P W Radke

Summary

Affiliation: University Hospital
Country: Germany

Publications

  1. ncbi request reprint Dexamethasone and restenosis after coronary stent implantation: new indication for an old drug?
    Peter W Radke
    Medical Clinic I and Department of Molecular Cardiovascular Research, RWTH University Hospital, Aachen, Germany
    Curr Pharm Des 10:349-55. 2004
  2. ncbi request reprint Relation of fasting insulin plasma levels to restenosis after elective coronary stent implantation in patients without diabetes mellitus
    Peter W Radke
    Medical Clinic I, RWTH University Hospital, Aachen, Germany
    Am J Cardiol 93:639-41. 2004
  3. ncbi request reprint Outcome after treatment of coronary in-stent restenosis; results from a systematic review using meta-analysis techniques
    P W Radke
    Royal Brompton and Harefield NHS Trust, London, UK
    Eur Heart J 24:266-73. 2003
  4. ncbi request reprint Treatment of in-stent restenosis using a paclitaxel-eluting stent: acute results and long-term follow-up of a matched-pair comparison with intracoronary beta-radiation therapy
    Peter W Radke
    Medical Clinic I, RWTH University Hospital, Pauwelsstrasse 30, 52057 Aachen, Germany
    Eur Heart J 25:920-5. 2004
  5. ncbi request reprint Clinical and angiographic predictors of recurrent restenosis after percutaneous transluminal rotational atherectomy for treatment of diffuse in-stent restenosis
    J vom Dahl
    Department of Cardiology, University Hospital, University of Technology, Aachen, Germany
    Am J Cardiol 83:862-7. 1999
  6. ncbi request reprint Mechanisms of acute lumen gain and recurrent restenosis after rotational atherectomy of diffuse in-stent restenosis: a quantitative angiographic and intravascular ultrasound study
    P W Radke
    Medical Clinic I, RWTH University Hospital, Aachen, Germany
    J Am Coll Cardiol 34:33-9. 1999
  7. ncbi request reprint Three-year follow-up after rotational atherectomy for the treatment of diffuse in-stent restenosis: predictors of major adverse cardiac events
    P W Radke
    Medical Clinic I, University Hospital Aachen, Aachen, Germany
    Catheter Cardiovasc Interv 53:334-40. 2001
  8. ncbi request reprint Therapeutic dissolution of an intracoronary thrombus by prolonged intravenous platelet glycoprotein IIb/IIIa antagonism
    P W Radke
    Medical Clinic I, RWTH University Hospital, Pauwelsstrasse 30, D 52057 Aachen, Germany
    J Invasive Cardiol 11:679-81. 1999
  9. ncbi request reprint Infectious agents in coronary lesions obtained by endatherectomy: pattern of distribution, coinfection, and clinical findings
    P W Radke
    Medical Clinic I, RWTH University Hospital, Aachen, Germany
    Coron Artery Dis 12:1-6. 2001
  10. ncbi request reprint Evaluation of the SOFA score: a single-center experience of a medical intensive care unit in 303 consecutive patients with predominantly cardiovascular disorders. Sequential Organ Failure Assessment
    U Janssens
    Medical Clinic I, University Hospital of Aachen, Germany
    Intensive Care Med 26:1037-45. 2000

