Research Topics
Genomes and GenesSpecies | Gustav SchellingSummaryAffiliation: University of Munich Country: Germany Publications
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Detail Information
Publications
The effect of stress doses of hydrocortisone during septic shock on posttraumatic stress disorder and health-related quality of life in survivorsG Schelling
Department of Anaesthesiology, Ludwig Maximilians University, Munich, Germany
Crit Care Med 27:2678-83. 1999..The administration of stress doses of hydrocortisone during treatment in the intensive care unit could theoretically result in a lower incidence of PTSD. We tested this hypothesis in survivors of septic shock...- Pulmonary function and health-related quality of life in a sample of long-term survivors of the acute respiratory distress syndromeG Schelling
Department of Anesthesiology, Klinikum Grosshadern, Ludwig Maximilians University, Munich, Germany
Intensive Care Med 26:1304-11. 2000..We performed a follow-up cohort analysis in order to delineate the correlation between pulmonary function (PF) and health-related quality of life (HRQL) in patients after ARDS... - Effects of stress hormones on traumatic memory formation and the development of posttraumatic stress disorder in critically ill patientsGustav Schelling
Department of Anesthesiology, Ludwig Maximilians University, 81377 Munich, Germany
Neurobiol Learn Mem 78:596-609. 2002..Our studies also demonstrate that animal models of aversive learning are useful in analyzing and predicting clinical findings in critically ill humans... 
Anandamide and neutrophil function in patients with fibromyalgiaInes Kaufmann
Clinic of Anaesthesiology, Klinikum Grosshadern, Ludwig Maximilians University, Marchioninistrasse 15, 81366 Munich, Germany
Psychoneuroendocrinology 33:676-85. 2008..In conclusion, patients with FM might benefit from pharmacologic manipulation of endocannabinoid signaling which should be tested in controlled studies...- Traumatic memories, post-traumatic stress disorder and serum cortisol levels in long-term survivors of the acute respiratory distress syndromeDaniela Hauer
Department of Anaesthesiology, Ludwig Maximilians University, Munich, Germany
Brain Res 1293:114-20. 2009.... - Stress doses of hydrocortisone, traumatic memories, and symptoms of posttraumatic stress disorder in patients after cardiac surgery: a randomized studyGustav Schelling
Department of Anesthesiology, Ludwig-Maximilians-University, Munich, Germany
Biol Psychiatry 55:627-33. 2004..CONCLUSIONS: Stress doses of hydrocortisone in patients undergoing CS are associated with a lower intensity of chronic stress and PTSD symptoms at 6 months after CS... - Stress doses of hydrocortisone in high-risk patients undergoing cardiac surgery: effects on interleukin-6 to interleukin-10 ratio and early outcomeFlorian Weis
Department of Anesthesiology, University of Munich, Klinikum Grosshadern, Munich, Germany
Crit Care Med 37:1685-90. 2009..Stress doses of hydrocortisone have been successfully used to improve outcome of CS. The interleukin (IL)-6 to IL-10 ratio is associated with outcome after trauma and major surgery... - Decrease in adhesion molecules on polymorphonuclear leukocytes of patients with fibromyalgiaInes Kaufmann
Department of Anesthesiology, Klinikum Grosshadern, Ludwig Maximilians University, Marchioninistrasse 15, 81366, Munich, Germany
Rheumatol Int 29:1109-11. 2009..01) and CD11b/CD18 (p < 0.05) on polymorphonuclear leukocytes. These changes might lower the rate of polymorphonuclear leukocyte migration to sites of inflammation and thereby compromise defense against infections and pain control... - Stress doses of hydrocortisone in septic shock: beneficial effects on opsonization-dependent neutrophil functionsInes Kaufmann
Ludwig Maximilians University, Klinikum Grosshadern, Clinic of Anesthesiology, 81377 Munich, Germany
Intensive Care Med 34:344-9. 2008..To assess the effects of stress doses of hydrocortisone (HC) on clinical parameters and neutrophil functions in patients with septic shock... - Effect of an acute consumption of a moderate amount of ethanol on plasma endocannabinoid levels in humansMatthias Feuerecker
Department of Anaesthesiology, Klinikum Grosshadern, University of Munich, Germany
Alcohol Alcohol 47:226-32. 2012..Grape juice or plain non-sparkling water served as non-alcoholic control liquids... - Stress doses of hydrocortisone reduce chronic stress symptoms and improve health-related quality of life in high-risk patients after cardiac surgery: a randomized studyFlorian Weis
Department of Anesthesiology, Ludwig-Maximilians-University, Munich, Germany
J Thorac Cardiovasc Surg 131:277-82. 2006.... - Relationship of a common polymorphism of the glucocorticoid receptor gene to traumatic memories and posttraumatic stress disorder in patients after intensive care therapyDaniela Hauer
Departments of Anaesthesiology, Ludwig Maximilians University, Munich, Germany
Crit Care Med 39:643-50. 2011.... 
