E Raskopf

Summary

Affiliation: University of Bonn
Country: Germany

Publications

  1. doi siRNA targeting VEGF inhibits hepatocellular carcinoma growth and tumor angiogenesis in vivo
    Esther Raskopf
    Department of Internal Medicine I, University of Bonn, Sigmund Freud Str 25, 53105 Bonn, Germany
    J Hepatol 49:977-84. 2008
  2. pmc Toxic damage increases angiogenesis and metastasis in fibrotic livers via PECAM-1
    Esther Raskopf
    Department of Inner Medicine, University Hospital Bonn, Sigmund Freud Strase 25, 53107 Bonn, Germany
    Biomed Res Int 2014:712893. 2014
  3. ncbi Apoptotic potency of angiostatic compounds in the treatment of cancer
    Esther Raskopf
    Department of Inner Medicine I, University Hospital Bonn, Sigmund Freud Strasse 25, Bonn, Germany
    Curr Pharm Biotechnol 13:2283-9. 2012
  4. ncbi Combination of hypoxia and RNA-interference targeting VEGF induces apoptosis in hepatoma cells via autocrine mechanisms
    Esther Raskopf
    Department of Internal Medicine I, University of Bonn, Sigmund Freud Strasse 25, Bonn Germany
    Curr Pharm Biotechnol 13:2290-8. 2012
  5. doi Plasminogen fragment K1-3 inhibits expression of adhesion molecules and experimental HCC recurrence in the liver
    Esther Raskopf
    Department of Internal Medicine I, University of Bonn, Bonn, Germany
    Int J Colorectal Dis 24:837-44. 2009
  6. doi Inhibition of neuropilin-1 by RNA-interference and its angiostatic potential in the treatment of hepatocellular carcinoma
    E Raskopf
    Department of Inner Medicine I, University of Bonn, Medical School, Bonn Germany
    Z Gastroenterol 48:21-7. 2010
  7. ncbi Increased VEGF levels induced by anti-VEGF treatment are independent of tumor burden in colorectal carcinomas in mice
    V Schmitz
    Department of Internal Medicine I, University Hospital, Bonn, Germany
    Gene Ther 13:1198-205. 2006

Detail Information

Publications7

  1. doi siRNA targeting VEGF inhibits hepatocellular carcinoma growth and tumor angiogenesis in vivo
    Esther Raskopf
    Department of Internal Medicine I, University of Bonn, Sigmund Freud Str 25, 53105 Bonn, Germany
    J Hepatol 49:977-84. 2008
    ..We have investigated whether siRNA targeted against VEGF inhibits functional properties of endothelial cells in vitro and HCC tumor growth and blood vessel formation in vivo...
  2. pmc Toxic damage increases angiogenesis and metastasis in fibrotic livers via PECAM-1
    Esther Raskopf
    Department of Inner Medicine, University Hospital Bonn, Sigmund Freud Strase 25, 53107 Bonn, Germany
    Biomed Res Int 2014:712893. 2014
    ..Blockade of increased PECAM-1 expression could be a promising tool to inhibit fibrogenesis and metastasis in the liver...
  3. ncbi Apoptotic potency of angiostatic compounds in the treatment of cancer
    Esther Raskopf
    Department of Inner Medicine I, University Hospital Bonn, Sigmund Freud Strasse 25, Bonn, Germany
    Curr Pharm Biotechnol 13:2283-9. 2012
    ....
  4. ncbi Combination of hypoxia and RNA-interference targeting VEGF induces apoptosis in hepatoma cells via autocrine mechanisms
    Esther Raskopf
    Department of Internal Medicine I, University of Bonn, Sigmund Freud Strasse 25, Bonn Germany
    Curr Pharm Biotechnol 13:2290-8. 2012
    ..The direct impact on tumor cells further underscores the attractiveness of an anti-VEGF based siRNA treatment...
  5. doi Plasminogen fragment K1-3 inhibits expression of adhesion molecules and experimental HCC recurrence in the liver
    Esther Raskopf
    Department of Internal Medicine I, University of Bonn, Bonn, Germany
    Int J Colorectal Dis 24:837-44. 2009
    ..We tested a potential preventive, pre-operative strategy using plasminogen kringles 1-3 (K1-3) to overcome this hurdle...
  6. doi Inhibition of neuropilin-1 by RNA-interference and its angiostatic potential in the treatment of hepatocellular carcinoma
    E Raskopf
    Department of Inner Medicine I, University of Bonn, Medical School, Bonn Germany
    Z Gastroenterol 48:21-7. 2010
    ..In conclusion, inhibition of Nrp1 expression led to strong anti-endothelial effects, whereas tumor cells and tumor growth were not affected...
  7. ncbi Increased VEGF levels induced by anti-VEGF treatment are independent of tumor burden in colorectal carcinomas in mice
    V Schmitz
    Department of Internal Medicine I, University Hospital, Bonn, Germany
    Gene Ther 13:1198-205. 2006
    ....