Affiliation: University of Freiburg
Rampelt H, Wollweber F, Gerke C, de Boer R, van der Klei I, Bohnert M, et al
. Assembly of the Mitochondrial Cristae Organizer Mic10 Is Regulated by Mic26-Mic27 Antagonism and Cardiolipin. J Mol Biol. 2018;430:1883-1890 pubmed publisher
..Our findings indicate that the Mic10 core machinery of MICOS is regulated by several mechanisms, including interaction with cardiolipin and antagonistic actions of Mic26 and Mic27. ..
Rampelt H, Zerbes R, van der Laan M, Pfanner N. Role of the mitochondrial contact site and cristae organizing system in membrane architecture and dynamics. Biochim Biophys Acta Mol Cell Res. 2017;1864:737-746 pubmed publisher
..The functions of MICOS in mitochondrial membrane architecture and biogenesis are influenced by numerous interaction partners and the phospholipid environment. ..
Rampelt H, Pfanner N. Coordination of Two Genomes by Mitochondrial Translational Plasticity. Cell. 2016;167:308-310 pubmed publisher
..Now, Richter-Dennerlein et al. report that membrane-integrated assembly factors associate with ribosome nascent chain complexes in human mitochondria to coordinate translational plasticity with the import of subunits from the cytosol. ..
Rampelt H, Bohnert M, Zerbes R, Horvath S, Warscheid B, Pfanner N, et al
. Mic10, a Core Subunit of the Mitochondrial Contact Site and Cristae Organizing System, Interacts with the Dimeric F1Fo-ATP Synthase. J Mol Biol. 2017;429:1162-1170 pubmed publisher
..In addition to its central function in sculpting crista junctions, a fraction of Mic10 molecules interact with the cristae rim-forming F1Fo-ATP synthase. ..