M Schepke

Summary

Affiliation: University of Bonn
Country: Germany

Publications

  1. ncbi Propranolol stereoisomer plasma concentrations and portal haemodynamic response in patients with liver cirrhosis
    M Schepke
    Department of Internal Medicine I, University of Bonn, Bonn, Germany
    Aliment Pharmacol Ther 13:1451-8. 1999
  2. ncbi Hemodynamic effects of the angiotensin II receptor antagonist irbesartan in patients with cirrhosis and portal hypertension
    M Schepke
    Department of Internal Medicine I, University of Bonn, Sigmund Freud Strasse 25, D 53127 Bonn, Germany
    Gastroenterology 121:389-95. 2001
  3. ncbi Acute haemodynamic effects of losartan in anaesthetized cirrhotic rats
    J Heller
    Department of Internal Medicine I, University of Bonn, Bonn, Germany
    Eur J Clin Invest 33:1006-12. 2003
  4. ncbi Contractile hyporesponsiveness of hepatic arteries in humans with cirrhosis: evidence for a receptor-specific mechanism
    M Schepke
    Department of Internal Medicine I, University of Bonn, Bonn, Germany
    Hepatology 34:884-8. 2001
  5. ncbi Short-term effects of transjugular intrahepatic shunt on cardiac function assessed by cardiac MRI: preliminary results
    A Kovacs
    Department of Radiology, University of Bonn, Sigmund Freud Str 25, 53105 Bonn, Germany
    Cardiovasc Intervent Radiol 33:290-6. 2010
  6. ncbi Portal hypertension is associated with increased mRNA levels of vasopressor G-protein-coupled receptors in human hepatic arteries
    M Neef
    Department of Internal Medicine I, University of Bonn, Bonn, Germany
    Eur J Clin Invest 33:249-55. 2003
  7. ncbi Hemodynamic effects of propranolol and nitrates in cirrhotics with transjugular intrahepatic portosystemic stent-shunt
    K A Brensing
    Dept of Internal Medicine, University of Bonn, Germany
    Scand J Gastroenterol 37:1070-6. 2002
  8. ncbi A patient with portal hypertension and blindness after transjugular intrahepatic portosystemic shunt
    Beate Appenrodt
    Department of Internal Medicine I, University of Bonn, Bonn, Germany
    Eur J Gastroenterol Hepatol 18:447-9. 2006
  9. ncbi [Chronic diarrhea in a 43-year-old patient]
    J Strehl
    Medizinische Klinik und Poliklinik I, Universitätsklinik Bonn
    Internist (Berl) 44:626-30. 2003
  10. ncbi [Variceal hemorrhage: primary and secondary prophylaxis]
    T Sauerbruch
    , Allgemeine Innere Medizin, Bonn
    Dtsch Med Wochenschr 129:S68-70. 2004

