Louis Perusse

Summary

Affiliation: University of Kiel
Country: Germany

Publications

  1. pmc Dietary restriction during development enlarges intestinal and hypodermal lipid droplets in Caenorhabditis elegans
    Daniela Palgunow
    Department of Molecular Prevention, Institute of Human Nutrition and Food Science, Christian Albrechts University of Kiel, Kiel, Germany
    PLoS ONE 7:e46198. 2012
  2. pmc Sex differences in carbohydrate metabolism are linked to gene expression in Caenorhabditis elegans
    Claudia Miersch
    Department of Molecular Prevention, Institute of Human Nutrition and Food Science, Christian Albrechts University of Kiel, Kiel, Germany
    PLoS ONE 7:e44748. 2012
  3. pmc Ubiquinol affects the expression of genes involved in PPARα signalling and lipid metabolism without changes in methylation of CpG promoter islands in the liver of mice
    Constance Schmelzer
    Leibniz Institute for Farm Animal Biology FBN, Research Unit Nutritional Physiology Oskar Kellner, Dummerstorf, Germany
    J Clin Biochem Nutr 50:119-26. 2012
  4. pmc Ubiquinol decreases monocytic expression and DNA methylation of the pro-inflammatory chemokine ligand 2 gene in humans
    Alexandra Fischer
    Institute for Human Nutrition and Food Science, Department of Molecular Prevention, Christian Albrechts University, Kiel, Germany
    BMC Res Notes 5:540. 2012
  5. pmc Ascorbic acid partly antagonizes resveratrol mediated heme oxygenase-1 but not paraoxonase-1 induction in cultured hepatocytes - role of the redox-regulated transcription factor Nrf2
    Anika E Wagner
    Institute of Human Nutrition and Food Science, Christian Albrechts University of Kiel, Germany
    BMC Complement Altern Med 11:1. 2011
  6. pmc Association between genetic variants in the Coenzyme Q10 metabolism and Coenzyme Q10 status in humans
    Alexandra Fischer
    Institute of Human Nutrition and Food Science, Devision of Molecular Prevention, Christian Albrechts University of Kiel, Heinrich Hecht Platz 10, 24118 Kiel, Germany
    BMC Res Notes 4:245. 2011
  7. pmc Paraoxonase 1 polymorphism Q192R affects the pro-inflammatory cytokine TNF-alpha in healthy males
    Kai Lüersen
    Institute of Human Nutrition and Food Science, Molecular Prevention, Christian Albrechts University of Kiel, Heinrich Hecht Platz 10, 24118 Kiel, Germany
    BMC Res Notes 4:141. 2011
  8. doi request reprint Ubiquinol-induced gene expression signatures are translated into altered parameters of erythropoiesis and reduced low density lipoprotein cholesterol levels in humans
    Constance Schmelzer
    Department of Molecular Prevention, Institute of Human Nutrition and Food Science, Christian Albrechts University of Kiel, Heinrich Hecht Platz 10, Kiel, Germany
    IUBMB Life 63:42-8. 2011
  9. doi request reprint Single nucleotide polymorphisms in the myostatin (MSTN) and muscle creatine kinase (CKM) genes are not associated with elite endurance performance
    F Doring
    Department of Molecular Prevention, Institute of Human Nutrition and Food Science, Christian Albrechts University, Kiel, Germany
    Scand J Med Sci Sports 21:841-5. 2011
  10. ncbi request reprint ACBP knockdown leads to down-regulation of genes encoding rate-limiting enzymes in cholesterol and fatty acid metabolism
    Christina Vock
    Molecular Prevention, Christian Albrechts University of Kiel, D 24118 Kiel, Germany
    Cell Physiol Biochem 25:675-86. 2010

