P D Schellinger

Summary

Affiliation: University of Heidelberg
Country: Germany

Publications

  1. ncbi A standardized MRI stroke protocol: comparison with CT in hyperacute intracerebral hemorrhage
    P D Schellinger
    Department of Neurology, Medical Faculty, University of Heidelberg, Germany
    Stroke 30:765-8. 1999
  2. ncbi Characteristics and outcome of patients with early complete neurological recovery after thrombolysis for acute ischemic stroke
    C Blinzler
    Department of Neurology, University of Erlangen Nuremberg, Erlangen, Germany
    Cerebrovasc Dis 31:185-90. 2011
  3. ncbi Safety and outcome after thrombolysis in stroke patients with mild symptoms
    M Kohrmann
    Department of Neurology, University of Erlangen, Schwabachanlage 6, Erlangen, Germany
    Cerebrovasc Dis 27:160-6. 2009
  4. ncbi Feasibility and safety of moderate hypothermia after massive hemispheric infarction
    S Schwab
    Department of Neurology, University of Heidelberg, Germany
    Stroke 32:2033-5. 2001
  5. ncbi Effect of incomplete (spontaneous and postthrombolytic) recanalization after middle cerebral artery occlusion: a magnetic resonance imaging study
    T Neumann-Haefelin
    Department of Neurology, University Hospitals, Frankfurt, Germany
    Stroke 35:109-14. 2004
  6. ncbi Stroke magnetic resonance imaging within 6 hours after onset of hyperacute cerebral ischemia
    P D Schellinger
    Department of Neurology, University of Heidelberg Medical School, Germany
    Ann Neurol 49:460-9. 2001
  7. ncbi Neurometabolic changes during treatment with moderate hypothermia in a patient suffering from severe middle cerebral artery infarction
    W R Schäbitz
    Department of Neurology, University of Heidelberg Medical School, Heidelberg, Germany
    Cerebrovasc Dis 12:298-302. 2001
  8. ncbi Thrombolytic therapy for ischemic stroke--a review. Part I--Intravenous thrombolysis
    P D Schellinger
    Department of Neurology, University of Heidelberg, Heidelberg, Germany
    Crit Care Med 29:1812-8. 2001
  9. ncbi Effect and feasibility of controlled rewarming after moderate hypothermia in stroke patients with malignant infarction of the middle cerebral artery
    T Steiner
    Department of Neurology, University of Heidelberg, Heidelberg, Germany
    Stroke 32:2833-5. 2001
  10. ncbi Influence of intraventricular fibrinolytic therapy with rt-PA on the long-term outcome of treated patients with spontaneous basal ganglia hemorrhage: a case-control study
    H B Huttner
    Department of Neurology, University of Erlangen, Erlangen, Germany
    Eur J Neurol 15:342-9. 2008

