Alexandra Philipsen

Summary

Affiliation: University Hospital
Country: Germany

Publications

  1. doi request reprint Borderline typical symptoms in adult patients with attention deficit/hyperactivity disorder
    Alexandra Philipsen
    Department of Psychiatry and Psychotherapy, University of Freiburg Medical School, Germany
    Atten Defic Hyperact Disord 1:11-8. 2009
  2. ncbi request reprint Subtype differences in adults with attention-deficit/hyperactivity disorder (ADHD) with regard to ADHD-symptoms, psychiatric comorbidity and psychosocial adjustment
    Esther Sobanski
    Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, J 5, 68159 Mannheim, Germany
    Eur Psychiatry 23:142-9. 2008
  3. doi request reprint A randomized controlled multicenter trial on the multimodal treatment of adult attention-deficit hyperactivity disorder: enrollment and characteristics of the study sample
    Alexandra Philipsen
    Department of Psychiatry and Psychotherapy, University Medical Center Freiburg, Hauptstrasse 5, 79104, Freiburg, Germany
    Atten Defic Hyperact Disord 6:35-47. 2014
  4. pmc Predictors and impact of non-adherence in adults with attention-deficit/hyperactivity disorder receiving OROS methylphenidate: results from a randomized, placebo-controlled trial
    J J Sandra Kooij
    Psycho Medical Programs, PsyQ, Program Adult ADHD, Carel Reinierszkade 197, HR Den Haag 2593, The Netherlands
    BMC Psychiatry 13:36. 2013
  5. doi request reprint Psychotherapy in adult attention deficit hyperactivity disorder: implications for treatment and research
    Alexandra Philipsen
    Department of Psychiatry and Psychotherapy, University Medical Centre Freiburg, Hauptstrasse 5, D 79104 Freiburg, Germany
    Expert Rev Neurother 12:1217-25. 2012
  6. doi request reprint Evaluation of the efficacy and effectiveness of a structured disorder tailored psychotherapy in ADHD in adults: study protocol of a randomized controlled multicentre trial
    Alexandra Philipsen
    Department of Psychiatry and Psychotherapy, University Medical Center Freiburg, Germany
    Atten Defic Hyperact Disord 2:203-12. 2010
  7. ncbi request reprint Structured group psychotherapy in adults with attention deficit hyperactivity disorder: results of an open multicentre study
    Alexandra Philipsen
    Department of Psychiatry and Psychotherapy, University of Freiburg Medical School, Freiburg, Germany
    J Nerv Ment Dis 195:1013-9. 2007
  8. ncbi request reprint Sleep and sleep disorders in adults with attention deficit/hyperactivity disorder
    Alexandra Philipsen
    Department of Psychiatry and Psychotherapy, University of Freiburg Medical School, Haupt strasse 5, 79104 Freiburg, Germany
    Sleep Med Rev 10:399-405. 2006
  9. pmc Emotional modulation of motor response inhibition in women with borderline personality disorder: an fMRI study
    Gitta A Jacob
    Department of Psychiatry and Psychotherapy, University Medical Center Freiburg, Germany
    J Psychiatry Neurosci 38:164-72. 2013
  10. ncbi request reprint Sleep in adults with attention-deficit/hyperactivity disorder: a controlled polysomnographic study including spectral analysis of the sleep EEG
    Alexandra Philipsen
    Department of Psychiatry and Psychotherapy, University of Freiburg Medical School, Germany
    Sleep 28:877-84. 2005

