L Radbruch

Summary

Affiliation: University Hospital
Country: Germany

Publications

  1. doi Long-term tolerability, efficacy and acceptability of fentanyl pectin nasal spray for breakthrough cancer pain
    Lukas Radbruch
    Klinik für Palliativmedizin, Universitatsklinikum Bonn, Sigmund Freud Str 25, 53127 Bonn, Germany
    Support Care Cancer 20:565-73. 2012
  2. pmc Outcome indicators in palliative care--how to assess quality and success. Focus group and nominal group technique in Germany
    Tania Pastrana
    Department of Palliative Medicine, RWTH Aachen University, Aachen, Germany
    Support Care Cancer 18:859-68. 2010
  3. pmc Paediatric palliative home care by general paediatricians: a multimethod study on perceived barriers and incentives
    Saskia Jünger
    Department of Palliative Medicine, RWTH Aachen University Hospital, Pauwelsstrasse 30, 52057 Aachen, Germany
    BMC Palliat Care 9:11. 2010
  4. pmc Barriers and needs in paediatric palliative home care in Germany: a qualitative interview study with professional experts
    Saskia Jünger
    Department of Palliative Medicine, RWTH Aachen University Hospital, Pauwelsstrasse 30, 52057 Aachen, Germany
    BMC Palliat Care 9:10. 2010
  5. ncbi [Needs and expectations of patients during pain treatment]
    L Radbruch
    Klinik für Palliativmedizin, Universitatsklinikum Aachen
    Dtsch Med Wochenschr 133:S29-31. 2008
  6. ncbi [What is the profile of palliative care in Germany. Results of a representative survey]
    L Radbruch
    Klinik für Palliativmedizin, Universitatsklinikum Aachen
    Schmerz 18:179-88. 2004
  7. ncbi [Review of cannabinoids in the treatment of nausea and vomiting]
    L Radbruch
    Klinik für Palliativmedizin, Universitatsklinikum Aachen
    Schmerz 18:306-10. 2004
  8. doi Fatigue in palliative care patients -- an EAPC approach
    Lukas Radbruch
    Department of Palliative Medicine, RWTH Aachen University, Aachen, Germany
    Palliat Med 22:13-32. 2008
  9. ncbi Emerging analgesics in cancer pain management
    Lukas Radbruch
    University of Aachen, Department of Palliative Medicine, Pauwelsstrasse 30, 52074 Aachen, Germany
    Expert Opin Emerg Drugs 10:151-71. 2005
  10. ncbi [Palliative pain therapy, cannabinoids]
    L Radbruch
    Klinik für Palliativmedizin, RWTH Aachen
    Internist (Berl) 46:1105-14. 2005

Collaborators

Detail Information

Publications55

  1. doi Long-term tolerability, efficacy and acceptability of fentanyl pectin nasal spray for breakthrough cancer pain
    Lukas Radbruch
    Klinik für Palliativmedizin, Universitatsklinikum Bonn, Sigmund Freud Str 25, 53127 Bonn, Germany
    Support Care Cancer 20:565-73. 2012
    ..This study assessed the long-term tolerability, acceptability and consistency of effect of FPNS in patients with BTCP...
  2. pmc Outcome indicators in palliative care--how to assess quality and success. Focus group and nominal group technique in Germany
    Tania Pastrana
    Department of Palliative Medicine, RWTH Aachen University, Aachen, Germany
    Support Care Cancer 18:859-68. 2010
    ..The aim of this study is to investigate important dimensions and indicators for assessment and evaluation of palliative care from the perspective of multi-disciplinary German experts working over years in the field of palliative care...
  3. pmc Paediatric palliative home care by general paediatricians: a multimethod study on perceived barriers and incentives
    Saskia Jünger
    Department of Palliative Medicine, RWTH Aachen University Hospital, Pauwelsstrasse 30, 52057 Aachen, Germany
    BMC Palliat Care 9:11. 2010
    ..The aim of this study was therefore to examine potential barriers, incentives, and the professional self-image of general paediatricians with regard to paediatric palliative care...
