A S Schaefer

Summary

Affiliation: University of Kiel
Country: Germany

Publications

  1. doi Validation of reported genetic risk factors for periodontitis in a large-scale replication study
    Arne S Schaefer
    Institute for Clinical Molecular Biology, Christian Albrechts University, Kiel, Germany
    J Clin Periodontol 40:563-72. 2013
  2. pmc Role of NOD2/CARD15 in coronary heart disease
    Nour Eddine El Mokhtari
    Department of Cardiology, University Hospital Schleswig Holstein, Kiel, Germany
    BMC Genet 8:76. 2007
  3. pmc Identification of a shared genetic susceptibility locus for coronary heart disease and periodontitis
    Arne S Schaefer
    Institute for Clinical Molecular Biology, University Medical Center Schleswig Holstein, Kiel, Germany
    PLoS Genet 5:e1000378. 2009
  4. doi A 3' UTR transition within DEFB1 is associated with chronic and aggressive periodontitis
    A S Schaefer
    Institute for Clinical Molecular Biology, University Medical Center Schleswig Holstein, Kiel, Germany
    Genes Immun 11:45-54. 2010
  5. doi A genome-wide association study identifies GLT6D1 as a susceptibility locus for periodontitis
    Arne S Schaefer
    Institute for Clinical Molecular Biology, Christian Albrechts University Kiel, Schittenhelmstrasse 12, Kiel, Germany
    Hum Mol Genet 19:553-62. 2010
  6. doi COX-2 is associated with periodontitis in Europeans
    A S Schaefer
    Christian Albrechts University, Institute for Clinical Molecular Biology, Schittenhelmstrasse 12, 24105 Kiel, Germany
    J Dent Res 89:384-8. 2010
  7. doi CDKN2BAS is associated with periodontitis in different European populations and is activated by bacterial infection
    Arne S Schaefer
    Christian Albrechts University Kiel, Institute for Clinical Molecular Biology, Kiel, Germany
    J Med Genet 48:38-47. 2011

Detail Information

Publications7

  1. doi Validation of reported genetic risk factors for periodontitis in a large-scale replication study
    Arne S Schaefer
    Institute for Clinical Molecular Biology, Christian Albrechts University, Kiel, Germany
    J Clin Periodontol 40:563-72. 2013
    ..Many studies investigated the role of genetic variants in periodontitis, but few were established as risk factors. We aimed to validate the associations of recent candidate genes in aggressive periodontitis (AgP)...
  2. pmc Role of NOD2/CARD15 in coronary heart disease
    Nour Eddine El Mokhtari
    Department of Cardiology, University Hospital Schleswig Holstein, Kiel, Germany
    BMC Genet 8:76. 2007
    ....
  3. pmc Identification of a shared genetic susceptibility locus for coronary heart disease and periodontitis
    Arne S Schaefer
    Institute for Clinical Molecular Biology, University Medical Center Schleswig Holstein, Kiel, Germany
    PLoS Genet 5:e1000378. 2009
    ....
  4. doi A 3' UTR transition within DEFB1 is associated with chronic and aggressive periodontitis
    A S Schaefer
    Institute for Clinical Molecular Biology, University Medical Center Schleswig Holstein, Kiel, Germany
    Genes Immun 11:45-54. 2010
    ..Prediction of microRNA targets identified a potential microRNA-binding site at the position of rs1047031...
  5. doi A genome-wide association study identifies GLT6D1 as a susceptibility locus for periodontitis
    Arne S Schaefer
    Institute for Clinical Molecular Biology, Christian Albrechts University Kiel, Schittenhelmstrasse 12, Kiel, Germany
    Hum Mol Genet 19:553-62. 2010
    ..The identified association of GLT6D1 with AgP implicates this locus as an important susceptibility factor, and GATA-3 as a potential signaling component in the pathophysiology of periodontitis...
  6. doi COX-2 is associated with periodontitis in Europeans
    A S Schaefer
    Christian Albrechts University, Institute for Clinical Molecular Biology, Schittenhelmstrasse 12, 24105 Kiel, Germany
    J Dent Res 89:384-8. 2010
    ..57 (95% confidence interval 1.18-2.08; p = 0.002). The validation of the association of rs20417 by the htSNP rs6681231 provides evidence for a general genetic risk of COX-2 variants in the pathogenesis of periodontitis...
  7. doi CDKN2BAS is associated with periodontitis in different European populations and is activated by bacterial infection
    Arne S Schaefer
    Christian Albrechts University Kiel, Institute for Clinical Molecular Biology, Kiel, Germany
    J Med Genet 48:38-47. 2011
    ..003) and GECs (p=0.004), respectively. Considering the global importance of CDKN2BAS in the disease risk of CHD, this observation supports the theory of inflammatory components in the disease physiology of CHD...