Petra Ruemmele

Summary

Affiliation: University of Regensburg
Country: Germany

Publications

  1. pmc RNOP-09: pegylated liposomal doxorubicine and prolonged temozolomide in addition to radiotherapy in newly diagnosed glioblastoma--a phase II study
    Christoph P Beier
    Department of Neurology, University of Regensburg, Universitatsstrasse 84, 93053 Regensburg, Germany
    BMC Cancer 9:308. 2009
  2. doi request reprint Histopathologic features and microsatellite instability of cancers of the papilla of vater and their precursor lesions
    Petra Ruemmele
    Institute of Pathology, University of Regensburg, Regensburg, Germany
    Am J Surg Pathol 33:691-704. 2009
  3. doi request reprint Secondary sclerosing cholangitis
    Petra Ruemmele
    Department of Internal Medicine I, University of Regensburg, Germany
    Nat Rev Gastroenterol Hepatol 6:287-95. 2009
  4. ncbi request reprint Strong expression of methylthioadenosine phosphorylase (MTAP) in human colon carcinoma cells is regulated by TCF1/[beta]-catenin
    Frauke Bataille
    Institute of Pathology, University of Regensburg Medical School, Regensburg, Germany
    Lab Invest 85:124-36. 2005
  5. doi request reprint MethyQESD, a robust and fast method for quantitative methylation analyses in HNPCC diagnostics using formalin-fixed and paraffin-embedded tissue samples
    Marcus Bettstetter
    Institute of Pathology and Molecular Diagnostics, University of Regensburg, Regensburg, Germany
    Lab Invest 88:1367-75. 2008
  6. ncbi request reprint Distinction of hereditary nonpolyposis colorectal cancer and sporadic microsatellite-unstable colorectal cancer through quantification of MLH1 methylation by real-time PCR
    Marcus Bettstetter
    Institute of Pathology and Molecular Diagnostics, University of Regensburg, Regensburg, Germany
    Clin Cancer Res 13:3221-8. 2007
  7. doi request reprint Mismatch repair proteins hMLH1 and hMSH2 are differently expressed in the three main subtypes of sporadic renal cell carcinoma
    Christine Stoehr
    Institute of Pathology, University of Erlangen, Erlangen, Germany
    Pathobiology 79:162-8. 2012
  8. ncbi request reprint Gene expression profiling of colorectal cancer and metastases divides tumours according to their clinicopathological stage
    Astrid Koehler
    Department of Pathology, University of Regensburg, Germany
    J Pathol 204:65-74. 2004
  9. doi request reprint Bile duct damage after cold storage of deceased donor livers predicts biliary complications after liver transplantation
    Stefan M Brunner
    Department of Surgery, University Medical Center Regensburg, Regensburg, Germany
    J Hepatol 58:1133-9. 2013
  10. pmc STAT5b as molecular target in pancreatic cancer--inhibition of tumor growth, angiogenesis, and metastases
    Christian Moser
    Department of Surgery, University of Regensburg Medical Center, Regensburg, Germany
    Neoplasia 14:915-25. 2012

