C Rabe

Summary

Affiliation: University of Bonn
Country: Germany

Publications

  1. ncbi Outcome of patients with acute myeloid leukemia and pulmonary infiltrates requiring invasive mechanical ventilation-a retrospective analysis
    Christian Rabe
    Department of Medicine, University of Bonn, Germany
    J Crit Care 19:29-35. 2004
  2. doi Severe respiratory failure due to diffuse alveolar hemorrhage: clinical characteristics and outcome of intensive care
    Christian Rabe
    Medical ICU, Department of Internal Medicine I, University of Bonn, D 53105 Bonn, Germany
    J Crit Care 25:230-5. 2010
  3. ncbi [Clinical outcome of a cohort of 63 patients with hepatocellular carcinoma treated with octreotide]
    C Rabe
    Medizinische Klinik I, University of Bonn, Germany
    Z Gastroenterol 40:395-400. 2002
  4. ncbi Keeping central venous lines open: a prospective comparison of heparin, vitamin C and sodium chloride sealing solutions in medical patients
    Christian Rabe
    Department of Medicine I, University of Bonn, Sigmund Freud Strasse 25, 53105 Bonn, Germany
    Intensive Care Med 28:1172-6. 2002
  5. ncbi Biliary metal stents and air embolism: a note of caution
    C Rabe
    Department of Medicine I, University of Bonn, Bonn, Germany
    Endoscopy 38:648-50. 2006
  6. ncbi Does intubation really equal death in cirrhotic patients? Factors influencing outcome in patients with liver cirrhosis requiring mechanical ventilation
    Christian Rabe
    Department of Medicine I, University of Bonn, Sigmund Freud Strasse 25, 53105 Bonn, Germany
    Intensive Care Med 30:1564-71. 2004
  7. ncbi [Malaria in the emergency room. Results of the emergency treatment of 137 patients with symptomatic malaria]
    C Rabe
    Medizinische Klinik und Poliklinik I, Universitatskliniken Bonn
    Dtsch Med Wochenschr 130:145-9. 2005
  8. ncbi Acute hepatitis induced by an Aloe vera preparation: a case report
    Christian Rabe
    Department of Medicine, Evangelisches Krankenhaus, Koeln Kalk, Germany
    World J Gastroenterol 11:303-4. 2005
  9. ncbi An independent evaluation of modern prognostic scores in a central European cohort of 120 patients with hepatocellular carcinoma
    Christian Rabe
    Department of Medicine I, University of Bonn, Bonn, Germany
    Eur J Gastroenterol Hepatol 15:1305-15. 2003
  10. ncbi Effective angiostatic treatment in a murine metastatic and orthotopic hepatoma model
    Esther Raskopf
    Department of Internal Medicine I, University Hospital Bonn, Germany
    Hepatology 41:1233-40. 2005