Collaborators

Detail Information

Publications32

  1. doi request reprint Borderline typical symptoms in adult patients with attention deficit/hyperactivity disorder
    Alexandra Philipsen
    Department of Psychiatry and Psychotherapy, University of Freiburg Medical School, Germany
    Atten Defic Hyperact Disord 1:11-8. 2009
    ..Females with ADHD and BPD share more clinical features than males. However, symptoms of self-destruction and affect dysregulation appear to be more severe in BPD patients...
  2. ncbi request reprint Subtype differences in adults with attention-deficit/hyperactivity disorder (ADHD) with regard to ADHD-symptoms, psychiatric comorbidity and psychosocial adjustment
    Esther Sobanski
    Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, J 5, 68159 Mannheim, Germany
    Eur Psychiatry 23:142-9. 2008
    ..To date, nearly all research of subtype differences in ADHD has been performed in children and only two studies, with conflicting results, have covered this subject in adults with ADHD...
  3. doi request reprint A randomized controlled multicenter trial on the multimodal treatment of adult attention-deficit hyperactivity disorder: enrollment and characteristics of the study sample
    Alexandra Philipsen
    Department of Psychiatry and Psychotherapy, University Medical Center Freiburg, Hauptstrasse 5, 79104, Freiburg, Germany
    Atten Defic Hyperact Disord 6:35-47. 2014
    ....
  4. pmc Predictors and impact of non-adherence in adults with attention-deficit/hyperactivity disorder receiving OROS methylphenidate: results from a randomized, placebo-controlled trial
    J J Sandra Kooij
    Psycho Medical Programs, PsyQ, Program Adult ADHD, Carel Reinierszkade 197, HR Den Haag 2593, The Netherlands
    BMC Psychiatry 13:36. 2013
    ..The aim of this analysis was to determine predictors of non-adherence and impact of non-adherence on treatment response in adults with attention-deficit/hyperactivity disorder (ADHD)...
  5. doi request reprint Psychotherapy in adult attention deficit hyperactivity disorder: implications for treatment and research
    Alexandra Philipsen
    Department of Psychiatry and Psychotherapy, University Medical Centre Freiburg, Hauptstrasse 5, D 79104 Freiburg, Germany
    Expert Rev Neurother 12:1217-25. 2012
    ..Finally, the specific requirements of psychotherapy for adult ADHD as well as further research questions will be discussed...
  6. doi request reprint Evaluation of the efficacy and effectiveness of a structured disorder tailored psychotherapy in ADHD in adults: study protocol of a randomized controlled multicentre trial
    Alexandra Philipsen
    Department of Psychiatry and Psychotherapy, University Medical Center Freiburg, Germany
    Atten Defic Hyperact Disord 2:203-12. 2010
    ..The trial is funded by the German Federal Ministry of Research and Education (01GV0606) and is part of the German network for the treatment of ADHD in children and adults (ADHD-NET)...
  7. ncbi request reprint Structured group psychotherapy in adults with attention deficit hyperactivity disorder: results of an open multicentre study
    Alexandra Philipsen
    Department of Psychiatry and Psychotherapy, University of Freiburg Medical School, Freiburg, Germany
    J Nerv Ment Dis 195:1013-9. 2007
    ..In this multicenter study, the therapy program showed therapist-independent effects and seemed to be disorder-specific. This warrants the effort of organizing further controlled studies...
  8. ncbi request reprint Sleep and sleep disorders in adults with attention deficit/hyperactivity disorder
    Alexandra Philipsen
    Department of Psychiatry and Psychotherapy, University of Freiburg Medical School, Haupt strasse 5, 79104 Freiburg, Germany
    Sleep Med Rev 10:399-405. 2006
    ..To date, larger studies with adequate sample sizes that compare sleep in adult patients with ADHD, healthy control groups and patients with other primary sleep disorders are still lacking...
  9. pmc Emotional modulation of motor response inhibition in women with borderline personality disorder: an fMRI study
    Gitta A Jacob
    Department of Psychiatry and Psychotherapy, University Medical Center Freiburg, Germany
    J Psychiatry Neurosci 38:164-72. 2013
    ..Although both problems may be combined specifically in BPD, few studies to date have investigated the emotional modulation of impulsivity in BPD...
  10. ncbi request reprint Sleep in adults with attention-deficit/hyperactivity disorder: a controlled polysomnographic study including spectral analysis of the sleep EEG
    Alexandra Philipsen
    Department of Psychiatry and Psychotherapy, University of Freiburg Medical School, Germany
