U Schlötzer-Schrehardt

Summary

Affiliation: University of Erlangen-Nuremberg
Country: Germany

Publications

  1. ncbi request reprint Lymphatic vessels in vascularized human corneas: immunohistochemical investigation using LYVE-1 and podoplanin
    Claus Cursiefen
    Department of Ophthalmology and Nikolaus Fiebiger Zentrum for Molecular Medicine, University of Erlangen Nurnberg, Erlangen, Germany
    Invest Ophthalmol Vis Sci 43:2127-35. 2002
  2. ncbi request reprint Dose-related structural effects of photodynamic therapy on choroidal and retinal structures of human eyes
    Ursula Schlötzer-Schrehardt
    Department of Ophthalmology, University Erlangen Nurnberg, Schwabachanlage 6, 91054 Erlangen, Germany
    Graefes Arch Clin Exp Ophthalmol 240:748-57. 2002
  3. ncbi request reprint Expression and localization of FP and EP prostanoid receptor subtypes in human ocular tissues
    Ursula Schlötzer-Schrehardt
    Department of Ophthalmology, University of Erlangen Nurnberg, Schwabachanlage 6, D 91054 Erlangen, Germany
    Invest Ophthalmol Vis Sci 43:1475-87. 2002
  4. ncbi request reprint The Pathogenesis of floppy eyelid syndrome: involvement of matrix metalloproteinases in elastic fiber degradation
    Ursula Schlötzer-Schrehardt
    Department of Ophthalmology, University of Erlangen Nurnberg, Erlangen, Germany
    Ophthalmology 112:694-704. 2005
  5. ncbi request reprint Mitochondria-rich epithelioid leiomyoma of the ciliary body
    Ursula Schlötzer-Schrehardt
    Department of Ophthalmology, University Erlangen Nurnberg, Schwabachanlage 6, D 91054 Erlangen, Germany
    Arch Ophthalmol 120:77-82. 2002
  6. ncbi request reprint [Functional significance of adenosine receptors in the eye and their dysregulation in pseudoexfoliation syndrome]
    U Schlötzer-Schrehardt
    Augenklinik der Friedrich Alexander Universität Erlangen Nürnberg
    Ophthalmologe 102:1074-80, 1082. 2005
  7. ncbi request reprint Selective upregulation of the A3 adenosine receptor in eyes with pseudoexfoliation syndrome and glaucoma
    Ursula Schlötzer-Schrehardt
    Department of Ophthalmology, University of Erlangen Nurnberg, Germany
    Invest Ophthalmol Vis Sci 46:2023-34. 2005
  8. ncbi request reprint Multifocal corneal argyrosis after an explosion injury
    U Schlötzer-Schrehardt
    Department of Ophthalmology, University Nürnberg, Erlangen, Germany
    Cornea 20:553-7. 2001
  9. ncbi request reprint Energy-filtering transmission electron microscopy (EFTEM) in the elemental analysis of pseudoexfoliative material
    U Schlötzer-Schrehardt
    Department of Ophthalmology, University of Erlangen Nurnberg, Erlangen, Germany
    Curr Eye Res 22:154-62. 2001
  10. doi request reprint [Oxidative stress and pseudoexfoliation glaucoma]
    U Schlötzer-Schrehardt
    Augenklinik, Universitat Erlangen Nurnberg
    Klin Monbl Augenheilkd 227:108-13. 2010

Collaborators

Detail Information

Publications61

  1. ncbi request reprint Lymphatic vessels in vascularized human corneas: immunohistochemical investigation using LYVE-1 and podoplanin
    Claus Cursiefen
    Department of Ophthalmology and Nikolaus Fiebiger Zentrum for Molecular Medicine, University of Erlangen Nurnberg, Erlangen, Germany
    Invest Ophthalmol Vis Sci 43:2127-35. 2002
    ..To determine whether lymphatic vessels exist in vascularized human corneas, by using immunohistochemistry with novel markers for lymphatic endothelium...
  2. ncbi request reprint Dose-related structural effects of photodynamic therapy on choroidal and retinal structures of human eyes
    Ursula Schlötzer-Schrehardt
    Department of Ophthalmology, University Erlangen Nurnberg, Schwabachanlage 6, 91054 Erlangen, Germany
    Graefes Arch Clin Exp Ophthalmol 240:748-57. 2002
    ..To determine the effects of photodynamic therapy (PDT) on choroidal and retinal structures of human eyes...
