Research Topics
| Paulus G SchurrSummaryAffiliation: University of Hamburg Country: Germany Publications
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Detail Information
Publications
Central mesenteric lymph node BER-Ep4+ cells in colorectal cancer: challenge to sentinel node concept?Paulus G Schurr
Department of General, Visceral and Thoracic Surgery, University Medical Center Hamburg Eppendorf, Hamburg, Germany
Dig Surg 24:19-27. 2007..The role of sentinel lymph nodes in colorectal cancer remains unclear...
Aggressive surgery improves long-term survival in neuroendocrine pancreatic tumors: an institutional experiencePaulus G Schurr
Department of General, Visceral and Thoracic Surgery, University Medical Center of Hamburg Eppendorf, University of Hamburg, Hamburg, Germany
Ann Surg 245:273-81. 2007..To evaluate surgical strategies for neuroendocrine pancreatic tumors (NEPT) in the light of the new WHO classification from 2004 and to draw conclusions for future surgical concepts...
Radical redo surgery for local rectal cancer recurrence improves overall survival: a single center experiencePaulus Schurr
Department of General, Visceral and Thoracic Surgery, University Medical Center Hamburg Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany
J Gastrointest Surg 12:1232-8. 2008..To date, the survival benefit of redo surgery in locally recurrent rectal adenocarcinoma remains unclear...- Clinical value of loss of heterozygosity in serum microsatellite DNA of patients with gastrointestinal stromal tumorsPaulus G Schurr
Department of General, Visceral and Thoracic Surgery, University Medical Center Hamburg Eppendorf, Martinistrasse 52, Hamburg
J Clin Gastroenterol 43:27-35. 2009..To study the role of loss of heterozygosity (LOH) in serum microsatellite DNA of patients with gastrointestinal stromal tumors (GIST)... - Microsatellite DNA alterations of gastrointestinal stromal tumors are predictive for outcomePaulus Schurr
Department of General, Visceral, and Thoracic Surgery and Institute of Pathology, University Medical Center Hamburg Eppendorf, Hamburg, Germany
Clin Cancer Res 12:5151-7. 2006..In gastrointestinal stromal tumors (GIST), loss of heterozygosity (LOH) on chromosome 22 and its presumptive biological function has been described. The prognostic value of these and other DNA regions for patient survival remains unclear... - L1 is associated with micrometastatic spread and poor outcome in colorectal cancerJussuf T Kaifi
Department of General, Visceral and Thoracic Surgery, University Medical Center Hamburg Eppendorf, Hamburg, Germany
Mod Pathol 20:1183-90. 2007..It may have a role in early metastatic spread, as L1 is associated with micrometastases to both the lymph nodes and bone marrow. Thus, L1 should be explored further as a target for adjuvant therapy for micrometastatic disease... - Subset of esophageal adenocarcinoma expresses adhesion molecule l1 in contrast to squamous cell carcinomaTamina Rawnaq
Department of General, Visceral and Thoracic Surgery, University Medical Center Hamburg Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany
Anticancer Res 29:1195-9. 2009..The aim of the current study was to determine L1 expression in esophageal cancer and to evaluate whether L1 could serve as a potential marker and therapeutic target for this tumor type... - Short tandem repeat polymorphism in exon 4 of esophageal cancer-related gene 2 detected in genomic DNA is a prognostic marker for esophageal cancerJussuf T Kaifi
Department of General, Visceral and Thoracic Surgery, University Medical Center Hamburg Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany
Am J Surg 194:380-4. 2007..Short tandem repeat (STR) polymorphisms in exon 4 of the esophageal cancer-related gene 2 (ECRG2) are a risk marker for esophageal carcinoma. The aim of the present study was to correlate these STRs with clinical outcome... - Nodal microinvolvement in patients with carcinoma of the papilla of vater receiving no adjuvant chemotherapyDean Bogoevski
University Clinic Eppendorf, Hamburg, Germany
J Gastrointest Surg 12:1830-7; discussion 1837-8. 2008..To assess the prognostic significance of nodal microinvolvement in patients with carcinoma of the papilla of Vater... - Lymphatic spread and microinvolvement in adenocarcinoma of the esophago-gastric junctionPaulus G Schurr