Collaborators

Detail Information

Publications32

  1. ncbi request reprint Dexamethasone and restenosis after coronary stent implantation: new indication for an old drug?
    Peter W Radke
    Medical Clinic I and Department of Molecular Cardiovascular Research, RWTH University Hospital, Aachen, Germany
    Curr Pharm Des 10:349-55. 2004
    ....
  2. ncbi request reprint Relation of fasting insulin plasma levels to restenosis after elective coronary stent implantation in patients without diabetes mellitus
    Peter W Radke
    Medical Clinic I, RWTH University Hospital, Aachen, Germany
    Am J Cardiol 93:639-41. 2004
    ..49, p <0.0001). Furthermore, the waist-to-hip ratio and C-peptide and hemoglobin A1c serum levels were associated with the occurrence of binary angiographic restenosis...
  3. ncbi request reprint Outcome after treatment of coronary in-stent restenosis; results from a systematic review using meta-analysis techniques
    P W Radke
    Royal Brompton and Harefield NHS Trust, London, UK
    Eur Heart J 24:266-73. 2003
    ..To evaluate the clinical outcome after treatment of coronary in-stent restenosis...
  4. ncbi request reprint Treatment of in-stent restenosis using a paclitaxel-eluting stent: acute results and long-term follow-up of a matched-pair comparison with intracoronary beta-radiation therapy
    Peter W Radke
    Medical Clinic I, RWTH University Hospital, Pauwelsstrasse 30, 52057 Aachen, Germany
    Eur Heart J 25:920-5. 2004
    ..This matched-pair analysis compared the procedural and long-term clinical and angiographic outcome after treatment of diffuse ISR using a paclitaxel-eluting stent (PES) with intracoronary beta-radiation therapy...
  5. ncbi request reprint Clinical and angiographic predictors of recurrent restenosis after percutaneous transluminal rotational atherectomy for treatment of diffuse in-stent restenosis
    J vom Dahl
    Department of Cardiology, University Hospital, University of Technology, Aachen, Germany
    Am J Cardiol 83:862-7. 1999
    ..PTRA resulted in an acceptable recurrent restenosis rate in short and modestly diffuse lesion, whereas the restenosis rate in very long lesions remains high despite debulking...
  6. ncbi request reprint Mechanisms of acute lumen gain and recurrent restenosis after rotational atherectomy of diffuse in-stent restenosis: a quantitative angiographic and intravascular ultrasound study
    P W Radke
    Medical Clinic I, RWTH University Hospital, Aachen, Germany
    J Am Coll Cardiol 34:33-9. 1999
    ....
  7. ncbi request reprint Three-year follow-up after rotational atherectomy for the treatment of diffuse in-stent restenosis: predictors of major adverse cardiac events
    P W Radke
    Medical Clinic I, University Hospital Aachen, Aachen, Germany
    Catheter Cardiovasc Interv 53:334-40. 2001
    ..Three years after rotablation of in-stent restenosis, 43% of patients had experienced at least one major adverse cardiac event. Cathet Cardiovasc Intervent 2001;53:334-340...
  8. ncbi request reprint Therapeutic dissolution of an intracoronary thrombus by prolonged intravenous platelet glycoprotein IIb/IIIa antagonism
    P W Radke
    Medical Clinic I, RWTH University Hospital, Pauwelsstrasse 30, D 52057 Aachen, Germany
    J Invasive Cardiol 11:679-81. 1999
    ....
  9. ncbi request reprint Infectious agents in coronary lesions obtained by endatherectomy: pattern of distribution, coinfection, and clinical findings
    P W Radke
    Medical Clinic I, RWTH University Hospital, Aachen, Germany
    Coron Artery Dis 12:1-6. 2001
    ..The patterns of distribution within coronary lesions and possible coinfections of these pathogens in the coronary vasculature had not previously been evaluated...
  10. ncbi request reprint Evaluation of the SOFA score: a single-center experience of a medical intensive care unit in 303 consecutive patients with predominantly cardiovascular disorders. Sequential Organ Failure Assessment
    U Janssens
    Medical Clinic I, University Hospital of Aachen, Germany
    Intensive Care Med 26:1037-45. 2000
    ....
  11. pmc Superiority of sirolimus eluting stent compared with intracoronary beta radiation for treatment of in-stent restenosis: a matched comparison
    E Iofina
    Medical Clinic I, University RWTH Aachen, Germany
    Heart 91:1584-9. 2005
    ..To compare acute and follow up clinical and angiographic results after treatment of in-stent restenosis (ISR) by sirolimus eluting stents (SES) with results obtained after intracoronary radiation therapy (IRT)...
  12. ncbi request reprint Thrombosis in Behcet's disease: report of a case followed by a systematic review using the methodology of evidence-based medicine