Detail Information

Publications17

  1. ncbi Propranolol stereoisomer plasma concentrations and portal haemodynamic response in patients with liver cirrhosis
    M Schepke
    Department of Internal Medicine I, University of Bonn, Bonn, Germany
    Aliment Pharmacol Ther 13:1451-8. 1999
    ..The haemodynamic effect of propranolol on portal pressure in patients with portal hypertension is highly variable and does not correlate with propranolol racemate plasma concentrations...
  2. ncbi Hemodynamic effects of the angiotensin II receptor antagonist irbesartan in patients with cirrhosis and portal hypertension
    M Schepke
    Department of Internal Medicine I, University of Bonn, Sigmund Freud Strasse 25, D 53127 Bonn, Germany
    Gastroenterology 121:389-95. 2001
    ..This randomized, placebo-controlled, double-blind study aimed to assess the effect of the angiotensin II receptor antagonist irbesartan on portal and systemic hemodynamics and renal function in patients with cirrhosis...
  3. ncbi Acute haemodynamic effects of losartan in anaesthetized cirrhotic rats
    J Heller
    Department of Internal Medicine I, University of Bonn, Bonn, Germany
    Eur J Clin Invest 33:1006-12. 2003
    ..The angiotensin II type 1 receptor antagonist losartan has been suggested as a portal pressure-lowering drug in patients with cirrhosis...
  4. ncbi Contractile hyporesponsiveness of hepatic arteries in humans with cirrhosis: evidence for a receptor-specific mechanism
    M Schepke
    Department of Internal Medicine I, University of Bonn, Bonn, Germany
    Hepatology 34:884-8. 2001
    ..Hence, the cause of the hyporesponsiveness to some vasoconstrictors in cirrhosis appears to be a receptor-specific phenomenon localized upstream from the G-protein level...
  5. ncbi Short-term effects of transjugular intrahepatic shunt on cardiac function assessed by cardiac MRI: preliminary results
    A Kovacs
    Department of Radiology, University of Bonn, Sigmund Freud Str 25, 53105 Bonn, Germany
    Cardiovasc Intervent Radiol 33:290-6. 2010
    ..Normalization of cardiac dimensions was observed after months together with mild left ventricular hypertrophy...
  6. ncbi Portal hypertension is associated with increased mRNA levels of vasopressor G-protein-coupled receptors in human hepatic arteries
    M Neef
    Department of Internal Medicine I, University of Bonn, Bonn, Germany
    Eur J Clin Invest 33:249-55. 2003
    ....
  7. ncbi Hemodynamic effects of propranolol and nitrates in cirrhotics with transjugular intrahepatic portosystemic stent-shunt
    K A Brensing
    Dept of Internal Medicine, University of Bonn, Germany
    Scand J Gastroenterol 37:1070-6. 2002
    ..TIPS-treated patients might therefore profit from additive propranolol therapy allowing limited shunts to be applied initially and/or to reduce the need for TIPS revisions in the case of shunt-dysfunction during follow-up...
  8. ncbi A patient with portal hypertension and blindness after transjugular intrahepatic portosystemic shunt
    Beate Appenrodt
    Department of Internal Medicine I, University of Bonn, Bonn, Germany
    Eur J Gastroenterol Hepatol 18:447-9. 2006
    ..The present case report shows a very rare but important complication after TIPS implantation. To avoid this complication it is recommended to perform echocardiography before all TIPS placements...
  9. ncbi [Chronic diarrhea in a 43-year-old patient]
    J Strehl
    Medizinische Klinik und Poliklinik I, Universitätsklinik Bonn
    Internist (Berl) 44:626-30. 2003
    ..Treatment consisted of a protein-rich diet, with reduced fat content enriched by middle-chain fatty acids, as well as twice-daily injections of 200 micrograms octreotide. With this therapy, the symptoms improved...
  10. ncbi [Variceal hemorrhage: primary and secondary prophylaxis]
    T Sauerbruch
    , Allgemeine Innere Medizin, Bonn
    Dtsch Med Wochenschr 129:S68-70. 2004
  11. ncbi [Primary prevention of variceal bleeding in cirrhosis]
    M Schepke
    , Bonn
    Dtsch Med Wochenschr 131:1269-72. 2006
  12. ncbi Magnetic resonance (MR) imaging and MR angiography for evaluation and follow-up of hepatic artery banding in patients with hepatic involvement of hereditary hemorrhagic telangiectasia
    W A Willinek
    Department of Radiology, University of Bonn, Sigmund Freud Strasse 25, D 53105 Bonn, Germany
    Abdom Imaging 31:694-700. 2006
    ....
  13. ncbi Combination of bilateral metal stenting and trans-stent photodynamic therapy for palliative treatment of hilar cholangiocarcinoma
    T Gerhardt
    Department of Internal Medicine I, University Hospital, Bonn, Germany
    Z Gastroenterol 48:28-32. 2010
    ..3 +/- 15.8 vs. 14.4 +/- 22.5 days; p = 0.54). Bilateral insertion of Jostent SelfX in patients with proximal cholangiocarcinoma is feasible and effective and can be safely combined with trans-stent photodynamic therapy...
  14. ncbi Biliary metal stents and air embolism: a note of caution
    C Rabe
    Department of Medicine I, University of Bonn, Bonn, Germany
    Endoscopy 38:648-50. 2006
    ..It is likely that the large diameter of metal stents and the potential for these stents to lacerate venous structures facilitate the entry of air into the venous circulation, an event which may have life-threatening consequences...
  15. ncbi [Gastrointestinal bleeding in portal hypertension in liver cirrhosis]
    E Biecker
    Medizinische Klinik und Poliklinik I,
    Z Gastroenterol 43:35-46. 2005
    ..Bleeding from ectopic varices and bleeding from hypertensive gastropathy should be treated individually either by endoscopy, TIPS or drug therapy...
  16. ncbi [MRI in cavernous transformation of the portal vein: secondary biliary abnormalities and portoportal collaterals]
    R Schaible
    Radiologische Klinik, , Germany
    Rofo 174:1408-14. 2002
    ..These collaterals frequently alter the biliary system, which must be considered in differential diagnosis of biliary abnormalities observed in the presence of portoportal collaterals...
  17. ncbi Transjugular intrahepatic portosystemic shunting is not superior to endoscopic variceal band ligation for prevention of variceal rebleeding in cirrhotic patients: a randomized, controlled trial
    V Gulberg
    Dept of Medicine II and Institute for Clinical Radiology, Klinikum of the University of Munich Grosshadern, Munich, Germany
    Scand J Gastroenterol 37:338-43. 2002
    ..The aim of the present study was to compare the transjugular intrahepatic portosystemic shunt (TIPS) with variceal band ligation (VBL) in the prophylaxis of variceal rebleeding in patients with cirrhosis of the liver...