical findings in a 2(1/2)-year-old boy with some aspects out of the MWS-spectrum in addition to unusual anomalies and a novel missense mutation in the ZFHX1B gene...
  15. ncbi request reprint Addison's disease and severe encephalopathy in an infant with HIV infection
    Skadi Beblo
    Universitätsklinik und Poliklinik für Kinder und Jugendliche, Universitat Leipzig, Leipzig, Germany
    J Pediatr Endocrinol Metab 23:297-302. 2010
    ..To discuss the overlapping clinical spectrum of encephalopathy due to Addison's disease and HIV infection...
  16. doi request reprint Pyogenic osteomyelitis of the vertebral arch in children
    Martin Reiss-Zimmermann
    University Hospital Leipzig, Department of Pediatric Radiology, Liebigstr 20a, 04103 Leipzig, Germany
    J Pediatr Surg 45:1737-40. 2010
    ..Antibiotic therapy with or without surgical intervention provided successful management. With the recurrence observed in 1 child, the most optimal treatment of this condition might still be unknown...
  17. ncbi request reprint Unusual presentation of congenital disorder of glycosylation type 1a: congenital persistent thrombocytopenia, hypertrophic cardiomyopathy and hydrops-like aspect due to marked peripheral oedema
    Vera Noelle
    University Children s Hospital, Oststrasse 21 25, 04317 Leipzig, Germany
    Eur J Pediatr 164:223-6. 2005
    ..Persistent congenital thrombocytopenia and hyperferritinaemia in the absence of infection were noted. Bone marrow cytology revealed a macrophage activation of unknown aetiology...
  18. ncbi request reprint Persistent hypogammaglobulinemia following mononucleosis in boys is highly suggestive of X-linked lymphoproliferative disease--report of three cases
    B Hugle
    Hospital for Children and Adolescents, University of Leipzig, 04317 Leipzig, Germany
    J Clin Immunol 24:515-22. 2004
    ..Development of persistent hypogammaglobulinemia after severe primary EBV infection seems to be a specific diagnostic sign for XLP even in males with unremarkable family history...
  19. ncbi request reprint A K19E missense mutation in the plasminogen gene is a common cause of familial hypoplasminogenaemia
    Katrin Tefs
    Children s Hospital, University of Leipzig, Germany
    Blood Coagul Fibrinolysis 14:411-6. 2003
    ..In conclusion, the K19E mutation in the plasminogen gene is a common cause of hypoplasminogenaemia in Scotland, with an estimated prevalence of around 0.14%...
  20. ncbi request reprint Characterization of plasminogen variants in healthy subjects and plasminogen mutants in patients with inherited plasminogen deficiency by isoelectric focusing gel electrophoresis
    Katrin Tefs
    Children s Hospital, University of Leipzig, Germany
    Thromb Haemost 92:352-7. 2004
    ..In conclusion, plg phenotyping by IEF in combination with molecular analysis of the plg gene seems to be a useful method for characterization of plg variants and mutants...
  21. ncbi request reprint Limited sequence heterogeneity of Epstein-Barr virus nuclear antigen 1 in benign and malignant EBV-associated disorders
    V Schuster
    Children s Hospital, University of Leipzig, Germany
    Infection 28:137-42. 2000
    ..EBNA-1 is suggested to be oncogenic in vivo since its expression induces B-cell neoplasia in transgenic mice...
  22. ncbi request reprint A season of aseptic meningitis in Germany: epidemiologic, clinical and diagnostic aspects
    Antje Böttner
    Children s Hospital, University of Leipzig, Germany
    Pediatr Infect Dis J 21:1126-32. 2002
    ....
  23. ncbi request reprint Ligneous conjunctivitis
    Volker Schuster
    Department of Pediatrics, Leipzig University Medical School, Leipzig, Germany
    Surv Ophthalmol 48:369-88. 2003
    ....
