Research Topics
Species | Herbert RiechelmannSummaryAffiliation: University of Ulm Country: Germany Publications
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Detail Information
Publications
Trifunctional bispecific antibody-induced tumor cell lysis of squamous cell carcinomas of the upper aerodigestive tractSilke S Gronau
Department of Otorhinolaryngology Head and Neck Surgery, University of Ulm, Prittwitzstr 43, 89075 Ulm, Germany
Head Neck 27:376-82. 2005..tbAB-induced tumor cytotoxicity was assessed in an autologous human ex vivo system...
Phase I trial with the CD44v6-targeting immunoconjugate bivatuzumab mertansine in head and neck squamous cell carcinomaHerbert Riechelmann
Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital of Ulm, Frauensteige 12, 89075 Ulm, Germany
Oral Oncol 44:823-9. 2008..Binding to CD44v6 on skin keratinocytes mediated serious skin toxicity with a fatal outcome in a parallel trial, which led to the termination of the development program of bivatuzumab mertansine and the present study...- Adoptive therapy of head and neck squamous cell carcinoma with antibody coated immune cells: a pilot clinical trialHerbert Riechelmann
Department of Otorhinolaryngology, University Ulm, Ulm, Germany
Cancer Immunol Immunother 56:1397-406. 2007..Intravenous application of therapeutic antibodies may result in intravascular cytokine release... 
Differential response of Mono Mac 6, BEAS-2B, and Jurkat cells to indoor dustHerbert Riechelmann
Department of Otorhinolaryngology, University Hospital Center, Ulm, Germany
Environ Health Perspect 115:1325-32. 2007..Airway toxicity of indoor dust is not sufficiently understood...- Pharmacokinetics, immunogenicity and safety of bivatuzumab mertansine, a novel CD44v6-targeting immunoconjugate, in patients with squamous cell carcinoma of the head and neckAlexander Sauter
Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Mannheim, Germany
Int J Oncol 30:927-35. 2007..Dose individualization according to body size (weight or body surface area) was found to be appropriate and is recommended for the novel immunoconjugate... - A controlled challenge study on di(2-ethylhexyl) phthalate (DEHP) in house dust and the immune response in human nasal mucosa of allergic subjectsTom Deutschle
Department of Otorhinolaryngology, University of Ulm, Medical School, Ulm, Germany
Environ Health Perspect 116:1487-93. 2008..Few studies have yet addressed the effects of di(2-ethylhexyl) phthalate (DEHP) in house dust on human nasal mucosa... - Effect of nasal antifungal therapy on nasal cell activation markers in chronic rhinosinusitisMichael Weschta
Department of Otorhinolaryngology Head and Neck Surgery, University of Ulm, Ulm, Germany
Arch Otolaryngol Head Neck Surg 132:743-7. 2006..To examine the effect of nasal antifungal treatment on eosinophil cationic protein (ECP) and tryptase levels in samples of nasal lavage fluid from patients with chronic rhinosinusitis and nasal polyps... - Nasal fractional exhaled nitric oxide analysis with a novel hand-held deviceMichael Weschta
Department of Otorhinolaryngology and Head and Neck Surgery, University Hospital of Ulm, Germany
Rhinology 46:23-7. 2008..To assess the performance of a novel hand-held nitric oxide (NO) analyzer in the measurement of nasal fractional exhaled NO (FE(NO))... - The tumor antigens RHAMM and G250/CAIX are expressed in head and neck squamous cell carcinomas and elicit specific CD8+ T cell responsesAnita Schmitt
Department of Internal Medicine III, University of Ulm, Ulm, Germany
Int J Oncol 34:629-39. 2009..RHAMM and G250 are expressed at high frequency and high protein level in HNSCCs and are recognized by cytotoxic CD8+ effector T cells. Therefore both TAAs constitute interesting targets for T cell based immunotherapies for HNSCC... - The bacteriology of chronic rhinosinusitis with and without nasal polypsAndrea Niederfuhr
Department of Otorhinolaryngology, University Hospital of Ulm, Robert Koch Strasse 8, 89081 Ulm, Germany
