Research Topics
| Gerta RuckerSummaryAffiliation: University of Freiburg Country: Germany Publications
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Detail Information
Publications
Measuring inter-observer agreement in contour delineation of medical imaging in a dummy run using Fleiss' kappaG Rucker
Gerta Rücker, Institute of Medical Biometry and Medical Informatics, University Medical Center Freiburg, Stefan Meier Straße 26, 79104 Freiburg, Germany
Methods Inf Med 51:489-94. 2012..In medical imaging used for planning of radiation therapy, observers delineate contours of a treatment volume in a series of images of uniform slice thickness...
Are KISS data representative of German intensive care units? Statistical issuesG Rucker
Institute of Medical Biometry and Medical Informatics, Freiburg, Germany
Methods Inf Med 45:424-9. 2006....- Arcsine test for publication bias in meta-analyses with binary outcomesGerta Rucker
Institute of Medical Biometry and Medical Informatics, University Medical Centre, Freiburg, Germany
Stat Med 27:746-63. 2008..Arcsine tests have additional advantages that they can include trials with zero events in both arms and that they can be very easily performed using the existing software for regression tests... - Boosting qualifies capture-recapture methods for estimating the comprehensiveness of literature searches for systematic reviewsGerta Rucker
Institute of Medical Biometry and Medical Informatics, University Medical Center Freiburg, Stefan Meier Strasse 26, D 79104 Freiburg, Germany
J Clin Epidemiol 64:1364-72. 2011..We investigate the statistical feasibility of capture-recapture techniques with model selection for estimating the number of missing references in literature searches using two systematic reviews in gastroenterology and hematology... - Detecting and adjusting for small-study effects in meta-analysisGerta Rucker
Institute of Medical Biometry and Medical Informatics, University Medical Center, Stefan Meier Strasse 26, D 79104 Freiburg, Germany
Biom J 53:351-68. 2011.... - Summary ROC curve based on a weighted Youden index for selecting an optimal cutpoint in meta-analysis of diagnostic accuracyGerta Rucker
Institute of Medical Biometry and Medical Informatics, University Medical Center, Freiburg, Germany
Stat Med 29:3069-78. 2010..Our approach leads in a natural way to a new, model-based proposal for a summary ROC curve. It is illustrated using an example from the literature... - Why add anything to nothing? The arcsine difference as a measure of treatment effect in meta-analysis with zero cellsGerta Rucker
Institute of Medical Biometry and Medical Informatics, University Medical Centre Freiburg, Stefan Meier Strasse 26, D 79104 Freiburg, Germany
Stat Med 28:721-38. 2009..However, parameter estimation is biased if the groups are markedly unbalanced. Though, from a theoretical viewpoint, the AS is a natural choice, its practical use is likely to continue to be limited by its less direct interpretation... - Treatment-effect estimates adjusted for small-study effects via a limit meta-analysisGerta Rucker
Institute of Medical Biometry and Medical Informatics, University Medical Center, 79104 Freiburg, Germany
Biostatistics 12:122-42. 2011..These limit meta-analysis estimators were also relatively robust against heterogeneity and one of them had a relatively small coverage error... 