Motion sickness, stress and the endocannabinoid systemAlexander Chouker
Department of Anesthesiology, Ludwig Maximilians University, Munich, Germany
PLoS ONE 5:e10752. 2010..The endocannabinoid system (ECS) represents an important neuromodulator of stress and N&V. Inhibitory effects of the ECS on N&V are mediated by endocannabinoid-receptor activation...- Complex interaction of sensory and motor signs and symptoms in chronic CRPSVolker Huge
Department of Anaesthesiology, Ludwig Maximilians Universitat Munchen, Munich, Germany
PLoS ONE 6:e18775. 2011.... - Efficacy of hydrocortisone in preventing posttraumatic stress disorder following critical illness and major surgeryGustav Schelling
Ludwig Maximilians University, Klinikum Grosshadern, Department of Anaesthesiology, 81377 Muenchen, Germany
Ann N Y Acad Sci 1071:46-53. 2006.... - Lymphocyte subsets and the role of TH1/TH2 balance in stressed chronic pain patientsInes Kaufmann
Department of Anesthesiology, Klinikum Grosshadern, Ludwig Maximilians University, Munich, Germany
Neuroimmunomodulation 14:272-80. 2007..Despite the known connection between the nervous system and immune cells, information on distribution of lymphocyte subsets under stress and pain conditions is limited... - Exposure to high stress in the intensive care unit may have negative effects on health-related quality-of-life outcomes after cardiac surgeryGustav Schelling
Department of Anesthesiology, Ludwig-Maximilians-University, Munich, Germany
Crit Care Med 31:1971-80. 2003..52, p <.01). CONCLUSIONS: Exposure to high stress in the cardiovascular intensive care unit can have negative effects on HRQL outcomes of cardiac surgery... - Adenosine A2(A) receptor modulates the oxidative stress response of primed polymorphonuclear leukocytes after parabolic flightInes Kaufmann
Department of Anaesthesiology, University of Munich, 81366 Munich, Germany
Hum Immunol 72:547-52. 2011..Pharmacologic manipulation of the adenosine A2(A) receptor pathway could be a potential target for control of unwanted exacerbations of cytotoxic PMN functions... - White and gray matter abnormalities in the brain of patients with fibromyalgia: a diffusion-tensor and volumetric imaging studyJürgen Lutz
Campus Grosshadern, Ludwig Maximilians University, Munich, Germany
Arthritis Rheum 58:3960-9. 2008.... - Substantially altered expression pattern of cannabinoid receptor 2 and activated endocannabinoid system in patients with severe heart failureFlorian Weis
Department of Anesthesiology, Ludwig Maximilians University, Munich, Germany
J Mol Cell Cardiol 48:1187-93. 2010..These results might open up new perspectives regarding the role of endocannabinoid signalling in CHF and its potential as a target for pharmacological modulation... - Can posttraumatic stress disorder be prevented with glucocorticoids?Gustav Schelling
Ludwig Maximilians University, Klinikum Grosshadern, Department of Anaesthesiology, 81377 Muenchen, Germany
Ann N Y Acad Sci 1032:158-66. 2004..Therefore, stress doses of hydrocortisone could be useful for prophylaxis and treatment of PTSD... - Psychoneuroendocrine stress response may impair neutrophil function in complex regional pain syndromeInes Kaufmann
Department of Anesthesiology, Klinikum Grosshadern, Ludwig Maximilians University, 81377, Munich, Germany
Clin Immunol 125:103-11. 2007..In conclusion, CRPS patients exhibit signs of impaired innate immunity which might reflect the immunological consequence of an immunosuppressive neuroendocrine stress response... - Breath isoprene concentrations in persons undergoing general anesthesia and in healthy volunteersCyrill Hornuss
Department of Anaesthesiology, Klinikum der Universitat Munchen, Munich, Germany
J Breath Res 6:046004. 2012..Rebreathing of isoprene from the anesthesia machine possibly accounts for the observed increase in isoprene in the anesthesia group... - Effect of stress doses of hydrocortisone on S-100B vs. interleukin-8 and polymorphonuclear elastase levels in human septic shockThomas Mussack
Department of Surgery Innenstadt, Klinikum der Universitat Munchen, Munich, Germany
