H U Schildhaus

Summary

Affiliation: University of Bonn
Country: Germany

Publications

  1. pmc The Merendino procedure following preoperative imatinib mesylate for locally advanced gastrointestinal stromal tumor of the esophagogastric junction
    Wilko I Staiger
    Div, Surgical Oncology and Thoracic Surgery, Department of Surgery, University Hospital Mannheim, Medical Faculty Mannheim, University of Heidelberg, Germany
    World J Surg Oncol 6:37. 2008
  2. pmc qPCR in gastrointestinal stromal tumors: Evaluation of reference genes and expression analysis of KIT and the alternative receptor tyrosine kinases FLT3, CSF1-R, PDGFRB, MET and AXL
    Jana Fassunke
    Department of Pathology, University of Bonn Medical Center, Bonn, Germany
    BMC Mol Biol 11:100. 2010
  3. pmc Pitfalls in mutational testing and reporting of common KIT and PDGFRA mutations in gastrointestinal stromal tumors
    Sabine Merkelbach-Bruse
    Department of Pathology, University of Bonn Medical School, Sigmund Freud Str, 25 D 53127 Bonn, Germany
    BMC Med Genet 11:106. 2010
  4. doi request reprint [Inflammatory fibroid polyp: from Vanek's "submucosal granuloma" to the concept of submucosal mesenchymal neoplasia]
    H U Schildhaus
    Institut fur Pathologie, Universitatsklinikum Bonn, Sigmund Freud Str 25, 53127, Bonn, Deutschland
    Pathologe 31:109-14. 2010
  5. doi request reprint [Malignant mixed Müllerian tumor of the urinary bladder]
    H U Schildhaus
    Institut fur Pathologie, Universitatsklinikum Bonn, Sigmund Freud Strasse 25, 53127, Bonn
    Pathologe 29:375-7. 2008
  6. doi request reprint [Inflammatory fibroid polyps are true neoplasms with PDGFRA mutations]
    H U Schildhaus
    Institut fur Pathologie, Universitatsklinikum Bonn, Sigmund Freud Str 25, 53127 Bonn
    Pathologe 30:117-20. 2009
  7. doi request reprint [Pathology and molecular biology of gastrointestinal stromal tumors (GIST)]
    H U Schildhaus
    Institut fur Pathologie, Universitatsklinikum Bonn, Sigmund Freud Strasse 25, Bonn, Germany
    Radiologe 49:1104-8. 2009
  8. doi request reprint [Gastrointestinal stromal tumors of the stomach. Updates and differences compared to other locations]
    E Wardelmann
    Institut fur Pathologie, Universitatsklinikum Bonn, Sigmund Freud Str 25, 53127 Bonn
    Pathologe 31:195-8. 2010
  9. ncbi request reprint [Activating mutations in receptor tyrosine kinases with relevance for treatment of gastrointestinal stromal tumors]
    E Wardelmann
    Institut fur Pathologie, Universitatsklinikum Bonn
    Verh Dtsch Ges Pathol 91:165-8. 2007
  10. doi request reprint [Are sarcoma centers needed in Germany? Experience gained with the Bonner GIST register]
    E Wardelmann
    Institut fur Pathologie, Universitatsklinikum Bonn, Sigmund Freud Str 25, 53127 Bonn, Deutschland
    Pathologe 32:72-5. 2011

Collaborators

  • E Wardelmann
  • P Hohenberger
  • G Mikuz
  • P Reichardt
  • L C Heukamp
  • N Friedrichs
  • Sabine Merkelbach-Bruse
  • S Merkelbach-Bruse
  • Jana Fassunke
  • Wilko I Staiger
  • H Künstlinger
  • R Buttner
  • Florian Haller
  • Marie Christine Blum
  • Antje Krohn
  • Andreas Gaumann
  • Marc Zapatka
  • Regine Schneider-Stock
  • Gunhild Mechtersheimer
  • Julia Kitz
  • Benedikt Brors
  • Reinhard Buttner
  • Ronald Simon
  • Roland Penzel
  • Wolfgang Dietmaier
  • Helen Künstlinger
  • Laszlo Fuzesi
  • Ulrich Ronellenfitsch
  • Matthias Hm Schwarzbach
  • Georg Kaehler
  • Antonia Dimitrakopoulou-Strauss