  3. ncbi request reprint Expression and localization of FP and EP prostanoid receptor subtypes in human ocular tissues
    Ursula Schlötzer-Schrehardt
    Department of Ophthalmology, University of Erlangen Nurnberg, Schwabachanlage 6, D 91054 Erlangen, Germany
    Invest Ophthalmol Vis Sci 43:1475-87. 2002
    ..To determine the expression and precise cellular and subcellular localization of the EP prostanoid receptor subtypes EP(1) through EP(4) and the FP receptor in normal human ocular tissues on the protein and mRNA levels...
  4. ncbi request reprint The Pathogenesis of floppy eyelid syndrome: involvement of matrix metalloproteinases in elastic fiber degradation
    Ursula Schlötzer-Schrehardt
    Department of Ophthalmology, University of Erlangen Nurnberg, Erlangen, Germany
    Ophthalmology 112:694-704. 2005
    ....
  5. ncbi request reprint Mitochondria-rich epithelioid leiomyoma of the ciliary body
    Ursula Schlötzer-Schrehardt
    Department of Ophthalmology, University Erlangen Nurnberg, Schwabachanlage 6, D 91054 Erlangen, Germany
    Arch Ophthalmol 120:77-82. 2002
  6. ncbi request reprint [Functional significance of adenosine receptors in the eye and their dysregulation in pseudoexfoliation syndrome]
    U Schlötzer-Schrehardt
    Augenklinik der Friedrich Alexander Universität Erlangen Nürnberg
    Ophthalmologe 102:1074-80, 1082. 2005
    ..We investigated the expression of the receptor isoforms in eyes with PEX syndrome, which is associated with anterior chamber hypoxia and elevated intraocular pressure...
  7. ncbi request reprint Selective upregulation of the A3 adenosine receptor in eyes with pseudoexfoliation syndrome and glaucoma
    Ursula Schlötzer-Schrehardt
    Department of Ophthalmology, University of Erlangen Nurnberg, Germany
    Invest Ophthalmol Vis Sci 46:2023-34. 2005
    ..In the current study, the role of the adenosine system in the pathophysiology of pseudoexfoliation (PEX) syndrome, which is typically associated with anterior chamber hypoxia and elevated intraocular pressure, was examined...
  8. ncbi request reprint Multifocal corneal argyrosis after an explosion injury
    U Schlötzer-Schrehardt
    Department of Ophthalmology, University Nürnberg, Erlangen, Germany
    Cornea 20:553-7. 2001
    ..To document the clinical and histopathologic corneal features of a patient who developed multifocal corneal argyrosis after a chemical explosion injury with unusual involvement of the corneal stroma and keratocytes...
  9. ncbi request reprint Energy-filtering transmission electron microscopy (EFTEM) in the elemental analysis of pseudoexfoliative material
    U Schlötzer-Schrehardt
    Department of Ophthalmology, University of Erlangen Nurnberg, Erlangen, Germany
    Curr Eye Res 22:154-62. 2001
    ..To obtain more information on the basic nature of the pathological matrix product accumulating in pseudoexfoliation (PEX) syndrome by analyzing its elemental composition at the subcellular level...
  10. doi request reprint [Oxidative stress and pseudoexfoliation glaucoma]
    U Schlötzer-Schrehardt
    Augenklinik, Universitat Erlangen Nurnberg
    Klin Monbl Augenheilkd 227:108-13. 2010
    ..Oxidative stress, therefore, appears to represent a modifiable risk factor in the management of patients with PEX syndrome/glaucoma...
  11. ncbi request reprint Matrix metalloproteinases and their inhibitors in aqueous humor of patients with pseudoexfoliation syndrome/glaucoma and primary open-angle glaucoma
    Ursula Schlötzer-Schrehardt
    Department of Ophthalmology, University of Erlangen Nurnberg, Erlangen, Germany
    Invest Ophthalmol Vis Sci 44:1117-25. 2003
    ....
  12. ncbi request reprint Role of transforming growth factor-beta1 and its latent form binding protein in pseudoexfoliation syndrome
    U Schlötzer-Schrehardt
    Department of Ophthalmology, University of Erlangen Nurnberg, Erlangen, Germany
    Exp Eye Res 73:765-80. 2001
    ..Future therapeutic strategies might focus on TGF-beta1 antagonistic approaches...
