T Rosburg

Summary

Affiliation: University of Bonn
Country: Germany

Publications

  1. doi Attention effects on sensory gating--intracranial and scalp recordings
    Timm Rosburg
    Department of Epileptology, University of Bonn, Sigmund Freud Str 25, D 53105 Bonn, Germany
    Neuroimage 48:554-63. 2009
  2. ncbi Effect of ketamine on the neuromagnetic mismatch field in healthy humans
    I Kreitschmann-Andermahr
    Department of Psychiatry, Friedrich Schiller University, D 07740 Jena, Germany
    Brain Res Cogn Brain Res 12:109-16. 2001
  3. ncbi Impaired niacin sensitivity in acute first-episode but not in multi-episode schizophrenia
    S Smesny
    Department of Psychiatry, Friedrich Schiller University Jena, Philosophenweg 3, D 07743 Jena, Germany
    Prostaglandins Leukot Essent Fatty Acids 72:393-402. 2005
  4. doi Phase-locking within human mediotemporal lobe predicts memory formation
    Juergen Fell
    Department of Epileptology, University of Bonn, Bonn, Germany
    Neuroimage 43:410-9. 2008
  5. doi Reduced auditory evoked potential component N100 in schizophrenia--a critical review
    Timm Rosburg
    Department of Epileptology, University of Bonn, Bonn, Germany
    Psychiatry Res 161:259-74. 2008
  6. ncbi Habituation of auditory evoked potentials in intracranial and extracranial recordings
    Timm Rosburg
    Department of Epileptology, University of Bonn, D 53105 Bonn, Germany
    Psychophysiology 43:137-44. 2006
  7. ncbi Short-term habituation of the intracranially recorded auditory evoked potentials P50 and N100
    Timm Rosburg
    Department of Epileptology, University of Bonn, Sigmund Freud Street 25, D 53105 Bonn, Germany
    Neurosci Lett 372:245-9. 2004
  8. ncbi The influence of repetition and famousness on the intracranially recorded temporobasal N200
    Timm Rosburg
    Department of Epileptology, University of Bonn, Bonn, Germany
    Behav Neurosci 119:876-83. 2005
  9. ncbi Effects of lorazepam on the neuromagnetic mismatch negativity (MMNm) and auditory evoked field component N100m
    Timm Rosburg
    Department of Psychiatry, Friedrich Schiller University Jena, Jena, Germany
    Neuropsychopharmacology 29:1723-33. 2004
  10. ncbi [Mismatch negativity in schizophrenia research. An indicator of early processing disorders of acoustic information]
    T Rosburg
    Klinik fur Psychiatrie, Friedrich Schiller Universitat Jena, Jena, Deutschland
    Nervenarzt 75:633-41. 2004