  4. pmc Barriers and needs in paediatric palliative home care in Germany: a qualitative interview study with professional experts
    Saskia Jünger
    Department of Palliative Medicine, RWTH Aachen University Hospital, Pauwelsstrasse 30, 52057 Aachen, Germany
    BMC Palliat Care 9:10. 2010
    ..As part of the research, barriers and needs with respect to paediatric palliative home care in the target region were explored...
  5. ncbi [Needs and expectations of patients during pain treatment]
    L Radbruch
    Klinik für Palliativmedizin, Universitatsklinikum Aachen
    Dtsch Med Wochenschr 133:S29-31. 2008
    ..In consequence we find that patients who have done poorly in driving tests will have difficulties also in other areas, just as the opposite may be true...
  6. ncbi [What is the profile of palliative care in Germany. Results of a representative survey]
    L Radbruch
    Klinik für Palliativmedizin, Universitatsklinikum Aachen
    Schmerz 18:179-88. 2004
    ..The core documentation does however furnish data from a representative sample of in-patient palliative care in Germany, which can be used as a comparative data pool for other studies and quality assurance measures...
  7. ncbi [Review of cannabinoids in the treatment of nausea and vomiting]
    L Radbruch
    Klinik für Palliativmedizin, Universitatsklinikum Aachen
    Schmerz 18:306-10. 2004
    ..For patients who cannot be adequately treated with conventional antiemetic agents, cannabinoids can represent a valuable adjunct to the antiemetic regimen...
  8. doi Fatigue in palliative care patients -- an EAPC approach
    Lukas Radbruch
    Department of Palliative Medicine, RWTH Aachen University, Aachen, Germany
    Palliat Med 22:13-32. 2008
    ..Identification of the time point, where treatment of fatigue is no longer indicated is important to alleviate distress at the end of life...
  9. ncbi Emerging analgesics in cancer pain management
    Lukas Radbruch
    University of Aachen, Department of Palliative Medicine, Pauwelsstrasse 30, 52074 Aachen, Germany
    Expert Opin Emerg Drugs 10:151-71. 2005
    ....
  10. ncbi [Palliative pain therapy, cannabinoids]
    L Radbruch
    Klinik für Palliativmedizin, RWTH Aachen
    Internist (Berl) 46:1105-14. 2005
    ..Cannabinoids such as tetrahydrocannabinol offer a valuable add-on option for cancer patients with refractory pain, spasticity, nausea or appetite loss...
  11. ncbi Clinical experience with transdermal fentanyl for the treatment of cancer pain in Germany
    Lukas Radbruch
    Department of Palliative Medicine, University Hospital Aachen, Aachen, Germany
    Keio J Med 53:23-9. 2004
    ..Transdermal fentanyl has become a wellknown and frequently used opioid in the treatment of chronic cancer and non-cancer pain in Germany...
  12. ncbi [A review of side effects and complications with cannabinoid treatment]
    L Radbruch
    Klinik für Palliativmedizin, Universitatsklinikum Aachen
    Schmerz 17:274-9. 2003
    ..Life-threatening complications are very rare and were not reported after use of cannabinoids for medical indications. Cannabinoids are contraindicated during pregnancy or for patients with a history of cardiac ischemias...
  13. ncbi What are the problems in palliative care? Results from a representative survey
    Lukas Radbruch
    Department of Palliative Medicine, University Hospital, Pauwelsstr 30, 52074, Aachen, Germany
    Support Care Cancer 11:442-51. 2003
    ..Using the categories identified in this study, checklists were constructed and included in the documentation forms that are currently used for the core documentation project...
