Research Topics
Genomes and GenesSpecies | E RyschichSummaryAffiliation: University of Heidelberg Country: Germany Publications
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Detail Information
Publications
Blockade of leukocyte haptokinesis and haptotaxis by ketoprofen, diclofenac and SC-560Saulius Paskauskas
Department of Surgery, University of Heidelberg, Germany
BMC Immunol 12:64. 2011..Using time-lapse microscopy and 96-well fluorescence-based assay, we studied the effect of three different NSAID, ketoprofen, diclofenac and SC-560, on leukocyte haptokinesis and haptotaxis in vivo and in vitro...
Promotion of tumor cell migration by extracellular matrix proteins in human pancreatic cancerEduard Ryschich
Department of Surgery, University of Heidelberg, Germany
Pancreas 38:804-10. 2009..The correlation between the aberrant expression of basement membrane proteins and the process of tumor invasion and metastasis has not been fully determined...
Intracapillary leucocyte accumulation as a novel antihaemorrhagic mechanism in acute pancreatitis in miceE Ryschich
Department of Surgery, Im Neuenheimer Feld 110, University of Heidelberg, Heidelberg 69120, Germany
Gut 58:1508-16. 2009..Although leucocytes play an active role in the pathophysiology of this disease, the relation between leucocyte activation, microvascular injury and haemorrhage has not been adequately addressed...
Loss of heterozygosity in the HLA class I region in human pancreatic cancerE Ryschich
Department of Surgery, University of Heidelberg, Heidelberg, Germany
Tissue Antigens 64:696-702. 2004..In conclusion, LOH does not seem to be the only factor for the reduced expression of HLA class I antigen as well as for the T-cell infiltration in this type of tumor...
Transfection with CD40L induces tumour suppression by dendritic cell activation in an orthotopic mouse model of pancreatic adenocarcinomaS Serba
Department of Surgery, University of Heidelberg, Heidelberg, Germany
Gut 57:344-51. 2008..Therefore, immunotherapeutic approaches might be considered promising and have gained importance over the last few years. In this study, CD40L gene transfer was tested as potent immunotherapy...
Effect of Flt3 ligand gene transfer in experimental pancreatic cancerE Ryschich
Dept of Surgery, University of Heidelberg, Im Neuenheimer Feld 110, 69120 Heidelberg, Germany
Int J Colorectal Dis 22:215-23. 2007..This mechanism is currently being evaluated in the therapy of malignant tumors. The aim of the present study was to study the effect of FL gene transfer on the immune response and tumor growth in experimental pancreatic cancer...
Taurine protects from liver injury after warm ischemia in rats: the role of kupffer cellsM Kincius
Department of General Surgery, Ruprecht Karls University, Heidelberg, Germany
Eur Surg Res 39:275-83. 2007..Taurine prevents Kupffer cell activation and improves graft survival after experimental cold ischemia and liver transplantation. Thus this study was designed to assess its effects after warm hepatic ischemia...
Transferrin receptor is a marker of malignant phenotype in human pancreatic cancer and in neuroendocrine carcinoma of the pancreasE Ryschich
Department of Surgery, University of Heidelberg, Im Neuenheimer Feld 110, 69120 Heidelberg, Germany
Eur J Cancer 40:1418-22. 2004..Hence, TFRC represents a marker of malignant transformation in the pancreas that could be applied as potential diagnostic and therapeutic target...
In vivo assessment of angioarchitecture and microcirculation in experimental liver cancer: a new model in ratsS M Maksan
Department of Surgery, University of Heidelberg, Heidelberg, Germany
Dig Dis Sci 48:279-90. 2003..The model represents a useful experimental tool to explore angiogenesis inhibition or immunological therapeutic strategies in experimental liver cancer...
Chronic alcohol intake increases the severity of pancreatitis induced by acute alcohol administration, hyperlipidemia and pancreatic duct obstruction in ratsJ Grauvogel
Department of Surgery, University of Heidelberg, Heidelberg, Germany
Pancreatology 10:603-12. 2010..It is of special interest why only about 5% of all alcoholics develop an episode of pancreatitis. We evaluated the role of long-term alcohol intake in the pathogenesis of alcoholic pancreatitis in rats...
Improved lentiviral transduction of human mesenchymal stem cells for therapeutic intervention in pancreatic cancerG Kallifatidis
Molecular OncoSurgery, University of Heidelberg and German Cancer Research Center, Heidelberg, Germany
Cancer Gene Ther 15:231-40. 2008..Together, LV transduction of genes to MSC followed by puromycin selection is a powerful tool for basic research and improves the therapeutic prospects of MSC as vehicles in gene therapy...
Expression of HLA class I/II antigens and T cell immune response in human neuroendocrine tumors of the pancreasE Ryschich
Department of Surgery, Department of Pathology, University of Heidelberg, Germany
Tissue Antigens 62:48-54. 2003..In contrast to malignant tumors of the exocrine pancreas, expression of HLA class II was absent in neuendocrine pancreatic tumor cells...
Angiogenesis inhibition with TNP-470, 2-methoxyestradiol, and paclitaxel in experimental pancreatic carcinomaE Ryschich
Department of Surgery, University of Heidelberg, Heidelberg, Germany
Pancreas 26:166-72. 2003..The combination of different angiogenesis inhibitors or higher doses might be more effective...