Arch Otolaryngol Head Neck Surg 135:131-6. 2009..To compare the bacteriologic findings in ethmoidal biopsy specimens and nasal lavage samples from healthy control patients and from patients with chronic rhinosinusitis (CRS) with nasal polyps (CRSNP+) and without nasal polyps (CRSNP-)... - Ratio of myeloid and plasmacytoid dendritic cells and TH2 skew in CRS with nasal polypsH Kirsche
Department of Otorhinolaryngology Head and Neck Surgery, University Hospital of Ulm, Ulm, Germany
Allergy 65:24-31. 2010..The role of myeloid and plasmacytoid dendritic cells and its consequences for the T(H)2 skew in chronic rhinosinusitis (CRS) with nasal polyps (CRSNP(+)) should be detailed... - Nasal toxicity of benzalkonium chlorideHerbert Riechelmann
Department of Otorhinolaryngology, University of Ulm, Medical School Prittwitzstr 43, 89075 Ulm, Germany
Am J Rhinol 18:291-9. 2004..No BAC-related proinflammatory effects have been observed. At higher doses than normally used therapeutically, BAC caused significant nasal irritation... - Nasal cytologies--impact of sampling method, repeated sampling and interobserver variabilityTom Deutschle
Department of Otorhinolaryngology, University of Ulm, Medical School, Ulm, Germany
Rhinology 43:215-20. 2005..95-0.98). For studies that require repeated sampling, the lavage will be recommended as best suitable to obtain nasal cytologies... - Diagnostic accuracy of peak nasal inspiratory flow and rhinomanometry in functional rhinosurgeryChristian Bermüller
Department of Otorhinolaryngology Head and Neck Surgery, University Hospital of Ulm, Ulm, Germany
Laryngoscope 118:605-10. 2008..The reference standard was clinical judgment based on all clinical data available... - Short-term exposure to urban dust alters the mediator release of human nasal mucosaHerbert Riechelmann
University of Ulm, Medical School, Department of Otorhinolaryngology, Ulm, Germany
J Occup Environ Med 46:316-22. 2004..These results provide experimental support for recent epidemiological observations that short-term increase of outdoor particulate matter concentration increases the frequency of upper respiratory diseases... - Genotype and phenotype of glutathione-S-transferase in patients with head and neck carcinomaDiemut Konig-Greger
Department of Otorhinolaryngology, Institute of Clinical Chemistry, University of Ulm, Germany
Otolaryngol Head Neck Surg 130:718-25. 2004..The aim of this study was to investigate the influence of the GSTM1-null-genotype on the level of GSTM enzyme concentration and on the enzyme activity of GST in patients with head and neck cancer (HNC)... - Fungus culture and PCR in nasal lavage samples of patients with chronic rhinosinusitisDoreen Polzehl
Department of Otorhinolaryngology, University of Ulm, Prittwitzstrasse 43, 89075 Ulm, Germany
J Med Microbiol 54:31-7. 2005..This study demonstrated that PCR and conventional culture techniques could be complementary diagnostic techniques to detect fungi in nasal specimens from CRS patients... - Three-step reconstruction of complex saddle nose deformitiesHerbert Riechelmann
Department of Otorhinolaryngology, University of Ulm Medical School, Ulm, Germany
Arch Otolaryngol Head Neck Surg 130:334-8. 2004..To evaluate a reproducible surgical technique for augmentation rhinoplasty of complex saddle nose deformities, which are characterized by substantial loss of nasal structural support and result in multiple nasal abnormalities... - Comparison of conjunctival and nasal provocation test in allergic rhinitis to house dust miteHerbert Riechelmann
Department of Otorhinolaryngology, University of Ulm, Germany
Int Arch Allergy Immunol 130:51-9. 2003..Since NPTs are laborious, conjunctival provocation tests (CPTs) appear as an attractive alternative. The concordance of CPTs and NPTs with house dust mite allergen extract in sensitized and nonsensitized subjects should be evaluated... - Effects of low-toxicity particulate matter on human nasal functionHerbert Riechelmann
Department of Otorhinolaryngology, University of Ulm, Medical School, Prittwitzstr 43, Ulm 89075, Germany
J Occup Environ Med 45:54-60. 2003..03) was observed. The results indicate that acute exposure to low-toxicity particulate matter in concentrations frequently encountered in western agglomeration areas may affect nasal functions and cause nasal symptoms...