P Schuff-Werner

Summary

Affiliation: University of Rostock
Country: Germany

Publications

  1. ncbi request reprint [Plaque stabilization by LDL apheresis?]
    P Schuff-Werner
    Institut fur Klinische Chemie und Pathobiochemie, Medizinische Fakultat, Universitat Rostock
    Herz 24:57-61. 1999
  2. pmc Effective estimation of correct platelet counts in pseudothrombocytopenia using an alternative anticoagulant based on magnesium salt
    Peter Schuff-Werner
    Institute of Clinical Chemistry and Laboratory Medicine, Rostock University Medical Centre, Rostock, Germany
    Br J Haematol 162:684-92. 2013
  3. pmc Role of lipid apheresis in changing times
    Peter Schuff-Werner
    Institut fur Klinische Chemie und Laboratoriumsmedizin, Universitätsmedizin Rostock, Ernst Heydemann Straße 6, 18057 Rostock, Germany
    Clin Res Cardiol Suppl 7:7-14. 2012
  4. ncbi request reprint Antioxidative properties of serotonin and the bactericidal function of polymorphonuclear phagocytes
    P Schuff-Werner
    Institute of Clinical Chemistry and Pathobiochemistry, University of Rostock, Medical Faculty, Germany
    Adv Exp Med Biol 467:321-5. 1999
  5. ncbi request reprint [Possible value of positive PSA levels in malignant and nonmalignant breast diseases]
    P Schuff-Werner
    Institut fur Klinische Chemie und Pathobiochemie, Medizinische Fakultät Rostock
    Onkologie 24:11-7. 2001
  6. ncbi request reprint [Clinical long-term results of H.E.L.P.-apheresis]
    P Schuff-Werner
    Universität Rostock Institut für Klinische Chemie, Ernst Heydemann Str 6, 18055 Rostock, Germany
    Z Kardiol 92:III28-9. 2003
  7. ncbi request reprint Selective hemapheresis, an effective new approach in the therapeutic management of disorders associated with rheological impairment: mode of action and possible clinical indications
    Peter Schuff-Werner
    Medical Faculty, Institute of Clinical Chemistry and Pathobiochemistry, University of Rostock, Germany
    Artif Organs 26:117-23. 2002
  8. ncbi request reprint 609 C --> T polymorphism in NAD(P)H:quinone oxidoreductase gene in patients with prostatic adenocarcinoma or benign prostatic hyperplasia
    M Steiner
    Institute of Clinical Chemistry and Pathobiochemistry, Faculty of Medicine, University of Rostock, Germany
    Cancer Lett 135:67-71. 1999
  9. ncbi request reprint Dysregulation of the calpain-calpastatin system plays a role in the development of cerulein-induced acute pancreatitis in the rat
    Heike Weber
    Institute of Clinical Chemistry and Pathobiochemistry, University of Rostock, Germany
    Am J Physiol Gastrointest Liver Physiol 286:G932-41. 2004
  10. ncbi request reprint Comparative evaluation of two newly developed devices for capillary viscometry
    Birgit Holdt
    Institute of Clinical Chemistry and Laboratory Medicine, University of Rostock, Medical Faculty, Germany
    Clin Hemorheol Microcirc 33:379-87. 2005

Collaborators

Detail Information

Publications39

  1. ncbi request reprint [Plaque stabilization by LDL apheresis?]
    P Schuff-Werner
    Institut fur Klinische Chemie und Pathobiochemie, Medizinische Fakultat, Universitat Rostock
    Herz 24:57-61. 1999
    ..The affinity of different LDL-apheresis procedures to coagulation factors normalizes hypercoagulatory states thus avoiding atherothrombotic events at the site of vulnerable or erosive plaques...