Detail Information

Publications34

  1. doi Attention effects on sensory gating--intracranial and scalp recordings
    Timm Rosburg
    Department of Epileptology, University of Bonn, Sigmund Freud Str 25, D 53105 Bonn, Germany
    Neuroimage 48:554-63. 2009
    ..Findings indicate that N100 and P200 gating measures can potentially be affected by attention and have to be interpreted carefully when studying clinical populations...
  2. ncbi Effect of ketamine on the neuromagnetic mismatch field in healthy humans
    I Kreitschmann-Andermahr
    Department of Psychiatry, Friedrich Schiller University, D 07740 Jena, Germany
    Brain Res Cogn Brain Res 12:109-16. 2001
    ....
  3. ncbi Impaired niacin sensitivity in acute first-episode but not in multi-episode schizophrenia
    S Smesny
    Department of Psychiatry, Friedrich Schiller University Jena, Philosophenweg 3, D 07743 Jena, Germany
    Prostaglandins Leukot Essent Fatty Acids 72:393-402. 2005
    ..Longitudinal studies have to rule out possible long-term effects of neuroleptic medication...
  4. doi Phase-locking within human mediotemporal lobe predicts memory formation
    Juergen Fell
    Department of Epileptology, University of Bonn, Bonn, Germany
    Neuroimage 43:410-9. 2008
    ..Our data suggest that early mediotemporal phase adjustments constitute a relevant mechanism underlying declarative memory encoding...
  5. doi Reduced auditory evoked potential component N100 in schizophrenia--a critical review
    Timm Rosburg
    Department of Epileptology, University of Bonn, Bonn, Germany
    Psychiatry Res 161:259-74. 2008
    ..A reduced N100 amplitude is found in first degree relatives of schizophrenia patients, but the risk of developing schizophrenia is not reflected in the N100 amplitude reduction...
  6. ncbi Habituation of auditory evoked potentials in intracranial and extracranial recordings
    Timm Rosburg
    Department of Epileptology, University of Bonn, D 53105 Bonn, Germany
    Psychophysiology 43:137-44. 2006
    ..This dissociation between the intracranial and scalp recordings might be explained by a different sensitivity of the two measurements for N100 generators...
  7. ncbi Short-term habituation of the intracranially recorded auditory evoked potentials P50 and N100
    Timm Rosburg
    Department of Epileptology, University of Bonn, Sigmund Freud Street 25, D 53105 Bonn, Germany
    Neurosci Lett 372:245-9. 2004
    ..Current results indicate that the P50 suppression as investigated in sensory gating experiments seems to be completed after the 2nd stimulus...
  8. ncbi The influence of repetition and famousness on the intracranially recorded temporobasal N200
    Timm Rosburg
    Department of Epileptology, University of Bonn, Bonn, Germany
    Behav Neurosci 119:876-83. 2005
    ..They suppose that the recognition of faces becomes observable within the N200 latency range and that the increased N200 latency reflects a feature processing additional to the holistic face processing...
  9. ncbi Effects of lorazepam on the neuromagnetic mismatch negativity (MMNm) and auditory evoked field component N100m
    Timm Rosburg
    Department of Psychiatry, Friedrich Schiller University Jena, Jena, Germany
    Neuropsychopharmacology 29:1723-33. 2004
    ..MMN studies on clinical populations have to be controlled for the recording time because of the strong habituation of this component...
  10. ncbi [Mismatch negativity in schizophrenia research. An indicator of early processing disorders of acoustic information]
    T Rosburg
    Klinik fur Psychiatrie, Friedrich Schiller Universitat Jena, Jena, Deutschland
    Nervenarzt 75:633-41. 2004
    ..Clear evidence for a hemispheric lateralization of the MMN reduction in schizophrenic patients is lacking. A hypofunction of the N-methyl-D-aspartate (NMDA) receptor is discussed as a possible explanation of this deficit...
  11. pmc Hippocampal event-related potentials to tone duration deviance in a passive oddball paradigm in humans
    Timm Rosburg
    Department of Epileptology, University of Bonn, Sigmund Freud Str 25, D 53105 Bonn, Germany
    Neuroimage 37:274-81. 2007
    ..The current study provides evidence that the MMN is part of a multistage comparison process and that the rhinal cortex is part of its underlying cortical network...
  12. doi Sensory gating in epilepsy - effects of the lateralization of hippocampal sclerosis
    Timm Rosburg
    Department of Epileptology, University of Bonn, Sigmund Freud Str 25, D 53105 Bonn, Germany
    Clin Neurophysiol 119:1310-9. 2008
    ..The role of the hippocampus in sensory gating is unresolved as yet. The current study was conducted in order to examine the effects of hippocampal lesions on the function of auditory sensory gating...