  13. ncbi request reprint Adenoma of the nonpigmented ciliary epithelium mimicking a malignant melanoma of the iris
    C Cursiefen
    Department of Ophthalmology, University Eye Hospital, Friedrich Alexander University Erlangen Nurnberg, Germany
    Arch Ophthalmol 117:113-6. 1999
    ..Postoperative visual acuity was 20/40 OD after 6 weeks. An adenoma of the nonpigmented ciliary epithelium may mimic an amelanotic malignant melanoma of the iris and should be considered in its differential diagnosis...
  14. ncbi request reprint Elastic fiber proteins in the glomerular mesangium in vivo and in cell culture
    R B Sterzel
    Medizinische Klinik IV and Augenklinik mit Poliklinik, Universitat Erlangen Nurnberg, Erlangen, Germany
    Kidney Int 58:1588-602. 2000
    ..The aim of this study was to clarify the exact glomerular localization, composition, and cellular production of these proteins...
  15. ncbi request reprint Ocular findings in ichthyosis follicularis, atrichia, and photophobia syndrome
    C Cursiefen
    Department of Ophthalmology, Friedrich Alexander University Erlangen Nurnberg, Erlangen, Germany
    Arch Ophthalmol 117:681-4. 1999
    ..A defective tear film, recurrent atopic keratoconjunctival inflammations, or a primary anomaly of corneal epithelial adhesion are potential causes for the corneal defects. Photophobia is most likely due to corneal abnormalities...
  16. doi request reprint [New pathogenetic insights into pseudoexfoliation syndrome/glaucoma. Therapeutically relevant?]
    U Schlötzer-Schrehardt
    Augenklinik, Universitatsklinikum Erlangen, Friedrich Alexander Universitat Erlangen Nurnberg, Schwabachanlage 6, 91054 Erlangen
    Ophthalmologe 109:944-51. 2012
    ..The findings may have direct consequences for the clinical management of PEX patients underlining the need for an exact diagnosis, a strict IOP-reducing therapy and a close and regular follow-up...
  17. ncbi request reprint Expression of cyclooxygenase-1 and -2 in normal and glaucomatous human eyes
    C Maihofner
    Department of Experimental and Clinical Pharmacology and Toxicology, University of Erlangen Nurnberg, Germany
    Invest Ophthalmol Vis Sci 42:2616-24. 2001
    ....
  18. ncbi request reprint Pseudoexfoliation syndrome in eyes with ischemic central retinal vein occlusion. A histopathologic and electron microscopic study
    C Cursiefen
    Department of Ophthalmology, University Erlangen Nurnberg, Schwabachanlage 6, D 91054 Erlangen, Germany
    Acta Ophthalmol Scand 79:476-8. 2001
    ..These deposits could explain an association of CRVO and PEX...
  19. ncbi request reprint Corneal stromal calcification after topical steroid-phosphate therapy
    U Schlötzer-Schrehardt
    Department of Ophthalmology, University Erlangen Nurnberg, Germany
    Arch Ophthalmol 117:1414-8. 1999
    ....
  20. ncbi request reprint Q-switched erbium:YAG laser corneal trephination: thermal damage in corneal stroma and cut regularity of nonmechanical Q-switched erbium:YAG laser corneal trephination for penetrating keratoplasty
    M Stojkovic
    Department of Ophthalmology, Friedrich Alexander University University of Erlangen Nurnberg, Schwabachanlage 6, D 91054 Erlangen, Germany
    Cornea 23:50-60. 2004
    ..To assess stromal thermal damage and cut regularity induced by nonmechanical Q-switched Er:YAG laser corneal trephination for penetrating keratoplasty...
  21. ncbi request reprint Characterization of extracellular matrix components in the limbal epithelial stem cell compartment
    U Schlötzer-Schrehardt
    Department of Ophthalmology, University of Erlangen Nurnberg, Schwabachanlage 6, D 91054 Erlangen, Germany
    Exp Eye Res 85:845-60. 2007
    ..Identification of specific niche parameters might not only help to understand limbal stem cell regulation, but also to improve their selective enrichment and in vitro expansion for therapeutic strategies...
  22. pmc Effect of latanoprost and timolol on the histopathology of the human conjunctiva
    N Terai
    Department of Ophthalmology, Carl Gustav Carus University Hospital, Fetscherstrasse 74, Dresden, Germany
    Br J Ophthalmol 93:219-24. 2009
    ....
