Henning Schulze-Bergkamen

Summary

Affiliation: University of Mainz
Country: Germany

Publications

  1. doi request reprint Novel ways to sensitise gastrointestinal cancer to apoptosis
    H Schulze-Bergkamen
    First Medical Department, University of Mainz, Langenbeckstrasse 1, D 55101 Mainz, Germany
    Gut 58:1010-24. 2009
  2. pmc Bcl-x(L) and Myeloid cell leukaemia-1 contribute to apoptosis resistance of colorectal cancer cells
    Henning Schulze-Bergkamen
    First Department of Medicine, Johannes Gutenberg University Mainz, Mainz, Germany
    World J Gastroenterol 14:3829-40. 2008
  3. pmc Suppression of Mcl-1 via RNA interference sensitizes human hepatocellular carcinoma cells towards apoptosis induction
    Henning Schulze-Bergkamen
    First Department of Medicine, Johannes Gutenberg University Mainz, Langenbeckstrasse 1, 55101 Mainz, Germany
    BMC Cancer 6:232. 2006
  4. pmc TRAIL-induced apoptosis of hepatocellular carcinoma cells is augmented by targeted therapies
    Bruno Christian Koehler
    First Department of Medicine, Johannes Gutenberg University Mainz, 55101 Mainz, Germany
    World J Gastroenterol 15:5924-35. 2009
  5. ncbi request reprint Mcl-1 is an anti-apoptotic factor for human hepatocellular carcinoma
    Binje Fleischer
    I Department of Medicine, Johannes Gutenberg University Mainz, 55101 Mainz, Germany
    Int J Oncol 28:25-32. 2006
  6. pmc Knockout of myeloid cell leukemia-1 induces liver damage and increases apoptosis susceptibility of murine hepatocytes
    Binje Vick
    1st Department of Medicine, Johannes Gutenberg University Mainz, Germany
    Hepatology 49:627-36. 2009
  7. doi request reprint The impact of patient and tumour baseline characteristics on the overall survival of patients with advanced hepatocellular carcinoma treated with sorafenib
    Marcus A Wörns
    Department of Internal Medicine I, University Medical Center of the Johannes Gutenberg University, Mainz, Germany
    Dig Liver Dis 45:408-13. 2013
  8. doi request reprint IFN-alpha-induced apoptosis in hepatocellular carcinoma involves promyelocytic leukemia protein and TRAIL independently of p53
    Kerstin Herzer
    Department of Medicine, Johannes Gutenberg University, Mainz, Germany
    Cancer Res 69:855-62. 2009
  9. ncbi request reprint Genetics of hepatocellular carcinoma
    Andreas Teufel
    Department of Medicine, Johannes Gutenberg University, Building 301, Langenbeckstr 1, 55101 Mainz, Germany
    World J Gastroenterol 13:2271-82. 2007
  10. ncbi request reprint Down-regulation of CYLD as a trigger for NF-κB activation and a mechanism of apoptotic resistance in hepatocellular carcinoma cells
    Toni Urbanik
    First Department of Medicine, Johannes Gutenberg University, Mainz, Germany
    Int J Oncol 38:121-31. 2011