Detail Information

Publications13

  1. pmc The Merendino procedure following preoperative imatinib mesylate for locally advanced gastrointestinal stromal tumor of the esophagogastric junction
    Wilko I Staiger
    Div, Surgical Oncology and Thoracic Surgery, Department of Surgery, University Hospital Mannheim, Medical Faculty Mannheim, University of Heidelberg, Germany
    World J Surg Oncol 6:37. 2008
    ..If locally advanced, extended or multivisceral resection with relevant procedural-specific morbidity and mortality is often necessary...
  2. pmc qPCR in gastrointestinal stromal tumors: Evaluation of reference genes and expression analysis of KIT and the alternative receptor tyrosine kinases FLT3, CSF1-R, PDGFRB, MET and AXL
    Jana Fassunke
    Department of Pathology, University of Bonn Medical Center, Bonn, Germany
    BMC Mol Biol 11:100. 2010
    ..wt-GIST were compared to samples with mutations in KIT exon 9 and 11 and PDGFRA exon 18 in order to evaluate whether overexpression of these alternative RTK might contribute to the pathogenesis of wt-GIST...
  3. pmc Pitfalls in mutational testing and reporting of common KIT and PDGFRA mutations in gastrointestinal stromal tumors
    Sabine Merkelbach-Bruse
    Department of Pathology, University of Bonn Medical School, Sigmund Freud Str, 25 D 53127 Bonn, Germany
    BMC Med Genet 11:106. 2010
    ..In Germany, there are still no general rules how to perform mutational analysis...
  4. doi request reprint [Inflammatory fibroid polyp: from Vanek's "submucosal granuloma" to the concept of submucosal mesenchymal neoplasia]
    H U Schildhaus
    Institut fur Pathologie, Universitatsklinikum Bonn, Sigmund Freud Str 25, 53127, Bonn, Deutschland
    Pathologe 31:109-14. 2010
    ..Recent data show that the spindle cells express PDGFRA, and the majority of IFP harbour activating PDGFRA mutations. Therefore, IFP represent true benign mesenchymal tumors of the gastrointestinal tract...
  5. doi request reprint [Malignant mixed Müllerian tumor of the urinary bladder]
    H U Schildhaus
    Institut fur Pathologie, Universitatsklinikum Bonn, Sigmund Freud Strasse 25, 53127, Bonn
    Pathologe 29:375-7. 2008
    ..To the best of our knowledge, such a neoplasm has not yet been reported in the literature...
  6. doi request reprint [Inflammatory fibroid polyps are true neoplasms with PDGFRA mutations]
    H U Schildhaus
    Institut fur Pathologie, Universitatsklinikum Bonn, Sigmund Freud Str 25, 53127 Bonn
    Pathologe 30:117-20. 2009
    ..IFP occur in the stomach, small bowel, colon and esophagus. To date, etiology and pathogenesis are unclear...
  7. doi request reprint [Pathology and molecular biology of gastrointestinal stromal tumors (GIST)]
    H U Schildhaus
    Institut fur Pathologie, Universitatsklinikum Bonn, Sigmund Freud Strasse 25, Bonn, Germany
    Radiologe 49:1104-8. 2009
    ..This treatment has become the gold standard in the last few years with only few side effects. Knowledge of the underlying KIT or PDGFRA mutation is both relevant for the prognosis and treatment response...
  8. doi request reprint [Gastrointestinal stromal tumors of the stomach. Updates and differences compared to other locations]
    E Wardelmann
    Institut fur Pathologie, Universitatsklinikum Bonn, Sigmund Freud Str 25, 53127 Bonn
    Pathologe 31:195-8. 2010
    ..This present article provides an overview of these differences also with regard to possible therapeutic consequences...
  9. ncbi request reprint [Activating mutations in receptor tyrosine kinases with relevance for treatment of gastrointestinal stromal tumors]
    E Wardelmann
    Institut fur Pathologie, Universitatsklinikum Bonn
    Verh Dtsch Ges Pathol 91:165-8. 2007
    ..Our own observations show that the location of the underlying mutations influence the response to treatment with imatinib...
  10. doi request reprint [Are sarcoma centers needed in Germany? Experience gained with the Bonner GIST register]
    E Wardelmann
    Institut fur Pathologie, Universitatsklinikum Bonn, Sigmund Freud Str 25, 53127 Bonn, Deutschland
    Pathologe 32:72-5. 2011
    ..The introduction of epidemiological as well as interdisciplinary sarcoma registers is a prerequisite for the improvement of sarcoma diagnostics and therapy...
  11. ncbi request reprint [Therapeutic targets in gastrointestinal stromal tumors]
    E Wardelmann
    Institut fur Pathologie, Universitatsklinikum Bonn
    Verh Dtsch Ges Pathol 90:73-9. 2006
    ..In summary, mutational status in KIT or PDGF receptor alpha of GISTs is relevant for prognosis, for response to treatment and for further insights into mechanisms of treatment failure...
  12. doi request reprint [Molecular methods in the diagnosis of sarcoma]
    S Merkelbach-Bruse
    Institut fur Pathologie, Universitatsklinikum Bonn, Sigmund Freud Str 25, 53127 Bonn, Deutschland
    Pathologe 32:24-31. 2011
    ..Here we review the most important molecular techniques currently used in sarcoma diagnosis, describe their relevance for differential diagnosis and point out specific examples...
  13. ncbi request reprint Extraosseous osteosarcoma arising from the small intestinal mesentery
    L C Heukamp
    Institute of Pathology, University Hospital Bonn, Sigmund Freud Str 25, 53127 Bonn, Germany
    Pathol Res Pract 203:473-7. 2007
    ..Diagnosis, management, and outcome in the context of the current literature are discussed. To our knowledge, this is the first description of an extraosseous osteosarcomas in the small bowel mesentery in the literature...