Detail Information

Publications36

  1. ncbi Outcome of patients with acute myeloid leukemia and pulmonary infiltrates requiring invasive mechanical ventilation-a retrospective analysis
    Christian Rabe
    Department of Medicine, University of Bonn, Germany
    J Crit Care 19:29-35. 2004
    ..To assess the prognosis of patients with acute myeloid leukemia (AML) and pulmonary infiltrates requiring mechanical ventilation...
  2. doi Severe respiratory failure due to diffuse alveolar hemorrhage: clinical characteristics and outcome of intensive care
    Christian Rabe
    Medical ICU, Department of Internal Medicine I, University of Bonn, D 53105 Bonn, Germany
    J Crit Care 25:230-5. 2010
    ..The aim of this study was to characterize patients and report outcome of diffuse alveolar hemorrhage (DAH) requiring intensive care unit support...
  3. ncbi [Clinical outcome of a cohort of 63 patients with hepatocellular carcinoma treated with octreotide]
    C Rabe
    Medizinische Klinik I, University of Bonn, Germany
    Z Gastroenterol 40:395-400. 2002
    ..The patients' median survival was 9 months (Okuda stage I 16 months, stage II 9 months, stage III 4 months). In conclusion, octreotide treatment did not result in markedly prolonged survival in this retrospective series of 63 patients...
  4. ncbi Keeping central venous lines open: a prospective comparison of heparin, vitamin C and sodium chloride sealing solutions in medical patients
    Christian Rabe
    Department of Medicine I, University of Bonn, Sigmund Freud Strasse 25, 53105 Bonn, Germany
    Intensive Care Med 28:1172-6. 2002
    ..The present study was designed to test the effectiveness of this approach and to compare the efficiency of sealing solutions...
  5. ncbi Biliary metal stents and air embolism: a note of caution
    C Rabe
    Department of Medicine I, University of Bonn, Bonn, Germany
    Endoscopy 38:648-50. 2006
    ..It is likely that the large diameter of metal stents and the potential for these stents to lacerate venous structures facilitate the entry of air into the venous circulation, an event which may have life-threatening consequences...
  6. ncbi Does intubation really equal death in cirrhotic patients? Factors influencing outcome in patients with liver cirrhosis requiring mechanical ventilation
    Christian Rabe
    Department of Medicine I, University of Bonn, Sigmund Freud Strasse 25, 53105 Bonn, Germany
    Intensive Care Med 30:1564-71. 2004
    ..This study examines parameters both of chronic liver disease and of acute illness with regard to their influence on outcome in mechanically ventilated cirrhotic patients...
  7. ncbi [Malaria in the emergency room. Results of the emergency treatment of 137 patients with symptomatic malaria]
    C Rabe
    Medizinische Klinik und Poliklinik I, Universitatskliniken Bonn
    Dtsch Med Wochenschr 130:145-9. 2005
    ..To assess characteristics and outcome of emergency patients with acute malaria...
  8. ncbi Acute hepatitis induced by an Aloe vera preparation: a case report
    Christian Rabe
    Department of Medicine, Evangelisches Krankenhaus, Koeln Kalk, Germany
    World J Gastroenterol 11:303-4. 2005
    ..Aloe vera, plant extracts of Aloe barbadensis miller, is widely used in phytomedicine. The first case of acute hepatitis due to this compound was described...
  9. ncbi An independent evaluation of modern prognostic scores in a central European cohort of 120 patients with hepatocellular carcinoma
    Christian Rabe
    Department of Medicine I, University of Bonn, Bonn, Germany
    Eur J Gastroenterol Hepatol 15:1305-15. 2003
    ..We therefore tested the ability of several newer scores to predict survival in comparison to the Okuda score in a European cohort of HCC patients...
  10. ncbi Effective angiostatic treatment in a murine metastatic and orthotopic hepatoma model
    Esther Raskopf
    Department of Internal Medicine I, University Hospital Bonn, Germany
    Hepatology 41:1233-40. 2005
    ..The data support the value of VEGF blockade as an effective target for HCC treatment...
  11. ncbi Clinical characteristics and outcome of a cohort of 101 patients with hepatocellular carcinoma
    C Rabe
    Sigmund Freud Str. 25, D 53105 Bonn, Germany
    World J Gastroenterol 7:208-15. 2001
    ..Reflecting the high proportion of advanced stage tumors in our patients, the median survival was poor. Patients who received active therapy had a longer survival...
  12. ncbi Molecular mechanisms of hepatitis B virus-associated liver cancer
    C Rabe
    Department of Medicine I, University of Bonn, Germany
    Dig Dis 19:279-87. 2001
    ..They also alter mechanisms of apoptosis and interfere with nucleotide excision repair of damaged DNA. Together with an influence on cellular signaling, these mechanisms may favor the cell's clonal expansion...
  13. ncbi Cirrhotic patients with or without hepatocellular carcinoma harbour AFP-specific T-lymphocytes that can be activated in vitro by human alpha-fetoprotein
    P Hanke
    Dept of Medicine I, University of Bonn, Germany
