Oliver Schnell

Summary

Affiliation: University of Munich
Country: Germany

Publications

  1. pmc Type 1 diabetes and cardiovascular disease
    Oliver Schnell
    Forschergruppe Diabetes e, V, Helmholtz Center Munich, Ingolstaedter Landstrasse 1, 85764 Munich Neuherberg, Germany
    Cardiovasc Diabetol 12:156. 2013
  2. pmc Assessing the analytical performance of systems for self-monitoring of blood glucose: concepts of performance evaluation and definition of metrological key terms
    Oliver Schnell
    Forschergruppe Diabetes e V, Helmholtz Center Munich, Ingolstaedter Landstrasse 1, 85764 Munich Neuherberg, Germany
    J Diabetes Sci Technol 7:1585-94. 2013
  3. pmc Higher accuracy of self-monitoring of blood glucose in insulin-treated patients in Germany: clinical and economical aspects
    Oliver Schnell
    Forschergruppe Diabetes e V, Helmholtz Center Munich, Munich Neuherberg, Germany
    J Diabetes Sci Technol 7:904-12. 2013
  4. pmc Changes in A1C levels are significantly associated with changes in levels of the cardiovascular risk biomarker hs-CRP: results from the SteP study
    Oliver Schnell
    Forschergruppe Diabetes e V, Helmholtz Center Munich, Munich, Germany
    Diabetes Care 36:2084-9. 2013
  5. pmc Self-monitoring of blood glucose in type 2 diabetes: recent studies
    Oliver Schnell
    Forschergruppe Diabetes e V at the Helmholtz Center Munich, Ingolstadter Landstrasse 1, 85764 Munich Neuherberg, Germany
    J Diabetes Sci Technol 7:478-88. 2013
  6. ncbi request reprint Primary and secondary prevention of cardiovascular disease in diabetes with aspirin
    Oliver Schnell
    Diabetes Research Group, Helmholtz Centre Munich, Neuherberg, Germany
    Diab Vasc Dis Res 9:245-55. 2012
  7. pmc The role of self-monitoring of blood glucose in glucagon-like peptide-1-based treatment approaches: a European expert recommendation
    Oliver Schnell
    Diabetes Research Group, Helmholtz Center, Munich, Germany
    J Diabetes Sci Technol 6:665-73. 2012
  8. ncbi request reprint [Glucose control in cardiac disease]
    O Schnell
    Institut fur Diabetesforschung, Kolner Platz 1, 80804 München
    Clin Res Cardiol 95:i70-3. 2006
  9. doi request reprint Addressing schemes of self-monitoring of blood glucose in type 2 diabetes: a European perspective and expert recommendation
    Oliver Schnell
    Diabetes Research Group, Helmholtz Center, Munich Neuherberg, Germany
    Diabetes Technol Ther 13:959-65. 2011
  10. ncbi request reprint Cardiac sympathetic innervation and blood flow regulation of the diabetic heart
    O Schnell
    Diabetes Reseach Institute, Kolner Platz 1, 80804 Munich, Germany
    Diabetes Metab Res Rev 17:243-5. 2001

Collaborators

Detail Information

Publications51

  1. pmc Type 1 diabetes and cardiovascular disease
    Oliver Schnell
    Forschergruppe Diabetes e, V, Helmholtz Center Munich, Ingolstaedter Landstrasse 1, 85764 Munich Neuherberg, Germany
    Cardiovasc Diabetol 12:156. 2013
    ..Future therapies may also include glucagon-like peptide (GLP)-based treatment therapies. Pilot studies with GLP-1-analogues have been shown to reduce insulin requirements. ..
  2. pmc Assessing the analytical performance of systems for self-monitoring of blood glucose: concepts of performance evaluation and definition of metrological key terms
    Oliver Schnell
    Forschergruppe Diabetes e V, Helmholtz Center Munich, Ingolstaedter Landstrasse 1, 85764 Munich Neuherberg, Germany
    J Diabetes Sci Technol 7:1585-94. 2013
    ..In addition, a description of requirements and components for a sound evaluation of BG measurement systems is presented. These factors will also enable improvement in future comparisons of study results. ..
