Matthias Schaier

Summary

Affiliation: University of Heidelberg
Country: Germany

Publications

  1. doi request reprint Role of FTY720 on M1 and M2 macrophages, lymphocytes, and chemokines in 5/6 nephrectomized rats
    Matthias Schaier
    Dept of Nephrology, Univ of Heidelberg, Im Neuenheimer Feld 162, 69120 Heidelberg, Germany
    Am J Physiol Renal Physiol 297:F769-80. 2009
  2. doi request reprint The extent of HLA-DR expression on HLA-DR(+) Tregs allows the identification of patients with clinically relevant borderline rejection
    Matthias Schaier
    Department of Nephrology, University of Heidelberg, D 69120 Heidelberg, Germany
    Transpl Int 26:290-9. 2013
  3. pmc DR(high+)CD45RA(-)-Tregs potentially affect the suppressive activity of the total Treg pool in renal transplant patients
    Matthias Schaier
    Department of Nephrology, University of Heidelberg, Heidelberg, Germany
    PLoS ONE 7:e34208. 2012
  4. ncbi request reprint Henoch-Schönlein purpura in adults is not uncommon in elderly patients with an adverse prognosis
    M Schaier
    Department of Nephrology, University of Heidelberg, Heidelberg, Germany
    Clin Nephrol 76:49-56. 2011
  5. doi request reprint Proton pump inhibitors interfere with the immunosuppressive potency of mycophenolate mofetil
    Matthias Schaier
    Department of Nephrology, University of Heidelberg, Heidelberg, Germany
    Rheumatology (Oxford) 49:2061-7. 2010
  6. ncbi request reprint Retinoic acid receptor alpha and retinoid X receptor specific agonists reduce renal injury in established chronic glomerulonephritis of the rat
    Matthias Schaier
    Department of Nephrology, University Hospital, University of Heidelberg, Bergheimer Strasse 56a, 69115, Heidelberg, Germany
    J Mol Med (Berl) 82:116-25. 2004
  7. doi request reprint Uremia aggravates left ventricular remodeling after myocardial infarction
    Ralf Dikow
    Department of Nephrology, University of Heidelberg, Heidelberg, Germany
    Am J Nephrol 32:13-22. 2010
  8. doi request reprint Chronic low-dose isotretinoin treatment limits renal damage in subtotally nephrectomized rats
    Christian Morath
    Department of Nephrology, University of Heidelberg, Im Neuenheimer Feld 162, 69120, Heidelberg, Germany
    J Mol Med (Berl) 87:53-64. 2009
  9. doi request reprint Methylprednisolone treatment increases the proportion of the highly suppressive HLA-DR(+)-Treg-cells in transplanted patients
    Nicole Seissler
    Department of Nephrology, University of Heidelberg, Germany
    Transpl Immunol 27:157-61. 2012
  10. pmc Pharmacokinetic and pharmacodynamic analysis of enteric-coated mycophenolate sodium: limited sampling strategies and clinical outcome in renal transplant patients
    Claudia Sommerer
    Department of Nephrology, University Hospital, Heidelberg, Germany
    Br J Clin Pharmacol 69:346-57. 2010

