F Schaumburg


Affiliation: University Hospital
Country: Germany


  1. Schaumburg F, Sertic S, Correa Martinez C, Mellmann A, Kock R, Becker K. Acquisition and colonization dynamics of antimicrobial-resistant bacteria during international travel: a prospective cohort study. Clin Microbiol Infect. 2019;: pubmed publisher
    ..3, p 0.009) and CarbR-GN (OR = 0.3, p 0.01). VRE and C. difficile were not detected. The number of travellers with a temporary colonization during the journey exceeded the number of travellers still colonized after return. ..
  2. Schaumburg F, Peters G, Wardelmann E, Becker K, Sperveslage J. Evaluation of GenoType MTBDRplus by Use of Extracted DNA from Formalin-Fixed Paraffin-Embedded Specimens. J Clin Microbiol. 2017;55:3300-3302 pubmed publisher
  3. Ehrhardt J, Alabi A, Kuczius T, Tsombeng F, Becker K, Kremsner P, et al. Population structure of Legionella spp. from environmental samples in Gabon, 2013. Infect Genet Evol. 2015;33:299-303 pubmed publisher
    ..in the studied areas in Gabon, particularly if they have risk factors such as comorbidities. Both broadly extended (ST1, ST75) and local lineages (ST1911) were present in our setting. ..
  4. Schaumburg F, Alabi A, Kaba H, Lell B, Becker K, Grobusch M, et al. Molecular characterization of Shigella spp. from patients in Gabon 2011-2013. Trans R Soc Trop Med Hyg. 2015;109:275-9 pubmed publisher
    ..There is a strong link of Gabonese Shigella spp. isolates with pandemic lineages as they cluster with major global clones and frequently carry atypical class 1 integrons which are frequently reported in Shigella spp. from Asia. ..
  5. Alabi A, Kazimoto T, Lebughe M, Vubil D, Phaku P, Mandomando I, et al. Management of superficial and deep-seated Staphylococcus aureus skin and soft tissue infections in sub-Saharan Africa: a post hoc analysis of the StaphNet cohort. Infection. 2018;46:395-404 pubmed publisher
    ..Appropriate antimicrobial agents and surgical services to perform I&D were available for the majority of patients. Results from susceptibility testing should be considered more efficiently in the selection of antimicrobial therapy. ..
  6. Alabi A, Frielinghaus L, Kaba H, Kösters K, Huson M, Kahl B, et al. Retrospective analysis of antimicrobial resistance and bacterial spectrum of infection in Gabon, Central Africa. BMC Infect Dis. 2013;13:455 pubmed publisher
    ..The high diversity of potential pathogens and high resistance rates in Gram-negative bacteria challenge a rational empiric use of antibiotics. Countrywide continuous sentinel surveillance is therefore urgently needed. ..
  7. Onwugamba F, Fitzgerald J, Rochon K, Guardabassi L, Alabi A, Kühne S, et al. The role of 'filth flies' in the spread of antimicrobial resistance. Travel Med Infect Dis. 2018;22:8-17 pubmed publisher
    ..g. vectorial capacity, colonization dose). This requires targeted ecological, epidemiological and in vivo experimental studies. ..
  8. Schaumburg F, Pauly M, Anoh E, Mossoun A, Wiersma L, Schubert G, et al. Staphylococcus aureus complex from animals and humans in three remote African regions. Clin Microbiol Infect. 2015;21:345.e1-8 pubmed publisher
    ..However, such a transmission might remain possible due to the close phylogenetic relation of humans and nonhuman primates. The ST88-MRSA clone was widespread in Côte d'Ivoire but not in Gabon and DR Congo. ..
  9. Schaumburg F, Peters G, Alabi A, Becker K, Idelevich E. Missense mutations of PBP2a are associated with reduced susceptibility to ceftaroline and ceftobiprole in African MRSA. J Antimicrob Chemother. 2016;71:41-4 pubmed publisher
    ..9%) and ceftobiprole (81.8%). Resistances to ceftaroline and ceftobiprole were only detected in Nigeria and were associated with ST241 and a triple mutation of PBP2a. ..