  3. pmc Higher accuracy of self-monitoring of blood glucose in insulin-treated patients in Germany: clinical and economical aspects
    Oliver Schnell
    Forschergruppe Diabetes e V, Helmholtz Center Munich, Munich Neuherberg, Germany
    J Diabetes Sci Technol 7:904-12. 2013
    ..Regarding clinical and financial impact of BG meter accuracy, very little data are available. The aim of this study was to analyze potential cost savings related to higher accuracy of glucose meters in Germany...
  4. pmc Changes in A1C levels are significantly associated with changes in levels of the cardiovascular risk biomarker hs-CRP: results from the SteP study
    Oliver Schnell
    Forschergruppe Diabetes e V, Helmholtz Center Munich, Munich, Germany
    Diabetes Care 36:2084-9. 2013
    ....
  5. pmc Self-monitoring of blood glucose in type 2 diabetes: recent studies
    Oliver Schnell
    Forschergruppe Diabetes e V at the Helmholtz Center Munich, Ingolstadter Landstrasse 1, 85764 Munich Neuherberg, Germany
    J Diabetes Sci Technol 7:478-88. 2013
    ..The aim of this article is to review key publications on SMBG and also to put them into perspective with regard to results of the Cochrane review and current aspects of diabetes management...
  6. ncbi request reprint Primary and secondary prevention of cardiovascular disease in diabetes with aspirin
    Oliver Schnell
    Diabetes Research Group, Helmholtz Centre Munich, Neuherberg, Germany
    Diab Vasc Dis Res 9:245-55. 2012
    ..Novel aspects of aspirin, e.g. its potential role for the prevention of cancer, are also presented...
  7. pmc The role of self-monitoring of blood glucose in glucagon-like peptide-1-based treatment approaches: a European expert recommendation
    Oliver Schnell
    Diabetes Research Group, Helmholtz Center, Munich, Germany
    J Diabetes Sci Technol 6:665-73. 2012
    ..It is considered to play an important role for the optimization of diabetes management in T2DM patients treated with GLP-1-based approaches...
  8. ncbi request reprint [Glucose control in cardiac disease]
    O Schnell
    Institut fur Diabetesforschung, Kolner Platz 1, 80804 München
    Clin Res Cardiol 95:i70-3. 2006
    ..This can be detected even in impaired glucose tolerance and the non-diabetic range. There is evidence that postprandial glycemia is crucial for the extent of cardiovascular risk. This has also been emphasized by the DECODE-study...
  9. doi request reprint Addressing schemes of self-monitoring of blood glucose in type 2 diabetes: a European perspective and expert recommendation
    Oliver Schnell
    Diabetes Research Group, Helmholtz Center, Munich Neuherberg, Germany
    Diabetes Technol Ther 13:959-65. 2011
    ..The expert panel also recommended further evaluation of various schemes for SMBG in type 2 diabetes in clinical studies...
  10. ncbi request reprint Cardiac sympathetic innervation and blood flow regulation of the diabetic heart
    O Schnell
    Diabetes Reseach Institute, Kolner Platz 1, 80804 Munich, Germany
    Diabetes Metab Res Rev 17:243-5. 2001
    ..These mechanisms are currently proposed to lead from early changes to advanced impairment of cardiac function in diabetes...
  11. ncbi request reprint Acarbose and metabolic control in patients with type 2 diabetes with newly initiated insulin therapy
    O Schnell
    Diabetes Research Institute, Munich, Germany
    Diabetes Obes Metab 9:853-8. 2007
    ....
  12. ncbi request reprint [Cardiovascular risk in diabetes--diagnostic and therapeutic aspects]
    O Schnell
    Institut fur Diabetesforschung, 3 Med Klinik, Krankenhaus München Schwabing
    MMW Fortschr Med 146:36-8. 2004
    ..An example of a successful approach for metabolic intervention is glucose-insulin infusion to optimize the metabolic condition during the acute phase...