  2. pmc Effective estimation of correct platelet counts in pseudothrombocytopenia using an alternative anticoagulant based on magnesium salt
    Peter Schuff-Werner
    Institute of Clinical Chemistry and Laboratory Medicine, Rostock University Medical Centre, Rostock, Germany
    Br J Haematol 162:684-92. 2013
    ..We conclude that in patients with known or suspected pseudothrombocytopenia the magnesium-anticoagulant blood samples may be recommended for platelet counting. ..
  3. pmc Role of lipid apheresis in changing times
    Peter Schuff-Werner
    Institut fur Klinische Chemie und Laboratoriumsmedizin, Universitätsmedizin Rostock, Ernst Heydemann Straße 6, 18057 Rostock, Germany
    Clin Res Cardiol Suppl 7:7-14. 2012
    ....
  4. ncbi request reprint Antioxidative properties of serotonin and the bactericidal function of polymorphonuclear phagocytes
    P Schuff-Werner
    Institute of Clinical Chemistry and Pathobiochemistry, University of Rostock, Medical Faculty, Germany
    Adv Exp Med Biol 467:321-5. 1999
    ..At appropriate concentrations, the antibacterial defence improves significantly probably due to reduced autooxidation, whereas higher concentrations counteract an efficient bacterial killing...
  5. ncbi request reprint [Possible value of positive PSA levels in malignant and nonmalignant breast diseases]
    P Schuff-Werner
    Institut fur Klinische Chemie und Pathobiochemie, Medizinische Fakultät Rostock
    Onkologie 24:11-7. 2001
    ..There are some findings which might indicate similarities in the influence of steroid hormones on the development of prostate and breast malignancies, perhaps a unique hormone-dependent molecular pathway for both types of cancer...
  6. ncbi request reprint [Clinical long-term results of H.E.L.P.-apheresis]
    P Schuff-Werner
    Universität Rostock Institut für Klinische Chemie, Ernst Heydemann Str 6, 18055 Rostock, Germany
    Z Kardiol 92:III28-9. 2003
    ..Therefore, the incidence of adverse effects directly attributable to HELP does not exceed 1-2%...
  7. ncbi request reprint Selective hemapheresis, an effective new approach in the therapeutic management of disorders associated with rheological impairment: mode of action and possible clinical indications
    Peter Schuff-Werner
    Medical Faculty, Institute of Clinical Chemistry and Pathobiochemistry, University of Rostock, Germany
    Artif Organs 26:117-23. 2002
    ....
  8. ncbi request reprint 609 C --> T polymorphism in NAD(P)H:quinone oxidoreductase gene in patients with prostatic adenocarcinoma or benign prostatic hyperplasia
    M Steiner
    Institute of Clinical Chemistry and Pathobiochemistry, Faculty of Medicine, University of Rostock, Germany
    Cancer Lett 135:67-71. 1999
    ..Our study does not support the hypothesis that the variant NQO1 allele is a risk modifier for prostatic adenocarcinoma and/or benign prostatic hyperplasia in the Caucasian population...
  9. ncbi request reprint Dysregulation of the calpain-calpastatin system plays a role in the development of cerulein-induced acute pancreatitis in the rat
    Heike Weber
    Institute of Clinical Chemistry and Pathobiochemistry, University of Rostock, Germany
    Am J Physiol Gastrointest Liver Physiol 286:G932-41. 2004
    ..05), histological score for eight parameters (P < 0.01), and actin filament alterations. Our findings support the hypothesis that dysregulation of the calpain-calpastatin system may play a role in the onset of acute pancreatitis...
  10. ncbi request reprint Comparative evaluation of two newly developed devices for capillary viscometry
    Birgit Holdt
    Institute of Clinical Chemistry and Laboratory Medicine, University of Rostock, Medical Faculty, Germany
    Clin Hemorheol Microcirc 33:379-87. 2005
    ..4+/-3.6%. We conclude that both new devices for viscosity assessment fulfill all quality requirements as prescribed for clinical chemical laboratories. One advantage RFV is to measure the dynamic viscosity directly...