Collaborators

Detail Information

Publications12

  1. pmc Dietary restriction during development enlarges intestinal and hypodermal lipid droplets in Caenorhabditis elegans
    Daniela Palgunow
    Department of Molecular Prevention, Institute of Human Nutrition and Food Science, Christian Albrechts University of Kiel, Kiel, Germany
    PLoS ONE 7:e46198. 2012
    ..elegans. These changes might be an effective adaptation to conserve fat stores in animals subjected to limiting food supply during development...
  2. pmc Sex differences in carbohydrate metabolism are linked to gene expression in Caenorhabditis elegans
    Claudia Miersch
    Department of Molecular Prevention, Institute of Human Nutrition and Food Science, Christian Albrechts University of Kiel, Kiel, Germany
    PLoS ONE 7:e44748. 2012
    ..In conclusion, we found sex differences in carbohydrate metabolism that are linked to gene expression and identified certain lectin genes that are differentially expressed by the C. elegans sexes...
  3. pmc Ubiquinol affects the expression of genes involved in PPARα signalling and lipid metabolism without changes in methylation of CpG promoter islands in the liver of mice
    Constance Schmelzer
    Leibniz Institute for Farm Animal Biology FBN, Research Unit Nutritional Physiology Oskar Kellner, Dummerstorf, Germany
    J Clin Biochem Nutr 50:119-26. 2012
    ..In conclusion, ubiquinol affects the expression of genes involved in PPARα signalling and lipid metabolism without changing the promoter DNA methylation status in the liver of mice...
  4. pmc Ubiquinol decreases monocytic expression and DNA methylation of the pro-inflammatory chemokine ligand 2 gene in humans
    Alexandra Fischer
    Institute for Human Nutrition and Food Science, Department of Molecular Prevention, Christian Albrechts University, Kiel, Germany
    BMC Res Notes 5:540. 2012
    ..Here we investigate the putative link between expression and DNA methylation of ubiquinol sensitive genes in monocytes obtained from human volunteers supplemented with 150 mg/ day ubiquinol for 14 days...
  5. pmc Ascorbic acid partly antagonizes resveratrol mediated heme oxygenase-1 but not paraoxonase-1 induction in cultured hepatocytes - role of the redox-regulated transcription factor Nrf2
    Anika E Wagner
    Institute of Human Nutrition and Food Science, Christian Albrechts University of Kiel, Germany
    BMC Complement Altern Med 11:1. 2011
    ..However, little is known about the underlying mechanisms for potential health benefits of resveratrol and its interactions with ascorbic acid...
  6. pmc Association between genetic variants in the Coenzyme Q10 metabolism and Coenzyme Q10 status in humans
    Alexandra Fischer
    Institute of Human Nutrition and Food Science, Devision of Molecular Prevention, Christian Albrechts University of Kiel, Heinrich Hecht Platz 10, 24118 Kiel, Germany
    BMC Res Notes 4:245. 2011
    ..abstract:..
  7. pmc Paraoxonase 1 polymorphism Q192R affects the pro-inflammatory cytokine TNF-alpha in healthy males
    Kai Lüersen
    Institute of Human Nutrition and Food Science, Molecular Prevention, Christian Albrechts University of Kiel, Heinrich Hecht Platz 10, 24118 Kiel, Germany
    BMC Res Notes 4:141. 2011
    ..abstract:..
  8. doi request reprint Ubiquinol-induced gene expression signatures are translated into altered parameters of erythropoiesis and reduced low density lipoprotein cholesterol levels in humans
    Constance Schmelzer
    Department of Molecular Prevention, Institute of Human Nutrition and Food Science, Christian Albrechts University of Kiel, Heinrich Hecht Platz 10, Kiel, Germany
    IUBMB Life 63:42-8. 2011
    ..In conclusion, Q(10) H(2) induces characteristic gene expression patterns, which are translated into reduced LDL cholesterol levels and altered parameters of erythropoiesis in humans...
  9. doi request reprint Single nucleotide polymorphisms in the myostatin (MSTN) and muscle creatine kinase (CKM) genes are not associated with elite endurance performance
    F Doring
    Department of Molecular Prevention, Institute of Human Nutrition and Food Science, Christian Albrechts University, Kiel, Germany
    Scand J Med Sci Sports 21:841-5. 2011
    ..We conclude that common variants of MSTN and CKM genes do not play a role in attaining high-level endurance performance in Caucasian populations...
  10. ncbi request reprint ACBP knockdown leads to down-regulation of genes encoding rate-limiting enzymes in cholesterol and fatty acid metabolism
    Christina Vock
    Molecular Prevention, Christian Albrechts University of Kiel, D 24118 Kiel, Germany
    Cell Physiol Biochem 25:675-86. 2010
    ..This effect seems to be translated into certain metabolites. The identified 454 ACBP regulated genes present a first reference for further studies to define the ACBP regulon in mammalian cells...
  11. ncbi request reprint A common haplotype and the Pro582Ser polymorphism of the hypoxia-inducible factor-1alpha (HIF1A) gene in elite endurance athletes
    Frank Döring
    Department of Molecular Prevention, Institute of Human Nutrition and Food Science, Christian Albrechts University, Heinrich Hecht Platz 10, 24118 Kiel, Germany
    J Appl Physiol (1985) 108:1497-500. 2010
    ..93, 95% CI: 0.58-1.50, P=0.769). We found preliminary evidence that the HIF1A Pro582Ser polymorphism and a common haplotype of the HIF1A gene may be associated with EEA status in Caucasian men...
  12. doi request reprint ACTN3 R577X and other polymorphisms are not associated with elite endurance athlete status in the Genathlete study
    Frank E Döring
    Institute of Human Nutrition and Food Science, Christian Albrechts University Kiel, Kiel, Germany
    J Sports Sci 28:1355-9. 2010
    ..In conclusion, our findings indicate that ACTN3 R577X and other SNPs in ACTN3 are not genetic determinants of endurance performance in Caucasian males...