Ildiko Racz

Summary

Affiliation: University of Bonn
Country: Germany

Publications

  1. pmc The opioid peptides enkephalin and beta-endorphin in alcohol dependence
    Ildiko Racz
    Institute of Molecular Psychiatry, Life and Brain Center, University of Bonn, Bonn, Germany
    Biol Psychiatry 64:989-97. 2008
  2. doi request reprint Control of hormonal stress reactivity by the endogenous opioid system
    Andras Bilkei-Gorzo
    Institute of Molecular Psychiatry, University of Bonn, Sigmund Freud Street 25, 53105 Bonn, Germany
    Psychoneuroendocrinology 33:425-36. 2008
  3. pmc Interferon-gamma is a critical modulator of CB(2) cannabinoid receptor signaling during neuropathic pain
    Ildiko Racz
    Institute of Molecular Psychiatry and Department of Psychiatry, University of Bonn, 53105 Bonn, Germany
    J Neurosci 28:12136-45. 2008
  4. ncbi request reprint A critical role for the cannabinoid CB1 receptors in alcohol dependence and stress-stimulated ethanol drinking
    Ildiko Racz
    Laboratory of Molecular Neurobiology, Department of Psychiatry, University of Bonn, 53105 Bonn, Germany
    J Neurosci 23:2453-8. 2003
  5. doi request reprint Long-term ethanol effects on acute stress responses: modulation by dynorphin
    Ildiko Racz
    Institute of Molecular Psychiatry, University of Bonn, Bonn, Germany
    Addict Biol 18:678-88. 2013
  6. doi request reprint Quantitative trait loci contributing to physiological and behavioural ethanol responses after acute and chronic treatment
    Eva Drews
    Life and Brain GmbH, Bonn, Germany
    Int J Neuropsychopharmacol 13:155-69. 2010
  7. ncbi request reprint Behavioral phenotype of pre-proenkephalin-deficient mice on diverse congenic backgrounds
    Andras Bilkei-Gorzo
    Laboratory of Molecular Neurobiology, Clinic of Psychiatry, Neurocenter, University of Bonn, Sigmund Freud Strasse 25, 53105 Bonn, Germany
    Psychopharmacology (Berl) 176:343-52. 2004
  8. doi request reprint Modulation of the CRH system by substance P/NKA in an animal model of depression
    Pamela Frisch
    Institute of Molecular Psychiatry, University of Bonn, Sigmund Freud Str 25, 53127 Bonn, Germany
    Behav Brain Res 213:103-8. 2010
  9. ncbi request reprint A common genetic predisposition to stress sensitivity and stress-induced nicotine craving
    Andras Bilkei-Gorzo
    Institute of Molecular Psychiatry, Life and Brain Center, University of Bonn, Bonn, Germany
    Biol Psychiatry 63:164-71. 2008
  10. ncbi request reprint Visceral, inflammatory and neuropathic pain in glycine receptor alpha 3-deficient mice
    Ildiko Racz
    Laboratory of Molecular Neurobiology, Department of Psychiatry, University of Bonn, Bonn, Germany
    Neuroreport 16:2025-8. 2005

