Research Topics
| Alexandra PhilipsenSummaryAffiliation: University Hospital Country: Germany Publications
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Detail Information
Publications
Borderline typical symptoms in adult patients with attention deficit/hyperactivity disorderAlexandra Philipsen
Department of Psychiatry and Psychotherapy, University of Freiburg Medical School, Germany
Atten Defic Hyperact Disord 1:11-8. 2009..Females with ADHD and BPD share more clinical features than males. However, symptoms of self-destruction and affect dysregulation appear to be more severe in BPD patients...
Subtype differences in adults with attention-deficit/hyperactivity disorder (ADHD) with regard to ADHD-symptoms, psychiatric comorbidity and psychosocial adjustmentEsther Sobanski
Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, J 5, 68159 Mannheim, Germany
Eur Psychiatry 23:142-9. 2008..To date, nearly all research of subtype differences in ADHD has been performed in children and only two studies, with conflicting results, have covered this subject in adults with ADHD...- Psychotherapy in adult attention deficit hyperactivity disorder: implications for treatment and researchAlexandra Philipsen
Department of Psychiatry and Psychotherapy, University Medical Centre Freiburg, Hauptstrasse 5, D 79104 Freiburg, Germany
Expert Rev Neurother 12:1217-25. 2012..Finally, the specific requirements of psychotherapy for adult ADHD as well as further research questions will be discussed... - Evaluation of the efficacy and effectiveness of a structured disorder tailored psychotherapy in ADHD in adults: study protocol of a randomized controlled multicentre trialAlexandra Philipsen
Department of Psychiatry and Psychotherapy, University Medical Center Freiburg, Germany
Atten Defic Hyperact Disord 2:203-12. 2010..The trial is funded by the German Federal Ministry of Research and Education (01GV0606) and is part of the German network for the treatment of ADHD in children and adults (ADHD-NET)... - Sleep and sleep disorders in adults with attention deficit/hyperactivity disorderAlexandra Philipsen
Department of Psychiatry and Psychotherapy, University of Freiburg Medical School, Haupt strasse 5, 79104 Freiburg, Germany
Sleep Med Rev 10:399-405. 2006..To date, larger studies with adequate sample sizes that compare sleep in adult patients with ADHD, healthy control groups and patients with other primary sleep disorders are still lacking... - Structured group psychotherapy in adults with attention deficit hyperactivity disorder: results of an open multicentre studyAlexandra Philipsen
Department of Psychiatry and Psychotherapy, University of Freiburg Medical School, Freiburg, Germany
J Nerv Ment Dis 195:1013-9. 2007..In this multicenter study, the therapy program showed therapist-independent effects and seemed to be disorder-specific. This warrants the effort of organizing further controlled studies... - Sleep in adults with attention-deficit/hyperactivity disorder: a controlled polysomnographic study including spectral analysis of the sleep EEGAlexandra Philipsen
Department of Psychiatry and Psychotherapy, University of Freiburg Medical School, Germany
Sleep 28:877-84. 2005..We investigated objective and subjective sleep quality in adultADHD, including an electroencephalogram spectral power analysis... - Attention-deficit hyperactivity disorder as a potentially aggravating factor in borderline personality disorderAlexandra Philipsen
Department of Psychiatry and Psychotherapy, University Medical Center, Freiburg, Germany
Br J Psychiatry 192:118-23. 2008..Clinical experience suggests that people with borderline personality disorder often meet criteria for attention-deficit hyperactivity disorder (ADHD). However, empirical data are sparse... - Increased delta power and discrepancies in objective and subjective sleep measurements in borderline personality disorderAlexandra Philipsen
Department of Psychiatry and Psychotherapy, University of Freiburg Medical School, Haupt strasse 5, 79104 Freiburg, Germany
J Psychiatr Res 39:489-98. 2005..Earlier findings in sleep EEG abnormalities in BPD may have been confounded by concomitant depressive symptoms... - Small amygdala-high aggression? The role of the amygdala in modulating aggression in healthy subjectsSwantje Matthies
Department of Psychiatry and Psychotherapy, University Medical Centre Freiburg, Freiburg, Germany
World J Biol Psychiatry 13:75-81. 2012..In order to better understand the physiological role of the amygdala in modulating aggressive behaviour we investigated the relationship between amygdala volumes and lifetime aggression in healthy subjects... - Elevated pain thresholds correlate with dissociation and aversive arousal in patients with borderline personality disorderPetra Ludäscher
Department of Psychiatry and Psychotherapy, University of Freiburg Medical School, Germany
Psychiatry Res 149:291-6. 2007..Measuring electric pain thresholds is a valid and reasonable method for larger studies... - Clonidine in acute aversive inner tension and self-injurious behavior in female patients with borderline personality disorderAlexandra Philipsen
Department of Psychiatry and Psychotherapy, University of Freiburg Medical School, Freiburg, Germany
J Clin Psychiatry 65:1414-9. 2004..Further placebo-controlled studies with larger populations are needed to confirm this finding... 