  13. ncbi request reprint Intensification of therapeutic approaches reduces mortality in diabetic patients with acute myocardial infarction: the Munich registry
    Oliver Schnell
    Diabetes Research Institute, and Third Medical Clinic, Academic Schwabing Hospital, Munich, Germany
    Diabetes Care 27:455-60. 2004
    ..The aim of this study was to improve quality care management and to compare hospital mortality and therapeutic approaches (i.e., PTCA, stenting, GPIIb/IIIa receptor antagonists, glucose-insulin infusion)...
  14. ncbi request reprint Cardiac sympathetic dysinnervation in Type 2 diabetes mellitus with and without ECG-based cardiac autonomic neuropathy
    Oliver Schnell
    Diabetes Research Institute, Third Medical Department, Academic Schwabing City Hospital, Munich, Germany
    J Diabetes Complications 16:220-7. 2002
    ..In Type 2 diabetes mellitus, the posterior myocardium is predominantly affected and the extent of dysinnervation is more pronounced in the presence of ECG-based cardiac autonomic neuropathy...
  15. ncbi request reprint [Diagnosis of acute myocardial infarction in diabetes mellitus. Blood sugar to be tested]
    O Schnell
    Institut fur Diabetesforschung, Krankenhaus München Schwabing
    MMW Fortschr Med 145:35-8. 2003
    ..In diabetics with an acute coronary syndrome, early coronary angiography should also be considered. A multifactorial approach can significantly lower the cardiovascular complication rate...
  16. ncbi request reprint C-reactive protein in diabetic and nondiabetic patients with acute myocardial infarction
    Wolfgang Otter
    Cardiology, Academical Teaching Hospital, Schwabing, Munich, Germany
    Diabetes Care 30:3080-2. 2007
  17. doi request reprint The Munich Myocardial Infarction Registry: impact of C-reactive protein and kidney function on hospital mortality in diabetic patients
    Oliver Schnell
    Diabetes Research Institute, Helmholtz Center, Ingolstadter Landstrasse 1, 85764 Neuherberg, Germany
    Diab Vasc Dis Res 7:225-30. 2010
    ..The aim of this study was to analyse hospital mortality with regards to the presence of diabetes, elevation of C-reactive protein (CRP) levels and impaired kidney function (IKF) on admission...
  18. doi request reprint Dynamic 18F-FET PET in newly diagnosed astrocytic low-grade glioma identifies high-risk patients
    Nathalie L Jansen
    Department of Nuclear Medicine, University of Munich, Munich, Germany
    J Nucl Med 55:198-203. 2014
    ....
  19. doi request reprint The impact of glucose-lowering therapy on cardiovascular outcomes
    Eberhard Standl
    Munich Diabetes Research Institute at the Munich Helmholtz Center, Munich Neuherberg, Germany
    Best Pract Res Clin Endocrinol Metab 23:401-11. 2009
    ..5%, which takes time to tailor (poly-)pharmacotherapy gently to the patient's needs. Drug-specific effects, both advantageous and disadvantageous, of blood-glucose-lowering therapy cannot be excluded currently and warrant further studies...
  20. pmc Postprandial hyperglycemia and glycemic variability: should we care?
    Eberhard Standl
    Munich Diabetes Research Institute, Munich Helmholtz Centre, Munich, Germany
    Diabetes Care 34:S120-7. 2011
    ..e., that we should care about postprandial hyperglycemia and glycemic variability. The absence of a uniformly accepted standard of how to estimate these parameters adds a further challenge to this whole debate...
  21. doi request reprint Diabetes and the risk for colorectal cancer
    Michael Erbach
    Diabetes Research Group, Helmholtz Center, Munich Neuherberg, Germany
    J Diabetes Complications 26:50-5. 2012
    ..Finally, the preventive potential of aspirin and other nonsteroidal anti-inflammatory drugs, and the recommendations concerning colonoscopy-screening are presented...
