Christian Ries

Summary

Affiliation: University of Munich
Country: Germany

Publications

  1. ncbi request reprint The Wnt signal transduction pathway in stem cells and cancer cells: influence on cellular invasion
    Peter Neth
    Department of Clinical Chemistry and Clinical Biochemistry, Ludwig Maximilians University of Munich, Munich, Germany
    Stem Cell Rev 3:18-29. 2007
  2. doi request reprint Matrix metalloproteinase-9 expression and release from skin fibroblasts interacting with keratinocytes: Upregulation in response to sulphur mustard
    Christian Ries
    Division of Clinical Chemistry and Clinical Biochemistry, Ludwig Maximilians University of Munich, Nussbaumstrasse 20, 80336 Munich, Germany
    Toxicology 263:26-31. 2009
  3. doi request reprint Cytokine functions of TIMP-1
    Christian Ries
    Institute for Cardiovascular Prevention, Ludwig Maximilians University of Munich, Pettenkoferstrasse 9b, 80336, Munich, Germany
    Cell Mol Life Sci 71:659-72. 2014
  4. ncbi request reprint MMP-2, MT1-MMP, and TIMP-2 are essential for the invasive capacity of human mesenchymal stem cells: differential regulation by inflammatory cytokines
    Christian Ries
    Division of Clinical Chemistry and Clinical Biochemistry, Surgical Department, Ludwig Maximillians University of Munich, Nussbaumstrasse 20, 80336 Munich, Germany
    Blood 109:4055-63. 2007
  5. pmc Identification of a novel 82 kDa proMMP-9 species associated with the surface of leukaemic cells: (auto-)catalytic activation and resistance to inhibition by TIMP-1
    Christian Ries
    Division of Clinical Chemistry and Clinical Biochemistry in the Surgical Department, Ludwig Maximilians University of Munich, 80336 Munich, Germany
    Biochem J 405:547-58. 2007
  6. pmc Tissue inhibitor of metalloproteinase-1 (TIMP-1) regulates mesenchymal stem cells through let-7f microRNA and Wnt/β-catenin signaling
    Virginia Egea
    Division of Clinical Chemistry and Clinical Biochemistry, Surgical Department, Ludwig Maximilians University, 80336 Munich, Germany
    Proc Natl Acad Sci U S A 109:E309-16. 2012
  7. doi request reprint Sulfur mustard induces differentiation in human primary keratinocytes: opposite roles of p38 and ERK1/2 MAPK
    Tanja Popp
    Division of Clinical Chemistry and Clinical Biochemistry, Ludwig Maximilians University of Munich, Nussbaumstrasse 20, 80336 Munich, Germany
    Toxicol Lett 204:43-51. 2011
  8. doi request reprint Wnt signalling in mouse mesenchymal stem cells: impact on proliferation, invasion and MMP expression
    Marisa Karow
    Division of Clinical Chemistry and Clinical Biochemistry, Department of Surgery, Ludwig Maximilians University of Munich, Munich, Germany
    J Cell Mol Med 13:2506-20. 2009
  9. ncbi request reprint Wnt signaling regulates the invasion capacity of human mesenchymal stem cells
    Peter Neth
    Department of Surgery, Division of Clinical Chemistry and Clinical Biochemistry, Ludwig Maximilians University, Munich, Germany
    Stem Cells 24:1892-903. 2006
  10. doi request reprint IKK-2 is required for TNF-alpha-induced invasion and proliferation of human mesenchymal stem cells
    Wolfgang Bocker
    Experimental Surgery and Regenerative Medicine, Department of Surgery, University of Munich LMU, Nussbaumstrasse 20, 80336, Munich, Germany
    J Mol Med (Berl) 86:1183-92. 2008

