Research Topics
| T J RaedlerSummaryAffiliation: University of Hamburg Country: Germany Publications
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Detail Information
Publications
Gender-specific effects in the treatment of acute schizophrenia with risperidoneT J Raedler
Department of Psychiatry, University Hospital Hamburg Eppendorf, Martinistr 52, 20246 Hamburg, Germany
Pharmacopsychiatry 39:171-4. 2006..We have now reanalysed the clinical data to assess the effects of gender on treatment and outcome...
Comparison of the in-vivo muscarinic cholinergic receptor availability in patients treated with clozapine and olanzapineThomas J Raedler
University Hospital Hamburg Eppendorf, Department of Psychiatry, Hamburg, Germany
Int J Neuropsychopharmacol 10:275-80. 2007..These results are compatible with the higher rates of anticholinergic side-effects seen with clozapine in clinical practice...
Early onset of treatment effects with oral risperidoneThomas J Raedler
Department of Psychiatry, University Medical Center Hamburg Eppendorf, Martinistr, 52, 20246 Hamburg, Germany
BMC Psychiatry 7:4. 2007..However, recent studies have challenged this concept. We therefore performed an analysis of the onset of antipsychotic treatment effects in a sample of acutely decompensated patients with schizophrenia...
CSF-studies in neuropsychiatric disordersThomas J Raedler
University Hospital Hamburg Eppendorf, Department of Psychiatry, Martinistr 52, 20246 Hamburg, Germany
Neuro Endocrinol Lett 27:297-305. 2006..We will also assess new technological advances that have made it possible to study large numbers of proteins in CSF and how these advances may change CSF-analysis in the years to come...
Megestrol attenuates the hormonal response to CCK-4-induced panic attacksThomas J Raedler
Department of Psychiatry and Psychotherapy, University Hospital Hamburg Eppendorf, Hamburg, Germany
Depress Anxiety 23:139-44. 2006..Further studies in a larger sample of subjects, including both females and patients suffering from panic disorder, seem warranted...
Adjunctive use of reboxetine in schizophreniaThomas J Raedler
University Hospital Hamburg Eppendorf, Department of Psychiatry and Psychotherapy, Martini str 52, 20246 Hamburg, Germany
Eur Psychiatry 19:366-9. 2004..We sought to study the efficacy and tolerability of the adjunctive use of reboxetine in a cohort of schizophrenic patients with prominent depressive or negative symptoms...
Risperidone in the treatment of acute schizophreniaThomas J Raedler
Department of Psychiatry, University Hospital Hamburg Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany
J Clin Psychopharmacol 24:335-8. 2004..To evaluate the efficacy of the atypical antipsychotic risperidone, we conducted an open-label observational study among admissions to a secure unit...
Lithium-induced nephropathiesThomas J Raedler
Department of Psychiatry, University Medical Center Hamburg Eppendorf, Martinistr 52, 20246 Hamburg, Germany
Psychopharmacol Bull 40:134-49. 2007..So far, no tests exist to identify subjects at risk of lithium-induced nephropathy at an early stage. Therefore, regular monitoring of creatinine and creatinine clearance are recommended in all subjects taking lithium...
Acute effects of megestrol on the hypothalamic-pituitary-adrenal axisThomas J Raedler
Department of Psychiatry and Psychotherapy, University of Hamburg Medical Center, Martinistr 52, 20246, Hamburg, Germany
Cancer Chemother Pharmacol 52:482-6. 2003..As part of an endocrine study, we evaluated the acute effects of megestrol, hydrocortisone and placebo on morning cortisol and ACTH levels...
Dose-dependent constipation with higher doses of quetiapine: a case seriesThomas J Raedler
Department of Psychiatry, University Medical Center Hamburg Eppendorf, Hamburg, Germany
Int Clin Psychopharmacol 22:244-6. 2007..We present five patients, in whom treatment with higher doses of quetiapine was associated with constipation. Our observations raise the question of dose-dependent constipation under treatment with quetiapine...
[Sex-specific differences in schizophrenia]T J Rädler
Universitatsklinikum Hamburg Eppendorf, Klinik und Poliklinik fur Psychiatrie und Psychotherapie
MMW Fortschr Med 149:32-4. 2007..Women who undergo pharmacological therapy of schizophrenia have a higher drug serum level at the same dose and a higher risk of developing certain side effects, such as hyperprolactinaemia...
Towards a muscarinic hypothesis of schizophreniaT J Raedler
Department of Psychiatry, University Medical Center Hamburg Eppendorf, Hamburg, Germany
Mol Psychiatry 12:232-46. 2007....
Involvement of plasma atrial natriuretic peptide in protracted alcohol withdrawalF Kiefer
Department of Psychiatry, University Hospital Hamburg-Eppendorf, Hamburg, Germany
Acta Psychiatr Scand 105:65-70. 2002..CONCLUSION: We suggest that a dysregulation of ANP plasma levels during alcohol withdrawal may contribute to symptoms of protracted withdrawal such as craving and anxiety...
Variability of the in vivo metabolism of clozapineThomas J Raedler
Department of Psychiatry, University Medical Center Hamburg Eppendorf, Hamburg, Germany
Clin Neuropharmacol 31:347-52. 2008..Because little is known about the rate of metabolic conversion of clozapine in vivo, we assessed the association between clozapine dose and plasma levels for clozapine and NDMC...
Muscarinic receptors in schizophrenia: is there a role for synaptic plasticity?Thomas J Raedler
Department of Psychiatry, University Hospital Hamburg Eppendorf, 20246 Hamburg, Germany
Int Rev Neurobiol 59:93-109. 2004
Capillary electrophoresis mass spectrometry as a potential tool to detect lithium-induced nephropathy: Preliminary resultsThomas J Raedler
University Medical Center Hamburg Eppendorf, Dept of Psychiatry, Martinistr 52, 20246 Hamburg, Germany
Prog Neuropsychopharmacol Biol Psychiatry 32:673-8. 2008..However, a specific screen for lithium-induced nephropathies still needs to be developed...
Central muscarinic acetylcholine receptor availability in patients treated with clozapineThomas J Raedler
Intramural Research Program, Clinical Brain Disorders Branch, National Institute of Mental Health, 10 Center Drive, Bethesda, MD 20892, USA
Neuropsychopharmacology 28:1531-7. 2003..These results may explain, at least in part, the lack of extrapyramidal side effects as well as some side effects seen with clozapine...
In vivo determination of muscarinic acetylcholine receptor availability in schizophreniaThomas J Raedler
Clinical Brain Disorders Branch, NIMH, National Institutes of Health, 10 Center Dr, 4S 235, MSC 1379, Bethesda, MD 20892 1379, USA
Am J Psychiatry 160:118-27. 2003....