  23. ncbi request reprint "Masked" pseudoexfoliation syndrome in unoperated eyes with circular posterior synechiae: clinical-electron microscopic correlation
    C Y Mardin
    Department of Ophthalmology, University of Erlangen Nurnberg, Erlangen, Germany
    Arch Ophthalmol 119:1500-3. 2001
    ..To investigate the prevalence of "masked" pseudoexfoliation (PEX) syndrome in eyes with circular posterior synechiae receiving antiglaucomatous therapy with miotics...
  24. ncbi request reprint Persisting retinal ganglion cell axons in blind atrophic human eyes
    C Cursiefen
    Department of Ophthalmology, University of Erlangen Nurnberg, Schwabachanlage 6, 91054 Erlangen, Germany
    Graefes Arch Clin Exp Ophthalmol 239:158-64. 2001
    ..To evaluate enucleated blind atrophic human eyes for the persistence of retinal ganglion cell axons. This might be of relevance for contact to an electronic prosthesis in the future...
  25. ncbi request reprint Analysis of aqueous humour proteins of eyes with and without pseudoexfoliation syndrome
    J Berlau
    Department of Ophthalmology, University of Rostock, Germany
    Graefes Arch Clin Exp Ophthalmol 239:743-6. 2001
    ..Furthermore, we could not detect any characteristic difference in protein band sizes of the two groups after SDS PAGE. However, we were able to show the presence of amyloid exclusively in aqueous humour of PEX patients...
  26. ncbi request reprint Merkel cell carcinoma: clinicopathologic correlation, management, and follow-up in five patients
    F Colombo
    Department of Ophthalmology and Eye Hospital, University Erlangen Nurnberg, Erlangen, Germany
    Ophthal Plast Reconstr Surg 16:453-8. 2000
    ..To review the clinicopathologic features, management and follow-up in five patients with periocular Merkel cell carcinoma (MCC)...
  27. ncbi request reprint Immunohistochemical classification of primary and recurrent macular corneal dystrophy in Germany: subclassification of immunophenotype I A using a novel keratan sulfate antibody
    C Cursiefen
    Department of Ophthalmology and University Eye Hospital, University of Erlangen Nurnberg, Erlangen, Germany
    Exp Eye Res 73:593-600. 2001
    ..The mAb 3D12/H7 allows a further subclassification of immunophenotype I A into type I A1 and 2. This points to a broader spectrum of MCD immunophenotypes and indirectly to a broader corneal proteoglycan pathology in MCD...
  28. pmc Pericyte recruitment in human corneal angiogenesis: an ultrastructural study with clinicopathological correlation
    C Cursiefen
    Department of Ophthalmology, University of Erlangen Nurnberg, Erlangen, Germany
    Br J Ophthalmol 87:101-6. 2003
    ..This study analyses whether, and if so when, pathological vessels in human corneal neovascularisation (CN) acquire pericyte coverage. This can be of importance for future angioregressive therapeutic strategies...
  29. ncbi request reprint Orbital lymphangioma with positive immunohistochemistry of lymphatic endothelial markers (vascular endothelial growth factor receptor 3 and podoplanin)
    C Cursiefen
    Department of Ophthalmology, Friedrich Alexander University Erlangen Nuremberg, Erlangen, Germany
    Graefes Arch Clin Exp Ophthalmol 239:628-32. 2001
    ..Existence of true orbital lymphangiomas has been questioned in recent years. Therefore an orbital lymphangioma was analyzed with two new specific markers of lymphatic endothelium...
  30. ncbi request reprint Early conjunctival changes following treatment with metipranolol and preservatives are not reversible with dexamethasone
    H Mietz
    Department of Ophthalmology, University of Cologne, Germany
    Graefes Arch Clin Exp Ophthalmol 235:452-9. 1997
    ..We sought to determine whether, after short-term use of metipranolol with preservatives, subsequent application of steroids or metipranolol without preservatives affects these conjunctival changes...
  31. ncbi request reprint Ocular findings in Fryns syndrome
    C Cursiefen
    Department of Ophthalmology, University Eye Hospital, Friedrich Alexander University Erlangen Nurnberg, Germany
    Acta Ophthalmol Scand 78:710-3. 2000
    ..The prevalence is about 0.7 per 10,000 births. Reported ocular features include microphthalmus, "cloudy cornea", irregularities of Bowman's layer, thickened posterior lens capsule and retinal dysplasia...