Collaborators

Detail Information

Publications16

  1. pmc The opioid peptides enkephalin and beta-endorphin in alcohol dependence
    Ildiko Racz
    Institute of Molecular Psychiatry, Life and Brain Center, University of Bonn, Bonn, Germany
    Biol Psychiatry 64:989-97. 2008
    ..Because stress is an important factor contributing to drug dependence and relapse, we have now studied ethanol preference in enkephalin- and beta-endorphin-deficient mice under baseline conditions and after stress exposure...
  2. doi request reprint Control of hormonal stress reactivity by the endogenous opioid system
    Andras Bilkei-Gorzo
    Institute of Molecular Psychiatry, University of Bonn, Sigmund Freud Street 25, 53105 Bonn, Germany
    Psychoneuroendocrinology 33:425-36. 2008
    ..These results demonstrate an important role on the endogenous opioid system in the integration of behavioral and hormonal stress responses...
  3. pmc Interferon-gamma is a critical modulator of CB(2) cannabinoid receptor signaling during neuropathic pain
    Ildiko Racz
    Institute of Molecular Psychiatry and Department of Psychiatry, University of Bonn, 53105 Bonn, Germany
    J Neurosci 28:12136-45. 2008
    ..These animals no longer show the enhanced manifestations of neuropathic pain observed in CB(2) knock-outs. These data clearly demonstrate that the CB(2) receptor-mediated control of neuropathic pain is IFN-gamma dependent...
  4. ncbi request reprint A critical role for the cannabinoid CB1 receptors in alcohol dependence and stress-stimulated ethanol drinking
    Ildiko Racz
    Laboratory of Molecular Neurobiology, Department of Psychiatry, University of Bonn, 53105 Bonn, Germany
    J Neurosci 23:2453-8. 2003
    ..These results reveal a critical role for the CB1 receptor in clinically important aspects of alcohol dependence and provide a rationale for the use of CB1 receptor antagonists in the treatment of alcohol addiction...
  5. doi request reprint Long-term ethanol effects on acute stress responses: modulation by dynorphin
    Ildiko Racz
    Institute of Molecular Psychiatry, University of Bonn, Bonn, Germany
    Addict Biol 18:678-88. 2013
    ..Together these data suggest that dynorphin plays an important role in the modulation of the brain stress-response systems after chronic ethanol exposure. ..
  6. doi request reprint Quantitative trait loci contributing to physiological and behavioural ethanol responses after acute and chronic treatment
    Eva Drews
    Life and Brain GmbH, Bonn, Germany
    Int J Neuropsychopharmacol 13:155-69. 2010
    ..Our analysis demonstrates that the various responses to ethanol are regulated by independent groups of genes...
  7. ncbi request reprint Behavioral phenotype of pre-proenkephalin-deficient mice on diverse congenic backgrounds
    Andras Bilkei-Gorzo
    Laboratory of Molecular Neurobiology, Clinic of Psychiatry, Neurocenter, University of Bonn, Sigmund Freud Strasse 25, 53105 Bonn, Germany
    Psychopharmacology (Berl) 176:343-52. 2004
    ..The phenotype of genetically modified animals is thought to result from an interaction of gene manipulation with the genetic background and environmental factors...
  8. doi request reprint Modulation of the CRH system by substance P/NKA in an animal model of depression
    Pamela Frisch
    Institute of Molecular Psychiatry, University of Bonn, Sigmund Freud Str 25, 53127 Bonn, Germany
    Behav Brain Res 213:103-8. 2010
    ..In the PVN, bulbectomized tac1(-/-) mice showed an elevated expression of CRHR1 and CRHR2. These results show that substance P/NKA is involved in modulating CRH signalling in an animal model of depression...
  9. ncbi request reprint A common genetic predisposition to stress sensitivity and stress-induced nicotine craving
    Andras Bilkei-Gorzo
    Institute of Molecular Psychiatry, Life and Brain Center, University of Bonn, Bonn, Germany
    Biol Psychiatry 63:164-71. 2008
    ..In this article, we have asked whether animals with a genetic predisposition to high or low stress responsivity differ in behaviors relevant to nicotine addiction, in particular stress-induced reinstatement of drug addiction...
  10. ncbi request reprint Visceral, inflammatory and neuropathic pain in glycine receptor alpha 3-deficient mice
    Ildiko Racz
    Laboratory of Molecular Neurobiology, Department of Psychiatry, University of Bonn, Bonn, Germany
    Neuroreport 16:2025-8. 2005
    ..Thus, alpha3-subunit of strychnine-sensitive glycine receptors is involved in the modulation of moderate inflammatory acetic acid-induced pain responses, but neither in formalin-induced pain nor in neuropathic pain...
  11. doi request reprint Anandamide effects on 5-HT(3) receptors in vivo
    Ildiko Racz
    Institute of Molecular Psychiatry, Life and Brain Center, University of Bonn, Sigmund Freud Strasse 25, Bonn, Germany
    Eur J Pharmacol 596:98-101. 2008
    ..We show that the cannabinoid receptor-independent anandamide analgesia, but not catalepsy, is completely blocked by ondansetron. Thus, 5-HT(3) receptors seem to be involved in cannabinoid analgesia...
  12. doi request reprint The transcription factor Smad-interacting protein 1 controls pain sensitivity via modulation of DRG neuron excitability
    Monika Jeub
    Department of Neurology, University of Bonn Medical Center, Bonn, Germany
    Pain 152:2384-98. 2011
    ..These data suggest that Sip1 controls the transduction properties of heat-sensitive primary sensory neurons and thus thermal pain sensitivity in a novel manner via coordinated changes in DRG-neuron voltage-gated ion channels...
  13. doi request reprint Role of cannabinoid receptors in alcoholic hepatic injury: steatosis and fibrogenesis are increased in CB2 receptor-deficient mice and decreased in CB1 receptor knockouts
    Jonel Trebicka
    Department of Internal Medicine I, University of Bonn, Bonn, Germany
    Liver Int 31:860-70. 2011
    ..To investigate the differences between CB(1) and CB(2) in the hepatic response to chronic alcohol intake, we examined CB knockout mice (CB(1)(-/-), CB(2)(-/-))...
  14. pmc Modulation of the Ca2+ conductance of nicotinic acetylcholine receptors by Lypd6
    Martin Darvas
    Institute of Molecular Psychiatry, University of Bonn, Bonn, Germany
    Eur Neuropsychopharmacol 19:670-81. 2009
    ..Taken together, Lypd6 seems to constitute a novel modulator of nAChRs that affects receptor function by selectively increasing Ca2+-influx through this ion channels...
  15. pmc Crucial role of CB(2) cannabinoid receptor in the regulation of central immune responses during neuropathic pain
    Ildiko Racz
    Institute of Molecular Psychiatry, University of Bonn, 53105 Bonn, Germany
    J Neurosci 28:12125-35. 2008
    ....
  16. ncbi request reprint Diminished anxiety- and depression-related behaviors in mice with selective deletion of the Tac1 gene
    Andras Bilkei-Gorzo
    Laboratory of Molecular Neurobiology, Department of Psychiatry, University of Bonn, 53105 Bonn, Germany
    J Neurosci 22:10046-52. 2002
    ..The tachykinin system therefore may play an important role in the regulation of emotional states and the development of anxiety disorders and depression...