Georg Sauer

Summary

Affiliation: University of Ulm
Country: Germany

Publications

  1. ncbi Polymorphism C3435T of the MDR-1 gene predicts response to preoperative chemotherapy in locally advanced breast cancer
    Ariane Kafka
    Department of Obstetrics and Gynecology, University of Ulm Medical School, Ulm, Germany
    Int J Oncol 22:1117-21. 2003
  2. ncbi New molecular targets of breast cancer therapy
    Georg Sauer
    Department of Gynecology and Obstetrics, University of Ulm Medical School, Ulm, Germany
    Strahlenther Onkol 178:123-33. 2002
  3. ncbi Immunotherapy and cancer vaccines in the management of breast cancer
    Georg Sauer
    Department of Gynaecology and Obstetrics, University of Ulm Medical School, Ulm, Germany
    Curr Pharm Des 11:3475-83. 2005
  4. ncbi Partial breast irradiation after breast-conserving surgery
    Georg Sauer
    Department of Gynecology, University of Ulm, Germany
    Strahlenther Onkol 181:1-8. 2005
  5. ncbi Ultrasound-guided large-core needle biopsies of breast lesions: analysis of 962 cases to determine the number of samples for reliable tumour classification
    G Sauer
    Department of Obstetrics and Gynecology, University of Ulm Medical School, Prittwitzstr 43, Ulm 89075, Germany
    Br J Cancer 92:231-5. 2005
  6. ncbi Angiogenesis: prognostic and therapeutic implications in gynecologic and breast malignancies
    Georg Sauer
    Department of Gynecology and Obstetrics, University of Ulm Medical School, Germany
    Curr Opin Obstet Gynecol 15:45-9. 2003
  7. ncbi Molecular indicators of non-sentinel node status in breast cancer determined in preoperative biopsies by multiplexed sandwich immunoassays
    Georg Sauer
    Department of Obstetrics and Gynaecology, University of Ulm, Prittwitzstr 43, 89075 Ulm, Germany
    J Cancer Res Clin Oncol 137:1175-84. 2011
  8. ncbi Chemotherapeutic agents enhance AAV2-mediated gene transfer into breast cancer cells promoting CD40 ligand-based immunotherapy
    Bernd Koppold
    Department of Obstetrics and Gynecology, University of Ulm Medical School, Frauensteige 14, 89075, Ulm, Germany
    J Cancer Res Clin Oncol 132:787-94. 2006
  9. ncbi CD9 promotes adeno-associated virus type 2 infection of mammary carcinoma cells with low cell surface expression of heparan sulphate proteoglycans
    Christian Kurzeder
    Department of Obstetrics and Gynaecology, University of Ulm Medical School, Frauensteige 14, D 89075 Ulm, Germany
    Int J Mol Med 19:325-33. 2007
  10. ncbi Expression of tetraspanin adaptor proteins below defined threshold values is associated with in vitro invasiveness of mammary carcinoma cells
    Georg Sauer
    Department of Obstetrics and Gynecology, University of Ulm Medical School, Ulm, Germany
    Oncol Rep 10:405-10. 2003