Clin Chem Lab Med 43:259-68. 2005..For the first time, a similar extent of S-100B increase in serum of septic patients at the time of diagnosis was shown as reported for cardiac arrest or severe traumatic brain injury... - Propofol enhances memory formation via an interaction with the endocannabinoid systemDaniela Hauer
Department of Anaesthesiology, Ludwig Maximilians University, Munich, Germany
Anesthesiology 114:1380-8. 2011.... - [Psychiatric disorders in intensive care--part three: psychic reactions, affective and anxiety disorders]Till Krauseneck
Klinik fur Psychiatrie und Psychotherapie, Ludwig Maximilians Universitat Munchen, Munich, Germany
Anasthesiol Intensivmed Notfallmed Schmerzther 42:180-7. 2007.... - Indications and practical use of replacement dose of corticosteroids in critical illnessJosef Briegel
Department of Anaesthesiology, University Hospital, Ludwig Maximilians University, Munich, Germany
Curr Opin Crit Care 13:370-5. 2007..As the appropriate diagnosis of this clinical entity remains a challenge, indication and practical use of corticosteroid replacement therapy in the critically ill is generally directed by clinical symptoms and features... - Pitfalls in measuring the endocannabinoid 2-arachidonoyl glycerol in biological samplesMichael Vogeser
Institute of Clinical Chemistry, Hospital of the University of Munich, Munich, Germany
Clin Chem Lab Med 45:1023-5. 2007..The endocannabinoid 2-arachidonoyl glycerol (2-AG) undergoes spontaneous isomerization to biologically inactive 1-AG. This effect has not been adequately addressed in previous studies that reported 2-AG concentrations in biological samples... - Time course of expiratory propofol after bolus injection as measured by ion molecule reaction mass spectrometryCyrill Hornuss
Department of Anaesthesiology, Klinikum der Universitat, Ludwig Maximilians University Munich, Munich, Germany
Anal Bioanal Chem 403:555-61. 2012..This suggests that expiratory propofol concentrations may be useful for titrating intravenous anesthesia... - Real-time monitoring of propofol in expired air in humans undergoing total intravenous anesthesiaCyrill Hornuss
Department of Anesthesiology, Ludwig Maximilians University, Munich, Germany
Anesthesiology 106:665-74. 2007..This could allow real-time monitoring of relative changes in the propofol concentration in arterial blood during total intravenous anesthesia... - Release of anandamide from blood cellsMichael Vogeser
Institute of Clinical Chemistry, Hospital of the University of Munich, Munich, Germany
Clin Chem Lab Med 44:488-91. 2006..Since this might be caused by pre-analytical variables, we investigated the impact of different sample handling conditions on measured plasma anandamide concentrations... - Effects of low-dose intranasal (S)-ketamine in patients with neuropathic painVolker Huge
Department of Anaesthesiology, Ludwig Maximilians Universitat Munchen, Campus Grosshadern, Marchioninistrasse 15, 81377 Munich, Germany
Eur J Pain 14:387-94. 2010..NMDA receptors are involved in the development and maintenance of neuropathic pain. We evaluated the efficacy and safety of intranasal (S)-ketamine, one of the most potent clinically available NMDA receptor antagonists... - [Psychiatric emergencies on ICU]Till Krauseneck
Klinik für Psychiatrie und Psychotherapie der Ludwig Maximilians Universität München, Germany
Anasthesiol Intensivmed Notfallmed Schmerzther 42:10-3. 2007..Psychiatric emergencies are catatonia, stupor, central serotonine syndrome, malignant neuroleptic syndrome, suicide risk and agitation. In this article some clinical features of the aforementioned and its therapy are summarized... - [Psychiatric disorders in the ICU I: delirium]Till Krauseneck
Klinik fur Psychiatrie und Psychotherapie, Ludwig Maximilians Universitat Munchen, Germany
Anasthesiol Intensivmed Notfallmed Schmerzther 41:720-6. 2006..This article reviews the different forms of delirium, its causes and therapy strategies. Also changes of the ICU environment to prevent patients from delirium are mentioned... - Comparison of systemic and renal effects of dopexamine and dopamine in norepinephrine-treated septic shockMartin Schmoelz