    Scand J Gastroenterol 37:949-55. 2002
    ..A prerequisite for this approach is the possibility to induce AFP-specific T-lymphocytes in patients with HCC and/or cirrhosis...
  14. ncbi Establishment of an orthotopic tumour model for hepatocellular carcinoma and non-invasive in vivo tumour imaging by high resolution ultrasound in mice
    Volker Schmitz
    Department of Internal Medicine I, University Hospital Bonn, Bonn, Germany
    J Hepatol 40:787-91. 2004
    ..In this study we established an orthotopic tumour model for hepatocellular carcinoma and evaluated a non-invasive high resolution ultrasound technique for diagnosis and follow-up of intrahepatic HCC...
  15. pmc Invasive fungal infections in neutropenic enterocolitis: a systematic analysis of pathogens, incidence, treatment and mortality in adult patients
    Marcus Gorschlüter
    Department of Internal Medicine I, University of Bonn, Germany
    BMC Infect Dis 6:35. 2006
    ..Fungi have also been reported, but their practical relevance remains unclear. The guidelines do not address concrete treatment recommendations for fungal neutropenic enterocolitis...
  16. ncbi Combination of systemic thioacetamide (TAA) injections and ethanol feeding accelerates hepatic fibrosis in C3H/He mice and is associated with intrahepatic up regulation of MMP-2, VEGF and ICAM-1
    Miroslaw Kornek
    Department of Internal Medicine I, University Hospital Bonn, Germany
    J Hepatol 45:370-6. 2006
    ..Most experimental therapeutic studies are performed in mice without pre-damaged livers...
  17. pmc Plasminogen fragment K1-5 improves survival in a murine hepatocellular carcinoma model
    Volker Schmitz
    Department of Internal Medicine I, University Hospital Bonn, Sigmund Freud Strasse 25, 53105 Bonn, Germany
    Gut 56:271-8. 2007
    ..The prognosis of patients with hepatocellular carcinoma (HCC) remains poor, and new alternative treatments are needed...
  18. ncbi Dexamethasone, high-dose cytarabine, and cisplatin in combination with rituximab as salvage treatment for patients with relapsed or refractory aggressive non-Hodgkin's lymphoma
    Ulrich J M Mey
    Department of Internal Medicine I, University of Bonn, Germany
    Cancer Invest 24:593-600. 2006
    ..With a median follow-up of 24.9 months, median overall and progression-free survivals were 8.5 and 6.7 months, respectively. Immunochemotherapy with rituximab and DHAP proved to be feasible and effective in this patient population...
  19. ncbi DHAP in combination with rituximab vs DHAP alone as salvage treatment for patients with relapsed or refractory diffuse large B-cell lymphoma: a matched-pair analysis
    Ulrich J M Mey
    Department of Internal Medicine I, University of Bonn, Germany
    Leuk Lymphoma 47:2558-66. 2006
    ..However, differences with regard to complete remission rates failed to reach statistical significance, thereby necessitating further evaluation of the role of combined immunochemotherapy in this patient population...
  20. ncbi Diffuse alveolar haemorrhage in a systemic lupus erythematosus patient successfully treated with rituximab: a case report
    Cordula M Nellessen
    Universitatsklinikum Bonn, Medizinische Klinik und Poliklinik I Allgemeine Innere Medizin, Sigmund Freud Str 25, D 53127 Bonn, Germany
    Nephrol Dial Transplant 23:385-6. 2008
  21. doi Prevention of paracentesis-induced circulatory dysfunction: midodrine vs albumin. A randomized pilot study
    Beate Appenrodt
    Department of Internal Medicine I, University of Bonn, Bonn, Germany
    Liver Int 28:1019-25. 2008
    ..Vasoconstrictors, e.g. terlipressin, may also prevent PICD. The aim was to compare the less expensive vasoconstrictor midodrine, an alpha-adrenoceptor agonist, with albumin in preventing PICD...
  22. ncbi Pseudomembranous and obstructive Aspergillus tracheobronchitis - optimal diagnostic strategy and outcome
    Selcuk Tasci
    Department of Internal Medicine II, University of Bonn, Germany
    Mycoses 49:37-42. 2006
    ..Prognosis of PMATB and OATB remains poor. Microscopy of respiratory specimens is the most sensitive tool to confirm the diagnosis. The characteristic appearance of the disease makes it possible to start antifungal therapy immediately...
  23. doi Is detection of bacterial DNA in ascitic fluid of clinical relevance?
    Beate Appenrodt
    Departments of aInternal Medicine I, University of Bonn, Bonn, Germany
    Eur J Gastroenterol Hepatol 22:1487-94. 2010
    ..However, the clinical relevance of this finding is ill-defined especially compared with the standard diagnostics for detection of spontaneous bacterial peritonitis (SBP). Furthermore, other DNA tests have not been sufficiently evaluated...
  24. ncbi Treatment of metastatic colorectal carcinomas by systemic inhibition of vascular endothelial growth factor signaling in mice
    Volker Schmitz
    Medizinische Klinik I, Sigmund Freud Str 25, Bonn 53105, Germany
    World J Gastroenterol 11:4332-6. 2005
