Stefan Schulte Merker
Affiliation: University Hospital
Karpanen T, Padberg Y, van de Pavert S, Dierkes C, Morooka N, Peterson Maduro J, et al
. An Evolutionarily Conserved Role for Polydom/Svep1 During Lymphatic Vessel Formation. Circ Res. 2017;120:1263-1275 pubmed publisher
Mauri C, Wang G, Schulte Merker S. From fish embryos to human patients: lymphangiogenesis in development and disease. Curr Opin Immunol. 2018;53:167-172 pubmed publisher
..Here, we focus on components of the Vegfr3 pathway, and how they are connected to Milroy disease and Hennekam syndrome. ..
Mackay E, Apschner A, Schulte Merker S. Vitamin K reduces hypermineralisation in zebrafish models of PXE and GACI. Development. 2015;142:1095-101 pubmed publisher
..Additionally, we found that abcc6a is strongly expressed at the site of mineralisation rather than the liver, as it is in mammals, which has significant implications for our understanding of the function of ABCC6. ..
Hermkens D, van Impel A, Urasaki A, Bussmann J, Duckers H, Schulte Merker S. Sox7 controls arterial specification in conjunction with hey2 and efnb2 function. Development. 2015;142:1695-704 pubmed publisher
..Hence, sox7 levels are crucial in arterial specification in conjunction with hey2 and efnb2 function, with mutants in all three genes displaying shunt formation and an arterial block. ..
Hogan B, Schulte Merker S. How to Plumb a Pisces: Understanding Vascular Development and Disease Using Zebrafish Embryos. Dev Cell. 2017;42:567-583 pubmed publisher
..Here, we highlight key mechanisms controlling formation of the zebrafish vasculature and investigate how knowledge from this highly tractable model system has informed our understanding of vascular disease in humans. ..