Research Topics
Genomes and GenesSpecies | Wilhelm H SchmittSummaryAffiliation: University of Heidelberg Country: Germany Publications
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Publications
Organ transplantation in the vasculitidesWilhelm H Schmitt
Vth Medical Clinic Nephrology, Endocrinology, University Clinic Mannheim, Faculty of Clinical Medicine of the University of Heidelberg, Germany
Curr Opin Rheumatol 15:22-8. 2003..This review summarizes the current knowledge on indications and contraindications for renal transplantation in AASV and discusses the impact of posttransplant immunosuppression on the course of the patients...
Clinical applications of antineutrophil cytoplasmic antibody testingWilhelm H Schmitt
Vth Medical Clinic Nephrology, Endocrinolgy, Rheumatolgy, University Clinic Mannheim, Faculty of Clinical Medicine of the University of Heidelberg, Mannheim, Germany
Curr Opin Rheumatol 16:9-17. 2004..This review summarizes the most recent developments in the field, identifies areas of uncertainty, and gives practical guidelines...
Treatment of refractory Wegener's granulomatosis with antithymocyte globulin (ATG): an open study in 15 patientsWilhelm H Schmitt
Fifth Department of Medicine, University Hospital Mannheim of the University of Heidelberg, Mannheim, Germany
Kidney Int 65:1440-8. 2004..Anecdotal data suggest that antithymocyte globulin (ATG) may be a treatment option for these patients. We now describe 15 patients treated with ATG for refractory Wegener's granulomatosis...
Newer insights into the aetiology and pathogenesis of myeloperoxidase associated autoimmunityWilhelm H Schmitt
Vth Medical Clinic, University Hospital Mannheim, Heidelberg University, Mannheim, Germany
Jpn J Infect Dis 57:S7-8. 2004..Finally, data derived from closely related autoantibodies against proteinase 3 (PR3) suggest anti-idiotypic antibodies induced by antisense transcripts as potential pathological agents...
Prolonged treatment of refractory Wegener's granulomatosis with 15-deoxyspergualin: an open study in seven patientsWilhelm H Schmitt
Fifth Medical Clinic, University Hospital Mannheim, Heidelberg University, Theodor Kutzer Ufer 1 3, D 68135 Mannheim, Germany
Nephrol Dial Transplant 20:1083-92. 2005..A 6 month course of the immunosuppressant 15-deoxyspergualin (DSG) has previously been employed successfully in these refractory cases. However, there are no reports on long-term treatment with DSG...
Persistent T-cell activation and clinical correlations in patients with ANCA-associated systemic vasculitisSmaragdi Marinaki
Fifth Department of Medicine, University Hospital Mannheim, University of Heidelberg, Theodor-Kutzer-Ufer 1-3, D-68135 Mannheim, Germany
Nephrol Dial Transplant 21:1825-32. 2006..These phenotypes are persistent and do not reflect disease activity. PTA predominantly occurs in patients with severe disease. This might explain the higher cumulative cyclophosphamide dose found in these patients...
Retinoid X receptor beta polymorphisms do not explain functional differences in vitamins D and A response in Antineutrophil cytoplasmic antibody associated vasculitis patientsAnna Isabelle Kälsch
Fifth Department of Medicine, University Hospital Mannheim, Faculty of Medicine Mannheim, University of Heidelberg, Heidelberg, Germany
Autoimmunity 42:467-74. 2009..Since the inhibition of TNFalpha was more effective in patients, vitamin D supplementation might be an additional therapeutical approach...
Use of highly sensitive C-reactive protein for followup of Wegener's granulomatosisAnna Isabelle Kälsch
Fifth Medical Department, University Medical Centre Mannheim, Medical Faculty of Mannheim of the University of Heidelberg, Theodor Kutzer Ufer 1 3, D 68187 Mannheim, Germany
J Rheumatol 37:2319-25. 2010..We evaluated whether during remission elevated highly sensitive CRP (hsCRP) precedes relapse as a marker of subclinical inflammation and thus might improve clinical assessment...
Proton pump inhibitors interfere with the immunosuppressive potency of mycophenolate mofetilMatthias Schaier
Department of Nephrology, University of Heidelberg, Heidelberg, Germany
Rheumatology (Oxford) 49:2061-7. 2010..Since PPIs are widely used, it is useful to clarify whether the total drug amount of MMF is available in patients undergoing PPI treatment...
Serial ANCA determinations for monitoring disease activity in patients with ANCA-associated vasculitis: systematic reviewRainer Birck
Fifth Department of Medicine, University Hospital Mannheim, Faculty of Clinical Medicine, University of Heidelberg, Mannheim, Germany
Am J Kidney Dis 47:15-23. 2006..To assess the diagnostic value of serial ANCA testing in the follow-up of patients with AASV, we conducted a systematic review of the available literature...