Collaborators

Detail Information

Publications15

  1. pmc RNOP-09: pegylated liposomal doxorubicine and prolonged temozolomide in addition to radiotherapy in newly diagnosed glioblastoma--a phase II study
    Christoph P Beier
    Department of Neurology, University of Regensburg, Universitatsstrasse 84, 93053 Regensburg, Germany
    BMC Cancer 9:308. 2009
    ..Although Temozolomide is effective against glioblastoma, the prognosis remains dismal and new regimens with synergistic activity are sought for...
  2. doi request reprint Histopathologic features and microsatellite instability of cancers of the papilla of vater and their precursor lesions
    Petra Ruemmele
    Institute of Pathology, University of Regensburg, Regensburg, Germany
    Am J Surg Pathol 33:691-704. 2009
    ..The MMR deficient molecular pathway of carcinogenesis is associated with a histopathologic phenotype in ampullary cancer, similar to the one that has been well described in colon cancer...
  3. doi request reprint Secondary sclerosing cholangitis
    Petra Ruemmele
    Department of Internal Medicine I, University of Regensburg, Germany
    Nat Rev Gastroenterol Hepatol 6:287-95. 2009
    ..Sclerosing cholangitis in critically ill patients, in particular, is associated with rapid disease progression and poor outcome...
  4. ncbi request reprint Strong expression of methylthioadenosine phosphorylase (MTAP) in human colon carcinoma cells is regulated by TCF1/[beta]-catenin
    Frauke Bataille
    Institute of Pathology, University of Regensburg Medical School, Regensburg, Germany
    Lab Invest 85:124-36. 2005
    ..This finding may be of clinical significance concerning the homeostasis of normal colon epithelium and potential treatment of colon carcinoma...
  5. doi request reprint MethyQESD, a robust and fast method for quantitative methylation analyses in HNPCC diagnostics using formalin-fixed and paraffin-embedded tissue samples
    Marcus Bettstetter
    Institute of Pathology and Molecular Diagnostics, University of Regensburg, Regensburg, Germany
    Lab Invest 88:1367-75. 2008
    ..Furthermore, MethyQESD works reliably with formalin-fixed paraffin-embedded tissue and simplifies DNA MA both for research and diagnostic purposes...
  6. ncbi request reprint Distinction of hereditary nonpolyposis colorectal cancer and sporadic microsatellite-unstable colorectal cancer through quantification of MLH1 methylation by real-time PCR
    Marcus Bettstetter
    Institute of Pathology and Molecular Diagnostics, University of Regensburg, Regensburg, Germany
    Clin Cancer Res 13:3221-8. 2007
    ..The aim of this study is to establish a reliable and quantitative MLH1 methylation analysis technique and to define valid MLH1 methylation cutoff values for HNPCC diagnostics...
  7. doi request reprint Mismatch repair proteins hMLH1 and hMSH2 are differently expressed in the three main subtypes of sporadic renal cell carcinoma
    Christine Stoehr
    Institute of Pathology, University of Erlangen, Erlangen, Germany
    Pathobiology 79:162-8. 2012
    ..We studied the role of minor mismatch repair proteins (MMR) human MutL homologue 1 (hMLH1) and human MutS homologue 2 (hMSH2) in the main subtypes of renal cell carcinoma (RCC)...
  8. ncbi request reprint Gene expression profiling of colorectal cancer and metastases divides tumours according to their clinicopathological stage
    Astrid Koehler
    Department of Pathology, University of Regensburg, Germany
    J Pathol 204:65-74. 2004
    ..These genes may represent important targets in colorectal carcinogenesis and might provide useful clinicopathological tools in the management of colorectal cancer...
  9. doi request reprint Bile duct damage after cold storage of deceased donor livers predicts biliary complications after liver transplantation
    Stefan M Brunner
    Department of Surgery, University Medical Center Regensburg, Regensburg, Germany
    J Hepatol 58:1133-9. 2013
    ..The aim of this study was to examine the development of biliary epithelial damage between organ retrieval and transplantation and its clinical relevance for patients...
  10. pmc STAT5b as molecular target in pancreatic cancer--inhibition of tumor growth, angiogenesis, and metastases
    Christian Moser
    Department of Surgery, University of Regensburg Medical Center, Regensburg, Germany
    Neoplasia 14:915-25. 2012
    ..Taken together, our results suggest that STAT5b might be a potential novel target for human DPAC...
  11. doi request reprint Lack of evidence for frequent MED12 p.L1224F mutation in prostate tumours from Caucasian patients
    Robert Stoehr
    Institute of Pathology, University Hospital Erlangen, 91054, Erlangen, Germany
    J Pathol 230:453-6. 2013
    ..Contrary to the findings of Barbieri et al, our data indicate either that the p.L1224F mutation in the MED12 gene plays no role in prostate carcinogenesis or that this alteration is only relevant in a small subgroup of tumours...
  12. doi request reprint Causes of bolus impaction in the esophagus
    Gabriele I Kirchner
    Department of Internal Medicine I, University Hospital of Regensburg, Regensburg, Germany
    Surg Endosc 25:3170-4. 2011
    ..Bolus impaction in the esophagus is a common indication for emergency endoscopy. The aim of this study was to determine the most common causes of esophageal bolus impaction...
  13. doi request reprint Manganese superoxide dismutase is reduced in the liver of male but not female humans and rodents with non-alcoholic fatty liver disease
    Sabrina Krautbauer
    Department of Internal Medicine I, Regensburg University Hospital, 93042 Regensburg, Germany
    Exp Mol Pathol 95:330-5. 2013
    ..Adiponectin which attenuates oxidative stress partly by increasing MnSOD in macrophages does not induce MnSOD in PHH. In summary, current data show that hepatic MnSOD is reduced in male but not female humans and rodents with NAFLD. ..
  14. doi request reprint Mdm2 SNP309 G-variant is associated with invasive growth of human urinary bladder cancer
    Florian Hitzenbichler
    Department of Internal Medicine I, Caritas St Josef Medical Center, University of Regensburg, Regensburg, Germany
    Pathobiology 81:53-9. 2014
    ..Several studies have investigated the influence of this SNP on disease risk and onset of various malignancies. The impact of Mdm2 SNP309 on bladder cancer is still to be established due to inconsistent data...
  15. doi request reprint Outcome of patients with ischemic-like cholangiopathy with secondary sclerosing cholangitis after liver transplantation
    Gabi I Kirchner
    Department of Internal Medicine I, University Hospital of Regensburg, Regensburg, Germany
    Scand J Gastroenterol 46:471-8. 2011
    ..Data on outcome of these patients after liver transplantation (LT) are sparse...