Collaborators

Detail Information

Publications16

  1. doi request reprint Role of FTY720 on M1 and M2 macrophages, lymphocytes, and chemokines in 5/6 nephrectomized rats
    Matthias Schaier
    Dept of Nephrology, Univ of Heidelberg, Im Neuenheimer Feld 162, 69120 Heidelberg, Germany
    Am J Physiol Renal Physiol 297:F769-80. 2009
    ..FTY720 significantly reduced key mediators of renal inflammation and fibrosis. FTY720 also decreased immunoregulation of M2 macrophages, which are beneficial for tissue remodeling and repair...
  2. doi request reprint The extent of HLA-DR expression on HLA-DR(+) Tregs allows the identification of patients with clinically relevant borderline rejection
    Matthias Schaier
    Department of Nephrology, University of Heidelberg, D 69120 Heidelberg, Germany
    Transpl Int 26:290-9. 2013
    ....
  3. pmc DR(high+)CD45RA(-)-Tregs potentially affect the suppressive activity of the total Treg pool in renal transplant patients
    Matthias Schaier
    Department of Nephrology, University of Heidelberg, Heidelberg, Germany
    PLoS ONE 7:e34208. 2012
    ..Therefore, both the monitoring of its percentage within the total Treg pool and the monitoring of the HLA-DR MFI of the DR(+)CD45RA(-)-Treg subset may be useful tools for the prediction of graft rejection...
  4. ncbi request reprint Henoch-Schönlein purpura in adults is not uncommon in elderly patients with an adverse prognosis
    M Schaier
    Department of Nephrology, University of Heidelberg, Heidelberg, Germany
    Clin Nephrol 76:49-56. 2011
    ..Henoch-Schönlein purpura (HSP) is a fairly common disease in children and adolescents. There are only limited data available for adults...
  5. doi request reprint Proton pump inhibitors interfere with the immunosuppressive potency of mycophenolate mofetil
    Matthias Schaier
    Department of Nephrology, University of Heidelberg, Heidelberg, Germany
    Rheumatology (Oxford) 49:2061-7. 2010
    ..Since PPIs are widely used, it is useful to clarify whether the total drug amount of MMF is available in patients undergoing PPI treatment...
  6. ncbi request reprint Retinoic acid receptor alpha and retinoid X receptor specific agonists reduce renal injury in established chronic glomerulonephritis of the rat
    Matthias Schaier
    Department of Nephrology, University Hospital, University of Heidelberg, Bergheimer Strasse 56a, 69115, Heidelberg, Germany
    J Mol Med (Berl) 82:116-25. 2004
    ..Receptor-specific retinoids may provide a novel therapeutic approach for the treatment of chronic glomerulonephritis...
  7. doi request reprint Uremia aggravates left ventricular remodeling after myocardial infarction
    Ralf Dikow
    Department of Nephrology, University of Heidelberg, Heidelberg, Germany
    Am J Nephrol 32:13-22. 2010
    ..Renal failure is a well-established cardiovascular risk factor. We hypothesized that uremia negatively affects post-myocardial infarction (MI) remodeling and left ventricular (LV) function and examined the pathohistological correlations...
  8. doi request reprint Chronic low-dose isotretinoin treatment limits renal damage in subtotally nephrectomized rats
    Christian Morath
    Department of Nephrology, University of Heidelberg, Im Neuenheimer Feld 162, 69120, Heidelberg, Germany
    J Mol Med (Berl) 87:53-64. 2009
    ..We conclude that LD isotretinoin attenuates progressive renal damage, whereas HD isotretinoin cumulates and aggravates renal damage independent of blood pressure reduction...
  9. doi request reprint Methylprednisolone treatment increases the proportion of the highly suppressive HLA-DR(+)-Treg-cells in transplanted patients
    Nicole Seissler
    Department of Nephrology, University of Heidelberg, Germany
    Transpl Immunol 27:157-61. 2012
    ....
  10. pmc Pharmacokinetic and pharmacodynamic analysis of enteric-coated mycophenolate sodium: limited sampling strategies and clinical outcome in renal transplant patients
    Claudia Sommerer
    Department of Nephrology, University Hospital, Heidelberg, Germany
    Br J Clin Pharmacol 69:346-57. 2010
    ..Pharmacokinetic (PK) and pharmacodynamic (PD) monitoring strategies and clinical outcome were evaluated in enteric-coated mycophenolate sodium (EC-MPS)-treated renal allograft recipients...
  11. doi request reprint Cellular infiltrates and NFκB subunit c-Rel signaling in kidney allografts of patients with clinical operational tolerance
    Luis E Becker
    Division of Nephrology, Department of Medicine, University of Heidelberg, Heidelberg, Germany
    Transplantation 94:729-37. 2012
    ....
  12. doi request reprint In renal transplants with delayed graft function chemokines and chemokine receptor expression predict long-term allograft function
    Ralf Dikow
    Department of Nephrology, University of Heidelberg, INF Heidelberg, Germany
    Transplantation 90:771-6. 2010
    ..We studied the role of chemokines in kidney allografts with delayed graft function and the subsequent long-term outcome of renal function and fibrosis...
  13. doi request reprint A distinct subset of HLA-DR+-regulatory T cells is involved in the induction of preterm labor during pregnancy and in the induction of organ rejection after transplantation
    Anna Kisielewicz
    Department of Obstetrics and Gynecology, University of Heidelberg, Voss Strasse 9, 69115 Heidelberg, Germany
    Clin Immunol 137:209-20. 2010
    ....
  14. doi request reprint Effect of insulin and glucose infusion on myocardial infarction size in uraemic rats
    Ralf Dikow
    Department of Nephrology, University Hospital of Heidelberg, Heidelberg, Germany
    Basic Res Cardiol 104:571-9. 2009
    ..Further analysis did not reveal a down regulation in GLUT 4 and IRS-1/IRS-2...
  15. ncbi request reprint Retinoid agonist isotretinoin ameliorates obstructive renal injury
    Matthias Schaier
    Department of Nephrology, University Hospital Heidelberg, Germany
    J Urol 170:1398-402. 2003
    ..Therefore, we studied the dose dependent effects of the retinoid receptor agonist isotretinoin 13-cis retinoic acid in the unilateral ureteral obstruction model (UUO)...
  16. ncbi request reprint Retinoid receptor-specific agonists alleviate experimental glomerulonephritis
    Ingo Lehrke
    Department of Nephrology, University of Heidelberg, 69120 Heidelberg, Germany
    Am J Physiol Renal Physiol 282:F741-51. 2002
    ..Further studies are indicated to define the potential use of retinoid agonists in inflammatory renal disease...