  11. ncbi request reprint Maternal serum concentrations of BDNF and depression in the perinatal period
    Marek Lommatzsch
    Department of Pneumology, University of Rostock, Ernst Heydemann Strasse 6, 18057 Rostock, Germany
    Psychoneuroendocrinology 31:388-94. 2006
    ..This phenomenon might reflect an increased risk for the development of mood disorders in the perinatal period. However, the individual serum concentration of BDNF alone did not predict maternal depression in our study...
  12. ncbi request reprint The impact of age, weight and gender on BDNF levels in human platelets and plasma
    Marek Lommatzsch
    Department of Pneumology, University of Rostock, Ernst Heydemann Str 6, 18057 Rostock, Germany
    Neurobiol Aging 26:115-23. 2005
    ..In addition, platelet BDNF levels changed during the menstrual cycle. In conclusion, we demonstrate that parameters such as age or gender have a specific impact on stored and circulating BDNF levels in peripheral blood...
  13. ncbi request reprint Expression of thrombospondin-1 in prostate-derived cell lines
    Manuela Bastian
    University of Rostock, Institute of Clinical Chemistry and Pathobiochemistry, D 18057 Rostock, Germany
    Int J Mol Med 15:49-56. 2005
    ..In addition, TSP-1 located at the border between tumor and stroma as observed in primary prostate tumors may act as a barrier of tumor growth depending on the TSP-1 receptor repertoire of the tumor cells...
  14. ncbi request reprint Improvement of early vascular changes and cardiovascular risk factors in obese children after a six-month exercise program
    Andreas A Meyer
    Division of Pediatric Cardiology, Children s Hospital, University of Rostock, Rostock, Germany
    J Am Coll Cardiol 48:1865-70. 2006
    ..The present study aimed to assess the effect of a 6-month exercise program in obese children on flow-mediated vasodilation (FMD) carotid intima-media thickness (IMT) and cardiovascular risk factors (RF)...
  15. ncbi request reprint Brain-derived neurotrophic factor in platelets and airflow limitation in asthma
    Marek Lommatzsch
    Department of Pneumology and Institute of Clinical Chemistry and Pathobiochemistry, University of Rostock, Rostock, Germany
    Am J Respir Crit Care Med 171:115-20. 2005
    ..In addition, we provide evidence that corticosteroids suppress BDNF production by activated immune cells...
  16. ncbi request reprint Platelet and plasma BDNF in lower respiratory tract infections of the adult
    Marek Lommatzsch
    Department of Pneumology, University of Rostock, 18057 Rostock, Germany
    Respir Med 101:1493-9. 2007
    ..In conclusion, these data suggest that lower respiratory tract infections might be associated with an augmented release of BDNF by platelets and mononuclear cells...
  17. ncbi request reprint Impaired flow-mediated vasodilation, carotid artery intima-media thickening, and elevated endothelial plasma markers in obese children: the impact of cardiovascular risk factors
    Andreas Alexander Meyer
    Division of Pediatric Cardiology, Childrens Hospital, University of Rostock, Rostock, Germany
    Pediatrics 117:1560-7. 2006
    ..Associations between early morphologic and functional vascular changes, surrogate soluble markers of early atherosclerosis, and the cardiovascular risk profile were determined...
  18. ncbi request reprint Expression and regulation of calpain in rat pancreatic acinar cells
    Heike Weber
    Institute of Clinical Chemistry and Pathobiochemistry, University of Rostock, Rostock, Germany
    Pancreas 24:63-74. 2002
    ..Calpains, cytosolic Ca(2+)-dependent cysteine proteases, are expressed in a variety of mammalian cells and have been found to participate in stimulus-secretion coupling in platelets and alveolar cells...
  19. ncbi request reprint Hydrogen peroxide-induced activation of defense mechanisms against oxidative stress in rat pancreatic acinar AR42J cells
    Heike Weber
    Institute of Clinical Chemistry and Laboratory Medicine, University of Rostock, Ernst Heydemann Strasse 6, 18057 Rostock, Germany
    Free Radic Biol Med 42:830-41. 2007
    ..An understanding of the cellular stress responses may lead to new insights into the pathogenesis of oxidative stress-related diseases including acute pancreatitis...
