Herbert Riechelmann

Summary

Affiliation: University of Ulm
Country: Germany

Publications

  1. ncbi request reprint Trifunctional bispecific antibody-induced tumor cell lysis of squamous cell carcinomas of the upper aerodigestive tract
    Silke S Gronau
    Department of Otorhinolaryngology Head and Neck Surgery, University of Ulm, Prittwitzstr 43, 89075 Ulm, Germany
    Head Neck 27:376-82. 2005
  2. doi request reprint Phase I trial with the CD44v6-targeting immunoconjugate bivatuzumab mertansine in head and neck squamous cell carcinoma
    Herbert Riechelmann
    Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital of Ulm, Frauensteige 12, 89075 Ulm, Germany
    Oral Oncol 44:823-9. 2008
  3. ncbi request reprint Adoptive therapy of head and neck squamous cell carcinoma with antibody coated immune cells: a pilot clinical trial
    Herbert Riechelmann
    Department of Otorhinolaryngology, University Ulm, Ulm, Germany
    Cancer Immunol Immunother 56:1397-406. 2007
  4. pmc Differential response of Mono Mac 6, BEAS-2B, and Jurkat cells to indoor dust
    Herbert Riechelmann
    Department of Otorhinolaryngology, University Hospital Center, Ulm, Germany
    Environ Health Perspect 115:1325-32. 2007
  5. ncbi request reprint Pharmacokinetics, immunogenicity and safety of bivatuzumab mertansine, a novel CD44v6-targeting immunoconjugate, in patients with squamous cell carcinoma of the head and neck
    Alexander Sauter
    Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Mannheim, Germany
    Int J Oncol 30:927-35. 2007
  6. pmc A controlled challenge study on di(2-ethylhexyl) phthalate (DEHP) in house dust and the immune response in human nasal mucosa of allergic subjects
    Tom Deutschle
    Department of Otorhinolaryngology, University of Ulm, Medical School, Ulm, Germany
    Environ Health Perspect 116:1487-93. 2008
  7. ncbi request reprint Effect of nasal antifungal therapy on nasal cell activation markers in chronic rhinosinusitis
    Michael Weschta
    Department of Otorhinolaryngology Head and Neck Surgery, University of Ulm, Ulm, Germany
    Arch Otolaryngol Head Neck Surg 132:743-7. 2006
  8. ncbi request reprint Nasal fractional exhaled nitric oxide analysis with a novel hand-held device
    Michael Weschta
    Department of Otorhinolaryngology and Head and Neck Surgery, University Hospital of Ulm, Germany
    Rhinology 46:23-7. 2008
  9. ncbi request reprint The tumor antigens RHAMM and G250/CAIX are expressed in head and neck squamous cell carcinomas and elicit specific CD8+ T cell responses
    Anita Schmitt
    Department of Internal Medicine III, University of Ulm, Ulm, Germany
    Int J Oncol 34:629-39. 2009
  10. doi request reprint The bacteriology of chronic rhinosinusitis with and without nasal polyps
    Andrea Niederfuhr
    Department of Otorhinolaryngology, University Hospital of Ulm, Robert Koch Strasse 8, 89081 Ulm, Germany
    Arch Otolaryngol Head Neck Surg 135:131-6. 2009