  32. ncbi request reprint Impaired cytoprotective mechanisms in eyes with pseudoexfoliation syndrome/glaucoma
    Matthias Zenkel
    Department of Ophthalmology, University of Erlangen Nurnberg, Erlangen, Germany
    Invest Ophthalmol Vis Sci 48:5558-66. 2007
    ..The expression of stress-related genes in eyes from patients with and without PEX syndrome/glaucoma was investigated to determine whether PEX syndrome is associated with an altered cellular stress response...
  33. doi request reprint The prostaglandin transporter OATP2A1 is expressed in human ocular tissues and transports the antiglaucoma prostanoid latanoprost
    Michaela E Kraft
    Institute of Experimental and Clinical Pharmacology and Toxicology, Friedrich Alexander University of Erlangen Nuremberg, Erlangen, Germany
    Invest Ophthalmol Vis Sci 51:2504-11. 2010
    ....
  34. doi request reprint Intraocular lymphangiogenesis in malignant melanomas of the ciliary body with extraocular extension
    Ludwig M Heindl
    Department of Ophthalmology and Eye Hospital, Ophthalmic Pathology Laboratory, Friedrich Alexander University Erlangen Nurnberg, Erlangen, Germany
    Invest Ophthalmol Vis Sci 50:1988-95. 2009
    ....
  35. pmc Corneal limbal microenvironment can induce transdifferentiation of hair follicle stem cells into corneal epithelial-like cells
    Ewa Anna Blazejewska
    Department of Ophthalmology, University of Erlangen Nuremberg, Germany
    Stem Cells 27:642-52. 2009
    ..Therefore, the HF may be an easily accessible alternative therapeutic source of autologous adult stem cells for replacement of the corneal epithelium and restoration of visual function in patients with ocular surface disorders...
  36. pmc Proinflammatory cytokines are involved in the initiation of the abnormal matrix process in pseudoexfoliation syndrome/glaucoma
    Matthias Zenkel
    Department of Ophthalmology, University of Erlangen Nurnberg, Schwabachanlage 6, D 91054 Erlangen, Germany
    Am J Pathol 176:2868-79. 2010
    ..These findings support a role for a stress-induced, spatially, and temporally restricted subclinical inflammation in the onset of the fibrotic matrix process characteristic of PEX syndrome/glaucoma...
  37. ncbi request reprint Homocysteine in tear fluid of patients with pseudoexfoliation glaucoma
    Johannes B Roedl
    Department of Ophthalmology and University Eye Hospital, Germany
    J Glaucoma 16:234-9. 2007
    ..To evaluate homocysteine (Hcy) concentrations in tear fluid and plasma and their association with B-vitamin levels in patients with pseudoexfoliation glaucoma (PEXG)...
  38. ncbi request reprint Clusterin deficiency in eyes with pseudoexfoliation syndrome may be implicated in the aggregation and deposition of pseudoexfoliative material
    Matthias Zenkel
    Department of Ophthalmology, University of Erlangen Nurnberg, Erlangen, Germany
    Invest Ophthalmol Vis Sci 47:1982-90. 2006
    ....
  39. ncbi request reprint Inverse mushroom-shaped nonmechanical penetrating keratoplasty using a femtosecond laser
    Berthold Seitz
    Department of Ophthalmology, University of Erlangen Nurnberg, Schwabachanlage 6, D 91054 Erlangen, Germany
    Am J Ophthalmol 139:941-4. 2005
    ..To demonstrate the feasibility of an inverse mushroom-shaped nonmechanical corneal trephination using a femtosecond laser in a noncontact manner...
  40. ncbi request reprint Elevated homocysteine levels in aqueous humor of patients with pseudoexfoliation glaucoma
    Stefan Bleich
    Dept of Psychiatry and Psychotherapy, Friedrich Alexander University of Erlangen Nuremberg, Schwabachanlage 6, 91054 Erlangen, Germany
    Am J Ophthalmol 138:162-4. 2004
    ..To determine total homocysteine levels in aqueous humor of pseudoexfoliation open-angle glaucoma patients...
  41. ncbi request reprint Collagen IV is essential for basement membrane stability but dispensable for initiation of its assembly during early development
    Ernst Poschl
    Department of Experimental Medicine I, University Erlangen Nurnberg, 91054 Erlangen, Germany
    Development 131:1619-28. 2004
    ....