  14. doi [Problems and deficits in the transition from inpatient and outpatient care of cancer patients. A qualitative analysis]
    S Stiel
    Klinik für Palliativmedizin, Universitätsklinikum RWTH Aachen, Pauwelsstr 30, 52074 Aachen
    Schmerz 23:510-7. 2009
    ..The project was initiated by the Public Health Department of the City of Aachen and was carried out with cooperation from all hospitals in the urban areas...
  15. doi [Experiences of cancer patients with breakthrough pain and pharmacological treatments]
    L Bertram
    Klinik für Palliativmedizin, RWTH Aachen, Pauwelsstr 30, 52074 Aachen, Deutschland
    Schmerz 24:605-12. 2010
    ..This study explores the patients' perception of breakthrough pain, their experiences with existing therapeutic regimens and their expectations regarding an ideal breakthrough pain medication...
  16. doi [A wish to hasten death : what is behind it]
    S Stiel
    Klinik für Palliativmedizin, Universitätsklinikum der RWTH Aachen, Pauwelsstr 30, 52074, Aachen, Deutschland
    Schmerz 24:177-89. 2010
    ....
  17. doi [Evaluation of 12 pilot projects to improve outpatient palliative care]
    G Schmidt-Wolf
    Klinik für Palliativmedizin, Universitatsklinikum Bonn
    Dtsch Med Wochenschr 138:2585-91. 2013
    ..The 12 regional pilot projects funded with the aim to improve outpatient palliative care in different models and different frameworks were concurrently monitored and evaluated...
  18. doi [Validation of the new version of the minimal documentation system (MIDOS) for patients in palliative care : the German version of the edmonton symptom assessment scale (ESAS)]
    S Stiel
    Klinik für Palliativmedizin, RWTH Aachen, Pauwelsstr 30, 52074 Aachen, Deutschland
    Schmerz 24:596-604. 2010
    ....
  19. pmc Evaluation and comparison of two prognostic scores and the physicians' estimate of survival in terminally ill patients
    S Stiel
    Department of Palliative Medicine, RWTH Aachen University, Pauwelsstrasse 30, 52074 Aachen, Germany
    Support Care Cancer 18:43-9. 2010
    ....
  20. doi A matter of definition--key elements identified in a discourse analysis of definitions of palliative care
    T Pastrana
    Department of Palliative Medicine, RWTH Aachen University, Aachen, Germany
    Palliat Med 22:222-32. 2008
    ..Our study confirms the importance of semantic and ethical influences on palliative care that should be considered in future research on semantics in different languages...
  21. ncbi [Indications and use of benzodiazepines in a palliative care unit]
    S Stiel
    Klinik für Palliativmedizin, Universitätsklinikum RWTH Aachen, Pauwelsstr 30, 52074 Aachen, Deutschland
    Schmerz 22:665-71. 2008
    ..Incidence of palliative sedation has been reported to vary between 5-52% of all patients in a palliative care setting in several studies...
  22. ncbi Intravenous versus subcutaneous morphine titration in patients with persisting exacerbation of cancer pain
    F Elsner
    Department of Palliative Medicine, RWTH Aachen University, Pauwelsstrasse 30, 52074 Aachen, Germany
    J Palliat Med 8:743-50. 2005
    ..Sometimes even fast help is needed and then optimally performed by intravenous application (IVA) of immediate-release (IR) opioids. This IVA, however, may only be performed by physicians in Germany...
  23. doi [Methods and development of therapy recommendations for symptom control in palliative medicine]
    L Radbruch
    Klinik für Palliativmedizin, Universitatsklinikum Bonn, Sigmund Freud Str 25, 53127, Bonn, Deutschland
    Schmerz 26:475-80. 2012
    ..The English full text version of this article will be available in SpringerLink as of November 2012 (under "Supplemental")...
