Jan Postberg

Summary

Affiliation: University of Witten/Herdecke
Country: Germany

Publications

  1. ncbi request reprint Synthesis of pre-rRNA and mRNA is directed to a chromatin-poor compartment in the macronucleus of the spirotrichous ciliate Stylonychia lemnae
    Jan Postberg
    Institute of Cell Biology, University of Witten Herdecke, Stockumer Str 10, 58453, Witten, Germany
    Chromosome Res 14:161-75. 2006
  2. ncbi request reprint Exploiting nuclear duality of ciliates to analyse topological requirements for DNA replication and transcription
    Jan Postberg
    Institute of Cell Biology, University of Witten Herdecke, Stockumer Str 10, 58453 Witten, Germany
    J Cell Sci 118:3973-83. 2005
  3. doi request reprint Handling S/MAR vectors
    Claudia Hagedorn
    Centre for Biomedical Education and Research, Institute of Cell Biology, University of Witten Herdecke, 58453 Witten, Germany
    Cold Spring Harb Protoc 2012:657-63. 2012
  4. ncbi request reprint Telomere end-binding proteins control the formation of G-quadruplex DNA structures in vivo
    Katrin Paeschke
    Institute of Cell Biology, University Witten Herdecke, Stockumer Strasse 10, 58453 Witten, Germany
    Nat Struct Mol Biol 12:847-54. 2005
  5. doi request reprint Rescue of S/MAR-containing nonviral episomal expression vectors
    Claudia Hagedorn
    Centre for Biomedical Education and Research, Institute of Cell Biology, University of Witten Herdecke, 58453 Witten, Germany
    Cold Spring Harb Protoc 2012:709-11. 2012
  6. ncbi request reprint The telomerase-associated protein p43 is involved in anchoring telomerase in the nucleus
    Matthias Möllenbeck
    Institute of Cell Biology, University Witten Herdecke, Stockumer Strasse 10, D 58453 Witten, Germany
    J Cell Sci 116:1757-61. 2003
  7. pmc A telomerase-associated RecQ protein-like helicase resolves telomeric G-quadruplex structures during replication
    Jan Postberg
    Centre for Biomedical Education and Research, Institute of Cell Biology, Witten, Germany
    Gene 497:147-54. 2012
  8. pmc Establishment and mitotic stability of an extra-chromosomal mammalian replicon
    Isa M Stehle
    Institute of Cell Biology, University Witten Herdecke, Witten, Germany
    BMC Cell Biol 8:33. 2007
  9. doi request reprint Evolutionary origin of the cell nucleus and its functional architecture
    Jan Postberg
    University of Witten Herdecke, Center for Biomedical Education and Research ZBAF, Institute of Cell Biology, Witten, Germany
    Essays Biochem 48:1-24. 2010
  10. pmc The evolutionary history of histone H3 suggests a deep eukaryotic root of chromatin modifying mechanisms
    Jan Postberg
    Institute of Cell Biology, University of Witten Herdecke, Witten, Germany
    BMC Evol Biol 10:259. 2010