More Information


  1. Phaku P, Lebughe M, Straus L, Peters G, Herrmann M, Mumba D, et al. Unveiling the molecular basis of antimicrobial resistance in Staphylococcus aureus from the Democratic Republic of the Congo using whole genome sequencing. Clin Microbiol Infect. 2016;22:644.e1-5 pubmed publisher
    ..Genotypic and phenotypical antimicrobial susceptibility testing showed high concordance. This encourages the future use of WGS in routine antimicrobial susceptibility testing. ..
  2. Ehrhardt J, Alabi A, Kremsner P, Rabsch W, Becker K, Foguim F, et al. Bacterial contamination of water samples in Gabon, 2013. J Microbiol Immunol Infect. 2017;50:718-722 pubmed publisher
    ..The main findings were a contamination rate with coliforms of 13.5% and the detection of a possible environmental reservoir for extended spectrum beta-lactamase-producing bacteria. ..
  3. Schaumburg F, Pauly M, Schubert G, Shittu A, Tong S, Leendertz F, et al. Characterization of a novel thermostable nuclease homolog (NucM) in a highly divergent Staphylococcus aureus clade. J Clin Microbiol. 2014;52:4036-8 pubmed publisher
    ..aureus. Its deduced amino acid sequences, tertiary structures, and nuclease activities, however, are similar. ..
  4. Schaumburg F, Onwugamba F, Akulenko R, Peters G, Mellmann A, Köck R, et al. A geospatial analysis of flies and the spread of antimicrobial resistant bacteria. Int J Med Microbiol. 2016;306:566-571 pubmed publisher
    ..In conclusion, flies can carry ESBL-E and LA-MRSA in urban and rural areas. The similar genetic background of isolates from humans and flies points towards a common source. ..
  5. Schaumburg F, Ngoa U, Kösters K, Kock R, Adegnika A, Kremsner P, et al. Virulence factors and genotypes of Staphylococcus aureus from infection and carriage in Gabon. Clin Microbiol Infect. 2011;17:1507-13 pubmed publisher
    ..aureus isolates from asymptomatic carriers and infections. Of note, S. aureus isolates from Gabon show a very high prevalence of PVL-encoding genes, which exceeds the rates observed for developed countries. ..
  6. Schaumburg F, Alabi A, von Eiff C, Flamen A, Traore H, Grobusch M, et al. Streptococcus pneumoniae colonization in remote African Pygmies. Trans R Soc Trop Med Hyg. 2013;107:105-9 pubmed publisher
    ..The unusual serotypes challenge a broad coverage by currently marketed vaccines; the broad antibiotic resistance limits the choice of therapy for S. pneumoniae infection. ..
  7. Schaumburg F, Biallas B, Ngoune Feugap E, Alabi A, Mordmuller B, Kremsner P, et al. Carriage of encapsulated bacteria in Gabonese children with sickle cell anaemia. Clin Microbiol Infect. 2013;19:235-41 pubmed publisher
    ..Our data provide the basis to guide empiric therapy of invasive diseases caused by S. pneumoniae, Staph. aureus and H. influenza in children in Gabon. ..
  8. Held J, Gmeiner M, Mordmuller B, Matsiegui P, Schaer J, Eckerle I, et al. Bats are rare reservoirs of Staphylococcus aureus complex in Gabon. Infect Genet Evol. 2017;47:118-120 pubmed publisher
    ..In conclusion, colonization rates of bats with S. aureus and S. schweitzeri were low in our study. Phylogenetic analysis supports an intense geographical dispersal of S. schweitzeri among different mammalian wildlife hosts. ..
  9. Schaumburg F, Kock R, Leendertz F, Becker K. Airport door handles and the global spread of antimicrobial-resistant bacteria: a cross sectional study. Clin Microbiol Infect. 2016;22:1010-1011 pubmed publisher
  10. Schaumburg F, Köck R, Friedrich A, Soulanoudjingar S, Ngoa U, von Eiff C, et al. Population structure of Staphylococcus aureus from remote African Babongo Pygmies. PLoS Negl Trop Dis. 2011;5:e1150 pubmed publisher
    ..Surveillance is needed to control the development of resistance to antibiotic drugs and to assess the impact of the high prevalence of PVL in indigenous populations. ..
  11. Schaumburg F, Biallas B, Alabi A, Grobusch M, Feugap E, Lell B, et al. Clonal structure of Staphylococcus aureus colonizing children with sickle cell anaemia and healthy controls. Epidemiol Infect. 2013;141:1717-20 pubmed publisher
  12. Schaumburg F, Alabi A, Frielinghaus L, Grobusch M, Köck R, Becker K, et al. The risk to import ESBL-producing Enterobacteriaceae and Staphylococcus aureus through chicken meat trade in Gabon. BMC Microbiol. 2014;14:286 pubmed publisher
    ..There is a risk to import ESBL E. coli to Gabon but molecular differences between isolates from humans and chicken meat argue against a further dissemination. No MRSA isolate was detected in imported chicken meat. ..
  13. Schaumburg F, Alabi A, Kokou C, Grobusch M, Köck R, Kaba H, et al. High burden of extended-spectrum ?-lactamase-producing Enterobacteriaceae in Gabon. J Antimicrob Chemother. 2013;68:2140-3 pubmed publisher
    ..The risk of nosocomial transmission of ESBL-E is a challenge in rural Africa and underlines the need for sentinel surveillance in the absence of a broad decentralized microbiology laboratory. ..