The relationship between quality of research and citation frequencyPentti Nieminen
Medical Informatics Group, University of Oulu, P O Box 5000, FIN 90014 Oulu, Finland
BMC Med Res Methodol 6:42. 2006..The objective of this study is to assess whether statistical reporting and statistical errors in the analysis of the primary outcome are associated with the number of citations received...- Undue reliance on I(2) in assessing heterogeneity may misleadGerta Rucker
Institute of Medical Biometry and Medical Informatics, University Medical Center Freiburg, Germany
BMC Med Res Methodol 8:79. 2008..The heterogeneity statistic I(2), interpreted as the percentage of variability due to heterogeneity between studies rather than sampling error, depends on precision, that is, the size of the studies included... - Simpson's paradox visualized: the example of the rosiglitazone meta-analysisGerta Rucker
Institute of Medical Biometry and Medical Informatics, University Medical Center Freiburg, Germany
BMC Med Res Methodol 8:34. 2008..It can also be found in meta-analysis of randomized clinical trials. However, though readers are able to recalculate examples from hypothetical as well as real data, they may have problems to easily figure where it emerges from... - Treatment of depressive disorders in primary care--protocol of a multiple treatment systematic review of randomized controlled trialsKlaus Linde
Institute of General Practice, Technische Universitat Munchen, Orleansstrasse 47, Munich, Germany
BMC Fam Pract 12:127. 2011..We aim to systematically review and compare the available evidence for the effectiveness of pharmacological, psychological, and combined treatments for patients with depressive disorders in primary care... - Deferasirox for managing iron overload in people with thalassaemiaJoerg J Meerpohl
German Cochrane Centre, Institute of Medical Biometry and Medical Informatics and Pediatric Hematology and Oncology, Center forPediatrics and Adolescent Medicine, University Medical Center Freiburg, Freiburg, Germany
Cochrane Database Syst Rev 2:CD007476. 2012..Both deferoxamine and deferiprone have been found to be efficacious. However, a systematic review of the effectiveness and safety of the new oral chelator deferasirox in people with thalassaemia is needed... - Empirical evaluation suggests Copas selection model preferable to trim-and-fill method for selection bias in meta-analysisGuido Schwarzer
Institute of Medical Biometry and Medical Informatics, University Medical Center, Freiburg, Germany
J Clin Epidemiol 63:282-8. 2010..Copas proposed a selection model to assess the sensitivity of meta-analysis conclusions to possible selection bias. An alternative proposal is the trim-and-fill method. This article reports an empirical comparison of the two methods... - Empirical evaluation showed that the Copas selection model provided a useful summary in 80% of meta-analysesJames R Carpenter
Institute of Medical Biometry and Medical Informatics, University Medical Center, Freiburg, Germany
J Clin Epidemiol 62:624-631.e4. 2009..However, this relatively complex model awaits both reliable software and an empirical evaluation. This article reports work addressing both these issues... - Reporting of eligibility criteria of randomised trials: cohort study comparing trial protocols with subsequent articlesAnette Blümle
Department of Medical Biometry and Statistics, Institute of Medical Biometry and Medical Informatics, University Medical Center Freiburg, German Cochrane Center, Berliner Allee 29, 79110 Freiburg, Germany
BMJ 342:d1828. 2011..To determine whether and how eligibility criteria of participants prespecified in protocols of randomised trials are reported in subsequent articles... - Do journals publishing in the field of urology endorse reporting guidelines? A survey of author instructionsFrank Kunath
German Cochrane Centre, Institute of Medical Biometry and Medical Informatics, University Medical Center Freiburg, Freiburg Br, Germany kunath cochrane de
Urol Int 88:54-9. 2012..The extent to which reporting guidelines are incorporated into the author instructions of journals publishing in the field of urology remained unclear... - Statistically significant papers in psychiatry were cited more often than othersPentti Nieminen
Institute of Medical Biometry and Medical Informatics, University of Freiburg, Stefan Meier Str 26, D 79115 Freiburg, Germany
J Clin Epidemiol 60:939-46. 2007..Citations by other researchers are important in the dissemination of research findings. We aimed to investigate whether preferential citation of statistically significant articles exists in the psychiatric literature... - Do urology journals enforce trial registration? A cross-sectional study of published trialsFrank Kunath
German Cochrane Centre, Institute of Medical Biometry and Medical Informatics, University Medical Centre Freiburg, Freiburg Br, Germany
BMJ Open 1:e000430. 2011..04). Conclusions The existence of a statement about trial registration in author instructions resulted in a higher proportion of registered RCTs in those journals. Journals with higher IFs were more likely to mention trial registration... - Deferasirox for managing iron overload in people with myelodysplastic syndromeJoerg J Meerpohl
German Cochrane Centre, Institute of Medical Biometry and Medical Informatics and Pediatric Hematology and Oncology, Center for Pediatrics and Adolescent Medicine, University Medical Center Freiburg, Berliner Allee 29, Freiburg, Germany, 79110
Cochrane Database Syst Rev 11:CD007461. 2010..Since the human body has no natural means of getting rid of excess iron, iron chelation therapy is usually recommended. However, whether the new oral chelator deferasirox leads to relevant benefit is unclear...