Department of Anesthesiology, Ludwig Maximilians University, Munich, Germany
J Cardiothorac Vasc Anesth 20:173-8. 2006..The primary hypothesis to be tested was that dopexamine is more effective than dopamine and that dopamine shows better effects than placebo regarding organ failures and C(crea)... - Post-traumatic stress disorder in somatic disease: lessons from critically ill patientsGustav Schelling
Department of Anaesthesiology, Ludwig Maximilians University, 81377, Munich, Germany
Prog Brain Res 167:229-37. 2008..This could also result in new approaches for prophylaxis and treatment of stress-related disorders... - Effects of general anesthesia on anandamide blood levels in humansGustav Schelling
Department of Anaesthesiology, Institute for Medical Informatics, Ludwig-Maximilians University, Munich, Germany
Anesthesiology 104:273-7. 2006..These findings suggest new targets for anesthetic drug development... - Daptomycin, a lipopeptide antibiotic in clinical practiceFlorian Weis
Department of Anesthesiology, University Hospital Grosshader, Marchioninistrasse 15, 81377 Munich, Germany
Curr Opin Investig Drugs 9:879-84. 2008..The purpose of this article is to provide an overview of daptomycin, with particular emphasis on potential new indications for which it could be used in the future... - Psychiatric and psychosocial outcome of orthotopic liver transplantationHans Bernd Rothenhäusler
Department of Psychiatry, Ludwig Maximilians University of Munich, Munich, Germany
Psychother Psychosom 71:285-97. 2002..The study aimed to explore the prevalence of psychiatric disorders among orthotopic liver transplantation (OLT) recipients, and to investigate how psychiatric morbidity was linked to health-related quality of life (HRQOL)... - Glucocorticoids reduce phobic fear in humansLeila M Soravia
Institute of Psychology, Department of Clinical Psychology and Psychotherapy, , , , Switzerland
Proc Natl Acad Sci U S A 103:5585-90. 2006..Cortisol treatment did not reduce general, phobia-unrelated anxiety. In conclusion, the present findings in two distinct types of phobias indicate that glucocorticoid administration reduces phobic fear... - Posttraumatic stress disorder and health-related quality of life in long-term survivors of acute respiratory distress syndromeHans P Kapfhammer
Department of Psychiatry, Karl Franzens University, Graz, Austria
Am J Psychiatry 161:45-52. 2004..Psychiatric morbidity and negative effects on health-related quality of life were assessed in long-term survivors of acute respiratory distress syndrome... - Psychiatric and psychosocial outcome of cardiac surgery with cardiopulmonary bypass: a prospective 12-month follow-up studyHans Bernd Rothenhäusler
Department of Psychiatry, University of Medicine of Graz, A 8036 Graz, Austria
Gen Hosp Psychiatry 27:18-28. 2005.... - Low-dose cortisol for symptoms of posttraumatic stress disorderAmanda Aerni
Division of Psychiatry Research, University of Zurich, Lenggstr. 31, 8029 Zurich, Switzerland
Am J Psychiatry 161:1488-90. 2004..CONCLUSIONS: The results of this pilot study indicate that low-dose cortisol treatment reduces the cardinal symptoms of PTSD... - Corticotropin-releasing factor in the basolateral amygdala enhances memory consolidation via an interaction with the beta-adrenoceptor-cAMP pathway: dependence on glucocorticoid receptor activationBenno Roozendaal
Center for the Neurobiology of Learning and Memory, Department of Neurobiology and Behavior, University of California, Irvine, California 92697 3800, USA
J Neurosci 28:6642-51. 2008.... - A systemically administered beta-adrenoceptor antagonist blocks corticosterone-induced impairment of contextual memory retrieval in ratsBenno Roozendaal
Center for the Neurobiology of Learning and Memory, Department of Neurobiology and Behavior, University of California, Irvine, CA 92697 3800, USA
Neurobiol Learn Mem 81:150-4. 2004..These findings provide evidence for the view that glucocorticoids interact with noradrenergic mechanisms in influencing memory retrieval...