Collaborators

Detail Information

Publications19

  1. ncbi Polymorphism C3435T of the MDR-1 gene predicts response to preoperative chemotherapy in locally advanced breast cancer
    Ariane Kafka
    Department of Obstetrics and Gynecology, University of Ulm Medical School, Ulm, Germany
    Int J Oncol 22:1117-21. 2003
    ..029) between clinical complete response to preoperative chemotherapy and the T/T genotype. MDR-1 polymorphism C3435T in exon 26 may co-determine resistance to chemotherapy and provide useful information to individualize therapy...
  2. ncbi New molecular targets of breast cancer therapy
    Georg Sauer
    Department of Gynecology and Obstetrics, University of Ulm Medical School, Ulm, Germany
    Strahlenther Onkol 178:123-33. 2002
    ..Promising strategies include inhibition of growth factor receptors, blocking of tumor angiogenesis and signal transduction pathways, modulation of apoptosis, cancer vaccination, and inhibition of invasion and metastasis...
  3. ncbi Immunotherapy and cancer vaccines in the management of breast cancer
    Georg Sauer
    Department of Gynaecology and Obstetrics, University of Ulm Medical School, Ulm, Germany
    Curr Pharm Des 11:3475-83. 2005
    ....
  4. ncbi Partial breast irradiation after breast-conserving surgery
    Georg Sauer
    Department of Gynecology, University of Ulm, Germany
    Strahlenther Onkol 181:1-8. 2005
    ..Since the majority of local recurrences in selected patients occur close to the former tumor bed, the question arises whether a sole tumor bed irradiation might be a therapeutic alternative to total breast irradiation...
  5. ncbi Ultrasound-guided large-core needle biopsies of breast lesions: analysis of 962 cases to determine the number of samples for reliable tumour classification
    G Sauer
    Department of Obstetrics and Gynecology, University of Ulm Medical School, Prittwitzstr 43, Ulm 89075, Germany
    Br J Cancer 92:231-5. 2005
    ....
  6. ncbi Angiogenesis: prognostic and therapeutic implications in gynecologic and breast malignancies
    Georg Sauer
    Department of Gynecology and Obstetrics, University of Ulm Medical School, Germany
    Curr Opin Obstet Gynecol 15:45-9. 2003
    ..Summarizing the results of very recent studies, we discuss the clinical relevance of vascularization of breast and gynecological tumors...
  7. ncbi Molecular indicators of non-sentinel node status in breast cancer determined in preoperative biopsies by multiplexed sandwich immunoassays
    Georg Sauer
    Department of Obstetrics and Gynaecology, University of Ulm, Prittwitzstr 43, 89075 Ulm, Germany
    J Cancer Res Clin Oncol 137:1175-84. 2011
    ....
  8. ncbi Chemotherapeutic agents enhance AAV2-mediated gene transfer into breast cancer cells promoting CD40 ligand-based immunotherapy
    Bernd Koppold
    Department of Obstetrics and Gynecology, University of Ulm Medical School, Frauensteige 14, 89075, Ulm, Germany
    J Cancer Res Clin Oncol 132:787-94. 2006
    ..We also confirmed that breast cancer cells can activate human dendritic cells after infection with a CD40L-encoding rAAV...
  9. ncbi CD9 promotes adeno-associated virus type 2 infection of mammary carcinoma cells with low cell surface expression of heparan sulphate proteoglycans
    Christian Kurzeder
    Department of Obstetrics and Gynaecology, University of Ulm Medical School, Frauensteige 14, D 89075 Ulm, Germany
    Int J Mol Med 19:325-33. 2007
    ....
  10. ncbi Expression of tetraspanin adaptor proteins below defined threshold values is associated with in vitro invasiveness of mammary carcinoma cells
    Georg Sauer
    Department of Obstetrics and Gynecology, University of Ulm Medical School, Ulm, Germany
    Oncol Rep 10:405-10. 2003
    ....
  11. ncbi Progression of cervical carcinomas is associated with down-regulation of CD9 but strong local re-expression at sites of transendothelial invasion
    Georg Sauer
    Department of Obstetrics and Gynecology, University of Ulm Medical School, Ulm, Germany
    Clin Cancer Res 9:6426-31. 2003
    ....
  12. ncbi Spectrum of p53 mutations in biopsies from breast cancer patients selected for preoperative chemotherapy analysed by the functional yeast assay to predict therapeutic response
    Helmut Deissler
    Department of Obstetrics and Gynecology, University of Ulm Medical School, D 89075 Ulm, Germany
    Oncol Rep 11:1281-6. 2004
    ....
  13. ncbi Stage IB endometrial cancer. Does lymphadenectomy replace adjuvant radiotherapy?
    Dirk Bottke
    Department of Radiotherapy and Radiation Oncology, University Hospital, Ulm, Germany
    Strahlenther Onkol 183:600-4. 2007
    ..The aim of this review is to rule out the validity of either treatment option and determine which preference provides the best therapeutic benefit...
  14. ncbi Efficient gene transfer of CD40 ligand into ovarian carcinoma cells with a recombinant adeno-associated virus vector
    Bernd Koppold
    University of Ulm Medical School, Department of Obstetrics and Gynecology, Ulm, Germany
    Int J Oncol 26:95-101. 2005
    ....
  15. ncbi Prediction of nodal involvement in breast cancer based on multiparametric protein analyses from preoperative core needle biopsies of the primary lesion
    Georg Sauer
    Department of Obstetrics and Gynaecology, University of Ulm, Germany
    Clin Cancer Res 14:3345-53. 2008
    ..In this first study of such type, we therefore investigated the potential of multiplexed sandwich immunoassays to define protein expression profiles indicative of clinically relevant properties of malignant tumors...
  16. ncbi Glycosylation of tetraspanin Tspan-1 at four distinct sites promotes its transition through the endoplasmic reticulum
    Claus Jürgen Scholz
    Department of Obstetrics and Gynaecology, University of Ulm, Germany
    Protein Pept Lett 16:1244-8. 2009
    ..Glycosylation seemed to be required for correct folding and subsequent transition through the endoplasmic reticulum...
  17. ncbi Molecular targets of ovarian carcinomas with acquired resistance to platinum/taxane chemotherapy
    Christian Kurzeder
    University of Ulm Medical School, Department of Obstetrics and Gynaecology, Germany
    Curr Cancer Drug Targets 6:207-27. 2006
    ....
  18. ncbi Increased radiosensitivity as an indicator of genes conferring breast cancer susceptibility
    Dominic Varga
    Department of Gynecology and Obstetrics, University of Ulm Medical School, Ulm, Germany
    Strahlenther Onkol 183:655-60. 2007
    ....
  19. ncbi Basal expression of the multidrug resistance gene 1 (MDR-1) is associated with the TT genotype at the polymorphic site C3435T in mammary and ovarian carcinoma cell lines
    Georg Sauer
    Department of Obstretrics and Gynecology, University of Ulm Medical School, Frauensteige 14, D-89075, Ulm, Germany
    Cancer Lett 185:79-85. 2002
    ..0448, Fisher's exact test) with the TT genotype at position 3435 of the MDR-1 gene...