  24. doi [Glucocorticoids and androgens for treatment of tiredness and weakness in palliative care patients : a systematic review]
    A Thiem
    Klinik für Palliativmedizin, Universitatsklinikum Bonn, Sigmund Freud Str 25, 53127, Bonn, Deutschland
    Schmerz 26:550-67. 2012
    ..Glucocorticoids and androgens are habitually mentioned drugs for treatment. In this review evidence for glucocorticoids and androgens for these indications in palliative care patients are presented...
  25. ncbi [Efficacy of opioid analgesia at the superior cervical ganglion in neuropathic head and facial pain]
    F Elsner
    Klinik für Palliativmedizin, Universitätsklinikum der RWTH Aachen
    Schmerz 20:268-72, 274-6. 2006
    ..The other patients reported often only minimal residual pain or a decrease of pain severity and duration. According to these results, GLOA at the SCG can represent a suitable and simple treatment option for neuropathic facial pain...
  26. ncbi [Problems and deficits in the transition from inpatient to outpatient care of cancer patients]
    Stephanie Stiel
    Klinik für Palliativmedizin, Universitätsklinikum RWTH Aachen
    Z Evid Fortbild Qual Gesundhwes 103:461-6. 2009
    ..Initiated by the Public Health Department of the City of Aachen problems and deficits in the transition from hospital-based to outpatient care of cancer patients were evaluated...
  27. doi Disparities in the contribution of low- and middle-income countries to palliative care research
    Tania Pastrana
    Department of Palliative Medicine, RWTH Aachen University, 52074 Aachen, Germany
    J Pain Symptom Manage 39:54-68. 2010
    ..In this context, the understanding of specific social and cultural needs is fundamental to the development of appropriate health policy and clinical practice concerning palliative and end-of-life care...
  28. doi The use of Grounded theory in palliative care: methodological challenges and strategies
    Stephanie Stiel
    Department of Palliative Medicine, RWTH Aachen University, Aachen, Germany
    J Palliat Med 13:997-1003. 2010
    ..This article describes the use and adaptation of a qualitative research methodology in a palliative care setting...
  29. doi [Pain management in palliative care. Current aspects of medicinal therapy]
    H Cuhls
    Klinik und Poliklinik für Palliativmedizin, Universitatsklinikum Bonn, Sigmund Freud Str 25, 53127, Bonn
    Internist (Berl) 54:254, 256-62. 2013
    ..However, pain treatment should always address the psychological, social and spiritual demands of the patient...
  30. doi End-of-life research on patients' attitudes in Germany: a feasibility study
    R Voltz
    Department of Palliative Medicine, University Hospital, Cologne, Germany
    Support Care Cancer 18:317-20. 2010
    ..So far, hardly any experience exists whether end-of-life research on patients' attitudes towards hastened death in Germany is feasible and how it is perceived by the patients...
  31. ncbi Validation of the German version of the brief fatigue inventory
    Lukas Radbruch
    Department of Palliative Medicine, University of Aachen, Aachen, Germany
    J Pain Symptom Manage 25:449-58. 2003
    ..93 and the impairment mean scores of 0.87. In conclusion, we found the German version of the BFI to be reliable and valid for cancer and noncancer patients. Minor differences were seen in the validation compared to the original version...
  32. ncbi Criteria for successful multiprofessional cooperation in palliative care teams
    S Junger
    Aachen University, Aachen, Germany
    Palliat Med 21:347-54. 2007
    ..Team work is considered a central component of palliative care. Within this comparatively young field of medicine, the emergence of new institutions (eg, palliative care units) highlights the challenge of establishing a completely new team...
  33. ncbi [Treatment discontinuation and obligation to treat: an extended model for the decision-making process]
    R Joppich
    Klinik für Palliativmedizin, Universitatsklinikum, Pauwelsstr 30, 52074, Aachen, Germany
    Anaesthesist 55:502-14. 2006
    ..Algorithms can be helpful to illustrate the steps in a decision-making process and thus support medical staff in situations of difficult medical decisions...