  13. doi Sensory gating in intracranial recordings--the role of phase locking
    Timm Rosburg
    Department of Epileptology, University of Bonn, Bonn, Germany
    Neuroimage 44:1041-9. 2009
    ..The reduced beta band response in response to the 1st stimulus may reflect poorer memory encoding of the 1st stimulus in poor gators. This in turn might lead to increased demands to process the 2nd stimulus...
  14. ncbi Subdural recordings of the mismatch negativity (MMN) in patients with focal epilepsy
    Timm Rosburg
    Department of Epileptology, University of Bonn, Sigmund Freud Strasse 25, D 53105 Bonn, Germany
    Brain 128:819-28. 2005
    ..Current findings have, however, to be interpreted with caution owing to the placement and limited extension of the used electrode arrays...
  15. ncbi Sensory gating of auditory evoked and induced gamma band activity in intracranial recordings
    P Trautner
    Department of Epileptology, University of Bonn, Sigmund Freud Str 25, D 53115 Bonn, Germany
    Neuroimage 32:790-8. 2006
    ..Both types of gamma band activity showed a clear attenuation with stimulus repetition...
  16. ncbi Habituation of the auditory evoked field component N100m in male patients with schizophrenia
    T Rosburg
    Department of Psychiatry, University of Jena, Philosophenweg 3, D 07740, Jena, Germany
    J Psychiatr Res 34:245-54. 2000
    ..However, this difference was related to medication with clozapine. Overall, the habituation behaviour of the N100m seems to be undisturbed in schizophrenic patients...
  17. pmc Towards a functional topography of sensory gating areas: invasive P50 recording and electrical stimulation mapping in epilepsy surgery candidates
    Martin Kurthen
    Department of Epileptology, University of Bonn, Germany
    Psychiatry Res 155:121-33. 2007
    ..Results suggest that the early stage of sensory gating already involves a top-down modulation of sensory input by frontal areas...
  18. ncbi Hemispheric differences in frequency dependent dipole orientation of the human auditory evoked field component N100m
    T Rosburg
    Department of Psychiatry, Jena University, Germany
    Neurosci Lett 258:105-8. 1998
    ..The left hemispheric dipoles were orientated on average 10.8 degrees more vertically for the 5000 Hz condition. This result points to interhemispheric differences on the level of sensory processing...
  19. ncbi The dipole location shift within the auditory evoked neuromagnetic field components N100m and mismatch negativity (MMNm)
    T Rosburg
    Department of Psychiatry, Friedrich Schiller University Jena, Philosophenweg 3, D 07743 Jena, Germany
    Clin Neurophysiol 115:906-13. 2004
    ..To investigate whether within the latency range of the neuromagnetic mismatch negativity (MMNm) a similar dipole shift can be observed as found in previous studies for the auditory evoked field component N100m...
  20. ncbi Habituation of the auditory evoked field component N100m and its dependence on stimulus duration
    T Rosburg
    Department of Psychiatry, Friedrich Schiller University Jena, Philosophenweg 3, D 07740, Jena, Germany
    Clin Neurophysiol 113:421-8. 2002
    ..In the current study we investigated the habituation of the neuromagnetic auditory evoked field (AEF) component N100m and its dependence on stimulus duration...
  21. ncbi Left hemispheric dipole locations of the neuromagnetic mismatch negativity to frequency, intensity and duration deviants
    Timm Rosburg
    Department of Psychiatry, Friedrich Schiller University, Philosophenweg 3, D 07743, Jena, Germany
    Brain Res Cogn Brain Res 16:83-90. 2003
    ..This differentiation between sources emphasizes the importance of feature analysis in MMN(m) generation...
  22. ncbi Effects of tone repetition on auditory evoked neuromagnetic fields
    Timm Rosburg
    Department of Psychiatry, Friedrich Schiller University of Jena, Philosophenweg 3, D 07743 Jena, Germany
    Clin Neurophysiol 115:898-905. 2004
    ..To investigate the impact of stimulus repetition on neuromagnetic auditory evoked fields (AEF) in the context of permanently varying auditory stimulation and uniform stimulation...
  23. ncbi Left parietal lobe activation to auditory mismatch?
    Timm Rosburg
    Department of Psychiatry, Friedrich Schiller University Jena, Jena, Germany
    Hum Brain Mapp 21:44-5; discussion 46-8. 2004
    ..Statistical Parametric Mapping of LORETA Using High-Density EEG and Individual MRI: Application to Mismatch Negativities in Schizophrenia. Hum Brain Mapp 2002;17:168-178)...
  24. doi Active suppression in the mediotemporal lobe during directed forgetting
    Eva Ludowig