  20. ncbi request reprint Expression of functional protease-activated receptor 1 in human prostate cancer cell lines
    Jian Liu
    University of Rostock, Medical Faculty, Institute of Clinical Chemistry and Pathobiochemistry, Ernst Heydemann Strasse 6, 18057 Rostock, Germany
    Urol Res 31:163-8. 2003
    ..In contrast, 1.0 U/ml thrombin caused earlier inhibition of DU 145 proliferation starting at 48 h of incubation. Our results suggest that PAR-1 mediates the proliferation-modulating effects of thrombin on prostate cancer cells...
  21. doi request reprint Calpain mediates caspase-dependent apoptosis initiated by hydrogen peroxide in pancreatic acinar AR42J cells
    H Weber
    Institute of Clinical Chemistry and Laboratory Medicine, University of Rostock, Rostock, Germany
    Free Radic Res 47:432-46. 2013
    ..The findings also suggest that calpain may be involved in the execution phase of apoptosis...
  22. ncbi request reprint Phenol sulphotransferase SULT1A1 polymorphism in prostate cancer: lack of association
    M Steiner
    Institut fur Klinische Chemie und Pathobiochemie, Medizinische Fakultat, Universitat Rostock, Germany
    Arch Toxicol 74:222-5. 2000
    ..7% vs 17.4%). Our study does not support the hypothesis that the phenol sulphotransferase variant allele SULT1A1*2 with a G/A transition at nucleotide 638 is a risk modifier for prostate cancer in the Caucasian population...
  23. ncbi request reprint Inositol 1,4,5-trisphosphate formation, cytoplasmic calcium dynamics, and alpha-amylase secretion of pancreatic acini isolated from aged and chronically alcohol-fed rats
    E Siegmund
    Institute of Clinical Chemistry and Pathobiochemistry, Faculty of Medicine, University of Rostock, Germany
    Int J Pancreatol 27:39-50. 2000
    ..Acinar alpha-amylase (Aml) secretion was measured as enzyme activity in the medium compared to the total activity in the suspension...
  24. ncbi request reprint [Current therapy of hypercholesterolemia. How much statin does your patient need?]
    P Schuff-Werner
    Institut fur Klinische Chemie und Pathobiochemie, Universitat Rostock
    MMW Fortschr Med 144:24-6. 2002
    ..To minimize the side effects of statin treatment, therefore, target levels--which must be derived on the basis of the results of large studies--must be established for the individual patient...
  25. ncbi request reprint Hemochromatosis gene HFE Cys282Tyr mutation analysis in a cohort of Northeast German hospitalized patients supports assumption of a North to South allele frequency gradient throughout Germany
    Patrick Meier
    Institute of Clinical Chemistry and Laboratory Medicine, University of Rostock, Germany
    Clin Lab 51:539-43. 2005
    ..44% and supports the emerging concept of an allele gradient decreasing from North to South within Germany...
  26. doi request reprint Renal Insufficiency Following Radiocontrast Exposure Trial (REINFORCE): a randomized comparison of sodium bicarbonate versus sodium chloride hydration for the prevention of contrast-induced nephropathy
    Esther Adolph
    Division of Cardiology, Department of Internal Medicine, University of Rostock, Germany
    Coron Artery Dis 19:413-9. 2008
    ..The aim of this study was to analyze and compare the effects of sodium bicarbonate and sodium chloride on renal function in 145 patients exposed to nonionic iso-osmolar contrast medium iodixanol in a randomized study...
  27. ncbi request reprint Contact activation in low-density lipoprotein apheresis systems
    Detlef H Krieter
    Department of Nephrology, University of Wurzburg, Wurzburg, Germany
    Artif Organs 29:47-52. 2005
    ....