Collaborators

Detail Information

Publications12

  1. doi request reprint Novel ways to sensitise gastrointestinal cancer to apoptosis
    H Schulze-Bergkamen
    First Medical Department, University of Mainz, Langenbeckstrasse 1, D 55101 Mainz, Germany
    Gut 58:1010-24. 2009
    ..In this review, the current knowledge on defects in apoptosis signalling in GI cancer is summarised and the focus is on the potential clinical efficacy of apoptosis targeting agents...
  2. pmc Bcl-x(L) and Myeloid cell leukaemia-1 contribute to apoptosis resistance of colorectal cancer cells
    Henning Schulze-Bergkamen
    First Department of Medicine, Johannes Gutenberg University Mainz, Mainz, Germany
    World J Gastroenterol 14:3829-40. 2008
    ..To explore the role of Bcl-x(L) and Myeloid cell leukaemia (Mcl)-1 for the apoptosis resistance of colorectal carcinoma (CRC) cells towards current treatment modalities...
  3. pmc Suppression of Mcl-1 via RNA interference sensitizes human hepatocellular carcinoma cells towards apoptosis induction
    Henning Schulze-Bergkamen
    First Department of Medicine, Johannes Gutenberg University Mainz, Langenbeckstrasse 1, 55101 Mainz, Germany
    BMC Cancer 6:232. 2006
    ..In this study, we manipulated expression of the Mcl-1 protein in HCC cells by RNA interference and analyzed its impact on apoptosis sensitivity of HCC cells in vitro...
  4. pmc TRAIL-induced apoptosis of hepatocellular carcinoma cells is augmented by targeted therapies
    Bruno Christian Koehler
    First Department of Medicine, Johannes Gutenberg University Mainz, 55101 Mainz, Germany
    World J Gastroenterol 15:5924-35. 2009
    ....
  5. ncbi request reprint Mcl-1 is an anti-apoptotic factor for human hepatocellular carcinoma
    Binje Fleischer
    I Department of Medicine, Johannes Gutenberg University Mainz, 55101 Mainz, Germany
    Int J Oncol 28:25-32. 2006
    ..Our data suggest that Mcl-1 is an important factor for the apoptosis resistance of human HCC, and constitutes an interesting target for HCC therapy...
  6. pmc Knockout of myeloid cell leukemia-1 induces liver damage and increases apoptosis susceptibility of murine hepatocytes
    Binje Vick
    1st Department of Medicine, Johannes Gutenberg University Mainz, Germany
    Hepatology 49:627-36. 2009
    ..Conclusion: The present study provides in vivo evidence that Mcl-1 is a crucial antiapoptotic factor for the liver, contributing to hepatocellular homeostasis and protecting hepatocytes from apoptosis induction...
  7. doi request reprint The impact of patient and tumour baseline characteristics on the overall survival of patients with advanced hepatocellular carcinoma treated with sorafenib
    Marcus A Wörns
    Department of Internal Medicine I, University Medical Center of the Johannes Gutenberg University, Mainz, Germany
    Dig Liver Dis 45:408-13. 2013
    ..Impact of patient and tumour baseline characteristics on the overall survival is not well characterized in patients with advanced hepatocellular carcinoma (HCC) treated with sorafenib...
  8. doi request reprint IFN-alpha-induced apoptosis in hepatocellular carcinoma involves promyelocytic leukemia protein and TRAIL independently of p53
    Kerstin Herzer
    Department of Medicine, Johannes Gutenberg University, Mainz, Germany
    Cancer Res 69:855-62. 2009
    ....
  9. ncbi request reprint Genetics of hepatocellular carcinoma
    Andreas Teufel
    Department of Medicine, Johannes Gutenberg University, Building 301, Langenbeckstr 1, 55101 Mainz, Germany
    World J Gastroenterol 13:2271-82. 2007
    ..Furthermore, we describe the influence of chromosomal aberrations as well as of DNA methylation. Finally, we report on the rapidly developing field of genomic expression profiling in HCC, mainly by microarray analysis...
  10. ncbi request reprint Down-regulation of CYLD as a trigger for NF-κB activation and a mechanism of apoptotic resistance in hepatocellular carcinoma cells
    Toni Urbanik
    First Department of Medicine, Johannes Gutenberg University, Mainz, Germany
    Int J Oncol 38:121-31. 2011
    ..Our data identify the reconstitution of CYLD expression as an attractive approach for overcoming resistance to treatment in HCC...
  11. doi request reprint Safety and efficacy of sorafenib in patients with advanced hepatocellular carcinoma in consideration of concomitant stage of liver cirrhosis
    Marcus Alexander Wörns
    I Department of Internal Medicine, Johannes Gutenberg University Mainz, Germany
    J Clin Gastroenterol 43:489-95. 2009
    ..We report our experiences with sorafenib in advanced HCC, particularly in patients with LCI Child-Pugh B/C, where only limited data are available in regard to safety and efficacy of sorafenib...
  12. ncbi request reprint The role of apoptosis versus oncotic necrosis in liver injury: facts or faith?
    Henning Schulze-Bergkamen
    Department of Medicine, Johannes Gutenberg University, Langenbeckstrasse 1, Mainz 55101, Germany
    J Hepatol 44:984-93. 2006