    Department of Epileptology, University of Bonn, Sigmund Freud Str 25, D 53105 Bonn, Germany
    Neurobiol Learn Mem 93:352-61. 2010
    ..The increased rhinal activity in response to the TBF cue might indicate an active involvement of this structure in the suppression of hippocampal memory formation...
  25. doi Intracranially recorded memory-related potentials reveal higher posterior than anterior hippocampal involvement in verbal encoding and retrieval
    Eva Ludowig
    Department of Epileptology, University of Bonn, Bonn, Germany
    J Cogn Neurosci 20:841-51. 2008
    ..Both effects were larger the further posterior an electrode was located in the hippocampus. Findings are suggestive for a predominant posterior hippocampal involvement in both verbal encoding and retrieval...
  26. doi Two P300 generators in the hippocampal formation
    Eva Ludowig
    Department of Epileptology, University of Bonn, Bonn, Germany
    Hippocampus 20:186-95. 2010
    ..Hippocampus and subiculum are essential parts of the MTL-memory system. Their function within target detection might be to maintain a template of previous stimuli for a comparison with incoming sensory stimuli...
  27. doi The effect of face inversion on intracranial and scalp recordings of event-related potentials
    Timm Rosburg
    Department of Epileptology, University of Bonn, Bonn, Germany
    Psychophysiology 47:147-57. 2010
    ..Peak latencies did not differ between the scalp VPP and intracranial N200. Findings indicate that the lateral occipital cortex but not the ventral temporal cortex contributes primarily to the FIE observed in scalp recordings...
  28. ncbi Metabolic mapping using 2D 31P-MR spectroscopy reveals frontal and thalamic metabolic abnormalities in schizophrenia
    Stefan Smesny
    Department of Psychiatry, Friedrich Schiller University Jena, Philosophenweg 3, D 07743 Jena, Germany
    Neuroimage 35:729-37. 2007
    ..Results support the notion of disturbed phospholipid turnover in schizophrenia, probably unrelated to prior pharmacological treatment, and associated with increased energy demand...
  29. ncbi Increased calcium-independent phospholipase A2 activity in first but not in multiepisode chronic schizophrenia
    Stefan Smesny
    Department of Psychiatry, Friedrich Schiller University Jena, Jena, USA
    Biol Psychiatry 57:399-405. 2005
    ..Previous studies in chronic schizophrenia were less conclusive. To explore whether iPLA2 changes are stage dependent, we investigated serum iPLA2 activity in various stages of schizophrenia...
  30. ncbi Potential use of the topical niacin skin test in early psychosis -- a combined approach using optical reflection spectroscopy and a descriptive rating scale
    Stefan Smesny
    Department of Psychiatry, University of Jena, Philosophenweg 3, D 07743, Jena, Germany
    J Psychiatr Res 37:237-47. 2003
    ..Niacin sensitivity in high risk populations and the specificity of impaired skin response are subjects of further investigation...
  31. ncbi Cannabinoids influence lipid-arachidonic acid pathways in schizophrenia
    Stefan Smesny
    Department of Psychiatry, Friedrich Schiller University Jena, Philosophenweg 3, D 07743 Jena, Germany
    Neuropsychopharmacology 32:2067-73. 2007
    ..Considering pre-existing vulnerability of lipid metabolism in schizophrenia, observed effects of cannabis use support the notion of a gene x environment interaction...
  32. ncbi The influence of age and gender on niacin skin test results - implications for the use as a biochemical marker in schizophrenia
    Stefan Smesny
    Department of Psychiatry, Friedrich Schiller University Jena, Philosophenweg 3, D 07743 Jena, Germany
    J Psychiatr Res 38:537-43. 2004
    ..Consideration of gender and age is strongly recommended for further clinical niacin studies...
  33. ncbi Endophenotype properties of niacin sensitivity as marker of impaired prostaglandin signalling in schizophrenia
    Stefan Smesny
    Department of Psychiatry, Friedrich Schiller University Jena, Philosophenweg 3, D 07743, Jena, Germany
    Prostaglandins Leukot Essent Fatty Acids 77:79-85. 2007
    ..Disruption of arachidonic acid pathways and prostaglandin signalling has been implicated in the pathophysiology of schizophrenia...
  34. ncbi Mid-latency auditory-evoked responses and sensory gating in focal epilepsy: a preliminary exploration
    Nash N Boutros
    Wayne State University School of Medicine, Department of Psychiatry and Behavioral Neurosciences, Detroit, MI 48207, USA
    J Neuropsychiatry Clin Neurosci 18:409-16. 2006
    ..Though alteration of sensory gating can be demonstrated in epileptic patients, it seems to be qualitatively different from alterations reported in association with schizophrenia...