  42. ncbi request reprint Nonmechanical posterior lamellar keratoplasty using the femtosecond laser (femto-plak) for corneal endothelial decompensation
    Berthold Seitz
    Department of Ophthalmology, University of Erlangen Nurnberg, Erlangen, Germany
    Am J Ophthalmol 136:769-72. 2003
    ..To assess the potential of a short pulsed laser to cut a posterior graft and bed for posterior lamellar keratoplasty (PLAK)...
  43. ncbi request reprint The C5 domain of Col6A3 is cleaved off from the Col6 fibrils immediately after secretion
    T Aigner
    Cartilage Research Group, Department of Pathology, University of Erlangen Nurnberg, Erlangen, Federal Republic of Germany
    Biochem Biophys Res Commun 290:743-8. 2002
    ....
  44. doi request reprint Increased homocysteine levels in tear fluid of patients with primary open-angle glaucoma
    J B Roedl
    Department of Ophthalmology, University Eye Hospital, Erlangen Nuremberg, Germany
    Ophthalmic Res 40:249-56. 2008
    ..We assessed homocysteine (Hcy) levels in tear fluid and plasma of patients with primary open-angle glaucoma (POAG). We determined the association between Hcy levels, dry eye syndrome and B vitamin status...
  45. doi request reprint [Limbal stem cells and their niche: implications for bioengineered tissue constructs]
    J Menzel-Severing
    Augenklinik, Universitatsklinikum Erlangen, Germany
    Klin Monbl Augenheilkd 229:1191-7. 2012
    ..In addition, a summary is given of novel concepts which aim at integrating putative niche factors into the stem cell carriers to replicate the stem cell niche...
  46. doi request reprint [Nodular fasciitis of the eyelid and anterior orbit in children: case report and review of the literature]
    R W Damasceno
    Augenklinik mit Poliklinik, Universitat Erlangen Nurnberg, Schwabachanlage 6, 91054 Erlangen
    Ophthalmologe 106:829-31. 2009
    ..Five years after surgery, there is no evidence of local recurrence, and the result is aesthetically satisfactory...
  47. ncbi request reprint [Postoperative opacification of 12 hydrogel foldable lenses (Hydroview(R))]
    M J Groh
    Augenklinik mit Poliklinik der Universität Erlangen Nürnberg, Schwabachanlage 6, 91054 Erlangen
    Klin Monbl Augenheilkd 218:645-8. 2001
    ..To evaluate postoperative lens opacifications in foldable hydrophilic intraocular lenses...
  48. doi request reprint Histologic analysis of descemet stripping in posterior lamellar keratoplasty
    Ludwig M Heindl
    Department of Ophthalmology and University Eye Hospital, University Erlangen Nurnberg, Schwabachanlage 6, 91054 Erlangen, Germany
    Arch Ophthalmol 126:461-4. 2008
    ..To investigate how precise Descemet stripping works in posterior lamellar keratoplasty (Descemet stripping automated endothelial keratoplasty [DSAEK]) for the treatment of corneal endothelial disorders...
  49. doi request reprint Exploring functional candidate genes for genetic association in german patients with pseudoexfoliation syndrome and pseudoexfoliation glaucoma
    Mandy Krumbiegel
    Institute of Human Genetics, University of Erlangen Nuremberg, Erlangen, Germany
    Invest Ophthalmol Vis Sci 50:2796-801. 2009
    ..This study was focused on six functional candidate genes involved in PEX material deposition and the analysis of their potential association with PEX syndrome and PEX glaucoma (PEXG)...
  50. doi request reprint Preservation of the limbal stem cell phenotype by appropriate culture techniques
    Ewa Anna Meyer-Blazejewska
    Department of Ophthalmology, Friedrich Alexander University of Erlangen Nurnberg, Erlangen, Germany
    Invest Ophthalmol Vis Sci 51:765-74. 2010
    ....
  51. doi request reprint Carcinoma-associated retinopathy-an electrophysiological and immunohistochemical correlation
    Barbara Link
    Department of Ophthalmology, University of Erlangen Nuernberg, Erlangen, Germany
    Retina 29:69-72. 2009
    ..To correlate the clinical, electrophysiological, and immunohistochemical findings in patients suffering from carcinoma-associated retinopathy...
  52. pmc Genotype-correlated expression of lysyl oxidase-like 1 in ocular tissues of patients with pseudoexfoliation syndrome/glaucoma and normal patients
    Ursula Schlötzer-Schrehardt
    Department of Ophthalmology, University of Erlangen Nurnberg, Erlangen, Germany
    Am J Pathol 173:1724-35. 2008
    ..Alterations of LOXL1 activation, processing, and/or substrate specificity may contribute to the abnormal aggregation of elastic fiber components into characteristic PEX fibrils...