    ..Here, we tested a recombinant adenovirus, AdsFlt1-3, that encodes an antagonistically acting fragment of the VEGF receptor 1 (Flt-1), for systemic antitumor effects in pre-established subcutaneous CRC tumors in mice...
  25. ncbi Successful transplantation of a liver from a donor with fatal ethylene glycol poisoning
    Martin Wolff
    Department of Surgery, University of Bonn, Germany
    Liver Transpl 11:990-2. 2005
  26. ncbi Increased urotensin II plasma levels in patients with cirrhosis and portal hypertension
    Jorg Heller
    Department of Internal Medicine I, University of Bonn, Sigmund Freud Strasse 25, D 53105 Bonn, Germany
    J Hepatol 37:767-72. 2002
    ..We therefore investigated the role of Urotensin II (U II), a newly described peptide reported to be a vasoconstrictor in the central arterial compartment and a vasodilator in the splanchnic vasculature...
  27. ncbi Effective antitumour mono- and combination therapy by gene delivery of angiostatin-like molecule and interleukin-12 in a murine hepatoma model
    Volker Schmitz
    Department of Internal Medicine I, University Hospital Bonn, Bonn, Germany
    Int J Colorectal Dis 20:494-501. 2005
    ..We applied an experimental approach employing two recombinant adenoviral vectors (Ad) that express interleukin-12 (IL-12) and angiostatin-like molecule (K1-3) respectively to a subcutaneous hepatoma model in mice...
  28. ncbi [Long-term outcome of intrapleural fibrinolytic therapy via small-bore catheter drainage in the management of complicated parapneumonic effusion and empyema-a case series]
    Selcuk Tasci
    Medizinische Klinik und Poliklinik II, Universitatsklinikum, Bonn
    Med Klin (Munich) 100:181-5. 2005
    ..Intrapleural fibrinolytic therapy (IFT) has been established, besides video-assisted thoracoscopy (VATS), in the management of PPE and PE. Combination of IFT and small-bore catheter drainage has previously not been investigated...
  29. ncbi Prognostic impact of renal impairment and sodium imbalance in patients undergoing transjugular intrahepatic portosystemic shunting for the prevention of variceal rebleeding
    Michael Schepke
    Department of Internal Medicine I, University of Bonn, Bonn, Germany
    Digestion 67:146-53. 2003
    ....
  30. doi Chromocolonoscopy detects more adenomas than white light colonoscopy or narrow band imaging colonoscopy in hereditary nonpolyposis colorectal cancer screening
    R Hüneburg
    Department of Internal Medicine I, University of Bonn, Germany
    Endoscopy 41:316-22. 2009
    ..It was the aim of the present study to assess the detection rate of polypoid lesions by comparing chromocolonoscopy with standard white light colonoscopy and narrow-band imaging (NBI) colonoscopy...
  31. ncbi Altered expression of TGF-beta receptors in hepatocellular carcinoma--effects of a constitutively active TGF-beta type I receptor mutant
    Annemarie Musch
    Department of Medicine I, University of Bonn, Germany
    Digestion 71:78-91. 2005
    ..Hepatocellular carcinomas (HCC) often show resistance to the effects of transforming growth factor-beta (TGF-beta). This study focuses on molecular mechanisms of this resistance to explore ways to overcome it...
  32. ncbi Increased VEGF levels induced by anti-VEGF treatment are independent of tumor burden in colorectal carcinomas in mice
    V Schmitz
    Department of Internal Medicine I, University Hospital, Bonn, Germany
    Gene Ther 13:1198-205. 2006
    ....
  33. ncbi Goodpasture's syndrome with massive pulmonary haemorrhage in the absence of circulating anti-GBM antibodies?
    Matthias Alexander Hellmann
    Medizinische Klinik und Poliklinik I, Universitatsklinikum Bonn, Germany
    Nephrol Dial Transplant 21:526-9. 2006
  34. doi Recovery from ultra-high dose organophosphate poisoning after "in-the-field" antidote treatment: potential lessons for civil defense
    Jan Wilko Schrickel
    Department of Internal Medicine II, University of Bonn, Bonn, Germany
    J Emerg Med 37:279-82. 2009
    ..We believe that in cases of mass poisonings--for example, terrorist activity--therapy must be available on the scene as soon as possible. This also may require decentralized antidote storage...
  35. ncbi Requirements for adeno-associated virus-derived non-viral vectors to achieve stable and site-specific integration of plasmid DNA in liver carcinoma cells
    Robin Steigerwald
    Department of Virus Research, Max Plank Institute for Biochemistry, Martinsried, Germany
    Digestion 68:13-23. 2003
    ..We therefore studied the minimal elements of gene therapy vectors necessary for stable integration and tested the effectiveness of this approach in hepatoma cells...
  36. ncbi Accumulation of 8-hydroxy-2'-deoxyguanosine adducts in HBx recombinant HepG2 cells and HBx transgenic mice
    Ralph Gehrke
    Department of Virus Research, Max Planck Institut fur Biochemie, Martinsried, Germany
    Digestion 70:117-26. 2004
    ..Therefore, we investigated whether HBx expression increases the level of the mutational precursor 8-hydroxy-2'-deoxyguanosine in hepatocellular DNA...