M Punzel

Summary

Affiliation: University of Heidelberg
Country: Germany

Publications

  1. ncbi request reprint Divisional history and pluripotency of human hematopoietic stem cells
    M Punzel
    Medizinische Poliklinik, University of Heidelberg, Hospital Str 3, 69115 Heidelberg, Germany
    Ann N Y Acad Sci 938:72-81; discussion 81-2. 2001
  2. ncbi request reprint The microenvironment of AFT024 cells maintains primitive human hematopoiesis by counteracting contact mediated inhibition of proliferation
    Michael Punzel
    Department of Medicine, Division of Hematology and Stem Cell Institute, University of Minnesota, Minneapolis, MN, USA
    Cell Commun Adhes 9:149-59. 2002
  3. ncbi request reprint Single adult human CD34(+)/Lin-/CD38(-) progenitors give rise to natural killer cells, B-lineage cells, dendritic cells, and myeloid cells
    J S Miller
    Department of Medicine, University of Minnesota Cancer Center, Minneapolis, MN 55455, USA
    Blood 93:96-106. 1999
  4. ncbi request reprint Functional analysis of initial cell divisions defines the subsequent fate of individual human CD34(+)CD38(-) cells
    Michael Punzel
    Department of Medicine V, University of Heidelberg, Heidelberg, Germany
    Exp Hematol 30:464-72. 2002
  5. ncbi request reprint The symmetry of initial divisions of human hematopoietic progenitors is altered only by the cellular microenvironment
    Michael Punzel
    Department of Medicine V, University of Heidelberg, Heidelberg, Germany
    Exp Hematol 31:339-47. 2003
  6. ncbi request reprint Hematopoietic stem cells: can old cells learn new tricks?
    Anthony D Ho
    Department of Medicine V, University of Heidelberg, Germany
    J Leukoc Biol 73:547-55. 2003
  7. doi request reprint Lineage development of hematopoietic stem and progenitor cells
    Bernd Giebel
    Institute for Transplantation Diagnostics and Cellular Therapeutics, Heinrich Heine University, Dusseldorf, Germany
    Biol Chem 389:813-24. 2008
  8. ncbi request reprint Nucleofection, an efficient nonviral method to transfer genes into human hematopoietic stem and progenitor cells
    Gregor von Levetzow
    Institute for Transplantation Diagnostics and Cell Therapeutics, Heinrich Heine University Dusseldorf, D 40225 Dusseldorf, Germany
    Stem Cells Dev 15:278-85. 2006
  9. ncbi request reprint The neurotransmitter GABA is a potent inhibitor of the stromal cell-derived factor-1alpha induced migration of adult CD133+ hematopoietic stem and progenitor cells
    Jeanette Seidel
    Institute of Immunology, Witten Herdecke University, 58448 Witten, Germany
    Stem Cells Dev 16:827-36. 2007
  10. ncbi request reprint Relevance of C1 and C2 epitopes for hemopoietic stem cell transplantation: role for sequential acquisition of HLA-C-specific inhibitory killer Ig-like receptor
    Johannes C Fischer
    Institute for Transplantation Diagnostics and Cell Therapeutics, Heinrich Heine University Dusseldorf, Moorenstrasse 5, D 40225 Dusseldorf, Germany
    J Immunol 178:3918-23. 2007

