Research Topics
| S SchipplingSummaryAffiliation: University of Hamburg Country: Germany Publications
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Detail Information
Publications
Spotlight on anti-CD25: daclizumab in MSDr Sven Schippling
Neurologische Klinik und Poliklinik, Universitatsklinikum Hamburg Eppendorf, Martinistr 52, 20246 Hamburg, Germany
Int MS J 15:94-8. 2008..Safety and efficacy data from the preliminary clinical exploration as well as findings about the mechanism of action of anti-CD25 treatment are reviewed here...
Contrasting disease patterns in seropositive and seronegative neuromyelitis optica: A multicentre study of 175 patientsSven Jarius
Neurocure, Charite University Medicine Berlin, Berlin, Germany
J Neuroinflammation 9:14. 2012..However, little is known so far about the clinical impact of AQP4-Ab seropositivity...
[Stem cell therapy in multiple sclerosis: a clinical update]S Schippling
Zentrum für Molekulare Neurobiologie, Institut für Neuroimmunologie und Klinische Multiple Sklerose Forschung INIMS, Falkenried 3, 20246, Hamburg, Deutschland
Z Rheumatol 68:214-5, 217-9. 2009..Although transplant related mortality has dropped to 1%, mortality combined with concerns about long-term safety remain critical issues in a primarily non-life-threatening disease like MS...
Stem cell transplantation in multiple sclerosisSven Schippling
Institute of Neuroimmunology and Multiple Sclerosis Research INiMS, Center of Molecular Neurobiology, Falkenried 3, 20246 Hamburg, Germany
J Neurol 255:43-7. 2008....
Quantitative T2' imaging in patients with clinically isolated syndromeL Y Reitz
Department of Neurology, Institute for Neuroimmunology and Clinical Multiple Sclerosis Research inims, University Medical Center, Hamburg, DE, Germany
Acta Neurol Scand 126:357-63. 2012..We aimed to explore the presence and extent of T2' changes in patients with a clinically isolated syndrome (CIS) and a possible association of T2' with conventional magnetic resonance imaging and clinical outcomes...
Early anisotropy changes in the corpus callosum of patients with optic neuritisM Bester
Department of Neuroradiology, University Medical Center Hamburg Eppendorf, Hamburg, Germany
Neuroradiology 50:549-57. 2008..In this prospective study we aimed to determine whether diffusion tensor imaging (DTI) could quantify structural changes in patients with early MS...
[Diagnosis and heterogeneity of MS in MRI]B Holst
Klinik und Poliklinik für neuroradiologische Diagnostik und Intervention, Universitatsklinikum Hamburg Eppendorf, Martinistrasse 52, Hamburg
Rofo 180:112-9. 2008..The previous challenge with respect to MRI was to support the diagnosis of MS via MRI criteria. A future problem will be the heterogeneity and classification of subgroups. This article gives an overview of both problems...
Amyloid-beta is an antioxidant for lipoproteins in cerebrospinal fluid and plasmaA Kontush
Medical Clinic, University Hospital Eppendorf, Hamburg, Germany
Free Radic Biol Med 30:119-28. 2001..These data suggest that Abeta(1-40) may act as a physiological antioxidant in CSF and plasma lipoproteins, functioning by chelating transition metal ions...
Inhibitory and facilitatory connectivity from ventral premotor to primary motor cortex in healthy humans at rest--a bifocal TMS studyT Baumer
Department of Neurology, University Medical Center Hamburg Eppendorf, Hamburg, Germany
Clin Neurophysiol 120:1724-31. 2009..In macaques, intracortical electrical stimulation of ventral premotor cortex (PMv) can modulate ipsilateral primary motor cortex (M1) excitability at short interstimulus intervals (ISIs)...
Plasma ubiquinol-10 as a marker for disease: is the assay worthwhile?A Kontush
Medizinische Klinik, Universitatskrankenhaus Eppendorf, Hamburg, Germany
Biofactors 9:225-9. 1999..These data suggest that the level of ubiquinol-10 in human plasma may serve as a marker for liver dysfunction, reflecting its diminished reduction by the liver rather than increased consumption by oxidants...
Accuracy of diagnostic tests in multiple sclerosis--a systematic reviewN Schäffler
Institute of Neuroimmunology and Clinical MS Research, University Medical Center Hamburg Eppendorf, Hamburg, Germany
Acta Neurol Scand 124:151-64. 2011..However, the value of a very early diagnosis stays questionable as patients' benefit of new diagnostic criteria has never been addressed...
T2' imaging indicates decreased tissue metabolism in frontal white matter of MS patientsB Holst
Department of Neuroradiology, University Medical Center Hamburg Eppendorf, Hamburg, Germany
Mult Scler 15:701-7. 2009..We hypothesized that T2' imaging is feasible in routine use and reveals differences between MS patients and healthy subjects...
Sensorimotor integration is abnormal in asymptomatic Parkin mutation carriers: a TMS studyT Baumer
Department of Neurology, University of Hamburg, Martinistrasse 52, 20246 Hamburg, Germany
Neurology 69:1976-81. 2007....