    P W Radke
    Medical Clinic 1, RWTH University Hospital, Aachen, Germany
    J Thromb Thrombolysis 11:137-41. 2001
    ..Behcet's disease (BD) is a rare systemic inflammatory disease of unknown aetiology with a variety of organ manifestations...
  13. ncbi request reprint Insufficient tissue ablation by rotational atherectomy leads to worse long-term results in comparison with balloon angioplasty alone for the treatment of diffuse in-stent restenosis: insights from the intravascular ultrasound substudy of the ARTIST random
    Philipp K Haager
    Medizinische Klinik I, Universitätsklinik Aachen, Aachen, Germany
    Catheter Cardiovasc Interv 60:25-31. 2003
    ..Neointimal ablation by RA has only minor effects. Low-pressure PTCA does not prevent recurrent tissue growth and failed for treatment of ISR due to insufficient stent expansion...
  14. ncbi request reprint Impact of the metabolic syndrome on angiographic and clinical events after coronary intervention using bare-metal or sirolimus-eluting stents
    Rainer Hoffmann
    Medical Clinic I, University RWTH Aachen, Aachen, Germany
    Am J Cardiol 100:1347-52. 2007
    ..In contrast, DM is associated with significantly increased event rates...
  15. ncbi request reprint Rational use of drug-eluting stents: a comparison of different policies
    Marko Remmel
    Medical Clinic II, University of Schleswig Holstein, Campus Lubeck, Lubeck, Germany
    Crit Pathw Cardiol 6:85-9. 2007
    ..Such algorithm provides the rational for preprocedural risk stratification and efficient use of resources...
  16. ncbi request reprint Association between arterial pressure and coronary artery calcification
    Björn Mayer
    Medizinische Klinik II, Universitatsklinik Schleswig Holstein, Campus Lubeck, Lubeck, Germany
    J Hypertens 25:1731-8. 2007
    ..This study investigates conditions affecting CAC severity in patients with coronary artery disease (CAD) undergoing coronary angiography...
  17. ncbi request reprint Apical and midventricular transient left ventricular dysfunction syndrome (tako-tsubo cardiomyopathy): frequency, mechanisms, and prognosis
    Volkhard Kurowski
    Medical Clinic II, University Hospital Schleswig Holstein, Campus Lubeck, Ratzeburger Allee 160, D 23538 Lubeck, Germany
    Chest 132:809-16. 2007
    ..The frequency and potential differences between patients with apical ("typical") and midventricular ("atypical") ballooning have not been described...
  18. ncbi request reprint Comparison of coronary restenosis rates in matched patients with versus without diabetes mellitus
    Peter W Radke
    Medical Clinic II, University of Schleswig Holstein, Campus Lubeck, Lubeck, Germany
    Am J Cardiol 98:1218-22. 2006
    ..Mechanistically, inferior procedural results, as well as exaggerated neointimal proliferation, are, quantitatively, equally important in this process...
  19. ncbi request reprint A double-blind, randomized, placebo-controlled multicenter clinical trial to evaluate the effects of the angiotensin II receptor blocker candesartan cilexetil on intimal hyperplasia after coronary stent implantation
    Peter W Radke
    Medical Clinic I, RWTH University Hospital Aachen, Aachen, Germany
    Am Heart J 152:761.e1-6. 2006
    ..The AACHEN trial was a double-blind, randomized, placebo-controlled clinical multicenter trial to evaluate the effects of candesartan cilexetil on intimal hyperplasia after coronary stent implantation...
  20. ncbi request reprint Evaluation of the porcine ameroid constrictor model of myocardial ischemia for therapeutic angiogenesis studies
    Peter W Radke
    Department of Gene Therapy, National Heart and Lung Institute, Faculty of Medicine, Imperial College, London, UK
    Endothelium 13:25-33. 2006
    ..Angiographic assessment of the degree of coronary collateralization, however, is not associated with myocardial blood flow or function and should not be used as a primary outcome measure of therapeutic angiogenesis studies in this model...
  21. doi request reprint Mild therapeutic hypothermia in patients after out-of-hospital cardiac arrest due to acute ST-segment elevation myocardial infarction undergoing immediate percutaneous coronary intervention
    Sebastian Wolfrum
    Medical Clinic II, University of Schleswig Holstein, Campus Lubeck, Lubeck, Germany
    Crit Care Med 36:1780-6. 2008
    ..This study investigated whether a combination of MTH with primary percutaneous coronary intervention (PCI) is feasible, safe, and potentially beneficial in patients after cardiac arrest due to acute myocardial infarction...