Department of General, Visceral and Thoracic Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
J Surg Oncol 94:307-15. 2006..CONCLUSIONS: Lymphatic microinvolvement shows a high incidence in curatively resected EGJ cancer. Spread to mediastinal lymph nodes seems to necessitate lymphadenectomy of the thoracic cavity in either type... - Absence of L1 in pancreatic masses distinguishes adenocarcinomas from poorly differentiated neuroendocrine carcinomasJussuf T Kaifi
Department of General, Visceral and Thoracic Surgery, University Medical Center Hamburg Eppendorf, 20246 Hamburg, Germany
Anticancer Res 26:1167-70. 2006..The aim of this study was to determine the expression of L1 in pancreatic adenocarcinomas to evaluate whether L1 might differentiate between pancreatic carcinomas of neuroendocrine and ductal origin... - Short tandem repeat polymorphisms of exon 4 in Kazal-type gene ECRG2 in pancreatic carcinoma and chronic pancreatitisJussuf T Kaifi
Department of General, Visceral and Thoracic Surgery, University Medical Center Hamburg Eppendorf Martinistrasse 52, 20246 Hamburg, Germany
Anticancer Res 27:69-73. 2007..Kazal-type genes are associated with cancer and pancreatic disease. The aim of the present study was to examine whether ECRG2 STR polymorphisms are associated with pancreatic carcinoma and chronic pancreatitis... - Similar patterns of loss of heterozygosity in serum of adenocarcinoma of the distal oesophagus and the cardia in early diagnosisRobin Wachowiak
Department of General, Visceral and Thoracic Surgery, University Medical Center Hamburg Eppendorf, 20246 Hamburg, Germany
Anticancer Res 27:477-81. 2007..The aim of our study was to investigate LOH in the serum of patients with adenocarcinoma of the distal oesophagus and the cardia for diagnostic and prognostic utility... - En bloc vascular resection for locally advanced pancreatic malignancies infiltrating major blood vessels: perioperative outcome and long-term survival in 136 patientsEmre F Yekebas
Department of General, Visceral and Thoracic Surgery, University Medical Centre Hamburg Eppendorf, University of Hamburg, Hamburg, Germany
Ann Surg 247:300-9. 2008..To assess in-hospital complication rates and survival duration after en bloc vascular resection (VR) for infiltration of pancreatic malignancies in major vessels... - Short tandem repeat polymorphism in exon 4 of esophageal cancer related gene 2 predicts relapse of oral squamous cell carcinomaMarco Blessmann
Department of Oral Surgery, University Medical Center Hamburg Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany
Oral Oncol 44:143-7. 2008..05). STR polymorphism TCA3/TCA3 in exon 4 of ECRG2 is associated with poor relapse-free survival in surgically completely resected OSCC patients and might be a potential prognostic marker... - Thy-1 as a potential novel diagnostic marker for gastrointestinal stromal tumorsDespoina Oikonomou
Department of General, Visceral and Thoracic Surgery, University Medical Center Hamburg Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany
J Cancer Res Clin Oncol 133:951-5. 2007..Thy-1, a cell-surface glycoprotein, is a marker for several types of stem cells and particularly for neuronal precursor cells. The aim of this study was to determine Thy-1 expression in GISTs... - Midkine as a prognostic marker for gastrointestinal stromal tumorsJussuf T Kaifi
Department of General, Visceral and Thoracic Surgery, University Medical Center Hamburg Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany
J Cancer Res Clin Oncol 133:431-5. 2007..The outcome of patients with gastrointestinal stromal tumors (GISTs) is correlated with tumor size and mitotic count. The aim of this study was to determine MK expression in GISTs... - Allelic loss of Hox11L1 gene locus predicts outcome of gastrointestinal stromal tumorsJussuf T Kaifi
Department of General, Visceral and Thoracic Surgery, University Medical Center Hamburg Eppendorf, D 20246 Hamburg, Germany
Oncol Rep 16:915-9. 2006..05 by log-rank test; median follow-up time 37 months). LOH of Hox11L1 gene locus is a useful parameter for prognosis of GIST. The data propose that Hox11L1 has a role in tumorigenesis in GISTs... - Complementary use of fluorescence and magnetic resonance imaging of metastatic esophageal cancer in a novel orthotopic mouse modelStephanie J Gros