  53. doi request reprint Molecular pathology of pseudoexfoliation syndrome/glaucoma--new insights from LOXL1 gene associations
    Ursula Schlötzer-Schrehardt
    Department of Ophthalmology, University of Erlangen Nurnberg, Erlangen, Germany
    Exp Eye Res 88:776-85. 2009
    ....
  54. doi request reprint Safety profile of topical VEGF neutralization at the cornea
    Felix Bock
    Department of Ophthalmology, University of Erlangen Nurnberg, Erlangen, Germany
    Invest Ophthalmol Vis Sci 50:2095-102. 2009
    ..Bevacizumab eyedrops inhibit corneal neovascularization. The purpose of this study was to analyze the safety profile of VEGF-A neutralization at the ocular surface...
  55. doi request reprint Borrelia-associated crystalline keratopathy with intracorneal detection of Borrelia garinii by electron microscopy and polymerase chain reaction
    Tina Dietrich
    Department of Ophthalmology, Immunology and Hygiene, University Erlangen Nurnberg, Erlangen, Germany
    Cornea 27:498-500. 2008
    ..First report of a patient with Borrelia-associated crystalline keratopathy with intracorneal evidence of Borrelia garinii by polymerase chain reaction (PCR) and electron microscopy (EM)...
  56. doi request reprint Association of LOXL1 common sequence variants in German and Italian patients with pseudoexfoliation syndrome and pseudoexfoliation glaucoma
    Francesca Pasutto
    Institute of Human Genetics, Friedrich Alexander University Erlangen Nuremberg, Erlangen, Germany
    Invest Ophthalmol Vis Sci 49:1459-63. 2008
    ..In this study, the genetic association of these variants was investigated in patients with PEX or PEXG of German and Italian descent...
  57. ncbi request reprint Immunohistochemical identification of kynurenine aminotransferases in corpora amylacea in the human retina and optic nerve
    Robert Rejdak
    Friedrich Alexander University of Erlangen Nuremberg, Department of Ophthalmology, Schwabachanlage 6, D 91054 Erlangen, Germany
    Folia Neuropathol 45:66-71. 2007
    ..This study examines KAT I and II immunoreactivity in CAm in the human retina and optic nerve...
  58. ncbi request reprint Heterologous expression of wildtype and mutant myocilin in High Five insect cells shows comparable effects to cultivated trabecular meshwork cells
    Sevinc Oezbey
    University Hospital Erlangen, Institute of Human Genetics, Schwabachanlage 10, 91054, Erlangen, Germany
    Biomol Eng 24:313-7. 2007
    ..A direct attachment of ribosomes to these growing vesicles preceding the cell death was observed by electron microscopy. Our observations indicate that this system is suitable to trace the intracellular effects of MYOC mutants...
  59. ncbi request reprint Ucma, a novel secreted cartilage-specific protein with implications in osteogenesis
    Cordula Surmann-Schmitt
    Department of Experimental Medicine I, Nikolaus Fiebiger Center of Molecular Medicine, University of Erlangen Nuremberg, 91054 Erlangen, Germany
    J Biol Chem 283:7082-93. 2008
    ..These findings suggest that Ucma may be involved in the negative control of osteogenic differentiation of osteochondrogenic precursor cells in peripheral zones of fetal cartilage and at the cartilage-bone interface...
  60. ncbi request reprint Histopathology of corneal changes in lecithin-cholesterol acyltransferase deficiency
    Arne Viestenz
    Department of Ophthalmology, University Eye Hospital, University of Erlangen Nurnberg, Erlangen, Germany
    Cornea 21:834-7. 2002
    ..Lecithin-cholesterol acyltransferase (LCAT) deficiency is a rare entity. This dyslipoproteinemia may lead to corneal opacity, renal failure, and arteriosclerosis...
  61. ncbi request reprint Pseudoexfoliation syndrome: pathological manifestations of relevance to intraocular surgery
    R Max Conway
    Department of Ophthalmology and Eye Hospital, University of Erlangen Nurnberg, Erlangen, Germany
    Clin Experiment Ophthalmol 32:199-210. 2004
    ..In this short review, current reports relating to PEX pathological changes of practical interest to the intraocular surgeon are summarized...