  22. ncbi request reprint Randomized comparison of direct stenting with predilatation followed by stenting on vessel trauma and restenosis
    Rainer Hoffmann
    Medical Clinic I, University Hospital RWTH, Aachen, Germany
    Am Heart J 147:E13. 2004
    ..This study evaluated acute vessel trauma and acute and follow-up angiographic and intravascular ultrasound (IVUS) results after direct stenting in comparison to conventional stenting...
  23. ncbi request reprint Mechanisms of myocardial hypoperfusion during rotational atherectomy of de novo coronary artery lesions and stenosed coronary stents: insights from serial myocardial scintigraphy
    Karl Christian Koch
    Department of Cardiology Medizinische Klinik I, University Hospital, RWTH Aachen, Pauwelstrasse 30, D 52057 Aachen, Germany
    J Nucl Cardiol 9:304-11. 2002
    ..This study compares the incidence, extent, and severity of perfusion defects induced by rotablation of de novo coronary lesions with rotablation of in-stent restenosis...
  24. ncbi request reprint Intravascular ultrasonic comparative analysis of degree of intimal hyperplasia produced by four different stents in the coronary arteries
    Rainer Hoffmann
    Medical Clinic I, University RWTH Aachen, Aachen, Germany
    Am J Cardiol 94:1548-50. 2004
    ..048 and p <0.001), respectively, whereas mean intimal hyperplasia thickness treated with dexamethasone-eluting stents was similar to those lesions treated with bare metal stents...
  25. ncbi request reprint Sirolimus- and paclitaxel-eluting stents in comparison with balloon angioplasty for treatment of in-stent restenosis
    Ekaterina Iofina
    Medical Clinic I, University RWTH Aachen, Aachen, Germany
    Catheter Cardiovasc Interv 64:28-34. 2005
    ..The combination of improved acute gain and reduced late loss results in a significantly improved angiographic follow-up result in comparison with PTCA...
  26. ncbi request reprint Association of C-reactive protein and myocardial perfusion in patients with ST-elevation acute myocardial infarction
    Rainer Hoffmann
    Medical Clinic I, University Hospital RWTH Aachen, Pauwelsstrasse 30, 52057 Aachen, Germany
    Atherosclerosis 186:177-83. 2006
    ..The combination of clinical data, myocardial reperfusion levels after primary angioplasty for AMI and admission CRP increases the predictive value for subsequent survival...
  27. ncbi request reprint The efficacy of a 'master switch gene' HIF-1alpha in a porcine model of chronic myocardial ischaemia
    Amanda Heinl-Green
    Department of Gene Therapy, Faculty of Medicine, The National Heart and Lung Institute, Imperial College London, Manresa Road, London SW3 6LR, UK
    Eur Heart J 26:1327-32. 2005
    ..Therapeutic angiogenesis is a potential new treatment for patients unsuitable for conventional revascularization strategies. We investigated angiogenesis via a 'master switch gene' hypoxia inducible factor (HIF-1alpha)...
  28. ncbi request reprint Vascular oligonucleotide transfer facilitated by a polymer-coated stent
    Peter W Radke
    Department of Gene Therapy, National Heart and Lung Institute, Faculty of Medicine, Imperial College London, SW3 6LR, UK
    Hum Gene Ther 16:734-40. 2005
    ..Rapid intravascular release of ODN before implantation and potential vascular barriers for gene transfer are most likely responsible for the currently unsatisfactory in vivo release kinetics...
  29. doi request reprint Glucose-lowering therapy after myocardial infarction: more questions than answers
    Peter W Radke
    Eur Heart J 29:141-3. 2008
    ..Alselmino et al., on page 177..
  30. ncbi request reprint Drugs in interventional cardiology
    Peter W Radke
    Curr Pharm Des 14:1151. 2008
  31. ncbi request reprint Anticoagulation in patients with heparin-induced thrombocytopenia undergoing percutaneous coronary angiography and interventions
    Alexander Joost
    Medizinische Klinik II, Universitat zu Lubeck, Lubeck, Germany
    Curr Pharm Des 14:1176-85. 2008
    ..This review will provide current pathophysiological insights of HIT as well as contemporary alternative anticoagulant strategies during PCI in patients with or at risk of HIT...
  32. ncbi request reprint Thienopyridines in percutaneous coronary interventions: standard procedures and high risk subsets
    Peter W Radke
    Medical Clinic II, University of Schleswig Holstein, Campus Lubeck, Ratzeburger Allee 160, D 23538 Lubeck, Germany
    Curr Pharm Des 12:1281-6. 2006
    ..Furthermore, clinically relevant issues that are not clearly covered by recommendations or guidelines like thienopyridines after coronary interventions in patients on chronic oral anticoagulation are also addressed...