Collaborators

Detail Information

Publications20

  1. ncbi request reprint Trifunctional bispecific antibody-induced tumor cell lysis of squamous cell carcinomas of the upper aerodigestive tract
    Silke S Gronau
    Department of Otorhinolaryngology Head and Neck Surgery, University of Ulm, Prittwitzstr 43, 89075 Ulm, Germany
    Head Neck 27:376-82. 2005
    ..tbAB-induced tumor cytotoxicity was assessed in an autologous human ex vivo system...
  2. doi request reprint Phase I trial with the CD44v6-targeting immunoconjugate bivatuzumab mertansine in head and neck squamous cell carcinoma
    Herbert Riechelmann
    Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital of Ulm, Frauensteige 12, 89075 Ulm, Germany
    Oral Oncol 44:823-9. 2008
    ..Binding to CD44v6 on skin keratinocytes mediated serious skin toxicity with a fatal outcome in a parallel trial, which led to the termination of the development program of bivatuzumab mertansine and the present study...
  3. ncbi request reprint Adoptive therapy of head and neck squamous cell carcinoma with antibody coated immune cells: a pilot clinical trial
    Herbert Riechelmann
    Department of Otorhinolaryngology, University Ulm, Ulm, Germany
    Cancer Immunol Immunother 56:1397-406. 2007
    ..Intravenous application of therapeutic antibodies may result in intravascular cytokine release...
  4. pmc Differential response of Mono Mac 6, BEAS-2B, and Jurkat cells to indoor dust
    Herbert Riechelmann
    Department of Otorhinolaryngology, University Hospital Center, Ulm, Germany
    Environ Health Perspect 115:1325-32. 2007
    ..Airway toxicity of indoor dust is not sufficiently understood...
  5. ncbi request reprint Pharmacokinetics, immunogenicity and safety of bivatuzumab mertansine, a novel CD44v6-targeting immunoconjugate, in patients with squamous cell carcinoma of the head and neck
    Alexander Sauter
    Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Mannheim, Germany
    Int J Oncol 30:927-35. 2007
    ..Dose individualization according to body size (weight or body surface area) was found to be appropriate and is recommended for the novel immunoconjugate...
  6. pmc A controlled challenge study on di(2-ethylhexyl) phthalate (DEHP) in house dust and the immune response in human nasal mucosa of allergic subjects
    Tom Deutschle
    Department of Otorhinolaryngology, University of Ulm, Medical School, Ulm, Germany
    Environ Health Perspect 116:1487-93. 2008
    ..Few studies have yet addressed the effects of di(2-ethylhexyl) phthalate (DEHP) in house dust on human nasal mucosa...
  7. ncbi request reprint Effect of nasal antifungal therapy on nasal cell activation markers in chronic rhinosinusitis
    Michael Weschta
    Department of Otorhinolaryngology Head and Neck Surgery, University of Ulm, Ulm, Germany
    Arch Otolaryngol Head Neck Surg 132:743-7. 2006
    ..To examine the effect of nasal antifungal treatment on eosinophil cationic protein (ECP) and tryptase levels in samples of nasal lavage fluid from patients with chronic rhinosinusitis and nasal polyps...
  8. ncbi request reprint Nasal fractional exhaled nitric oxide analysis with a novel hand-held device
    Michael Weschta
    Department of Otorhinolaryngology and Head and Neck Surgery, University Hospital of Ulm, Germany
    Rhinology 46:23-7. 2008
    ..To assess the performance of a novel hand-held nitric oxide (NO) analyzer in the measurement of nasal fractional exhaled NO (FE(NO))...
  9. ncbi request reprint The tumor antigens RHAMM and G250/CAIX are expressed in head and neck squamous cell carcinomas and elicit specific CD8+ T cell responses
    Anita Schmitt
    Department of Internal Medicine III, University of Ulm, Ulm, Germany
    Int J Oncol 34:629-39. 2009
    ..RHAMM and G250 are expressed at high frequency and high protein level in HNSCCs and are recognized by cytotoxic CD8+ effector T cells. Therefore both TAAs constitute interesting targets for T cell based immunotherapies for HNSCC...
  10. doi request reprint The bacteriology of chronic rhinosinusitis with and without nasal polyps
    Andrea Niederfuhr
    Department of Otorhinolaryngology, University Hospital of Ulm, Robert Koch Strasse 8, 89081 Ulm, Germany
    Arch Otolaryngol Head Neck Surg 135:131-6. 2009
    ..To compare the bacteriologic findings in ethmoidal biopsy specimens and nasal lavage samples from healthy control patients and from patients with chronic rhinosinusitis (CRS) with nasal polyps (CRSNP+) and without nasal polyps (CRSNP-)...