  22. doi request reprint ALDH1A1 is a marker of astrocytic differentiation during brain development and correlates with better survival in glioblastoma patients
    S Alexandra Adam
    Center for Neuropathology and Prion Research, Munich, Germany
    Brain Pathol 22:788-97. 2012
    ..01). In contrast to other published data, we therefore provide evidence for ALDH1A1 as a marker of astrocytic differentiation during brain development and of better prognosis in patients suffering from primary glioblastoma...
  23. doi request reprint Re-irradiation in recurrent malignant glioma: prognostic value of [18F]FET-PET
    Maximilian Niyazi
    Department of Radiation Oncology, Ludwig Maximilians University Munich, Marchioninistr 15, 81377, Munich, Germany
    J Neurooncol 110:389-95. 2012
    ..Thus, [(18)F]FET-PET kinetics may provide valuable additional prognostic information for treatment decisions...
  24. doi request reprint New similarity search based glioma grading
    Katrin Haegler
    Department of Neuroradiology, Ludwig Maximilians University of Munich, Marchioninistrasse 15, 81377, Munich, Germany
    Neuroradiology 54:829-37. 2012
    ..Here, we tested the potential of a recently developed similarity search based method that integrates information of CE-T1w and perfusion maps for non-invasive MR-based glioma grading...
  25. doi request reprint FET-PET for malignant glioma treatment planning
    Maximilian Niyazi
    Department of Radiation Oncology, Ludwig Maximilians University Munich, Munchen, Germany
    Radiother Oncol 99:44-8. 2011
    ....
  26. doi request reprint Presence of pluripotent CD133+ cells correlates with malignancy of gliomas
    Niklas Thon
    Department of Neurosurgery, Hospital of the University of Munich, Marchioninistr 15, 81377 Munich, Germany
    Mol Cell Neurosci 43:51-9. 2010
    ..Since GBM frequently develops from low grade gliomas (WHO grade II) we assessed a possible qualitative or quantitative correlation of CD133(+) cells and glioma grade to get new insights in gliomagenesis...
  27. ncbi request reprint Vascular endothelial growth factor A contributes to glioma-induced migration of human marrow stromal cells (hMSC)
    Christian Schichor
    Department of Neurosurgery, Ludwig Maximilians University, Klinikum Grosshadern, Marchioninistr 15, 81377 Munich, Germany
    Exp Neurol 199:301-10. 2006
    ....
  28. pmc Serial O-(2-[(18)F]fluoroethyl)-L: -tyrosine PET for monitoring the effects of intracavitary radioimmunotherapy in patients with malignant glioma
    Gabriele Popperl
    Department of Nuclear Medicine, Klinikum Grosshadern, University of Munich, Marchioninistrasse 15, 81377 Munich, Germany
    Eur J Nucl Med Mol Imaging 33:792-800. 2006
    ....
  29. ncbi request reprint [Insulin therapy improves cardiac autonomic function in type 2 diabetic patients]
    Oliver Schnell
    3 Medizinische Abteilung KH München Schwabing und Institut für Diabetesforschung, Munchen
    Herz 29:519-23. 2004
    ..There is scintigraphic evidence that insulin improves cardiac autonomic innervation in diabetic patients. The aim of the study was to assess the effects of insulin therapy on parameters of cardiac reflex tests in type 2 diabetic patients...
  30. ncbi request reprint Insulin as a first-line therapy in type 2 diabetes: should the use of sulfonylureas be halted?
    Eberhard Standl
    Munich Diabetes Research Institute, Kölner Pl 1, D 80804 Munich, Germany
    Diabetes Care 31:S136-9. 2008
  31. ncbi request reprint Prokinetic therapy: what can be measured by gastric scintigraphy?
    Rainer Linke
    Department of Nuclear Medicine, University of Munich, Germany
    Nucl Med Commun 26:527-33. 2005
    ..To evaluate whether gastric scintigraphy with quantitative analysis of gastric peristalsis may be a useful tool for documenting the effects of prokinetic therapy...
  32. doi request reprint What should be the antihypertensive drug of choice in diabetic patients and should we avoid drugs that increase glucose levels? Pro and Cons
    Eberhard Standl
    Munich Diabetes Research Group e V, Munich Helmholtz Centre, Ingolstaedter Landstrasse 1, Munich Neuherberg, Germany
    Diabetes Metab Res Rev 28:60-6. 2012
    ..Awareness of these facts and highly individualized therapy seem to be the way forward...