Detail Information

Publications42

  1. ncbi A standardized MRI stroke protocol: comparison with CT in hyperacute intracerebral hemorrhage
    P D Schellinger
    Department of Neurology, Medical Faculty, University of Heidelberg, Germany
    Stroke 30:765-8. 1999
    ..The purpose of our study was to determine the diagnostic accuracy of a standardized, multimodal MRI (mMRI) stroke protocol in the qualitative and quantitative assessment of hyperacute ICH (<6 hours)...
  2. ncbi Characteristics and outcome of patients with early complete neurological recovery after thrombolysis for acute ischemic stroke
    C Blinzler
    Department of Neurology, University of Erlangen Nuremberg, Erlangen, Germany
    Cerebrovasc Dis 31:185-90. 2011
    ..This study analyzes demographic and clinical characteristics of patients with early complete neurological recovery after thrombolysis...
  3. ncbi Safety and outcome after thrombolysis in stroke patients with mild symptoms
    M Kohrmann
    Department of Neurology, University of Erlangen, Schwabachanlage 6, Erlangen, Germany
    Cerebrovasc Dis 27:160-6. 2009
    ..We aimed to assess the safety and outcome of thrombolysis therapy in patients with minor but disabling stroke symptoms...
  4. ncbi Feasibility and safety of moderate hypothermia after massive hemispheric infarction
    S Schwab
    Department of Neurology, University of Heidelberg, Germany
    Stroke 32:2033-5. 2001
    ..This multicenter study was performed to evaluate (1) the safety and feasibility of moderate hypothermia and (2) its potential to reduce intracranial hypertension in acute stroke patients...
  5. ncbi Effect of incomplete (spontaneous and postthrombolytic) recanalization after middle cerebral artery occlusion: a magnetic resonance imaging study
    T Neumann-Haefelin
    Department of Neurology, University Hospitals, Frankfurt, Germany
    Stroke 35:109-14. 2004
    ..The purpose of this study was to analyze the frequency and relevance of incomplete recanalization for tissue and clinical outcome...
  6. ncbi Stroke magnetic resonance imaging within 6 hours after onset of hyperacute cerebral ischemia
    P D Schellinger
    Department of Neurology, University of Heidelberg Medical School, Germany
    Ann Neurol 49:460-9. 2001
    ..Patients with proximal vessel occlusions have a larger amount of tissue at risk, a lower recanalization rate, and a worse outcome. Urgent recanalization seems to be of utmost importance for these patients...
  7. ncbi Neurometabolic changes during treatment with moderate hypothermia in a patient suffering from severe middle cerebral artery infarction
    W R Schäbitz
    Department of Neurology, University of Heidelberg Medical School, Heidelberg, Germany
    Cerebrovasc Dis 12:298-302. 2001
    ..Microdialysis monitoring of therapeutic hypothermia in severe hemispheric infarction might be a useful additional monitoring tool to assess the status of the brain and to predict further deterioration...
  8. ncbi Thrombolytic therapy for ischemic stroke--a review. Part I--Intravenous thrombolysis
    P D Schellinger
    Department of Neurology, University of Heidelberg, Heidelberg, Germany
    Crit Care Med 29:1812-8. 2001
    ..If applied more widely, thrombolytic therapy may result in profound cost savings in health care and reduction of long-term disability of stroke patients...
  9. ncbi Effect and feasibility of controlled rewarming after moderate hypothermia in stroke patients with malignant infarction of the middle cerebral artery
    T Steiner
    Department of Neurology, University of Heidelberg, Heidelberg, Germany
    Stroke 32:2833-5. 2001
    ..However, during passive rewarming, ICP continuously rises and some patients suffer transtentorial herniation...
  10. ncbi Influence of intraventricular fibrinolytic therapy with rt-PA on the long-term outcome of treated patients with spontaneous basal ganglia hemorrhage: a case-control study
    H B Huttner
    Department of Neurology, University of Erlangen, Erlangen, Germany
    Eur J Neurol 15:342-9. 2008
    ..The results of the prospective randomized trial (Clot Lysis: Evaluating Accelerated Resolution of Intraventricular Hemorrhage) need to be awaited...
  11. ncbi Feasibility and safety of magnetic resonance imaging-based thrombolysis in patients with stroke on awakening: initial single-centre experience
    L Breuer
    Department of Neurology, University of Erlangen Nuremberg, Erlangen, Germany
    Int J Stroke 5:68-73. 2010
    ..Up to 25% of all acute ischaemic strokes occur during sleep. Because of the unclear time window, patients with stroke on awakening are usually not considered for acute therapy and excluded from most acute treatment trials...
  12. ncbi Thrombolytic therapy for ischemic stroke--a review. Part II--Intra-arterial thrombolysis, vertebrobasilar stroke, phase IV trials, and stroke imaging
    P D Schellinger
    Department of Neurology, University of Heidelberg, Heidelberg, Germany
    Crit Care Med 29:1819-25. 2001
    ..If applied more widely, thrombolytic therapy may result in profound cost savings in health care and reduction of long-term disability of stroke patients...
  13. ncbi Effect of intravenous thrombolysis on MRI parameters and functional outcome in acute stroke <6 hours