    Sleep 28:877-84. 2005
    ..We investigated objective and subjective sleep quality in adultADHD, including an electroencephalogram spectral power analysis...
  11. doi request reprint ADHD as a serious risk factor for early smoking and nicotine dependence in adulthood
    Swantje Matthies
    Department of Psychiatry and Psychotherapy, University Medical Centre Freiburg, Germany
    J Atten Disord 17:176-86. 2013
    ..To assess smoking habits in adults with ADHD, the authors used the Fagerström test for nicotine dependence (FTND)...
  12. doi request reprint Attention-deficit hyperactivity disorder as a potentially aggravating factor in borderline personality disorder
    Alexandra Philipsen
    Department of Psychiatry and Psychotherapy, University Medical Center, Freiburg, Germany
    Br J Psychiatry 192:118-23. 2008
    ..Clinical experience suggests that people with borderline personality disorder often meet criteria for attention-deficit hyperactivity disorder (ADHD). However, empirical data are sparse...
  13. ncbi request reprint Increased delta power and discrepancies in objective and subjective sleep measurements in borderline personality disorder
    Alexandra Philipsen
    Department of Psychiatry and Psychotherapy, University of Freiburg Medical School, Haupt strasse 5, 79104 Freiburg, Germany
    J Psychiatr Res 39:489-98. 2005
    ..Earlier findings in sleep EEG abnormalities in BPD may have been confounded by concomitant depressive symptoms...
  14. doi request reprint Small amygdala-high aggression? The role of the amygdala in modulating aggression in healthy subjects
    Swantje Matthies
    Department of Psychiatry and Psychotherapy, University Medical Centre Freiburg, Freiburg, Germany
    World J Biol Psychiatry 13:75-81. 2012
    ..In order to better understand the physiological role of the amygdala in modulating aggressive behaviour we investigated the relationship between amygdala volumes and lifetime aggression in healthy subjects...
  15. ncbi request reprint Clonidine in acute aversive inner tension and self-injurious behavior in female patients with borderline personality disorder
    Alexandra Philipsen
    Department of Psychiatry and Psychotherapy, University of Freiburg Medical School, Freiburg, Germany
    J Clin Psychiatry 65:1414-9. 2004
    ....
  16. ncbi request reprint Elevated pain thresholds correlate with dissociation and aversive arousal in patients with borderline personality disorder
    Petra Ludäscher
    Department of Psychiatry and Psychotherapy, University of Freiburg Medical School, Germany
    Psychiatry Res 149:291-6. 2007
    ..Measuring electric pain thresholds is a valid and reasonable method for larger studies...
  17. doi request reprint Neural and psychophysiological markers of delay aversion in attention-deficit hyperactivity disorder
    Gregor Wilbertz
    Department of Psychology, University of Freiburg, Freiburg, Germany
    J Abnorm Psychol 122:566-72. 2013
    ..Patients also exhibited increased emotional arousal on physiological measures. These results support the notion of an exacerbated negative emotional state during the anticipation and processing of delay in ADHD...
  18. pmc Clarifying the role of the rostral dmPFC/dACC in fear/anxiety: learning, appraisal or expression?
    Simon Maier
    Department of Psychiatry and Psychotherapy, University Medical Center Freiburg, Freiburg im Breisgau, Germany
    PLoS ONE 7:e50120. 2012
    ..We discuss the broader implications of this finding for our understanding of mPFC/ACC function in fear and in negative emotion more generally...
  19. doi request reprint Severity of childhood attention-deficit hyperactivity disorder--a risk factor for personality disorders in adult life?
    Swantje Matthies
    Department of Psychiatry and Psychotherapy, University Medical Centre Freiburg, Hauptstr 5 D 79104, Freiburg, Germany
    J Pers Disord 25:101-14. 2011
    ..Applying the IPDE we confirmed a high number of PDs among adult ADHD patients. Our findings point to a higher vulnerability for the development of PDs in patients with severe childhood ADHD...
  20. pmc Hippocampus and amygdala morphology in adults with attention-deficit hyperactivity disorder
    Evgeniy Perlov
    Department of Psychiatry and Psychotherapy, University Hospital Freiburg, Freiburg, Germany
    J Psychiatry Neurosci 33:509-15. 2008
    ..We sought to test the hypothesis that, like in pediatric patients, there might be hippocampus and amygdala volume abnormalities in adult patients with ADHD...
  21. doi request reprint Spectroscopic findings in attention-deficit/hyperactivity disorder: review and meta-analysis