  33. doi request reprint Near-infrared indocyanine green videoangiography (ICGVA) and intraoperative computed tomography (iCT): are they complementary or competitive imaging techniques in aneurysm surgery?
    Oliver Schnell
    Department of Neurosurgery, Klinikum der Ludwig Maximilians Universität München, Campus Grosshadern, Marchioninistrasse 15, 81377, Munich, Germany
    Acta Neurochir (Wien) 154:1861-8. 2012
    ....
  34. pmc Krüppel-like factor 8 (KLF8) is expressed in gliomas of different WHO grades and is essential for tumor cell proliferation
    Oliver Schnell
    Department of Neurosurgery, Klinikum der Ludwig Maximilians Universität München, Campus Grosshadern, Munich, Germany
    PLoS ONE 7:e30429. 2012
    ..Selective blocking of KLF8 might represent a novel anti-proliferative treatment strategy for malignant gliomas. Yet, its simultaneous expression in non-proliferating tissues could hamper this approach...
  35. ncbi request reprint The links between diabetes and cardiovascular disease
    Oliver Schnell
    Diabetes Research Institute, Munich, Germany
    J Interv Cardiol 18:413-6. 2005
    ..Preventive treatment strategies, which include multiple approaches, are required to overcome the burden of cardiovascular disease in diabetes and IGT...
  36. ncbi request reprint On the potential of acarbose to reduce cardiovascular disease
    Eberhard Standl
    Munich Diabetes Research Group e, V, at Helmholtz Centre, Ingolstaedter Landstrasse 1, 85764 Munich, Neuherberg, Germany
    Cardiovasc Diabetol 13:81. 2014
    ....
  37. pmc Imaging of integrin alpha(v)beta(3) expression in patients with malignant glioma by [18F] Galacto-RGD positron emission tomography
    Oliver Schnell
    Department of Neurosurgery, Klinikum Grosshadern, Ludwig Maximilians Universitat Munchen, Munich, Germany
    Neuro Oncol 11:861-70. 2009
    ..These data suggest that [(18)F] Galacto-RGD PET successfully identifies alpha(v)beta(3) expression in patients with GBM and might be a promising tool for planning and monitoring individualized cancer therapies targeting this integrin...
  38. doi request reprint 5-Aminolevulinic acid-induced protoporphyrin IX levels in tissue of human malignant brain tumors
    Ann Johansson
    Laser Forschungslabor, University Clinic Großhadern, Munich, Germany
    Photochem Photobiol 86:1373-8. 2010
    ..However, the feasibility of PDT for grade III brain tumors and for grade IV brain tumors displaying mainly necrotic tissue areas without solid tumor parts needs to be further investigated...
  39. pmc Expression of integrin alphavbeta3 in gliomas correlates with tumor grade and is not restricted to tumor vasculature
    Oliver Schnell
    Department of Neurosurgery, Klinikum Grosshadern, Ludwig Maximilians Universitat Munchen, Munich, Germany
    Brain Pathol 18:378-86. 2008
    ....
  40. ncbi request reprint Intratumoral homogeneity of MGMT promoter hypermethylation as demonstrated in serial stereotactic specimens from anaplastic astrocytomas and glioblastomas
    Eva M Grasbon-Frodl
    Center for Neuropathology and Prion Research, Ludwig Maximilians Universitat Munchen, Munich, Germany
    Int J Cancer 121:2458-64. 2007
    ..The methylation profile, as defined by MSP and sodium bisulfite sequencing, constitutes a homogeneous marker throughout malignant gliomas. The lack of correlation between MGMT status and MGMT protein expression needs further evaluation...
  41. ncbi request reprint Impaired glucose tolerance, diabetes, and cardiovascular disease
    Oliver Schnell
    University of Munich and Diabetes Research Institute, Germany
    Endocr Pract 12:16-9. 2006
    ..To analyze the association among impaired glucose tolerance (IGT), diabetes, and cardiovascular disease (CVD)...