  34. ncbi Treatment of fatigue: modafinil, methylphenidate, and goals of care
    Heike Reineke-Bracke
    Department of Palliative Care, RWTH Aachen, Aachen, Germany
    J Palliat Med 9:1210-4. 2006
  35. ncbi Pharmacological treatments for fatigue associated with palliative care
    Vera Peuckmann
    Medical Faculty RWTH, Universitatsklinikum Aachen, Hauptgebäude, Aufzug B 1, Etage 1, Flur 1, Raum Nr 5, Pauwelsstrase 30, Aachen, Germany, 52074
    Cochrane Database Syst Rev 11:CD006788. 2010
    ..Further complicating issues are its multidimensionality, subjective nature, and lack of a consensus definition of fatigue. Pathophysiology is not fully understood and evidence-based treatment approaches are needed...
  36. doi [Evaluation of the need for communication training of ophthalmologists for gaining telephone consent for cornea donation]
    S Stiel
    Klinik für Palliativmedizin, Universitatsklinikum, RWTH Aachen, Pauwelsstrasse 30, 52074, Aachen, Deutschland
    Ophthalmologe 108:151-5. 2011
    ..This study assesses the need and expectations of physicians towards communication training in preparation for their task...
  37. ncbi Episodic (breakthrough) pain: consensus conference of an expert working group of the European Association for Palliative Care
    Sebastiano Mercadante
    Pain Relief and Palliative Care Unit, La Maddalena Cancer Center, Palermo, Italy
    Cancer 94:832-9. 2002
    ..The wide differences in estimation of incidence reported in literature are probably because of different settings and meanings attributed to the definition of breakthrough pain...
  38. ncbi What is palliative care in Germany? Results from a representative survey
    Lukas Radbruch
    Pain Clinic, Department of Anesthesiology, University of Cologne, Cologne, Germany
    J Pain Symptom Manage 23:471-83. 2002
    ..However, common documentation instruments may be the first step towards an interdisciplinary discussion on aims and methods in palliative care...
  39. ncbi Germany: Cancer pain and palliative care--current situation
    Lukas Radbruch
    Pain Clinic, Department of Anesthesiology, University of Cologne, Cologne, Germany
    J Pain Symptom Manage 24:183-7. 2002
  40. ncbi Patients' associations with regard to analgesic drugs and their forms for application -- a pilot study
    Lukas Radbruch
    Department of Anaesthesiology, University of Cologne, Cologne, Germany
    Support Care Cancer 10:480-5. 2002
    ..The results may give a first hint that minor cultural differences even between western European countries may lead to major differences in prescribing habits and treatment regimens...
  41. ncbi Driving ability under long-term treatment with transdermal fentanyl
    Rainer Sabatowski
    Department of Anesthesiology, University of Cologne, Cologne, Germany
    J Pain Symptom Manage 25:38-47. 2003
    ..The threshold for fitness to drive as defined by German law did not differ significantly between the groups...
  42. ncbi Validation and clinical application of the german version of the palliative care outcome scale
    Claudia Bausewein
    Interdisciplinary Center for Palliative Medicine, University of Munich, Munich, Germany
    J Pain Symptom Manage 30:51-62. 2005
    ..Thus, the German version of the POS is well accepted by patients and staff and appears to be valid, although there are some areas where the scale would benefit from expansion to more closely capture staff and patient concerns...
  43. ncbi Assessing cognitive and psychomotor performance under long-term treatment with transdermal buprenorphine in chronic noncancer pain patients
    Oguzhan Dagtekin
    Department of Anesthesiology, University of Cologne, Cologne, Germany
    Anesth Analg 105:1442-8, table of contents. 2007
    ..Several studies have demonstrated the impact of opioid therapy on psychomotor performance and cognition, but there are no data about the effect of long-term treatment with transdermal buprenorphine on driving ability...
