Jurgen Radons

Summary

Affiliation: University of Regensburg
Country: Germany

Publications

  1. ncbi request reprint Identification of essential regions in the cytoplasmic tail of interleukin-1 receptor accessory protein critical for interleukin-1 signaling
    Jurgen Radons
    Klinik und Poliklinik für Innere Medizin I, Universitat Regensburg, D 93042 Regensburg, Germany
    J Biol Chem 277:16456-63. 2002
  2. ncbi request reprint The interleukin 1 (IL-1) receptor accessory protein Toll/IL-1 receptor domain: analysis of putative interaction sites in vitro mutagenesis and molecular modeling
    Jurgen Radons
    Klinik und Poliklinik für Innere Medizin I, Universitat Regensburg, D 93042 Regensburg, Germany
    J Biol Chem 278:49145-53. 2003
  3. ncbi request reprint Interleukin-10 does not affect IL-1-induced interleukin-6 and metalloproteinase production in human chondrosarcoma cells, SW1353
    Jurgen Radons
    Abteilung Hämatologie und internistische Onkologie, Universitat Regensburg, D 93053 Regensburg, Germany
    Int J Mol Med 17:377-83. 2006
  4. ncbi request reprint p38MAPK mediates IL-1-induced down-regulation of aggrecan gene expression in human chondrocytes
    Jurgen Radons
    Abteilung Hämatologie und internistische Onkologie, Universitatsklinikum Regensburg, D 93053 Regensburg, Germany
    Int J Mol Med 17:661-8. 2006
  5. ncbi request reprint Immunostimulatory functions of membrane-bound and exported heat shock protein 70
    Jurgen Radons
    Abteilung Hämatologie und internistische Onkologie, Universitat Regensburg, Germany
    Exerc Immunol Rev 11:17-33. 2005
  6. ncbi request reprint Nucleofection of non-B cells with mini-Epstein-Barr virus DNA
    Jurgen Radons
    Abteilung Hämatologie und internistische Onkologie, Universitat Regensburg, Franz Josef Strauss Allee 11, D 93053 Regensburg, Germany
    J Immunol Methods 303:135-41. 2005

Detail Information

Publications6

  1. ncbi request reprint Identification of essential regions in the cytoplasmic tail of interleukin-1 receptor accessory protein critical for interleukin-1 signaling
    Jurgen Radons
    Klinik und Poliklinik für Innere Medizin I, Universitat Regensburg, D 93042 Regensburg, Germany
    J Biol Chem 277:16456-63. 2002
    ..Taken together, our data indicate that box 3 of IL-1RAcP is critical for IL-1-dependent NF-kappaB activation and stabilization of IL-2 mRNA via JNK, whereas aa 527-534 largely contribute to IL-2 promoter activation...
  2. ncbi request reprint The interleukin 1 (IL-1) receptor accessory protein Toll/IL-1 receptor domain: analysis of putative interaction sites in vitro mutagenesis and molecular modeling
    Jurgen Radons
    Klinik und Poliklinik für Innere Medizin I, Universitat Regensburg, D 93042 Regensburg, Germany
    J Biol Chem 278:49145-53. 2003
    ....
  3. ncbi request reprint Interleukin-10 does not affect IL-1-induced interleukin-6 and metalloproteinase production in human chondrosarcoma cells, SW1353
    Jurgen Radons
    Abteilung Hämatologie und internistische Onkologie, Universitat Regensburg, D 93053 Regensburg, Germany
    Int J Mol Med 17:377-83. 2006
    ..Furthermore, the unresponsiveness of chondrocytes towards IL-10 might explain the vulnerability of joint cartilage to inflammation...
  4. ncbi request reprint p38MAPK mediates IL-1-induced down-regulation of aggrecan gene expression in human chondrocytes
    Jurgen Radons
    Abteilung Hämatologie und internistische Onkologie, Universitatsklinikum Regensburg, D 93053 Regensburg, Germany
    Int J Mol Med 17:661-8. 2006
    ..The identification and characterization of these signaling pathways will enable us to develop new modulation strategies for therapeutic use in inflammatory joint diseases...
  5. ncbi request reprint Immunostimulatory functions of membrane-bound and exported heat shock protein 70
    Jurgen Radons
    Abteilung Hämatologie und internistische Onkologie, Universitat Regensburg, Germany
    Exerc Immunol Rev 11:17-33. 2005
    ....
  6. ncbi request reprint Nucleofection of non-B cells with mini-Epstein-Barr virus DNA
    Jurgen Radons
    Abteilung Hämatologie und internistische Onkologie, Universitat Regensburg, Franz Josef Strauss Allee 11, D 93053 Regensburg, Germany
    J Immunol Methods 303:135-41. 2005
    ..In summary, our results might provide the basis for the generation of non-B effector cell lines including NK cells with conserved Hsp70-reactivity...