  11. doi request reprint Ratio of myeloid and plasmacytoid dendritic cells and TH2 skew in CRS with nasal polyps
    H Kirsche
    Department of Otorhinolaryngology Head and Neck Surgery, University Hospital of Ulm, Ulm, Germany
    Allergy 65:24-31. 2010
    ..The role of myeloid and plasmacytoid dendritic cells and its consequences for the T(H)2 skew in chronic rhinosinusitis (CRS) with nasal polyps (CRSNP(+)) should be detailed...
  12. ncbi request reprint Nasal toxicity of benzalkonium chloride
    Herbert Riechelmann
    Department of Otorhinolaryngology, University of Ulm, Medical School Prittwitzstr 43, 89075 Ulm, Germany
    Am J Rhinol 18:291-9. 2004
    ..Benzalkonium chloride (BAC) is added to nasal preparations to prevent microbial contamination. Adverse effects of BAC on human nasal mucosa should be evaluated...
  13. ncbi request reprint Nasal cytologies--impact of sampling method, repeated sampling and interobserver variability
    Tom Deutschle
    Department of Otorhinolaryngology, University of Ulm, Medical School, Ulm, Germany
    Rhinology 43:215-20. 2005
    ..95-0.98). For studies that require repeated sampling, the lavage will be recommended as best suitable to obtain nasal cytologies...
  14. doi request reprint Diagnostic accuracy of peak nasal inspiratory flow and rhinomanometry in functional rhinosurgery
    Christian Bermüller
    Department of Otorhinolaryngology Head and Neck Surgery, University Hospital of Ulm, Ulm, Germany
    Laryngoscope 118:605-10. 2008
    ..The reference standard was clinical judgment based on all clinical data available...
  15. ncbi request reprint Short-term exposure to urban dust alters the mediator release of human nasal mucosa
    Herbert Riechelmann
    University of Ulm, Medical School, Department of Otorhinolaryngology, Ulm, Germany
    J Occup Environ Med 46:316-22. 2004
    ..Report the investigators' conclusions as to whether exposure to urban dust is a cause of persistent inflammation and chronic airway disease...
  16. ncbi request reprint Genotype and phenotype of glutathione-S-transferase in patients with head and neck carcinoma
    Diemut Konig-Greger
    Department of Otorhinolaryngology, Institute of Clinical Chemistry, University of Ulm, Germany
    Otolaryngol Head Neck Surg 130:718-25. 2004
    ..The aim of this study was to investigate the influence of the GSTM1-null-genotype on the level of GSTM enzyme concentration and on the enzyme activity of GST in patients with head and neck cancer (HNC)...
  17. ncbi request reprint Fungus culture and PCR in nasal lavage samples of patients with chronic rhinosinusitis
    Doreen Polzehl
    Department of Otorhinolaryngology, University of Ulm, Prittwitzstrasse 43, 89075 Ulm, Germany
    J Med Microbiol 54:31-7. 2005
    ..This study demonstrated that PCR and conventional culture techniques could be complementary diagnostic techniques to detect fungi in nasal specimens from CRS patients...
  18. ncbi request reprint Three-step reconstruction of complex saddle nose deformities
    Herbert Riechelmann
    Department of Otorhinolaryngology, University of Ulm Medical School, Ulm, Germany
    Arch Otolaryngol Head Neck Surg 130:334-8. 2004
    ..To evaluate a reproducible surgical technique for augmentation rhinoplasty of complex saddle nose deformities, which are characterized by substantial loss of nasal structural support and result in multiple nasal abnormalities...
  19. ncbi request reprint Comparison of conjunctival and nasal provocation test in allergic rhinitis to house dust mite
    Herbert Riechelmann
    Department of Otorhinolaryngology, University of Ulm, Germany
    Int Arch Allergy Immunol 130:51-9. 2003
    ..Since NPTs are laborious, conjunctival provocation tests (CPTs) appear as an attractive alternative. The concordance of CPTs and NPTs with house dust mite allergen extract in sensitized and nonsensitized subjects should be evaluated...
  20. ncbi request reprint Effects of low-toxicity particulate matter on human nasal function
    Herbert Riechelmann
    Department of Otorhinolaryngology, University of Ulm, Medical School, Prittwitzstr 43, Ulm 89075, Germany
    J Occup Environ Med 45:54-60. 2003
    ..03) was observed. The results indicate that acute exposure to low-toxicity particulate matter in concentrations frequently encountered in western agglomeration areas may affect nasal functions and cause nasal symptoms...