  28. ncbi request reprint Oxidative stress in phagocytes--"the enemy within"
    Wolf D Splettstoesser
    German Armed Forces Medical Academy, Institute of Microbiology, D 80937 Munich, Germany
    Microsc Res Tech 57:441-55. 2002
    ....
  29. ncbi request reprint Double transfection improves small interfering RNA-induced thrombin receptor (PAR-1) gene silencing in DU 145 prostate cancer cells
    Jian Liu
    Faculty of Medicine, Institute of Clinical Chemistry and Pathobiochemistry, University of Rostock, Ernst Heydemann Strasse 6, D 18057 Rostock, Germany
    FEBS Lett 577:175-80. 2004
    ....
  30. ncbi request reprint Giant platelets in idiopathic thrombocytopenic purpura
    Michael Steiner
    Institut fur Klinische Chemie und Pathobiochemie, Universitat Rostock, Ernst Heydemann Str 6, D 18057 Rostock, Germany
    Wien Klin Wochenschr 114:897. 2002
  31. ncbi request reprint Balancing analytical performance and medical reasoning: is carryover a critical issue in estimating low white blood cell numbers in bone marrow/stem cell transplant recipients?
    Michael Steiner
    Institute of Clinical Chemistry and Pathobiochemistry, University of Rostock, Ernst Heydemann Strasse 6, 18057 Rostock, Germany
    Ann Hematol 83:256-7. 2004
  32. ncbi request reprint Thrombin/thrombin receptor (PAR-1)-mediated induction of IL-8 and VEGF expression in prostate cancer cells
    Jian Liu
    University of Rostock, Institute of Clinical Chemistry and Laboratory Medicine, Ernst Heydemann Str 6, D 18057 Rostock, Germany
    Biochem Biophys Res Commun 343:183-9. 2006
    ..The results suggest that the thrombin/PAR-1 system upregulates cytokines in prostate cancer cells which in turn may contribute to the progression of prostate cancer...
  33. ncbi request reprint Multicentre performance evaluation of the E170 module for modular analytics
    Christian Bieglmayer
    Klinisches Institut für Medizinische und Chemische Labordiagnostik, AKH Wien, Vienna, Austria
    Clin Chem Lab Med 42:1186-202. 2004
    ..Throughput and sample processing time requirements were achieved while personnel 'hands-on-time' could be reduced...
  34. ncbi request reprint The European Register for Specialists in Clinical Chemistry and Laboratory Medicine: Code of Conduct
    Gerard Sanders
    Department of Clinical Chemistry, Academic Medical Center, Amsterdam, The Netherlands
    Clin Chem Lab Med 42:563-5. 2004
    ..In this article a Code of Conduct for Registrants which was approved at the EC4 Register Committee meeting in Amsterdam, 8 November 2003 is presented...
  35. ncbi request reprint Aptamer and inhibition of thrombin clotting activity: a note of caution
    Jian Liu
    Thromb Res 107:281-2. 2002
  36. ncbi request reprint Comparison of two filter combinations for low-density lipoprotein apheresis by membrane differential filtration: a prospective crossover controlled clinical study
    Goran Matic
    Labor Müller, Rostock, Germany
    Artif Organs 26:371-7. 2002
    ..In conclusion, despite similar physical properties, the membranes differ significantly concerning selectivity and sensitivity to saturation...
  37. ncbi request reprint Elevated serum pancreatic enzyme activities in kidney transplant recipients and azathioprine drug therapy: is thiopurine methyltransferase polymorphism one missing link?
    Michael Steiner
    Urol Int 68:135-6. 2002
  38. ncbi request reprint A homozygous HFE gene splice site mutation (IVS5+1 G/A) in a hereditary hemochromatosis patient of Vietnamese origin
    Michael Steiner
    Institute of Clinical Chemistry and Pathobiochemistry, University of Rostock, Rostock, Germany
    Gastroenterology 122:789-95. 2002
    ....
  39. ncbi request reprint Combined chemotherapy trials require combined pharmacogenetic approaches
    Michael Steiner
    J Clin Oncol 20:1425-6. 2002