Collaborators

Detail Information

Publications13

  1. ncbi request reprint The Wnt signal transduction pathway in stem cells and cancer cells: influence on cellular invasion
    Peter Neth
    Department of Clinical Chemistry and Clinical Biochemistry, Ludwig Maximilians University of Munich, Munich, Germany
    Stem Cell Rev 3:18-29. 2007
    ..Finally, the consequences towards future drug-mediated therapeutical modifications of Wnt signaling in stem cells and tumor cells are highlighted...
  2. doi request reprint Matrix metalloproteinase-9 expression and release from skin fibroblasts interacting with keratinocytes: Upregulation in response to sulphur mustard
    Christian Ries
    Division of Clinical Chemistry and Clinical Biochemistry, Ludwig Maximilians University of Munich, Nussbaumstrasse 20, 80336 Munich, Germany
    Toxicology 263:26-31. 2009
    ..This provides a potential mechanism probably contributing to SM-evoked tissue injury in vivo...
  3. doi request reprint Cytokine functions of TIMP-1
    Christian Ries
    Institute for Cardiovascular Prevention, Ludwig Maximilians University of Munich, Pettenkoferstrasse 9b, 80336, Munich, Germany
    Cell Mol Life Sci 71:659-72. 2014
    ....
  4. ncbi request reprint MMP-2, MT1-MMP, and TIMP-2 are essential for the invasive capacity of human mesenchymal stem cells: differential regulation by inflammatory cytokines
    Christian Ries
    Division of Clinical Chemistry and Clinical Biochemistry, Surgical Department, Ludwig Maximillians University of Munich, Nussbaumstrasse 20, 80336 Munich, Germany
    Blood 109:4055-63. 2007
    ....
  5. pmc Identification of a novel 82 kDa proMMP-9 species associated with the surface of leukaemic cells: (auto-)catalytic activation and resistance to inhibition by TIMP-1
    Christian Ries
    Division of Clinical Chemistry and Clinical Biochemistry in the Surgical Department, Ludwig Maximilians University of Munich, 80336 Munich, Germany
    Biochem J 405:547-58. 2007
    ..Thus, the 82 kDa proMMP-9 expressed on the surface of malignant cells may escape inhibition by natural TIMP-1, thereby facilitating cellular invasion in vivo...
  6. pmc Tissue inhibitor of metalloproteinase-1 (TIMP-1) regulates mesenchymal stem cells through let-7f microRNA and Wnt/β-catenin signaling
    Virginia Egea
    Division of Clinical Chemistry and Clinical Biochemistry, Surgical Department, Ludwig Maximilians University, 80336 Munich, Germany
    Proc Natl Acad Sci U S A 109:E309-16. 2012
    ..Our results demonstrate that TIMP-1 is a direct regulator of hMSC functions and reveal a regulatory network in which let-7f modulates Wnt/β-catenin activity...
  7. doi request reprint Sulfur mustard induces differentiation in human primary keratinocytes: opposite roles of p38 and ERK1/2 MAPK
    Tanja Popp
    Division of Clinical Chemistry and Clinical Biochemistry, Ludwig Maximilians University of Munich, Nussbaumstrasse 20, 80336 Munich, Germany
    Toxicol Lett 204:43-51. 2011
    ..Thus, our findings indicate that SM triggers premature differentiation in keratinocytes via p38 activity which may contribute to impaired regeneration of SM-injured skin...
  8. doi request reprint Wnt signalling in mouse mesenchymal stem cells: impact on proliferation, invasion and MMP expression
    Marisa Karow
    Division of Clinical Chemistry and Clinical Biochemistry, Department of Surgery, Ludwig Maximilians University of Munich, Munich, Germany
    J Cell Mol Med 13:2506-20. 2009
    ..Thus, our data advice caution when mouse model systems represent the pre-clinical validation of MSC-mediated therapeutical approaches...
  9. ncbi request reprint Wnt signaling regulates the invasion capacity of human mesenchymal stem cells
    Peter Neth
    Department of Surgery, Division of Clinical Chemistry and Clinical Biochemistry, Ludwig Maximilians University, Munich, Germany
    Stem Cells 24:1892-903. 2006
    ....
  10. doi request reprint IKK-2 is required for TNF-alpha-induced invasion and proliferation of human mesenchymal stem cells
    Wolfgang Bocker
    Experimental Surgery and Regenerative Medicine, Department of Surgery, University of Munich LMU, Nussbaumstrasse 20, 80336, Munich, Germany
    J Mol Med (Berl) 86:1183-92. 2008
    ..Therefore, hMSC recruitment to sites of tissue injury may, at least in part, be regulated by the NF-kappaB signal transduction pathway...
  11. ncbi request reprint Modulation of autocrine TNF-alpha-stimulated matrix metalloproteinase 9 (MMP-9) expression by mitogen-activated protein kinases in THP-1 monocytic cells
    Michael Heidinger
    Division of Clinical Chemistry and Clinical Biochemistry, Surgical Department of the Ludwig Maximilians University, D 80336 Munich, Germany
    Biol Chem 387:69-78. 2006
    ..These findings suggest ERK1/2 rather than p38 and JNK as a reasonable target to specifically block MMP-9 expression using MAPK inhibitors in therapeutic applications...
  12. ncbi request reprint The calpastatin-derived calpain inhibitor CP1B reduces mRNA expression of matrix metalloproteinase-2 and -9 and invasion by leukemic THP-1 cells
    Oliver Popp
    Abteilung für Klinische Chemie und Klinische Biochemie, Chirurgische Klinik Innenstadt, Klinikum der LMU München, Nussbaumstr 20, D 80336 MUnchen, Germany
    Biol Chem 384:951-8. 2003
    ..This is the first report showing that the calpain/calpastatin system mediates MMP-mRNA expression of the leukemic THP-1 cells and as a consequence their invasiveness...
  13. ncbi request reprint Identification of a signal transduction pathway that regulates MMP-9 mRNA expression in glomerular injury
    Irene von Lüttichau
    Medizinische Poliklinik, Ludwig Maximilians Universitat, Munchen, Germany
    Biol Chem 383:1271-5. 2002
    ....