  44. ncbi [Palliative medicine: how can the family physician help, when recovery is not possible? (interview by Christine Vetter)]
    Lukas Radbruch
    MMW Fortschr Med 146:10. 2004
  45. ncbi [Euthanasia and the principle of the double action]
    Lukas Radbruch
    Wien Klin Wochenschr 114:878-9; author reply 879-80. 2002
  46. ncbi Drugs in palliative care: results from a representative survey in Germany
    Friedemann Nauck
    Department of Anaesthesiology and Palliative Medicine, Malteser Hospital, University Bonn, Bonn, Germany
    Palliat Med 18:100-7. 2004
    ..Age and sex-related differences in drug therapy were seen, and more research is needed to recognize possible undertreatment of symptoms in subgroups of patients, e.g., treatment of depression in older or male patients...
  47. doi Symptom assessment in palliative care: a need for international collaboration
    Stein Kaasa
    Pain and Palliation Research Group, Department of Cancer Research and Molecular Medicine, Faculty of Medicine, Trondheim, Norway
    J Clin Oncol 26:3867-73. 2008
    ..In the future, patients may find that a combination of a face-to-face interview plus a transfer of information of subjective symptoms by electronic means will optimize treatment...
  48. ncbi [Quality assurance in palliative medicine--results of the core documentation of 1999-2002]
    Gabriele Lindena
    Clinical Analysis, Research and Application, CLARA Kleinmachnow
    Z Arztl Fortbild Qualitatssich 99:555-65. 2005
    ..The results of the previous evaluations have enabled the development of a standard documentation. The continuous application of such a standard documentation will prove the quality improvement and development of the participating units...
  49. ncbi The Budapest Commitments: setting the goals a joint initiative by the European Association for Palliative Care, the International Association for Hospice and Palliative Care and Help the Hospices
    Lukas Radbruch
    Palliat Med 21:269-71. 2007
  50. ncbi [Internet-based conjoint analysis with the example of medical networks]
    Norbert Schmeisser
    Institut und Poliklinik für Psychosomatik und Psychotherapie, Klinikum der Universität Köln
    Z Arztl Fortbild Qualitatssich 97:727-32. 2003
    ....
  51. ncbi Patient-controlled analgesia with intravenous L-methadone in a child with cancer pain refractory to high-dose morphine
    Rainer Sabatowski
    J Pain Symptom Manage 23:3-5. 2002
  52. doi Palliative care research--priorities and the way forward
    Stein Kaasa
    Department of Cancer Research and Molecular Medicine, Faculty of Medicine, Trondheim, Norway
    Eur J Cancer 44:1175-9. 2008
    ..Since the majority of palliative care patients come from oncology, it is important to establish a close collaboration between these two disciplines...
  53. ncbi Encapsulation of an intrathecal catheter
    Jan Gaertner
    Department of Anaesthesiology, University of Cologne, 50924 Cologne, Germany
    Pain 103:217-20. 2003
    ..After antibiotic therapy and removal of the catheter, morphine was administered intravenously with a one to one conversion ratio...
  54. ncbi Pain assessment tools: is the content appropriate for use in palliative care?
    Jacob Chr Hølen
    Pain and Palliation Research Group, Department of Cancer Research and Molecular Medicine, Faculty of Medicine, Norwegian University of Science and Technology, Trondheim, Norway
    J Pain Symptom Manage 32:567-80. 2006
    ..This might reduce compliance and threaten the validity of the assessment. New tools should reflect the clinical relevance of different dimensions and be user-friendly...
  55. ncbi Pain measurement tools and methods in clinical research in palliative care: recommendations of an Expert Working Group of the European Association of Palliative Care
    Augusto Caraceni
    Rehabilitation and Palliative Care Unit, National Cancer Institute of Milan, Milan, Italy
    J Pain Symptom Manage 23:239-55. 2002
    ..Special population requirements specific of clinical situations encountered in palliative care (elderly, terminal, cognitively impaired patients, pediatric patients) are also considered...