Collaborators

Detail Information

Publications12

  1. ncbi request reprint Divisional history and pluripotency of human hematopoietic stem cells
    M Punzel
    Medizinische Poliklinik, University of Heidelberg, Hospital Str 3, 69115 Heidelberg, Germany
    Ann N Y Acad Sci 938:72-81; discussion 81-2. 2001
    ..In addition, the much more primitive Myeloid-Lymphoid Initiating Cells (ML-IC) are predominantly found in the PKH-bright population. Thus, primitive function of individual candidate HSCs closely related to their divisional behavior...
  2. ncbi request reprint The microenvironment of AFT024 cells maintains primitive human hematopoiesis by counteracting contact mediated inhibition of proliferation
    Michael Punzel
    Department of Medicine, Division of Hematology and Stem Cell Institute, University of Minnesota, Minneapolis, MN, USA
    Cell Commun Adhes 9:149-59. 2002
    ..In conclusion, AFT024 cells produce factor(s), that counteract contact induced growth inhibition of primitive human hematopoietic progenitors, leading to expansion of these cells in contact with the microenvironment...
  3. ncbi request reprint Single adult human CD34(+)/Lin-/CD38(-) progenitors give rise to natural killer cells, B-lineage cells, dendritic cells, and myeloid cells
    J S Miller
    Department of Medicine, University of Minnesota Cancer Center, Minneapolis, MN 55455, USA
    Blood 93:96-106. 1999
    ..This study provides new insights into the role of the microenvironment niche, which governs the earliest events in lymphoid development...
  4. ncbi request reprint Functional analysis of initial cell divisions defines the subsequent fate of individual human CD34(+)CD38(-) cells
    Michael Punzel
    Department of Medicine V, University of Heidelberg, Heidelberg, Germany
    Exp Hematol 30:464-72. 2002
    ..We assessed the relationship of individual cell divisional behavior with the functional fate of stem cell candidates at the single cell level...
  5. ncbi request reprint The symmetry of initial divisions of human hematopoietic progenitors is altered only by the cellular microenvironment
    Michael Punzel
    Department of Medicine V, University of Heidelberg, Heidelberg, Germany
    Exp Hematol 31:339-47. 2003
    ..We examined if cellular elements or adhesive ligands were able to alter asymmetric divisions of CD34(+)/CD38(-) cells in contrast to soluble factors at a single cell level...
  6. ncbi request reprint Hematopoietic stem cells: can old cells learn new tricks?
    Anthony D Ho
    Department of Medicine V, University of Heidelberg, Germany
    J Leukoc Biol 73:547-55. 2003
    ....
  7. doi request reprint Lineage development of hematopoietic stem and progenitor cells
    Bernd Giebel
    Institute for Transplantation Diagnostics and Cellular Therapeutics, Heinrich Heine University, Dusseldorf, Germany
    Biol Chem 389:813-24. 2008
    ..Together with some phenotypic criteria that characterize different subsets of multipotent and lineage-restricted progenitor cells, we summarize these recent findings here...
  8. ncbi request reprint Nucleofection, an efficient nonviral method to transfer genes into human hematopoietic stem and progenitor cells
    Gregor von Levetzow
    Institute for Transplantation Diagnostics and Cell Therapeutics, Heinrich Heine University Dusseldorf, D 40225 Dusseldorf, Germany
    Stem Cells Dev 15:278-85. 2006
    ..Therefore, we conclude, the nucleofection method is a reliable and efficient method to manipulate primitive hematopoietic cells genetically...
  9. ncbi request reprint The neurotransmitter GABA is a potent inhibitor of the stromal cell-derived factor-1alpha induced migration of adult CD133+ hematopoietic stem and progenitor cells
    Jeanette Seidel
    Institute of Immunology, Witten Herdecke University, 58448 Witten, Germany
    Stem Cells Dev 16:827-36. 2007
    ..In summary, the neurotransmitter GABA is a potent blocker of the SDF-1alpha-induced migration of CD133(+) HSPCs from mobilized peripheral blood...
  10. ncbi request reprint Relevance of C1 and C2 epitopes for hemopoietic stem cell transplantation: role for sequential acquisition of HLA-C-specific inhibitory killer Ig-like receptor
    Johannes C Fischer
    Institute for Transplantation Diagnostics and Cell Therapeutics, Heinrich Heine University Dusseldorf, Moorenstrasse 5, D 40225 Dusseldorf, Germany
    J Immunol 178:3918-23. 2007
    ..These findings define a novel determinant for understanding the role of NK cells in clinical hemopoietic stem cell transplantation...
  11. ncbi request reprint Primitive human hematopoietic cells give rise to differentially specified daughter cells upon their initial cell division
    Bernd Giebel
    Institute for Transplantation Diagnostics and Cell Therapeutics, Heinrich Heine University Dusseldorf, D 40225 Dusseldorf, Germany
    Blood 107:2146-52. 2006
    ..In addition, we describe a novel human hematopoietic progenitor cell that has the capacity to form natural killer (NK) cells as well as macrophages, but not cells of other myeloid lineages...
  12. doi request reprint Cytokine combinations differentially influence the SDF-1alpha-dependent migratory activity of cultivated murine hematopoietic stem and progenitor cells
    Susannah H Kassmer
    Institute of Immunology, Witten Herdecke University, Stockumer Strasse 10, Witten, Germany
    Biol Chem 389:863-72. 2008
    ..This indicates that hematopoietic cytokines can have a significant impact on SDF-1alpha-stimulated migratory activity and the underlying intracellular signaling processes in cultivated HSPCs...