Department of General, Visceral, and Thoracic Surgery, University Medical Center Hamburg Eppendorf, Hamburg, Germany
Int J Cancer 126:2671-81. 2010..This model should prove highly useful to understand esophageal carcinoma and to identify novel therapeutics for this treatment-resistant disease... - L1 (CD171) is highly expressed in gastrointestinal stromal tumorsJussuf T Kaifi
Department of General, Visceral and Thoracic Surgery, University Medical Center Hamburg Eppendorf, Hamburg, Germany
Mod Pathol 19:399-406. 2006..The trend towards a reduced survival of L1-positive patients in this study has to be further evaluated in future trials with higher patient numbers... - Frequent homogeneous HER-2 amplification in primary and metastatic adenocarcinoma of the esophagusUta Reichelt
Department of Pathology, University Medical Center Hamburg Eppendorf, University of Hamburg, Hamburg, Germany
Mod Pathol 20:120-9. 2007..The strong concordance of the HER-2 status in primary and metastatic cancers argues for a possible response of metastases from patients with HER-2-positive primary tumors to Herceptin... - Effectiveness of radical en-bloc-esophagectomy compared to transhiatal esophagectomy in squamous cell cancer of the esophagus is influenced by nodal micrometastasesEmre F Yekebas
Department of General, Visceral and Thoracic Surgery at the University Medical Center Hamburg-Eppendorf, University of Hamburg, Hamburg, Germany
J Surg Oncol 93:541-9. 2006..333). CONCLUSION: TTE results in improved outcome in the absence of lymph node micrometastases. Poor survival in patients with lymphatic micro-dissemination indicates systemic disease and the need for adjuvant treatment... - L1 is a potential marker for poorly-differentiated pancreatic neuroendocrine carcinomaJussuf T Kaifi
Department of General, Visceral and Thoracic Surgery, University Medical Center Hamburg Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany
World J Gastroenterol 12:94-8. 2006..To determine the expression of L1 in pancreatic neuroendocrine tumor and to correlate it with WHO classification of this tumor... - Monitoring of loss of heterozygosity in serum microsatellite DNA among patients with gastrointestinal stromal tumors indicates tumor recurrenceTamina Rawnaq
Department of General, Visceral and Thoracic Surgery, University Medical Center Hamburg Eppendorf, Hamburg, Germany
J Surg Res 169:31-5. 2011..In the current study, the aim was to investigate whether the frequency of loss of heterozygosity (LOH) on cell-free DNA in blood may reflect tumor stage and recurrent disease of these patients... - Postpancreatectomy hemorrhage: diagnosis and treatment: an analysis in 1669 consecutive pancreatic resectionsEmre F Yekebas
Department of General, Visceral and Thoracic Surgery, University Medical Centre Hamburg Eppendorf, University of Hamburg, Hamburg, Germany
Ann Surg 246:269-80. 2007..To analyze clinical courses and outcome of postpancreatectomy hemorrhage (PPH) after major pancreatic surgery... - The role of vascular adhesion molecules PECAM-1 (CD 31), VCAM-1 (CD 106), E-selectin (CD62E) and P-selectin (CD62P) in severe porcine pancreatitisHelge Kleinhans
Department of General, Visceral and Thoracic Surgery, University Medical Center Hamburg Eppendorf, Hamburg, Germany
Histol Histopathol 24:551-7. 2009..The endothelial cell expression of CD 31 (PECAM-1), CD 106 (VCAM), CD 62E (E-Selectin) and CD 62P (P-SELECTIN) in severe porcine pancreatitis is detectable and upregulation is partly significantly... - Oxygen radical formation does not have an impact in the treatment of severe acute experimental pancreatitis using free cellular hemoglobinHelge Kleinhans
Department of General, Visceral- and Thoracic Surgery, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, D-20246 Hamburg, Germany
World J Gastroenterol 12:2914-8. 2006..The beneficial effect of additional oxygen supply (HBOC-200) does not lead to enhanced lipid peroxidation... - L1 is associated with favorable outcome in neuroblastomas in contrast to adult tumorsRobin Wachowiak
Department of Pediatric Surgery, University Medical Center, 04103, Leipzig, Germany
Ann Surg Oncol 14:3575-80. 2007..L1, a neuronal cell adhesion molecule, is associated with poor survival in malignant adult tumors. The aim of the current study was to determine expression of L1 in pediatric neuroblastoma...