  24. ncbi request reprint Difficulties in mutation screening of the plasminogen (PLG) gene in patients with ligneous conjunctivitis and severe hypoplasminogenemia
    Katrin Tefs
    Arch Ophthalmol 125:1303; author reply 1303. 2007
  25. ncbi request reprint Ligneous conjunctivitis, hydrocephalus, hydrocele, and pulmonary involvement in a child with homozygous type I plasminogen deficiency
    Ergin Ciftci
    Department of Paediatric Infectious Diseases, University of Ankara Medical School, 06100 Dikimevi Ankara, Turkey
    Eur J Pediatr 162:462-5. 2003
    ..Both of his parents were heterozygous for this mutation. He died due to respiratory failure during follow-up...
  26. ncbi request reprint Hypoplasminogenemia with ligneous periodontitis: a failed local therapeutic approach
    Idil Kurtulus
    Department of Periodontology, Faculty of Dentistry, Istanbul University, Istanbul, Turkey
    J Periodontol 78:1164-75. 2007
    ..Pseudomembranes may develop on the gingivae, and there may be periodontal involvement...
  27. ncbi request reprint [MMW questions colleagues about prescriptions. How to manage children with otitis media? (interview by Thomas Meissner)]
    Karl Bernd Huttenbrink
    MMW Fortschr Med 145:12-3. 2003
  28. ncbi request reprint Therapeutic approaches in the treatment of ligneous conjunctivitis, the most common clinical manifestation of a systemic disease, caused by severe type I plasminogen deficiency
    Katrin Tefs
    Am J Ophthalmol 138:699; author reply 699-700. 2004
  29. ncbi request reprint Mutation spectrum of human SLC39A4 in a panel of patients with acrodermatitis enteropathica
    Sebastien Kury
    Laboratoire d Etude du Polymorphisme de l ADN, Faculte de Medecine, 1 rue Gaston Veil, 44035 Nantes Cedex, France
    Hum Mutat 22:337-8. 2003
    ..850G>A (p.Glu284Lys) and c.193-113T>C] were also observed at homozygous state in a French family formerly described. This study brings to 21 the number of reported SLC39A4 mutations in AE families...
  30. ncbi request reprint A nucleic acid exchange in Intron F (Intron F-14T>G) in the human plasminogen gene is only a common polymorphism and not a true mutation
    Katrin Tefs
    Thromb Haemost 91:830-1; author reply 832. 2004
  31. ncbi request reprint Immunogenicity and reactogenicity of a trivalent influenza split vaccine in previously unvaccinated children aged 6-9 and 10-13 years
    Ruprecht Schmidt-Ott
    GlaxoSmithKline, Theresienhöhe 11, 80339 Munich, Germany
    Vaccine 26:32-40. 2007
    ....
  32. ncbi request reprint Bladder exstrophy and Epstein type congenital macrothrombocytopenia: evidence for a common cause?
    Boris Utsch
    Department of Pediatrics, University of Erlangen Nuremberg, Erlangen, Germany
    Am J Med Genet A 140:2251-3. 2006
  33. ncbi request reprint Inherited plasminogen deficiency presenting as ligneous vaginitis: a case report with molecular correlation and review of the literature
    Tamara L Lotan
    Pathology, University of Chicago, Chicago, IL 60637, USA
    Hum Pathol 38:1569-75. 2007
    ..Recently, replacement therapy with plasminogen has been shown to significantly improve systemic symptoms, making ligneous mucositis a serious but treatable condition...
  34. ncbi request reprint Ligneous inflammation involving the female genital tract
    Abdullah Karaer
    Department of Obstetrics and Gynecology, Dr Zekai Tahir Burak Women s Health Education and Reserach Hospital, Ankara, Turkey
    J Obstet Gynaecol Res 33:581-4. 2007
    ..However, the histology of lesions is characteristic and a diagnosis can be made quite easily once it has been considered...
  35. ncbi request reprint Ligneous (pseudomembranous) inflammation involving the female genital tract associated with type-1 plasminogen deficiency
    Liron Pantanowitz
    Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA
    Int J Gynecol Pathol 23:292-5. 2004
    ..We present a patient with ligneous inflammation of her genital, middle ear, and oral mucosa that was associated with type-1 homozygous plasminogen deficiency due to a novel missense mutation in the plasminogen gene...