    J Rother
    Department of Neurology, University Hospital, Hamburg Eppendorf, Germany
    Stroke 33:2438-45. 2002
    ....
  14. ncbi MRI in acute subarachnoid haemorrhage; findings with a standardised stroke protocol
    J B Fiebach
    Division of Neuroradiology, Department of Neurology, University of Heidelberg Medical Centre, Im Neuenheimer Feld 400, 69120, Germany
    Neuroradiology 46:44-8. 2004
    ..Perfusion maps were normal in all cases. MRA and conventional angiography revealed an aneurysm in only one patient. Stroke MRI within 6 h of SAH thus shows a characteristic pattern...
  15. ncbi Thrombolytic therapy within 3 to 6 hours after onset of ischemic stroke: useful or harmful?
    P A Ringleb
    Department of Neurology, University of Heidelberg, Heidelberg, Germany
    Stroke 33:1437-41. 2002
    ....
  16. ncbi Masking of vertebral artery dissection by severe trauma to the cervical spine
    P D Schellinger
    Department of Neurology, University of Heidelberg, Germany
    Spine (Phila Pa 1976) 26:314-9. 2001
    ..A prospective case study was performed...
  17. ncbi Poliomyelitic-like illness in central European encephalitis
    P D Schellinger
    Department of Neurology, University of Heidelberg, Germany
    Neurology 55:299-302. 2000
    ..Autopsy in one patient showed severe cervicothoracic inflammation with changes almost exclusively in anterior horn cells and roots, as typically seen in poliomyelitis...
  18. ncbi Serial analysis of the apparent diffusion coefficient time course in human stroke
    J B Fiebach
    Department of Neuroradiology, University of Heidelberg, Medical School, Kopfklinik, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany
    Neuroradiology 44:294-8. 2002
    ..Furthermore, the age of an ischemia can be determined and multiple strokes can be distinguished from a single progressive stroke...
  19. ncbi Diagnostic accuracy of MRI compared to CCT in patients with brain metastases
    P D Schellinger
    Department of Neurology, University of Heidelberg, Germany
    J Neurooncol 44:275-81. 1999
    ..Therefore, in patients with solitary BM according to diagnostic contrast-enhanced computed tomography (CCT), we investigated, what additional information could be gained by contrast-enhanced magnetic resonance imaging (MRI)...
  20. ncbi Clopidogrel in the management of cerebrovascular events
    P A Ringleb
    Department of Neurology, University of Heidelberg, Heidelberg, Germany
    Int J Clin Pract 58:402-10. 2004
    ..Cost-effectiveness studies predict up to tenfold higher cost in the prevention of vascular events when compared to ASA, in times of shrinking health budgets a topic of interest...
  21. ncbi Neuroprotective effect of delayed moderate hypothermia after focal cerebral ischemia: an MRI study
    R Kollmar
    Department of Neurology, University of Heidelberg, Heidelberg, Germany
    Stroke 33:1899-904. 2002
    ..We examined the influence of delayed hypothermia on secondary ischemic injury, MRI lesion size, and neurological outcome after transient focal cerebral ischemia in a rat model...
  22. ncbi Serial diffusion and perfusion MRI analysis of the perihemorrhagic zone in a rat ICH model
    B Orakcioglu
    Department of Neurosurgery, University Hospital Heidelberg, Heidelberg, Germany
    Acta Neurochir Suppl 103:15-8. 2008
    ..We aimed to examine perihemorrhagic changes with an animal experimental MRI study using a stroke-MRI protocol. In a subset of animals the feasibility and effects of stereotactic hematoma evacuation was investigated...
  23. ncbi [European Stroke Organisation 2008 guidelines for managing acute cerebral infarction or transient ischemic attack. Part 1]
    P Ringleb
    Neurologische Klinik, Im Neuenheimer Feld 400, 69120, Heidelberg
    Nervenarzt 79:936-57. 2008
  24. ncbi [Thrombolysis for ischemic stroke: an update]
    M Kohrmann
    Neurologische Universitatsklinik, Schwabachanlage 6, 91054 Erlangen
    Nervenarzt 78:393-405. 2007
    ..Even though no randomized trials are available intraarterial thrombolysis is the treatment of choice for acute basilar occlusion, but if this intervention is not available an intravenous approach may be an equal alternative...
  25. ncbi [Effective acute stroke treatment beyond approval limitations: intravenous thrombolysis within an extended time window (3-6 h) and in old patients (aged 80 or older)]
    G Thomalla
    Klinik und Poliklinik fur Neurologie, Neuro Zentrum, Universitatsklinikum Hamburg Eppendorf, Hamburg
    Fortschr Neurol Psychiatr 75:343-50. 2007
    ..To summarize, we recommend experienced stroke centres to treat acute stroke patients with thrombolysis up to 6 hours using MRI criteria for patient selection, and to treat also patients aged 80 years or older...
  26. ncbi [Warning symptom TIA--role of the general practitioner]
    P D Schellinger
    Neurologische Klinik,
    MMW Fortschr Med 150:25-6, 28. 2008
  27. ncbi EFNS guideline on neuroimaging in acute stroke. Report of an EFNS task force
    J C Masdeu
    Department of Neurology and Neurosurgery, University of Navarra, Pamplona, Spain
    Eur J Neurol 13:1271-83. 2006