    Evgeniy Perlov
    Department of Psychiatry and Psychotherapy, University Hospital Freiburg, Freiburg, Germany
    World J Biol Psychiatry 10:355-65. 2009
    ..In this paper we review published MRS results with respect to childhood, adolescence and adult ADHD...
  22. pmc Polysomnography findings in patients with restless legs syndrome and in healthy controls: a comparative observational study
    Magdolna Hornyak
    Center for Sleep Research and Sleep Medicine, Department of Psychiatry and Psychotherapy, University Medical Center Freiburg, Germany
    Sleep 30:861-5. 2007
    ..Sleep disturbances and their sequelae are the most common complaints of patients with restless legs syndrome (RLS). We compared polysomnography (PSG) findings in a large cohort of patients with idiopathic RLS and of healthy subjects...
  23. doi request reprint Visual cortex abnormalities in adults with ADHD: a structural MRI study
    Johannes Ahrendts
    Section for Experimental NeuroPsychiatry, Department of Psychiatry and Psychotherapy, University of Freiburg Medical Center, Freiburg, Germany
    World J Biol Psychiatry 12:260-70. 2011
    ..The aim of this study was to clarify the involvement of prefronto-striatal and posterior parietal areas in adult ADHD...
  24. doi request reprint Neural correlates of interference inhibition, action withholding and action cancelation in adult ADHD
    Alexandra Sebastian
    Department of Psychiatry and Psychotherapy, Albert Ludwigs University Freiburg, Germany
    Psychiatry Res 202:132-41. 2012
    ....
  25. pmc Retinal contrast transfer functions in adults with and without ADHD
    Emanuel Bubl
    Department of Psychiatry and Psychotherapy, Albert Ludwigs University of Freiburg, Freiburg, Germany
    PLoS ONE 8:e61728. 2013
    ..As the contrast gain in an earlier study clearly separated the patients with depression from the controls, we assume that retinal contrast gain might be a specific marker in depression...
  26. doi request reprint Orbitofrontal reward sensitivity and impulsivity in adult attention deficit hyperactivity disorder
    Gregor Wilbertz
    Department of Psychiatry and Psychotherapy, University Hospital Freiburg, Germany
    Neuroimage 60:353-61. 2012
    ..Reward value processing difficulties in ADHD should be considered when assessing reward anticipation and emotional learning in research and applied settings...
  27. ncbi request reprint Increased diurnal salivary cortisol in women with borderline personality disorder
    Klaus Lieb
    Department of Psychiatry and Psychotherapy, University of Freiburg Medical School, Hauptstr 5, D 79104 Freiburg, Germany
    J Psychiatr Res 38:559-65. 2004
    ..Increased adrenal activity and lowered feedback sensitivity of the HPA-axis may characterise BPD. Further studies have to reveal reasons of heightened adrenal activity in these patients...
  28. ncbi request reprint Differential diagnosis and comorbidity of attention-deficit/hyperactivity disorder (ADHD) and borderline personality disorder (BPD) in adults
    Alexandra Philipsen
    Department of Psychiatry and Psychotherapy, University of Freiburg Medical School, Hauptstr 5, 79104, Freiburg, Germany
    Eur Arch Psychiatry Clin Neurosci 256:i42-6. 2006
    ....
  29. ncbi request reprint No association between a common haplotype of the 6 and 10-repeat alleles in intron 8 and the 3'UTR of the DAT1 gene and adult attention deficit hyperactivity disorder
    Daniel Brüggemann
    Department of Genetic Epidemology, Central Institute of Mental Health, Mannheim, Germany
    Psychiatr Genet 17:121. 2007
  30. ncbi request reprint Psychiatric comorbidity and functional impairment in a clinically referred sample of adults with attention-deficit/hyperactivity disorder (ADHD)
    Esther Sobanski
    Department of Psychiatry and Psychotherapy Central Institute of Mental Health, J 5, 68159 Mannheim, Germany
    Eur Arch Psychiatry Clin Neurosci 257:371-7. 2007
    ....
  31. ncbi request reprint Corpus callosum dysplasia in adult attention-deficit/ hyperactivity disorder: a case report
    Alexandra Philipsen
    J Clin Psychiatry 68:1985-8. 2007
  32. ncbi request reprint Differential nociceptive deficits in patients with borderline personality disorder and self-injurious behavior: laser-evoked potentials, spatial discrimination of noxious stimuli, and pain ratings
    Christian Schmahl
    Institute of Physiology and Pathophysiology, Johannes Gutenberg University, Mannheim, Germany
    Pain 110:470-9. 2004
    ..These findings suggest that hypoalgesia in BPD may primarily be due to altered intracortical processing similar to certain meditative states...