Collaborators

Detail Information

Publications16

  1. ncbi request reprint Synthesis of pre-rRNA and mRNA is directed to a chromatin-poor compartment in the macronucleus of the spirotrichous ciliate Stylonychia lemnae
    Jan Postberg
    Institute of Cell Biology, University of Witten Herdecke, Stockumer Str 10, 58453, Witten, Germany
    Chromosome Res 14:161-75. 2006
    ..We assume that vectorial synthesis and processing of rRNA and mRNA is directed to a functional interchromatin compartment...
  2. ncbi request reprint Exploiting nuclear duality of ciliates to analyse topological requirements for DNA replication and transcription
    Jan Postberg
    Institute of Cell Biology, University of Witten Herdecke, Stockumer Str 10, 58453 Witten, Germany
    J Cell Sci 118:3973-83. 2005
    ..Moreover nuclear duality inherent to ciliates with their germline micronucleus and their somatic macronucleus may eventually provide further insight into epigenetic regulation of transcription, replication and nuclear differentiation...
  3. doi request reprint Handling S/MAR vectors
    Claudia Hagedorn
    Centre for Biomedical Education and Research, Institute of Cell Biology, University of Witten Herdecke, 58453 Witten, Germany
    Cold Spring Harb Protoc 2012:657-63. 2012
    ..Furthermore, S/MAR vector systems are not trivial to handle and several critical technical issues have to be considered when modifying these vectors for various applications...
  4. ncbi request reprint Telomere end-binding proteins control the formation of G-quadruplex DNA structures in vivo
    Katrin Paeschke
    Institute of Cell Biology, University Witten Herdecke, Stockumer Strasse 10, 58453 Witten, Germany
    Nat Struct Mol Biol 12:847-54. 2005
    ..We have also found that G-quadruplex formation in vivo is regulated by the cell cycle-dependent phosphorylation of TEBPbeta...
  5. doi request reprint Rescue of S/MAR-containing nonviral episomal expression vectors
    Claudia Hagedorn
    Centre for Biomedical Education and Research, Institute of Cell Biology, University of Witten Herdecke, 58453 Witten, Germany
    Cold Spring Harb Protoc 2012:709-11. 2012
    ..Bacteria are transformed with this DNA and if episomal plasmid DNA (pDNA) is present, resistant bacterial colonies will form...
  6. ncbi request reprint The telomerase-associated protein p43 is involved in anchoring telomerase in the nucleus
    Matthias Möllenbeck
    Institute of Cell Biology, University Witten Herdecke, Stockumer Strasse 10, D 58453 Witten, Germany
    J Cell Sci 116:1757-61. 2003
    ....
  7. pmc A telomerase-associated RecQ protein-like helicase resolves telomeric G-quadruplex structures during replication
    Jan Postberg
    Centre for Biomedical Education and Research, Institute of Cell Biology, Witten, Germany
    Gene 497:147-54. 2012
    ..This finding can be incorporated into a mechanistic model about the replication of telomeric G-quadruplex structures during the cell cycle...
  8. pmc Establishment and mitotic stability of an extra-chromosomal mammalian replicon
    Isa M Stehle
    Institute of Cell Biology, University Witten Herdecke, Witten, Germany
    BMC Cell Biol 8:33. 2007
    ..In order to uncouple local and long-range epigenetic features we used an extra-chromosomal replicon to study the requirements for replication and segregation and compared its behavior to that of its integrated counterpart...
  9. doi request reprint Evolutionary origin of the cell nucleus and its functional architecture
    Jan Postberg
    University of Witten Herdecke, Center for Biomedical Education and Research ZBAF, Institute of Cell Biology, Witten, Germany
    Essays Biochem 48:1-24. 2010
    ..We conclude this chapter with a reflection on the necessity of interdisciplinary research strategies to map epigenomes in space and time...
  10. pmc The evolutionary history of histone H3 suggests a deep eukaryotic root of chromatin modifying mechanisms
    Jan Postberg
    Institute of Cell Biology, University of Witten Herdecke, Witten, Germany
    BMC Evol Biol 10:259. 2010
    ..Even less understood is the conservation of epigenetic mechanisms among eukaryotes and their origins...
  11. doi request reprint The unusual way to make a genetically active nucleus
    Franziska Jönsson
    Institute of Cell Biology, University Witten Herdecke, Witten, Germany
    DNA Cell Biol 28:71-8. 2009
    ....
  12. pmc snRNA and heterochromatin formation are involved in DNA excision during macronuclear development in stichotrichous ciliates
    Stefan A Juranek
    Institute of Cell Biology, University Witten Herdecke, Stockumer Str 10, D 58453 Witten, Germany
    Eukaryot Cell 4:1934-41. 2005
    ....
  13. doi request reprint A colony-forming assay for determining the establishment efficiency of S/MAR-containing nonviral episomal expression vectors
    Claudia Hagedorn
    Centre for Biomedical Education and Research, Institute of Cell Biology, University of Witten Herdecke, 58453 Witten, Germany
    Cold Spring Harb Protoc 2012:706-8. 2012
    ..Expected establishment efficiency for S/MAR vectors is 1-5%. This article describes a colony-forming assay that may be used either to determine establishment efficiency or to generate single cell clones...
  14. pmc A permissive chromatin structure is adopted prior to site-specific DNA demethylation of developmentally expressed genes involved in macronuclear differentiation
    Aneta Bulic
    Institute of Cell Biology, Centre for Biomedical Education and Research, Witten Herdecke University, Witten, Germany
    Epigenetics Chromatin 6:5. 2013
    ..In the macronucleus of these cells, the DNA is fragmented into individual short DNA molecules, each representing a functional expression and replication unit. Therefore, long range epigenomic interaction can be excluded in this system...
  15. ncbi request reprint Organization of the macronuclear gene-sized pieces of stichotrichous ciliates into a higher order structure via telomere-matrix interactions
    Franziska Jönsson
    Institute of Cell Biology, University Witten Herdecke, Stockumer Str 10, D 58448 Witten, Germany
    Chromosome Res 10:445-53. 2002
    ..These data not only allow us to propose a model for macronuclear architecture but may also be relevant for further analysis of telomere-matrix interactions in higher eukaryotes...
  16. ncbi request reprint The Euplotes La motif protein p43 has properties of a telomerase-specific subunit
    Stefan Aigner
    Department of Chemistry and Biochemistry and Howard Hughes Medical Institute, University of Colorado, Boulder, Colorado 80309 0215, USA
    Biochemistry 42:5736-47. 2003
    ..Thus, p43 joins the telomerase reverse transcriptase and the yeast proteins Est1p and Est3p as the only telomerase-specific proteins identified so far...