Research Topics
Species | Jürgen SchauberSummaryAffiliation: University of Munich Country: Germany Publications
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Detail Information
Publications
[Cathelicidin LL-37. A central factor in the pathogenesis of inflammatory dermatoses?]J Schauber
Klinik und Poliklinik fur Dermatologie und Allergologie, Ludwig Maximilians Universitat Munchen, Frauenlobstrasse 9 11, 80337 München
Hautarzt 59:72-4. 2008..These studies demonstrate the role of cathelicidin as a central factor in the pathogenesis of cutaneous inflammation. Therapies targeting cathelicidin expression and function could lead to new treatments for these diseases...
The vitamin D pathway: a new target for control of the skin's immune response?Jürgen Schauber
Department of Dermatology and Allergology, Ludwig Maximilians University, Munich, Germany
Exp Dermatol 17:633-9. 2008..Therapies targeting the vitamin D3 pathway and thereby cathelicidin may provide new treatment modalities in the management of infectious and inflammatory skin diseases...- [Topical therapy of perianal eczema]J Schauber
Klinik für Dermatologie und Allergologie, Ludwig Maximilians Universitat Munchen, Munchen, Deutschland
Hautarzt 61:33-8. 2010..Patients should avoid topical irritants and potential contact allergens. Perianal eczema resistant to therapy should be further evaluated by histopathological workup to exclude precancerous or malignant skin disease... - Control of cutaneous antimicrobial peptides by vitamin D3Yvonne Dombrowski
Department of Dermatology and Allergy, Klinik und Poliklinik fur Dermatologie und Allergologie, Ludwig Maximilian University, Frauenlobstr 9 11, Munich, Germany
Arch Dermatol Res 302:401-8. 2010..Therapies targeting vitamin D3 signaling may provide new approaches for infectious and inflammatory skin diseases by affecting both innate and adaptive immune functions... - [Antimicrobial peptides, Vitamin D₃ and more. How rosacea may develop]J Schauber
Klinik und Poliklinik fur Dermatologie und Allergologie, Ludwig Maximilians Universitat Munchen, Frauenlobstr 9 11, 80337 München
Hautarzt 62:815-9. 2011..These data increase our understanding of the pathogenesis and therapy of rosacea. Also, these insights might uncover novel targets for innovative therapies of this common, stigmatizing skin disease... - Topical treatment of perianal eczema with tacrolimus 0.1%J Schauber
Department of Dermatology, Ludwig Maximilians University, Munich, Germany
Br J Dermatol 161:1384-6. 2009..Topical calcineurin inhibitors such as tacrolimus (FK506) ameliorate cutaneous inflammation and associated pruritus in an array of inflammatory dermatoses... - VDR and MEK-ERK dependent induction of the antimicrobial peptide cathelicidin in keratinocytes by lithocholic acidMark Peric
Department of Dermatology and Allergy, Ludwig Maximilians University, Munich, Germany
Mol Immunol 46:3183-7. 2009..Based on these observations LCA-like molecules targeting cathelicidin could be designed for the treatment of cutaneous diseases that are characterized by disturbed cathelicidin expression... - Vitamin D analog calcipotriol suppresses the Th17 cytokine-induced proinflammatory S100 "alarmins" psoriasin (S100A7) and koebnerisin (S100A15) in psoriasisZuzana Hegyi
Department of Dermatology and Allergology, Ludwig Maximilian University, Munich, Germany
J Invest Dermatol 132:1416-24. 2012..Thus, targeting the S100-amplification loop could be a beneficial anti-inflammatory approach in psoriasis and other inflammatory skin diseases... - IL-17A enhances vitamin D3-induced expression of cathelicidin antimicrobial peptide in human keratinocytesMark Peric
Department of Dermatology and Allergology, Ludwig Maximilians University, Munich, Germany
J Immunol 181:8504-12. 2008..Therapy targeting this cathelicidin-regulating system might be beneficial in patients suffering from psoriasis... 
Antimicrobial peptides and the skin immune defense systemJürgen Schauber
Department of Dermatology and Allergology, Ludwig Maximilians University, Munich, Germany
J Allergy Clin Immunol 124:R13-8. 2009..Therapies targeting control of cathelicidin and other AMPs might provide new approaches in the management of infectious and inflammatory skin diseases...- Cathelicidin LL-37: a defense molecule with a potential role in psoriasis pathogenesisYvonne Dombrowski
Department of Dermatology and Allergy, Ludwig Maximilian University, Munich, Germany
Exp Dermatol 21:327-30. 2012..Hence, cathelicidin LL-37 shows contrasting roles in skin inflammation in psoriasis and might serve as a target for novel therapies for this chronic skin disease... - Innate immunity in atopic dermatitisAndreas Wollenberg
Department of Dermatology and Allergy, Ludwig Maximilian University of Munich, Germany
Clin Rev Allergy Immunol 41:272-81. 2011..Future therapeutic approaches to AD may include enhancement of impaired innate in addition to downregulation of dysfunctional adaptive immunity... - Vitamin D analogs differentially control antimicrobial peptide/"alarmin" expression in psoriasisMark Peric
Department of Dermatology and Allergology, Ludwig Maximilians University, Munich, Germany
PLoS ONE 4:e6340. 2009..Balancing AMP "alarmin" expression might be a novel goal in treatment of chronic inflammatory skin diseases... - Antimicrobial peptides and the skin immune defense systemJürgen Schauber
Department of Dermatology and Allergology, Ludwig Maximilians University, Munich, Germany
J Allergy Clin Immunol 122:261-6. 2008..Therapies targeting control of cathelicidin and other AMPs might provide new approaches in the management of infectious and inflammatory skin diseases... - Cathelicidin LL-37: an antimicrobial peptide with a role in inflammatory skin diseaseMarkus Reinholz
Department of Dermatology and Allergy, Ludwig Maximilian University, Munich, Germany
Ann Dermatol 24:126-35. 2012..As cathelicidin LL-37 might also serve as a future treatment target potential novel treatment strategies for those diseases will be discussed...