  42. ncbi request reprint Deferoxamine improves coronary vascular responses to sympathetic stimulation in patients with type 1 diabetes mellitus
    Naoya Hattori
    Nuklearmedizinische Klinik und Poliklinik, Klinikum rechts der Isar, Technischen Universitat Munchen, Germany
    Eur J Nucl Med Mol Imaging 29:891-8. 2002
    ..Hydroxyl radicals may play a role in the pathogenesis of flow abnormalities in type 1 diabetes...
  43. ncbi request reprint An advanced approach for the assessment of gastric motor function in long-term type 1 diabetes mellitus with and without autonomic neuropathy
    Matthias Meier
    Hannover Medical School, Department of Nephrology, Germany
    Clin Auton Res 12:197-202. 2002
    ..Analyzing gastric motor function with dynamic scintigraphic techniques using condensed images is a promising clinical approach to further elucidate the mechanisms of impaired gastric motility in DM...
  44. ncbi request reprint Dysregulation of coronary microvascular reactivity in asymptomatic patients with type 2 diabetes mellitus
    Mitsuru Momose
    Nuklearmedizinische Klinik und Poliklinik der Technischen Universität München, Klinikum rechts der Isar, Ismaninger Strasse 22, 81675 Munich, Germany
    Eur J Nucl Med Mol Imaging 29:1675-9. 2002
    ..These data suggest a state of activation of endothelial-dependent vasodilation at baseline which appears to limit the flow response to stress conditions...
  45. ncbi request reprint HIS modelling and simulation based cost-benefit analysis of a telemedical system for closed-loop diabetes therapy
    Oliver J Bott
    Institute for Medical Informatics, Technical University of Braunschweig, Muehlenpfordtstr 23, D 38106 Braunschweig, Germany
    Int J Med Inform 76:S447-55. 2007
    ..This study aims at identifying and applying suitable methods for a cost-benefit analysis from the perspective of the payor for health services...
  46. doi request reprint The INCA system: a further step towards a telemedical artificial pancreas
    Enrique J Gomez
    Universidad Politecnica de Madrid, 28040 Madrid, Spain
    IEEE Trans Inf Technol Biomed 12:470-9. 2008
    ..The INCA system has been technically and clinically evaluated in two randomized and crossover clinical trials showing an improvement on glycaemic control of diabetic patients...
  47. ncbi request reprint Simulation based cost-benefit analysis of a telemedical system for closed-loop insulin pump therapy of diabetes
    Oliver J Bott
    Institute for Medical Informatics, Technical University of Braunschweig, Germany
    Stud Health Technol Inform 124:435-40. 2006
    ..Cost-benefit analyses of such systems are needed to decide on the introduction of telemedical systems such as the INCA system to routine care...
  48. ncbi request reprint [When will the artificial pancreas be available? (interview by Dr. med. Jochen Aumiller)]
    Oliver Schnell
    MMW Fortschr Med 149:16. 2007
  49. ncbi request reprint Endogenous ciliary neurotrophic factor protects GABAergic, but not cholinergic, septohippocampal neurons following fimbria-fornix transection
    Thomas Naumann
    Institute of Anatomy, University of Freiburg, Germany
    Brain Pathol 13:309-21. 2003
    ..In the septum, endogenous CNTF specifically supports lesioned GABAergic projection neurons, whereas LIF may play a similar role for the cholinergic counterparts...
  50. ncbi request reprint Positron emission tomography using [18F]Galacto-RGD identifies the level of integrin alpha(v)beta3 expression in man
    Ambros J Beer
    Department of Nuclear Medicine, Lehrstuhl II für organische Chemie, Technische Universitat Munchen, Germany
    Clin Cancer Res 12:3942-9. 2006
    ..We have developed [18F]Galacto-RGD, a highly alpha(v)beta3-selective tracer for positron emission tomography (PET). Here, we show, in man, that the intensity of [18F]Galacto-RGD uptake correlates with alpha(v)beta3 expression...