Polysomnography findings in patients with restless legs syndrome and in healthy controls: a comparative observational studyMagdolna Hornyak
Center for Sleep Research and Sleep Medicine, Department of Psychiatry and Psychotherapy, University Medical Center Freiburg, Germany
Sleep 30:861-5. 2007..Sleep disturbances and their sequelae are the most common complaints of patients with restless legs syndrome (RLS). We compared polysomnography (PSG) findings in a large cohort of patients with idiopathic RLS and of healthy subjects...- Severity of childhood attention-deficit hyperactivity disorder--a risk factor for personality disorders in adult life?Swantje Matthies
Department of Psychiatry and Psychotherapy, University Medical Centre Freiburg, Hauptstr 5 D 79104, Freiburg, Germany
J Pers Disord 25:101-14. 2011..Applying the IPDE we confirmed a high number of PDs among adult ADHD patients. Our findings point to a higher vulnerability for the development of PDs in patients with severe childhood ADHD... - Hippocampus and amygdala morphology in adults with attention-deficit hyperactivity disorderEvgeniy Perlov
Department of Psychiatry and Psychotherapy, University Hospital Freiburg, Freiburg, Germany
J Psychiatry Neurosci 33:509-15. 2008..We sought to test the hypothesis that, like in pediatric patients, there might be hippocampus and amygdala volume abnormalities in adult patients with ADHD... - Spectroscopic findings in attention-deficit/hyperactivity disorder: review and meta-analysisEvgeniy Perlov
Department of Psychiatry and Psychotherapy, University Hospital Freiburg, Freiburg, Germany
World J Biol Psychiatry 10:355-65. 2009..In this paper we review published MRS results with respect to childhood, adolescence and adult ADHD... - Clarifying the role of the rostral dmPFC/dACC in fear/anxiety: learning, appraisal or expression?Simon Maier
Department of Psychiatry and Psychotherapy, University Medical Center Freiburg, Freiburg im Breisgau, Germany
PLoS ONE 7:e50120. 2012..We discuss the broader implications of this finding for our understanding of mPFC/ACC function in fear and in negative emotion more generally... - Neural correlates of interference inhibition, action withholding and action cancelation in adult ADHDAlexandra Sebastian
Department of Psychiatry and Psychotherapy, Albert Ludwigs University Freiburg, Germany
Psychiatry Res 202:132-41. 2012.... - Visual cortex abnormalities in adults with ADHD: a structural MRI studyJohannes Ahrendts
Section for Experimental NeuroPsychiatry, Department of Psychiatry and Psychotherapy, University of Freiburg Medical Center, Freiburg, Germany
World J Biol Psychiatry 12:260-70. 2011..The aim of this study was to clarify the involvement of prefronto-striatal and posterior parietal areas in adult ADHD... - Orbitofrontal reward sensitivity and impulsivity in adult attention deficit hyperactivity disorderGregor Wilbertz
Department of Psychiatry and Psychotherapy, University Hospital Freiburg, Germany
Neuroimage 60:353-61. 2012..Reward value processing difficulties in ADHD should be considered when assessing reward anticipation and emotional learning in research and applied settings... - Differential diagnosis and comorbidity of attention-deficit/hyperactivity disorder (ADHD) and borderline personality disorder (BPD) in adultsAlexandra Philipsen
Department of Psychiatry and Psychotherapy, University of Freiburg Medical School, Hauptstr 5, 79104, Freiburg, Germany
Eur Arch Psychiatry Clin Neurosci 256:i42-6. 2006.... - Increased diurnal salivary cortisol in women with borderline personality disorderKlaus Lieb
Department of Psychiatry and Psychotherapy, University of Freiburg Medical School, Hauptstr 5, D 79104 Freiburg, Germany
J Psychiatr Res 38:559-65. 2004..Increased adrenal activity and lowered feedback sensitivity of the HPA-axis may characterise BPD. Further studies have to reveal reasons of heightened adrenal activity in these patients... - Corpus callosum dysplasia in adult attention-deficit/ hyperactivity disorder: a case reportAlexandra Philipsen
J Clin Psychiatry 68:1985-8. 2007 - Psychiatric comorbidity and functional impairment in a clinically referred sample of adults with attention-deficit/hyperactivity disorder (ADHD)Esther Sobanski
Department of Psychiatry and Psychotherapy Central Institute of Mental Health, J 5, 68159 Mannheim, Germany
Eur Arch Psychiatry Clin Neurosci 257:371-7. 2007.... - No association between a common haplotype of the 6 and 10-repeat alleles in intron 8 and the 3'UTR of the DAT1 gene and adult attention deficit hyperactivity disorderDaniel Brüggemann
Department of Genetic Epidemology, Central Institute of Mental Health, Mannheim, Germany
Psychiatr Genet 17:121. 2007 - Differential nociceptive deficits in patients with borderline personality disorder and self-injurious behavior: laser-evoked potentials, spatial discrimination of noxious stimuli, and pain ratingsChristian Schmahl
Institute of Physiology and Pathophysiology, Johannes Gutenberg University, Mannheim, Germany
Pain 110:470-9. 2004..These findings suggest that hypoalgesia in BPD may primarily be due to altered intracortical processing similar to certain meditative states...