    ..Currently, single photon emission computed tomography and positron emission tomography have a more limited role in the evaluation of the acute stroke patient...
  28. ncbi [Intracerebral hemorrhage related to anticoagulant therapy]
    H B Huttner
    Abteilung fur Neurologie, Ruprecht Karls Universitat Heidelberg, Im Neuenheimer Feld 400, 69120, Heidelberg
    Nervenarzt 77:671-2, 674-6, 678-81. 2006
    ..This article reviews the epidemiology of OAT-ICH, its pathophysiology, and current treatment options and discusses open questions with particular respect to more recent pharmacological therapies...
  29. ncbi Is old age really a reason to withhold thrombolytic therapy?
    C Schwark
    J Neurol Neurosurg Psychiatry 77:289. 2006
  30. ncbi [Acute cerebral circulation problems]
    P D Schellinger
    Neurologische Klinik, Universitatsklinikum Heidelberg
    Internist (Berl) 46:982-93. 2005
    ....
  31. ncbi CT and diffusion-weighted MR imaging in randomized order: diffusion-weighted imaging results in higher accuracy and lower interrater variability in the diagnosis of hyperacute ischemic stroke
    J B Fiebach
    Department of Neuroradiology, University of Heidelberg Medical School, Heidelberg, Germany
    Stroke 33:2206-10. 2002
    ..The value of this method as a routine procedure is still being discussed. In previous studies, CT was always performed before DWI. Therefore, infarct progression could be a reason for the better result in DWI...
  32. ncbi [Myxedema coma as a rare differential diagnosis of severe consciousness disturbance]
    R Kollmar
    Neurologische Klinik, Universitat Heidelberg
    Nervenarzt 73:1183-5. 2002
    ..In conclusion, treatment of the myxedema coma must be started as soon as the laboratory results are confirmatory, since its course depends on the time of initiation of treatment...
  33. ncbi [Modern magnetic resonance techniques in stroke]
    J B Fiebach
    Abteilung Neuroradiologie, Neurologische Klinik, Universitatsklinikum Heidelberg
    Radiologe 43:251-63; quiz 263-4. 2003
    ..Besides presenting an explanation of the basic principles of modern stroke MR imaging, typical results of MR perfusion measurements and the appearance of hemorrhages on MR will be explained...
  34. ncbi [Diagnostics and treatment of acute stroke]
    P D Schellinger
    Neurologische Klinik und Neuroradiologie,
    Fortschr Neurol Psychiatr 71:423-38; quiz 439-40. 2003
  35. ncbi [Hepatic encephalopathy]
    P D Schellinger
    Neurologische Klinik, Universitatsklinikum Heidelberg
    Nervenarzt 74:1078-87. 2003
    ..The prognosis depends ultimately on the course of the liver disease...
  36. ncbi [Modern nuclear magnetic resonance techniques in stroke]
    J B Fiebach
    Abteilung Neuroradiologie, Neurologische Klinik, Universitatsklinikum Heidelberg, Im Neuenheimer Feld 400, 69120 Heidelberg
    Nervenarzt 73:104-16; quiz 116-7. 2002
    ..Besides presenting an explanation of the basic principles of modern stroke MR imaging, typical results of MR perfusion measurements and the appearance of hemorrhages on MR will be explained...
  37. ncbi [Value of modern CT-techniques in the diagnosis of acute stroke]
    P D Schellinger
    Neurologische Klinik, Universitatsklinikum Heidelberg
    Radiologe 44:380-8. 2004
    ..While stroke MRI seems to be the upcoming standard, due to its low availability the need for an improved CT-based patient selection is evident...
  38. ncbi [The value of platelet inhibitors in the secondary prophylaxis of stroke -- a review]
    P D Schellinger
    Neurologische Klinik, Universitatsklinikum Heidelberg
    Fortschr Neurol Psychiatr 72:270-81. 2004
    ..The aim of this article is a summary and critical review of all relevant studies and meta-analyses for secondary prevention of stroke and to give a differentiated therapeutic recommendation...
  39. ncbi Magnetic resonance imaging criteria for thrombolysis in acute cerebral infarct
    N Hjort
    Department of Neuroradiology, Center for Functionally Integrative Neuroscience, Arhus University Hospital, Nørrebrogade 44, 8000 Arhus C, Denmark
    Stroke 36:388-97. 2005
    ....
  40. ncbi [Diffusion and perfusion MR imaging in stroke]
    J B Fiebach
    Institut fur Diagnostische und Interventionelle Radiologie und Neuroradiologie, Universitatsklinikum Essen
    Radiologe 45:412-4, 416-9. 2005
    ..Whether MRI is also appropriate as an aid to reaching a prognosis on the risk of secondary hemorrhage has not yet been resolved...
  41. ncbi Thrombolytic therapy for acute ischaemic stroke in octogenarians: selection by magnetic resonance imaging improves safety but does not improve outcome
    P A Ringleb
    Neurologische Klinik der Ruprecht Karls Universität Heidelberg, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany
    J Neurol Neurosurg Psychiatry 78:690-3. 2007
    ..Owing to the fear of an increased bleeding risk, thrombolytic therapy is withheld from many patients with acute stroke > 80 years of age...
  42. ncbi [Nocturnal spinal fracture--first manifestation of epilepsy]
    T A Rupprecht
    Neurologische Klinik,
    Unfallchirurg 104:179-80. 2001
    ..Vertebral fractures unrelated to an exogenous trauma are therefore always suspicious of an underlying epileptic disease...